مجله زنان مامائی و نازائی ایران
سال هجدهم شماره 142 (هفته چهارم فروردین 1394)

Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting during pregnancy which occurs in 0.5 to 2% of pregnancies. Its etiology is unknown, hormonal and psychological factors are attributable to the condition. In the recent studies, helicobacter pylori infection has been proposed as possible factor. This study was performed with the aim to evaluate the relationship between helicobacter pylori infection and nausea and vomiting during pregnancy.

This prospective and case-control study was performed on 87 pregnant women referred to Ghaem and Imam Reza hospitals, Mashhad University of Medical Sciences from 2007-2008. Forty three pregnant women with hyperemesis gravidarum and forty four pregnant women without symptom were evaluated in terms of helicobacter pylori infection with serology of IgG antibody against Helicobacter pylori. Analysis of data was performed using SPSS statistical software (version 16) and chi-square and t-student tests.

In this study, 36 women of cases group (81.8%) and 25 women of control group (58.1%) had high serology of IgG antibody against Helicobacter pylori and this difference was statistically significant (P=0.016)

there is a significant relation between hyperemesis gravidarum and positive IgG antibody against Helicobacter pylori.

Iron deficiency anemia (ADI) is the most common cause of anemia in pregnant women that occurs in 15% to 25% of pregnancies. According to WHO report, the prevalence of anemia is 56% in developed countries and 20% in developing countries. This study was performed with aim to evaluate the relation between anemia during pregnancy and birth weight. In this retrospective and descriptive-analytic study, the records of 504 pregnant women who were otherwise healthy and free of disease were evaluated. Pregnant women who their pregnancy had led to term live birth during the past 10 years were enrolled to the study by census sampling method. Patient's information were collected with checklist based on their records. Checklist included two sections of personal characteristics of mothers and neonate's weight. Data was analyzed with SPSS statistical software (version 16) and chi-square and independent t tests. Mean neonatal birth weight was 2942±467 gr. 130 neonates (25.8%) had birth weight Frequency of anemia during the second and third trimester of pregnancy is significantly higher in the mothers of neonates with birth weight <2500 gr than the mothers of neonates with normal weight.

Depression during pregnancy is a significant predictor of postpartum depression which is harmful to fetal development. According to the World Health Organization, depression is the most important cause of disability among women worldwide. This study was performed with aim to evaluate the relationship between depression during pregnancy with social support and some demographic variables. This descriptive-analytical and cross-sectional study was performed on 208 pregnant women referred to health care centers of Gonabad in 2014. To collect data, demographic questionnaire, Edinburg depression scale, and social support appraisals were used. Data was analyzed with SPSS statistical software (version 21) and correlation coefficient test and linear regression test. The average age was 27/5±5/2 and 30 percent of them were depressed. Generally there was statistically significant inverse relationship between the three sources of social support (friends, family and acquaintances) with depression during pregnancy. According to the results of linear regression test, the variables of social support, economic status and gender of the fetus were the most important predictor variables of depression during pregnancy, respectively (P<0/001). Pregnant women who have high social support are less likely to face with depression during pregnancy. The results can be used in the prevention and treatment of this problem.