Omega 3 fatty acids supplements and ischemic reperfusion injuries in heart, brain and kidney tissues

Ischemia that followed by reperfusion can couse severe damages in tissues and organs and can be occurred in clinical condition such as surgeries, cardiovascular heart diseases, heart attack and stroke, trauma, sepsis, Etc which are caused perfusion and oxygen reduced and then reperfusion occurred. The results of many studies have been shown that dietetic treatment with fatty acids can reduce complication of ischemic reperfusion significantly. Pubmed, Science direct, Springer and Google scholar databases were searched in order to achieve the desired articles. Cellular, animal as well as human studies that have been conducted from 1990 till 2012, were recruited in this investigation.. The results of previous studies have been shown that intake of omega 3 fatty acids (after 4 weeks) increase the amount of long-chain polyunsaturated fatty acids in the left ventricular wall and decrease the accumulation of leukocytes in the heart. In addition, the results of other studies have been indicated that omega 3 fatty acids dietary treatment can reduce tachycardia and atrial fibrillation in mice. Also, long-term treatments with polyunsaturated fatty acids indicate positive results in the isolated heart model. Treatment with unsaturated fatty acids such as omega 3 befor tissue ischemia are able to resistance the cells. Also, improve the function of tissues special myocard after ischemic injury. In addition, studies indicated that effects of dietetic treatment with omega 3 in comparing with omega 6 are more effective and can be clinical uses.