aliasghar soleymani

This study aimed to compare the efficacy of buccal infiltration anesthesia (BIA) with 4% articaine versus inferior alveolar nerve block (IANB) with 2% lidocaine for extraction of primary mandibular molars.

This single-blind randomized controlled clinical trial evaluated 100 children between 4-8 years requiring extraction of primary mandibular molars. The children were randomly assigned to two groups (n=50) of IANB with 2% lidocaine and 1:100,000 epinephrine (control), and BIA with 4% articaine and 1:200,000 epinephrine. The Wong-Baker Faces Pain Rating Scale (WBFPS) and the Face, Legs, Activity, Cry, and Consolability (FLACC) scale were used to assess the analgesic efficacy of each technique, and the resultant behavioral reaction of children. Data were analyzed by the Mann-Whitney, Chi-square, and independent t-tests (alpha=0.05). 

In total, 43 girls and 57 boys with a mean age of 6.59±1.20 years were evaluated. The mean FLACC score was 0.98 in the lidocaine and 1.44 in the articaine group with no significant difference (P=0.246). The mean WBFPS score was significantly higher in the articaine than in the lidocaine group (P=0.039), but the difference between the two groups separately for each tooth type was not significant (P>0.05).

Despite the significantly lower pain score of the IANB with lidocaine group, BIA with 4% articaine was comparable to IANB with 2% lidocaine in behavioral control of children, and may be considered as an acceptable alternative.

This study compared the efficacy of buccal infiltration anesthesia (BIA) with articaine versus inferior alveolar nerve block (IANB) with lidocaine for pulpotomy of primary mandibular second molars under intravenous sedation.  

This split-mouth randomized clinical trial was conducted on 29 uncooperative children (Frankl scores I & II) between 3-6 years with bilateral primary mandibular second molars requiring pulpotomy. After intravenous sedation, one random quadrant received IANB with 2% lidocaine and the respective tooth underwent pulpotomy with mineral trioxide aggregate and subsequent coronal restoration with a stainless-steel crown. The other quadrant received BIA with 4% articaine in the next session for pulpotomy of the respective tooth. The behavior of children was evaluated right after receiving the sedative (T0), during anesthetic injection (T1), during pulp exposure (T2), and in the recovery room (T3) using non-verbal pain scale-revised (NVPS-R). Data were analyzed by one-way and two-way repeated measures ANOVA (alpha=0.05). 

The odds of calmness of children during the entire procedure were 1.7 times higher in BIA than IANB but this difference was not significant (P=0.061). The mean heart rate (HR) of children was generally higher in IANB than BIA (P=0.04 at T1, P<0.001 at T2, and P=0.01 at T3). The effect of time on HR was also significant (P<0.001). Blood oxygen saturation rate (SPO2) was higher in BIA than IANB during the procedure (P<0.001).

BIA with articaine had optimal efficacy comparable to that of IANB with lidocaine for pulpotomy of primary second molars under sedation.

Hyper-immunoglobulin E syndrome (HIES),also known asJob's syndrome, is a rare primary immunodeficiency disorder characterized by a classic triad: elevated immunoglobulin E (IgE) levels, recurrent pneumonia with pneumatocele formation, and recurrent cold skin abscesses.

Case:

A 5-year-old girl was referred to the pediatric dentistrydepartment for tooth decay and multiple dental abscesses. Her medical history revealed elevated serum IgE levels, and she was receiving treatment with warfarin due to a history of jugular vein thrombosis. Clinical examination showed numerous skin abscesses alongside multiple eczemas.Angular cheilitis, de-papillation of the tongue, deep furrows on the tongue, numerous intraoral ulcerated lesions, poor oral hygiene, and gingivitis were seen in the intraoral examination.Due to the systemic conditions and thechild's non-cooperation, treatment under general anesthesia was planned.

Dentists play an essential role in the early diagnosis of HIES and in monitoring their oral health conditions. Timely extraction of over-retained primary teeth can reduce the necessity for complex treatments, thereby facilitating the management of patients with Job's syndrome.

