مجله علمی پزشکی جندی شاپور
سال چهاردهم شماره 5 (پیاپی 98، آذر و دی 1394)

The purpose of this research was study the efficacy of quality of life group therapy on happiness, life satisfaction and emotional regulation of addict men. Subjects and

The research method was semi-experimental with pre-post and control group. The sample consisted of 30 addict males who referred to withdrawal clinics in Ahvaz who acquiring one standard deviation below the mean in happiness scale. Then randomly divided in to experimental and control groups. We used 8 sessions of quality of life group therapy in experimental group but the control group did not receive any intervention. The instrument was Oxford Happiness Inventory and Garnefski Emotional regulation scale.

A significant difference between two groups in happiness, life satisfaction and emotional regulation (P<0.001).The rat of happiness(P<0.001, F=74.26) life satisfaction(P<0.001, F=47.87) and emotional regulation(P<0.001,F=31.24) in experimental group in comparison with pretest and control group was significantly higher.

According to results of this research quality of life therapy as the combined of positive psychology and cognitive behavioral therapy can increase the rate of happiness, life satisfaction and emotional regulation of addict men.

Hemoglobinopathies are the most common monogenic disorders with remarkable frequency in certain regions of the world, including Iran. At least 5.2% of world population is carrier for a main hemoglobin (Hb) disorder. More than 900 Hemoglobin variants were reported due to globin gene mutations that cause structural changes in globin gene products which ultimately affect the performance and stability of hemoglobin. The aim of this study was to evaluate the prevalence of hemoglobinopathies in premarriage men referred to the laboratories of Health Centers in the Shushtar City during the years 2011-2013. Subjects and Hematological parameters in blood samples containing EDTA were measured by Hematology Analyzer (Sysmex KX-21). Hemoglobin electrophoresis was performed by Sebia capillary electrophoresis and types of hemoglobinopathies were determined. 111 cases from total 8806 cases were has abnormal bands of hemoglobin. From this total, 3 cases (0.03%) were with heterozygous hemoglobin E and 1 case (0. 01%) was heterozygous hemoglobin C. Also, 74 cases (0.84%) had hemoglobin D, and 28 patients (0.32%) containing hemoglobin S were with different genotype status; homozygous or heterozygous types. In this study, uncommon Hemoglobin variants (with the prevalence of 0.05%) such as hemoglobin O- Arab and constant spring was observed. This study showed that from 8806 individuals, 111 subjects (1.25%) have hemoglobinopathies. HbD with 0.84% and HbC with 0. 01% of total have highest and minimum frequency.

Pulpectomy is one of the most common treatments for preserving infected primary teeth. Intracanal medicaments have been used to decrease the amount of microorganism. The purpose of present study was to evaluate and compare the antimicrobial effect of some medicaments (formocresol, CMCP and 0.2% chlorhexidine) against some common bacteria isolated from infected primary teeth. Subjects and In this experimental study fifty primary canine teeth were prepared and were randomly divided into 5 groups (n = 10). After sterilization, suspension of bacteria (Streptococcus mutans, Bacillus subtilis, Enterococcus faecalis and Pseudomonas aeruginosa) were inoculated into each canal. Cotton soaked in normal saline as a positive control; and cotton soaked in Formocresol; CMCP and 0.2% chlorhexidine were placed in canal groups(2 to 4). The antibacterial effect of each medicament was evaluated by determining the percentage reduction in colony counts (RCC %) and CFU (colony-forming units) on day 3 after exposure. Kruskal-Wallis test, Dunn's test and SPSS 22 were used to analyze the data. All experimental groups showed a significant decrease in bacterial counts in compassion with control group (P < 0.05). 0.2% chlorhexidine showed significantly lower efficacy compared to formocresol and CMCP group (P < 0.05). According to the present study formocresol and CMCP have good antimicrobial effect.

Exercise can lead to angiogensis and development of capillary network. The aim of this study was to assess the effect of interval training on plasma level of vascular endotheliom growth factor (VEGF) and myocardial capillary density in male and femal rats. Subjects and Sixty male and female rats with same average Age and weight were selected for investigation. Plasma VEGF Level was measured by special kit by ELIZA method before and after exercise training. Cardiac tissue was extracted for measuring capillary density in myocardium by immonohistochemical technique. No significant differences were found between the baseline of VEGF level and myocardial capillary density in male and female rats. Following 8 weeks physical development there were no significant differences between VEGF level and myocardial capillary density in sham and control groups. Whereas level of VEGF and myocardial capillary density increased significantly following interval training, but no significant differences between male and female rats in training groups. According to the finding of the present study interval training is equally effective in increasing VEGF level in both sexes leading to improved angiogenesis in rat myocardial.

