The Effect of 8 Weeks of Resistance Training on Plasma Omentin-1 Concentration and Insulin Resistance Index in Obese Men

Omentin-1 is a adipokine with insulin-sensitizing properties. The purpose of this study was to investigate the effect of eight weeks of circuit resistance training on plasma omentin-1 levels in obese men. Twenty eight obese men (age; 35.7 ± 8.0 yr, weight; 95.5 ± 14.3 kg, and BMI; 31.8 ± 4.3) voluntarily participated in this study, and were divided into control (n=12) and resistance training (n=16) groups. Subjects in training group performed eight weeks circuit resistance training with 50-85% 1RM (3 days/week). Anthropometrics parameters and fasting plasma glucose, insulin, and omentin-1 levels, as well as insulin resistance index (HOMA-IR) were measured at the baseline and at the end of study. Resistance training induced significant reductions in body weight, BMI and body fat percentage (P < 0.05). Significant reductions in plasma insulin concentration and HOMA-IR scores were found when compared with control group (P < 0.05). we did not find significant changes in plasma omentin-1 levels. The results of this study indicated that resistance training did not affect plasma omentin-1 levels despite significantly improves in anthropometric and metabolic parameters. Therefore it seems that other mechanisms other than changes in body composition and insulin resistance may be involved in regulating plasma omentin-1 levels.