 This study aimed to assess the knowledge, attitude, and practice of Iranian pedodontists regarding preventive measures during the coronavirus disease 2019 (COVID-19) pandemic.

This cross-sectional study was conducted on 180 Iranian pedodontists. Data regarding their knowledge, attitude, and practice related to COVID-19 were collected through a valid and reliable researcher-designed questionnaire and analyzed using the independent t-test, analysis of variance (ANOVA), and Tukey test (alpha = 0.05).

The majority of the participants were between 30 and 50 years old. The attitude and practice scores of participants aged over 50 were significantly higher than those of younger participants (P < 0.05). The majority of the participants were female, but the mean practice score of males was significantly higher than that of females (P = 0.018). The participants’ mean knowledge, attitude, and practice scores had no significant association with their work experience or practice location (P > 0.05). The participants had a good level of knowledge regarding self-protection; however, they needed to update their knowledge.  

 The Iranian pedodontists’ levels of knowledge, attitude, and practice were generally good, and they adhered well to the infection control protocols, social distancing measures, and taking thorough medical histories.

Although, oral health is important for its role in the overall health but oral health care does not have an integrated model. So, today meeting the needs of oral health requires strong interactions between health research policy and oral health researchThe aim of this study investigates the effects of ethanolic crud extract of Cuminum cyminum L. on S. mutans in terms of antibacterial, antibiofilm and, its cytotoxicity properties. The present experimental study which has conducted in 2019-2020. The crude alcoholic extract of C. cyminum seeds was prepared by the maceration method. Then, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of crude ethanolic extract of C. cyminum was determined by micro-dilution method according to CLSI protocol on Streptococcus mutans (PTCC1683). In addition, its antibiofilm effect was investigated by the previous method using crystal violet. As well, an MTT test was performed to evaluate its cytotoxicity on SW480 cells. Statistical analysis was done by SPSS V.22 software. MIC and MBC concentrations of C. cyminum extract on S. mutans were found to be 0.62 mg/mL and 1.25 mg/mL. The effect of inhibiting biofilm production was also observed at a concentration of 40 mg/mL.  In MTT assay showed a greater cytotoxic effect on SW480 cancer cells at higher concentrations for longer periods of time. The present study showed that the cumin ethanolic crude extract has antimicrobial properties, inhibits the growth of S. mutans biofilms and has no toxic properties.
MIC: minimum inhibitory concentration. MBC: minimum bactericidal concentration. MTT: 3-(4,5-dimethylthiazol-2-yl) -2,5-diphenyl-2H- tetrazolium bromide. DMSO: dimethyl sulfoxide

Cardiovascular disease is a major cause of death in patients with type 1 diabetes, and cardiovascular risk remains high even in patients with type 1 diabetes with good metabolic control. The aim of this study was to evaluate the effect of six weeks of aerobic exercise on inflammation and damage indicators of heart tissue in type 1 diabetic male rats.

In this experimental study, 19 male Wistar rats (mean weight 200-250 g) were randomly divided into four groups: aerobic training, sham, control and healthy. In this study, induction of type 1 diabetes was performed by injecting a single dose of streptozotocin dissolved in sodium citrate buffer intraperitoneally. Aerobic exercise program was performed with intensity of 50-60% VO2max, 5 days a week for 6 weeks. After anesthesia, an autopsy was performed and left ventricle of the heart was removed. Levels of Tumour necrosis factor α (TNF-α), Peroxisome proliferator-activated receptor-γ coactivator (PGC-1α) and Creatine kinase (CK) in rat heart tissue were measured by Western blotting. Data were analyzed by One-way ANOVA and Tukey post hoc test at the P<0.05.

  The results showed that six weeks of aerobic training led to significant decrease in TNF-α and CK and significant increase in PGC-1α of the heart tissue in type 1 diabetic rats (P<0.001).

  According to the results, it seems that aerobic training can help improve the inflammation and damage indicators of heart in type 1 diabetes.

