مقالات رزومه الهه فراهانی

The detection of new variants of COVID-19 still faces challenges due to various observations in human society as well as possible reservoirs in domestic and wild animals, and the prediction of possible future pandemics requires accurate and early detection of viruses. Although different techniques have been used to detect COVID-19, advanced diagnostic assay methods are needed for better and more efficient control of COVID-19. One of the analytical and sensitive techniques for detecting viruses is surface-enhanced Raman spectroscopy (SERS), which provides a fingerprint for any biomolecule. The widespread application of SERS technology in integration with immunoassay methods has provided great achievements in the diagnostic studies of viruses. Likewise, the ultra-sensitive diagnostic ability of the SERS method using substrates based on plasmonic nanostructures has been proven in various biological researches. In addition, by optimizing various conditions such as improving the ability and repeatability of SERS detection and increasing the efficiency of the platforms used for early detection of coronavirus-19, the problems of traditional approaches can be solved. Thus, SERS is a promising option in the early detection of COVID-19 in the recent pandemic. In this review, some diagnostic applications of the SERS technique for the COVID-19 identification are briefly discussed, which we hope will be useful for researchers.

Acute coronavirus syndrome (SARS-CoV-2) leads to the COVID-19 epidemic. In accordance with the WHO, the epidemic remains a serious danger to the general health because of its global spread and higher transmission rates. A scope of measures is needed to slow the spread of the epidemic and save lives, including the continuous assessment and cautious adjustment of general health reactions to the medical treatment. In such a manner, the expansion of antiviral nanostructures by improved surface designing may be valuable in combating this new virus. Quantum dots are multifaceted agents with the potency to fight or prevent the activity of the Coronavirus. For qualitative diagnosis, a simple and inexpensive bioassay method based on Fluorescence-based QDs nanoparticles can be used to detect SARS-CoV-2 antibodies. Optimization of quantum dots with effective functional molecules against SARS-CoV-2 could extend the nanostructures to the antiviral treatment and eradicate future epidemics, slowing down and possibly ending the spread of viral infections. QDs can be used to promote individual clinical therapy in the future based on each patient's molecular protocols individually. This study addresses how quantum dots (QDs) are useful in diagnosing SARS-CoV-2 infection and future pandemics.