Obesity is a complex chronic condition which is defined as an increase in body fat. Today obesity has become a major public health problem in the world, so with the increasing prevalence of obesity, the prevalence of adverse effects associated with obesity increases. The amount of body fat is more important than weight that due to some advanced techniques, we are able to assess it. But difficulty and high cost of these procedures, recalls the need to find an alternative method. Subjects and In this study, 272 Ahvaz students were selected using stratified random sampling and body Fat Percentage by the Bioelectrical impedance analysis (BIA) devices and their anthropometric characteristics were assessed. Strong correlation between AVI, BMI and WHtR in men and BMI, BAI and WHtR in women with percentage of body fat have been observed. Linear regression models were created to predict percentage body fat from anthropometric variables so that the variables sex, BMI, AVI described 85% of body fat percentage differences. Our regression model enables us in estimating body fat without using body composition techniques, using only height gauges and scales.

The aim of this study was to determine the effect of 6 weeks of exercise in water and ginger supplementation on cardio metabolic risk factors in obese women with breast cancer. Subjects and Breast cancer patients included 40 women with a mean age (48±5.8 yr), weight (76 ± 9 kg) and fat mass (41.8±4 kg) were randomly divided into four groups; the placebo, exercise in water + placebo, ginger supplementation and ginger supplements + exercise in water groups. Ginger supplement was consummated for 6 weeks orally 4 capsule (750 mg). Progressive exercise protocol in the exercise in a pool with a width of 15 meters and a depth of 4 meter, 4/week, a sesstion 60-75 min, for 6 weeks. Data of the adiponectin and insulin resistance index were collected at pre-test and post-test and measured by Elisa and HOMA-IR methods, respectively. Both ginger supplementation and exercise in the water lead to an increase adiponectin, reduce insulin, insulin resistance and blood glucose was higher than before. However, the combination group showed higher increase of adiponectin and decrease in insulin resistance concentration, as compared to each separate experiment. These findings show a protective effect of non-pharmacological strategies such as exercise, ginger supplementation and exercise in waster on the cardio-metabolic risk factors in obese women with breast cancer.

Oral Lichen Planus (OLP) is a chronic and precancerous disease. The imbalances between the levels of free radical and antioxidants may play an important role in the onset and development of several inflammatory oral pathologies such as Lichen Planus. Melatonin as an antioxidant can play a role in scavenging free radicals and prevent OLP conversion to cancer. The aim of this study was to evaluate melatonin level in patients with OLP. Subjects and In this analytical study twenty two patients diagnosed with OLP, were recruited as patients group, and twenty age- and sex-matched healthy volunteers were recruited as control group. Melatonin levels in whole unstimulate saliva (WUS) was determined by ELISA test. Statistically analyzed was carried out with LSD and Duncan test. The mean saliva melatonin levels in patients with OLP was lower than those of healthy control group, but it was not statistically significant (P=0.3). The mean saliva melatonin levels in patients with reticular type of OLP compared with control group was significantly decreased (P<0.05) but in erythematose/ulcerative type was not statistically significant (P>0.05). The findings of this study demonstrated that the level of melatonin was decreased in patients with Licben planus, and supports the notion that more attention to treatment of this much neglected disease need to be made. These findings also suggest that the low level of this antioxidant may lead to more destructive injury and put the patients at risk of development of oral cancer.

Recently, electron beams are widely used for superficial and skin lesions treatment. Since the accelerator devices, create electron beams with finite energies, the treatment area is limited to a specified depth. The objective of this study was to assess the effect of combination of electron beams with different energies and different contribution in order to produce PDD curve with a more uniform central dose distribution for the shallow superficial lesions treatment (up to cm 3). The results were compared with using a single electron beam energy. Subjects and at First, percentage depth dose (PDD) was measured by using a Varian accelerator devices for energies 4, 6, 9, 12 Mev of electron beams and field size 20 × 20 cm2. Then, PDD curve was converted to dose curve. 4 Gaussian function was fit to dose curve using MATLAB software and the best combination was selected by combining different proportions of each of this functions. percentage of the build up dose increased to about %90-%95 maximum dose and also percentage of the surface dose increases to about %90 maximum dose by combination of electron beams with different energies and different contribution. low energy electron beams Combination cause optimization of the dose distribution PDD curve. Furthermore, we can produce electron beam with arbitrary energy by this method.