Amelogenesis imperfecta (AI) refers to a group of hereditary disorders that affect the quality and/or quantity of dental enamel of both primary and permanent dentitions. Also, these patients may suffer from certain systemic disorders and other dental and skeletal defects or abnormalities.

A 9-year-old female patient with hypoplastic type AI with unerupted maxillary first molars, and pulpal calcifications is reported. Her permanent anterior teeth were restored with composite veneer while the posterior teeth received stainless steel crowns.

Hypoplastic type AI is a rather uncommon disorder. Early treatment of AI, not only prevents tooth wear, but also has a positive psychological impact on children. The possible association of AI with nephrocalcinosis can also be monitored through initial radiographic evidence of pulp stones.

Iron supplementation in children under 5 years of age is recommended on the basis of anaemia prevention. This study aims to assess the mother’s knowledge and practice towards the effects of iron supplementation on dental caries and staining in children aged 6 months to 2 years in Yazd, Iran. A randomized cross-sectional study was conducted on 403 mothers of children (aged 6 months to 2 years) who referred to healthcare centers in Yazd during 2011. The mothers' knowledge and practice levels were assessed using a questionnaire, and the results were categorized into sufficient or insufficient. The Chi-square test was used to analyze the data. According to the results, 241 (59.8%), and 273 (67.7%) mothers obtained sufficient levels of knowledge, and practice, respectively. Moreover, mothers’ educational levels had a statistically significant relationship with their knowledge regarding iron supplementation (P<0.001). Additionally, the mother’s practice toward iron supplementation correlated significantly with mothers’ educational level (P<0.001) and occupational status (P=0.018), as well as the birth order of the child (P<0.001). More than half of the mothers had sufficient knowledge and practice towards the effects of iron supplementation on dental caries and staining

Early childhood caries (ECC) is one of the most common problems in children worldwide which is seen in 3-45% preschool children population. Bacterial factor is one of the main four components (time, microorganism, diet, host) to create caries. Streptococcus mutans is one of the most important cariogenic microorganisms. The objective of this study is evaluating Streptococcus mutans count in children with ECC and caries free children considering other factors. The aim of this study was to find the CFU of Streptococcus mutans in saliva of children with ECC versus caries free ones. In addition environmental factors affecting CFU of this micro organism.
Salivary Streptococcus mutans count in 76 3-5 year old children was done in two groups (ECC and caries free). Non stimulated saliva was collected and cultured on Streptococcus mutans specific growth medium. Data was analyzed with Chi-Square, spearman, Kruskal–Wallis,Mann–Whitney tests.
Differences in colony count in study groups were statistically significant and was less in caries free children (p value In the current study, a statistically significant difference was seen in colony count in two groups. Sugar consumption frequency and feeding method had a significant impact on colony count. Micro organisms are still the most important factors in creating caries but feeding pattern and sugar consumption frequency also have an important role. The results also showed that parents educational level does not influence reducing caries which should be noted.

There are several known sedative drugs, with midazolam and ketamine being the most com-monly used drugs in children. The aim of this study was to compare the effect of intranasal and oral midazolam plus ket-amine in children with high levels of dental anxiety. A crossover double-blind clinical trial was conducted on 23 uncooperative children aged 3‒6 (negative or definitely negative by Frankel scale), who required at least two similar dental treatment visits. Cases were randomly given ketamine (10 mg/kg) and midazolam (0.5 mg/kg) through oral or intranasal routes in each visit. The sedative efficacy of the agents was assessed by an overall success rate judged by two independent pediatric dentists based on Houpt’s scale for sedation. Data analysis was carried out using Wilcoxon test and paired t-test. Intranasal administration was more effective in reduction of crying and movement during dental procedures compared to oral sedation (P<0.05). Overall behavior control was scored higher in nasal compared to oral routes at the time of LA injection and after 15 minutes (P<0.05). The difference was found to be statistically significant at the start and during treatment. However, the difference was no longer significant after 30 minutes, with the vital signs remaining with-in physiological limits. Recovery time was longer in the intranasal group (P<0.001) with a more sleepy face (P=0.004). Intranasal midazolam/ketamine combination was more satisfactory and effective than the oral route when sedating uncooperative children.

