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عضویت

فهرست مطالب aliashraf mozafari

  • Maryam Kheiry, Aliashraf Mozafari, Mohamadreza Kaffashian, Amin Kheiri, Masoumeh Shohani, Azra Kenarkoohi, Mahdi Vahabi, Maryam Maleki*
    Introduction

    Effective performance in online education increasingly impacts the quality of classes and, consequently, student learning outcomes. This study aims to compare satisfaction levels and learning rates between online and face-to-face methods of teaching medical physiology.

    Material & Methods

    This cross-sectional descriptive-analytical study involved 79 medical students divided into two groups. The first group received instruction on heart physiology (5 weeks, one session per week) online via the Navid system, while the second group received face-to-face instruction. At the study's conclusion, both groups underwent the same test to assess learning outcomes, and satisfaction with the teaching methods was evaluated through a questionnaire. Data analysis was conducted using Stata 14 statistical software, employing logistic regression and linear regression models.

    Results

    The two groups differed in terms of the course studied, student nativeness, and satisfaction levels with the educational method. Satisfaction with online education was reported at 69%, compared to 65% for the face-to-face method. The average learning score for students in the online group was 12.93±0.12, while in the face-to-face group, it was 13.48±0.47. However, the linear regression model revealed no significant relationship between students' scores and specific educational methods (p=0.32). Significant relationships were observed between age, nativeness, and dormitory accommodation with satisfaction levels in online education. Conversely, none of the variables showed a significant relationship with satisfaction levels in face-to-face education.

    Conclusion

     Both e-learning and face-to-face methods demonstrated relatively similar effects on students' learning outcomes. However, satisfaction levels with online education appear to be influenced by variables such as age, nativeness, and dormitory accommodation.

    Keywords: Face-To-Face Education, Electronic Learning, Physiology, Satisfaction, Learning, Students, Medicine}
  • Reza Asadzadeh, Aliashraf Mozafari, Fakhredin Taghinezhad, Fatemeh Pourrezagholi, Zahra Khalighi

    Aluminum Phosphide (ALP) is an effective, cheap, and highly toxic pesticide. ALP poisoning can have destructive effects on the human body, such as the heart, lungs, gastrointestinal tract, kidneys, and central nervous system, although all organs can be involved. We describe a 53-year-old Iranian Kurdish man with Hemolytic Uremic Syndrome (HUS) and Acute Kidney Injury (AKI). Supportive treatments such as hemodialysis and plasmapheresis were performed. After 23 days of hospitalization, the patient fully recovered and was discharged. Thrombotic microangiopathy such as HUS should be considered in patients with ALP toxicity that has a genetic defect in complement proteins. Combined use of hemodialysis and plasmapheresis improve outcomes in these patients.

    Keywords: Aluminum Phosphide Poisoning, Hemolytic Uremic Syndrome, Acute Kidney Injury}
  • Bahareh Ghiasi, Zahra Khalighi, Maryam Sadat Hashemi, Amin Mirzaei, Naser Abbasi, Aliashraf Mozafari *
    Background

    Methadone poisoning intentionally or accidentally leads to a high rate of treatment burden and cost and deaths. The evaluation of the factors affecting the severity of poisoning can reduce recovery time, costs, and potential risks.

    Objectives

    This study aimed to investigate the effect of intravenous vitamin C (ascorbic acid) administration on serum level and urinary excretion of methadone.

    Patients and Methods

    In this single-blind study, 54 patients who were diagnosed with methadone poisoning were divided into three groups. The two intervention groups received different doses of vitamin C, including 12 and 24 g, and the control group received normal saline. The serummethadone level and urine pH weremeasured at the time of arrival and 24 hours after admission. The data were analyzed using repeated measure analysis of variance (ANOVA) in STATA version 12.

    Results

    In this study, 18 patients were placed in each group. The three groups were not significantly different in basic variables, such as age, gender, and methadone dosage. Between and within-group comparison showed a significant decrease in the serum methadone levels over time after adjusting age, gender and methadone dosage (P < 0.05). Post-hoc analyses revealed a significant difference in methadone reduction between 12 g of vitamin C and control groups (P = 0.04), and there was no significant difference between the control and 24 g of vitamin C groups (P > 0.05). However, between and within-group comparisons showed no significant difference between the three groups in terms of urine pH (P > 0.05). In addition, interaction was observed between intervention and time on serum methadone levels (P < 0.001) and urine pH (P = 0.04) variables.

    Conclusions

    Consuming 12 g of vitamin C further reduced the serum methadone level in patients with methadone poisoning. There was no effect on methadone urinary excretion in patients.

