COMPARISON OF TWO METHODS OF BOWEL PREPARATION: THE EFFICACY OF CASTOR OIL PLUS COTRIMOXAZOLE, METRONIDAZOLE AND CEFTIZOXIME (CCMC), Vs, POLY ETHYLENE GLYCOL PLUS NEOMYCIN, ERYTHROMYCIN AND CEFAMANDOL(PNEC): A RANDOMIZED DOUBLE BLINDED STUDY

To compare colon cleansing and complications after two methods of bowel preparation: castor oil plus Cotrimoxazole – Metronidazole – Ceftizoxime (CCMC) versus Polyethylenglycol plus Neomycin-Erythromycin – Cefamandol (PNEC). Sixty patients scheduled for elective colorectal surgery were randomized to receive above-mentioned regimens. The adequacy of colon cleansing were evaluated by blinded surgeon during operation. Proportion of acceptable cleansing was 90% in CCMC receivers and 96% in PNEC receivers (non Significant, power: 97.5%). Abdominal pain was more common in PNEC receivers compared with CCMC receivers (15%vs. 40%, P<0.05). Infectious complications were seen in 13.3% of CCMC receivers and 10% of PNEC receivers (not statisticaly difference). CCMC regimen is an effective, safe and cheap method for bowel preparation its usage is recommended.