In recent years, significant developments have been taking place in caries removal and cavity preparation using laser in dentistry. As laser use is considered for cavity preparation, it is necessary to determine the quality of restoration margins. Glass ionomer cements have great applications for conservative restoration in the pediatric field.The purpose of this in vitro study was to compare resin-modified glass ionomer restorations micro-leakage in cavities prepared by Er:YAG (Erbium-Doped Yttrium Aluminum Garnet) laser irradiation and conventional method in primary teeth. This was an in vitro experimental study. Forty primary canine teeth were divided into 2 groups: group 1 represented cavities prepared by the no. 008 diamond bur, group 2 represented cavities prepared by Er:YAG laser. After cavity preparation, samples were restored by resin-modified glass ionomer. The teeth were thermocycled for 700 cycles, placed in 2% methylene blue for 24h and sectioned in the buccolingual direction. The degree of dye penetration was scored by 3 examiners. Data was analyzed using Mann-Whitney Test. There was no statistical difference in micro-leakage between the two modes of cavity preparation (P=0.862) Since preparing conservative cavities is very important in pediatric dentistry, it is possible to use Er:YAG laser because of its novel and portable technology. However, further investigations of other restorative materials and other laser powers are required.

Micro-leakage, one of the major reasons for recurrent decays, may lead to uncontrollable flow of liquids, pulp inflammation and peri-apical pathology. The purpose of this in vitro study was to evaluate micro-leakage of pit and fissure sealants after using three different pit and fissure preparation techniques: 1) acid etching, 2) fissure enameloplasty and acid etching, and 3) air abrasion and acid etching. Sixty-nine extracted sound molars and premolars were randomly divided into three groups (23 samples in each group). Teeth were prepared using one of three occlusal surface treatments. Then the sealant was applied on the occlusal fissures of all teeth. The teeth were thermocycled and stored in normal saline. All teeth were sealed apically and coated with nail varnish and then were immersed in a 2% solution of methylen blue. Two buccolingual sections were made. The surfaces were scored 0 to 3 for the extent of micro-leakage using a stereomicroscope. Data were analyzed by Kruskal- wallis and Dunn procedure. Enameloplasty and acid etching were significantly different regarding micro-leakage (P= 0.016), but no significant difference in micro-leakage was observed between air abrasion and the other methods. Enameloplasty followed by acid etching produced significantly less micro-leakage than the acid etching technique. Air abrasion acid etching was better than the acid etching technique in reducing micro-leakage too.

Background and aims. Marginal seal of the material is extremely important in fissure sealant therapy. The aim of this study was to investigate microleakage of flowable composite resins and conventional fissure sealants with or without dentin bonding agent.Materials and methods. The occlusal surface of 60 intact extracted human premolars, divided into four groups, were cleaned with pumice/slurry, etched with 37% phosphoric acid for 15 seconds, rinsed and dried. Groups were treated differ-ently: Excite bonding agent followed by Helioseal F fissure sealant in group1; Helioseal F alone in group 2; Excite bonding agent followed by Tetric Flow in group 3; and Tetric Flow alone in group 4. Light-curing was done after each application. After thermocycling, the whole surface of each specimen was coated with nail varnish except for one millimeter around the fissure sealant. The teeth were immersed in 2% basic fuchsin for 24 hours and then sectioned buccolingually. The sections were analyzed for leakage under a stereomicroscope. Data was analyzed by Kruskal-Wallis and Mann-Whitney tests at a significance level of P < 0.05. Results. There were no statistically significant differences between the study groups in terms of the mean microleakage scores (P > 0.05), except for groups 2 and 4 (P = 0.002) and groups 3 and 4 (P = 0.033). Conclusion. Use of a flowable composite with bonding agent is a good alternative for sealing pits and fissures; however, further in vitro and in vivo studies are necessary.