    Keywords: Methadone, Poisoning, Urine, Vitamin C}
  • Bahareh Gheiasi, Fakhredin Taghinezhad, Darshik Kumar Patel, Ebrahim Salimi, Mashallah Babashahi, Aliashraf Mozafari
    Background

    COVID-19 usually complicates respiratory failure; microvascular, macrovascular, and renal complications are common. Both micro and macrovascular complications are associated with multi-organ dysfunction and in-hospital mortality. Thrombotic microangiopathy (TMA) causes microvascular thromboses associated with organ failure, including acute kidney injury (AKI).

    Materials and Methods

    This Retrospective Cohort study included 100 COVID-19 patients with thrombocytopenia, followed up in a university hospital’s intensive care unit (ICU). The primary endpoints were in-hospital mortality or discharge from the hospital and assessing the occurrence of TMA and AKI during the hospitalization. The effect of thrombotic microangiopathy and acute kidney injury on mortality was investigated using logistic regression models in Stata software version 12.1.

    Results

    The TMA and AKI were associated with in-hospital mortality in COVID-19 patients presenting with thrombocytopenia in multivariate regression analysis, adjusted for other variables. The effect of AKI on mortality was obtained (adjusted OR 4.09, 95% CI: 1.33–12.53, p = 0.01). Moreover, the odds of mortality due to TMA were ten-fold higher in the patients who had TMA than those who did not (adjusted OR 10.26, 95% CI: 1.26–83.76, p = 0.03).

    Conclusion

    We outlined TMA in COVID-19 patients, which could be responsible for kidney injury and mortality in critically COVID-19 patients.

    Keywords: SARS-CoV-2, COVID-19, Acute kidney injuries, Thromboses, Thrombocytopenia, Thromboticmicroangiopathy}
  • Nasim Bozorgi, Zolaykha Karamelahi, Iraj Ahmadi, Reza Valizadeh, Aylin Bozorgi, Aliashraf Mozafari *
    Background and aims

     The COVID-19 pandemic emerged in late 2019 with increased infection and mortality rates. Even with observing safety measures, medical staff have to deal with a high level of mental and physical pressure during an epidemic, and they might demonstrate diverse behaviors rooted in their experiences and emotions toward the situation. The paper examines different experiences and emotions of medical staff dealing with COVID-19 in Ilam, Iran.

    Methods

    A cross-sectional study was carried out with the participation of 200 care providers in 2020. Data was gathered using two questionnaires: the scale of positive and negative emotions (SPANE) and the positive and negative affect scale (PANAS). Data analyses were done in STATA12 using linear regression models.

    Results

    The mean score of positive emotion in ICU, general, maternity, and administrative wards in women were 32±6.23, 34.07±6.74, 35.35±9.24, and 35.61±6.91 respectively. The mean scores of Negative emotions in the Maternity ward and administrative departments were higher than in the ICU and CCU wards (P=0.05). The midwives’ mean negative emotions score was lower than the physician’s (P value<0.05). Average levels increased by about 4.41 scores in negative experiences for individuals with a work experience higher than 25 years compared to those with work experience less than ten years (P=0.03).

    Conclusion

    Factors such as type of work, workplace, and work experience that affect care providers’ positive and negative experiences and emotions should be considered in staffing arrangements and their expectations.

    Keywords: Emotions, Experience, COVID-19, Healthcare Worker}
  • فخرالدین تقی نژاد، نسرین بازگیر، امیر ادیبی، علی اشرف مظفری، ایوب رشیدی، یزدان رحیم بیگی، صیاد بسطامی نژاد *
    زمینه

    افسردگی یکی از اختلالات شایع در بیماران مبتلا به آرتریت روماتویید (RA) است که می تواند نتایج بالینی را در این بیماری تحت تاثیر قرار دهد. این مطالعه با هدف تعیین شیوع افسردگی و ارتباط آن با فعالیت بیماری در مبتلایان به RA صورت گرفت.

    روش کار

    در یک مطالعه مقطعی، 144 بیمار مبتلا به RA مراجعه کننده به کلینیک روماتولوژی بیمارستان شهید مصطفی خمینی (ره) ایلام از لحاظ معیار فعالیت بیماری و نیز وضعیت افسردگی بررسی شدند. داده های مربوط به فعالیت بیماری با استفاده از معاینه فیزیکی و تست آزمایشگاهی و بر اساس معیار نمره فعالیت بیماری (DASS28) و وضعیت افسردگی با پرسشنامه خوداظهاری بک جمع آوری و با مدل های رگرسیون خطی در نرم افزار STATA 14 آنالیز گردید.