Infertility is a common condition with important psychological, economic, demographic, and medical implications. Demand for infertility services has grown substantially even though the prevalence of infertility has been stable. The aim of this study was to evaluate the acute effect of single dose of sildenafil on seminal parameters in young, infertile patients with oligoasthenospermia. Subjects and Twelve young, infertile men with oligoasthenospermia from an academic hospital as well as a male infertility center and clinical andrology laboratories were enrolled in to this study. A single dose of sildenafil (50 mg) administered and the semen samples were collected 1 hour after treatment. Changes in sperm parameters evaluated after sildenafil administration, compared with the basal conditions. Sperm progressive motility improved (median value, 32.7 % vs. 28.2%) 1 hour after the administration of 50mg sildenafil as well as semen pH (median value 7.82 vs 7.94). No significant changes in sperm morphology, total sperm motility, rapid progressive sperm motility, semen volume and sperm concentration after sildenafil treatment. The data suggest that single dose of Sildenafil causes improvement in sperm progressive motility in patients with oligoasthenospermia.

Patellofemoral pain syndrome (PFPS) is the most common knee disorder. Reduced proprioception, pain and changes in muscle activity patterns have been observed in PFPS. These variables have an effect on the ability to maintain the balance. So it is possible that balance be weaker in PFPS. The purpose of this study was to evaluate the effects of patellar taping on balance in patients with PFPS and healthy people. Subjects and This study was performed on two groups of 15 women with PFPS and healthy by non-probability convenient sampling method. The ability to maintain of balance was measured with use of clinical functional balance tests (Balance and Reach, Anteromedial Lunge, Unilateral Squat, Step down) under tape and no-tape conditions on involved leg of patient and matching leg in control group. Relative to healthy population, patients with PFPS demonstrated significant decreased in mean repetitions of all functional balance tests (P<0/001). Patellar taping produced a significant increased in mean repetitions of three functional balance tests (Balance and Reach, Anteromedial Lunge, Unilateral Squat) in all of participants (P<0/001). No different significant between patient and control groups in step down test. The results of our investigation demonstrated that, in comparison with healthy subjects, patients with PFPS had poorly balance. Patellar taping is effective in improvement of balance in patients with PFPS.

Nowadays the therapeutic methods are being shifted toward “targeted therapy” which means specific therapy against one expressed factor in cancerous tissue. In recent years several indicators for evaluating the prognosis of breast cancer have been under investigation. One of these is fibroblast growth factor receptor (FGFR2). Fibroblast growth factors play multiple physiological roles and in some studies have been regarded as effective parameter in prognosis of breast cancer while it has not been the case in other studies. Subjects and The effects of them are exerted via their receptors.A retrospective study was applied. Immunohistochemical method was applied. Also, statistical analysis was done. No statistical correlation between FGFR2 and tumor size, age, microscopic grade and auxiliary lymph node metastasis were found. We did not find any correlation. It is suggested that the study be performed in larger scale and other parameters be included in the survey. Furthermore, such survey should be performed concerning other common cancers. Also, some pilot medicines must be assessed in a clinical trial.

Nasopalatine duct cysts are the most common of developmental non-odontogenic cysts in the oral cavity and represent 10% of maxillary cysts. The cyst arises from epithelial remnants from the nasopalatine duct. These cysts are usually asymptomatic, but the most commonly reported clinical symptom is swelling in the anterior part of the palate, just behind the palatal papilla. This swelling is not always on midline. The recurrence of this is rare (2%). In this report, a 21-year-old man from Ahvaz, with the chief complaints of numbness, anterior teeth mobility, intraoral swelling and facial asymmetry, is reported. On clinical examination, a nontender swelling on the midline of hard palate and buccal vestibule, covered by normal mucosa was seen. The crown of central incisors was displaced mesially. In panoramic, maxillary occlusal cross sectional, anterior maxillary periapical and computed tomography views, a well-defined unilocular radiolucency with corticated margins was seen in the anterior region of maxilla. Biopsy of the lesion was planned and final pathologic diagnosis was “nasopalatine duct cyst”. Therefore, nasopalatine duct cyst is one of the differential diagnoses of unilocular radiolucencies in the anterior region of maxilla. Histopathologic examinations help us to reach the correct diagnosis and disburden us from unnecessary treatments.