فرشید رییسی

Agricultural pesticides are widely used all over the world. Relatively, Deltamethrin is a synthetic pyrethroid insecticide used in agriculture. Oxidative stress induction is one of its toxicity mechanisms. It has been found that natural compounds with antioxidant properties play an essential role in maintaining people's health against the dangers of chemicals such as pesticides. Therefore, the present study aimed to investigate the role of acacetin; a natural secondary metabolite, in deltamethrin-induced liver damage in rats.

Thirty-two male Balb/C mice were randomly divided into four groups (8 mice in each group) containing control, acacetin (50 mg/kg), deltamethrin (5 mg/kg/day), and deltamethrin+acacetin. The mice for 2 weeks received 0.01% Dimethyl sulfoxide or deltamethrin (5 mg/kg/day) by gavage and acacetin (50 mg/kg) intraperitoneally. The histopathological changes in liver tissue, serum levels of liver-related enzymes, tissue values of total antioxidant capacity, malondialdehyde, number of apoptotic cells, and inflammatory cytokines were evaluated.

The total antioxidant capacity of liver tissue in the deltamethrin group was significantly lower than the control group. In contrast, other parameters in the deltamethrin group were considerably higher than the control group (P<0.01). A significant increase in the total antioxidant capacity of liver tissue was seen in the deltamethrin+acacetin group compared to the deltamethrin group (P<0.01). At the same time, other studied parameters showed a significant decrease in this comparison (P<0.01).

Acacetin with its antioxidant, anti-apoptotic, and anti-inflammatory properties improves liver tissue damage caused by deltamethrin.

Group B Streptococcus (GBS) or agalactia is an important cause of infection among the early newborns. The bacterium is transmitted from mother to child and most often leads to infant death. The goal of this study was to detect GBS among clinical samples of pregnant women in Kermanshah province, using Colony PCR and standard microbiological culture and then to compare the phenotypic and genotypic methods against each other.
One hundred cases aged at 30- 38 weeks of life were selected during 4 months from April 2014 on at health centers of Kermanshah province. The samples were taken from the women’s vaginal secretions and tested by standard culture using basic culture medium Todd- Hewitt broth, blood agar and Colony- PCR targeting scpB gene.
Findings: The results showed phenotypic test among 100 samples, 5 (5%) as carriers of group B streptococci, compared to 7 patients (7%) by Colony PCR test.
Conclusion & According to our study, the rate of GBS incidence is high in women of Kermanshah. Furthermore, the Colony PCR method that eliminates DNA extraction process can be a rapid, reliable and low cost method to detect the carrier.

he Josephson Fluxonic Diode is a long Josephson Junction that uses oppositely directed magnetic flux quanta, associated with current votrices and antivortices, as its basis operation. the movement of the vortices creates a changing phase. this in turn creates a voltage drop. in this paper, discrete JJ is proposed instead of continues JJ in JFD. Also, by numerical calculation of the discrete sine- Gordon equation, the manner of the carriers is discussed in discrete JJ. Numerically study of the dynamics of JFD based on discrete JJ shows a rectification. Because of it is easy to adjust the value of the junction parammeters, and it is possible to have single flux quantum stuffed in a small area by adjusting the discreetness parameter, it is expected that the useful and practical Josephson fluxonic devices can be made by discrete JJs.

Introduction & Cardiovascular diseases are the main cause of death in all countries in the recent century and congestive heart failure (CHF) is the reason of death in most pa-tients. The most common causes of CHF are ischemic heart disease، myopathies، valvular disease and hypertension. Mortality reduction is the aim in CHF treatment. Combination of glucose-insulin-potassium (GIK) has been used in the treatment of acute coronary syndrome and chronic CHF for two decades and different results reported. The current study performed to evaluate the efficacy of GIK to accelerate resolving signs and symptoms in patients with acute CHF. NT. pro BNP and H. s CRP are two components which increase in acute CHF and decrease after treatment. These parameters were evaluated in our clinical trial study. 50 patients admitted with the diagnosis of acute CHF and EF<40% were divided in two groups and the case group received GIK and control group placebo (half saline). Both groups received the classic treatment of CHF and the above mentioned parameters were measured in the first hour and third and fifth day. Appropriate reduction in both parameters، which means good result in treatment، was observed in both groups but without statistical significant difference. GIK has been used with good results in acute MI and chronic heart failure، but in order to prove better efficacy and decrease in mortality in acute CHF more research is needed.

This paper reports on the photo detection properties of graphene nano layer, based on the fabrication of graphene-Si Schottky diode. To fabricate this Schottky junction, a graphene nano layer has been deposited on Si substrate. The Si substrate is oxidized to 270 nm thickness and is patterned with a specific mask after Cr/Au deposition (the thickness of Cr/Au are 50 nm and 150 nm, respectively). The current-voltage (C-V) curves of the diode are analyzed under 670, 700 and 1100 nm illuminations and also under yellow light radiations. To investigate the photo detection properties of graphene nano layer in Schottky diode structure, 700 and 1100 nm radiations are also illuminated to the backside of the diode and then the photo-generated current under both front and back side illuminations are compared. The experiment results demonstrate that the generated currents in the front side mode and under 700 and 1100 nm illuminations have been increased about 23 and 17 times in comparison with the backside mode. This rise in the current shows the graphene effect in photo detection mechanism and also shows the great amount of photo generated current in graphene in the front side illuminations. The C-V curves of the diode under 670 nm and yellow light illuminations demonstrate not only the photo-generated current but also the photo voltage which shows graphene potential for being used as the solar cell. The optical properties of graphene are also discussed in this paper and many theories which can describe the generation of photo current in graphene are presented.