Risk assessment of developing breast cancer by utilizing Gail model in referring persons at the public specialized women hospital

Despite advances in prevention, diagnosis, and treatment, breast cancer remains the most common malignancy and the second leading cause of cancer deaths in women. The Gail model is widely used to quantify an individual woman’s risk of developing breast cancer by utilizing important clinical parameters usually for clinical counseling purposes or to determine eligibility by radiographic and genetic trials. The aim of this study was to estimate the 5-year and life time breast cancer risk in referring persons at Alzahra public women hospital. A cross-sectional study was performed in 1386 of 314 women referring to the different clinics at only public women hospital in Rasht. Participant's ages were 35 and over years with no personal history of breast cancer. Risk estimation was performed utilizing the computerized Gail model provided by the National Cancer Institute with a questionnaire containing 8 questions. A calculated 5-year risk >1.66% was considered high-risk. This model has been validated with at least 5 studies. Data analyzing was done with SPSS.10. The mean age was 45.8± 9.4 years (range 35–81), and 17 (5.4%) patients had at least one first-degree relative with breast cancer. 20 person (6.4%) had biopsy history. Sixteen (5.1%) women had a 5-year risk >1.66%. The mean 5-year risk for all patients was 0.84± 0.99 (range 1-12.5) and lifetime risk was 9± 3.9 (range8-49.4) On the results this group of Rasht women's breast cancer risk is lower comparing mean similar age but for avoiding an increase in the morbidity and mortality of the population, it is necessary that primary care clinics be able to determine risk factors and risk level and presenting high risk persons therefore it is recommended routine utilization of the Gail model for cancer prevention