Study of variances in some blood factors during sepsis diagnosis and their interrelations

Sepsis is one of the most common reasons of mortality among patients in intensive care unit، worldwide. Despite new supportive treatments and administration of high potent antibiotics، sepsis is overwhelmingly one of the risky factors in patient’s life. This study was carried out to compare values of some of the blood tests in sepsis diagnosis and to examine their interrelations in order to select a more practicable diagnosis method. In this descriptive-analytical study، 30 patients with sepsis، hospitalized at ICU were selected. Erythrocyte sedimentation rate (ESR)، C-reactive protein (CRP)، Platelet (PLT)، and White blood cells (WBC) were measured in three stages: pre-sepsis، peri-sepsis، and post sepsis. Data analysis was conducted by SPSS using repeated measures ANOVA and paired t-test. ESR، CRP، PLT، and WBC in peri sepsis were significantly higher than those in pre sepsis and post-sepsis (P<0. 05). Comparing PCT mean level in post-sepsis was significantly lower than those in pre sepsis and post sepsis (P<0. 05). Regarding the significant difference in ESR، CRP، and WBC in peri sepsis compared to pre - and post-sepsis in this study، these tests might be used as simple and inexpensive ones instead of PCT and C3 tests for the diagnosis of sepsis in ICU.