    یافته ها

    شیوع کلی افسردگی در بیماران مورد مطالعه 61 درصد بود. بر اساس آنالیز مدل چند متغیره بیماران با فعالیت شدید بیماری در مقایسه با فعالیت خفیف بیماری، خطر بیشتری برای افسردگی داشتند. در بیماران با سطح شدید فعالیت بیماری نسبت به سطح فعالیتی خفیف و متوسط، نمره افسردگی 43/12 به طور معناداری بیشتر بود (P<0/001). مدل های پیش بین نشان دادند که در بیماران با فعالیت شدید بیماری، احتمال افسردگی با افزایش سن و مدت زمان ابتلا افزایش پیدا می کند.

    نتیجه گیری

    با توجه به رابطه افسردگی و افزایش فعالیت شدید بیماری RA، نیاز به غربالگری بیماران RA از نظر اختلال افسردگی و توجه مراقبت و درمان جسمی – روانی جامع جهت دستیابی به پیامدهای بالینی بهتر، ضروری به نظر می رسد. پیامدهای عملی. فعالیت شدید بیماری در RA ممکن است تحت تاثیر یک پدیده روان شناختی مانند افسردگی باشد. بنابراین وضعیت افسردگی باید به عنوان یکی از بیماری های موثر بر تشدید علایم RA مورد غربالگری و ارزیابی قرار گیرد. استفاده از رویکرد جامع نگر و چند رشته ای با کمک گرفتن از متخصصان روان پزشکی و روانشناسی در مدیریت بیماری RA پیشنهاد می گردد.

    کلید واژگان: آرتریت روماتوئید, افسردگی, فعالیت بیماری, شیوع}
    Fakhredin Taghinezhad, Nasrin Bazgir, Amir Adibi, Aliashraf Mozafari, Ayoub Rashidi, Yazdan Rahimbigi, Saiyad Bastaminejad *
    Background

    Depression is a common disorder in rheumatoid arthritis (RA) patients and can affect clinical outcomes. This study was conducted to determine the prevalence of depression and its relationship with disease activity in RA patients.

    Methods

    In this cross-sectional study, 144 patients with RA were recruited from the Rheumatology Outpatients Clinic, Mostafa Khomeini Hospital Ilam, and were examined for disease activity and depression symptoms. Disease activity was assessed by DAS28 using laboratory tests and physical examination. The Beck self-report questionnaire was used for measuring depression disorder. Data were analyzed using the linear regression models in STATA 14 software.

    Results

    The prevalence of depression in the sample was 61%. Multivariate analyses showed that patients with severe disease activity faced a significantly greater risk of depression compared to those with mild disease activity. Average levels increased by about 12.43 points in depression for patients with severe disease activity compared to those with mild disease activity. This association was statistically significant after adjusting for the model's other predictors (P<0.001). Furthermore, predicted models showed that the probability of depression increased with age and disease duration in patients with severe activity.

    Conclusion

    Considering the relationship between depression and severe RA disease activity, the need to screen RA patients in terms of depression disorder and pay attention to comprehensive mental and physical care and cure for better clinical outcomes seems necessary.

    Practical Implications

    Severe disease activity in RA may have been influenced by a psychological phenomenon such as depression; therefore, it was suggested that depression, as one of the diseases worsening the RA symptoms, should be screened and evaluated. It was also recommended that a comprehensive and multidisciplinary approach should be adopted by seeking assistance from psychiatric and psychological specialists in RA disease management.

    Keywords: Rheumatoid arthritis, Depression, Prevalence, Disease activity}
  • مهسا ریزه بندی، فرهاد محمدی *، علی اشرف مظفری، ایرج احمدی
    زمینه

    سال 2019 یک بیماری جدید به نام کووید-19 در شهر ووهان چین شناسایی شد. هرکسی ممکن است در هر سنی به این بیماری مبتلا و به شدت بیمار یا فوت شود. هدف از این مقاله تعیین عوامل موثر بر بستری شدن مجدد بیماران کرونایی بود.

    روش کار

    در این مطالعه نمونه ای به حجم 2411 نفر از بیماران کرونایی مراجعه کننده به بیمارستان شهید مصطفی خمینی شهر ایلام در نظر گرفته شد. متغیرهای جنس، سن، فوتی، شاخص توده بدنی، سردرد، استفراغ کردن، داشتن حالت سرما، سرفه کردن، درد عضله، داشتن بیماری زمینه ای، درجه تب، هموگلوبین، پلاکت خون، گلوکز و آنزیم های ALT، AST و LDH برای این مطالعه در نظر گرفته شد. برای پردازش مدل از رگرسیون لجستیک چندگانه در نرم افزار SPSS استفاده شد.

