The effect of 3 weeks ergometer cycling training with and without vascular occlusion on Plasma concentration of Irisin and PGC-1α in healthy men

The aim of this study was to investigate the effect of 3 weeks ergometer cycling training with and without vascular occlusion on plasma concentration of Irisin and PGC-1α in healthy men. 24 men of physical education students of Kharazmi University voluntarily participated in this study and divided into three groups (8 subject); ergometer cycling training with vascular occlusion, ergometer cycling training without vascular occlusion and control. The training program included three bouts 3-minute ergometer cycling with 50% watts’ maximum intensity (Wmax) with 30 seconds of rest between each bout, during 3 weeks and 3 sessions training per week. Data were analyzed with t-test and ANOVA at P≤0.05. The results showed that there is a significant difference between the pre-test and post-test Irisin levels in the occlusion (p=0.001) and without occlusion group (p=0.011), but There is no significant difference between the values of irisin pre-test and post-test, the compatibility in the control group (P