    یافته ها

    در این مطالعه بیشتر بیماران (5/54 درصد) مرد بودند. میانگین سنی در بیماران بستری مجدد، 63 سال بود. 23 درصد از بیماران که بستری مجدد شدند، فوت کردند. نتایج آزمون رگرسیون لجستیک نشان داد متغیرهای سن (OR=1.02, P=0.029)، جنس (OR=0.637, P=0.047)، داشتن بیماری زمینه ای (OR=2.36, P=<0.001)، هموگلوبین (OR=0.91, P=0.04)، تعداد پلاکت خون (OR=0.99, P<0.001)، استفراغ کردن یا به نوعی داشتن حالت تهوع (OR=0.48, P=0.03) و درد عضله (OR=0.61, P=0.04) از عوامل موثر شناسایی شدند.

    نتیجه گیری

    با توجه به بحث بستری مجدد بیماران کووید-19 در بیمارستان، داشتن بیماری همراه و سن بالا شانس بستری شدن مجدد را بالا می برد. در نهایت این پژوهش از لحاظ علمی تایید کرد که افزایش سن در کنار داشتن بیماری زمینه ای در بستری مجدد بیماران مبتلا به کووید-19 موثر است.

    پیامدهای عملی

    این مقاله در راستای پذیرش کامل درمان بیماران کووید-19 و در نتیجه عدم نیاز به بستری مجدد و جلوگیری از هزینه های اضافی درمان و اتلاف منابع است.

    کلید واژگان: بستری شدن, کووید-19, رگرسیون لجستیک چندگانه}
    Mahsa Rizehbandi, Farhad Mohammadi *, Ali Ashraf Mozafari, Iraj Ahmadi
    Background

    In 2019, a new disease called Covid-19 was identified in Wuhan, China. Anyone can get this disease at any age and become seriously ill, or even die from it. This study aimed to determine the factors affecting the re-admission of coronary patients.

    Methods

    In this study, 2411 Covid-19 patients referring to Shahid Mostafa Khomeini Hospital in Ilam, Iran were included. Variables such as gender, age, death, body mass index, headache, vomiting, having cold, cough, muscle pain, underlying disease, fever, hemoglobin, blood platelets, glucose as well as ALT, AST, and LDH enzymes were examined. SPSS software was used to fit the model of multiple logistic regressions in soft.

    Results

    Majority of the patients (54.5%) were males. The average age of readmitted patients was 63 years, and 23% of these patients died. The results of logistic regression test showed the variables of age (OR=1.02, P=0.029), sex (OR=0.637, P=0.047), underlying disease (OR=2.36, P=<0.001), hemoglobin (OR=0.91, P=0.04), blood platelet count (OR=0.99, P<0.001), vomiting or nausea (OR=0.48, P=0.03), and muscle pain (OR=0.61, P=0.04). Effective factors were also identified.

    Conclusion

    It was concluded that having a comorbid disease and old age increased the chances of re-admission. Moreover, it was scientifically confirmed that an increase in age along with having an underlying disease significantly contributed to re-admission of patients with Covid-19.

    Practical Implications

    The maximum effectiveness of the treatment of Covid-19 patients was confirmed by this study and, therefore, it was recommended that re-hospitalization should be avoided in order to avoid additional treatment costs and waste of resources.

    Keywords: Hospitalization, Covid-19, Multiple logistic regressions}
  • Samira Tardeh, Amir Adibi *, Ali Ashraf Mozafari

    An epidemic of infectious diseases such as COVID‑19 can affect mental health, which may be associated with suicidal behaviors. This study was conducted based on the systematic review and meta‑analysis methods for evaluating the prevalence of suicide ideation during COVID‑19. This study used Preferred Systematic Review Reporting System and Meta‑ Analysis guideline and valid keywords. The articles related to the prevalence of suicide ideation during COVID‑19 pandemic were obtained by searching among different databases including Scopus, Web of science, PubMed, ISC, Google scholar, SID, and Magiran. All of the articles published from the beginning of January 2020 to the end of May 2021 were reviewed. Among 478 articles screened, 377 articles were related to the studied topic, among which 38 articles were selected after assessing the title and abstract of which for reviewing the full text and finally 18 studies were included in the meta‑analysis. Based on the results, the prevalence of suicide ideation and attempt among all studies were equal to 13% (95% confidence interval = 0.11‑0.15, I2 = 99.7%, P = 0.00) and 1% (95% confidence interval = 0.00‑0.01, I2 = 95.5%, P = 0.00), respectively. Based on the results, the prevalence of suicide attempt and ideation is possible during the COVID‑19 pandemic. Therefore, health officials should pay attention to mental health issues in addition to the protective measures for preventing or reducing the infection with COVID‑19. The increase of psychological consequences is probably related to the effect of lifestyle changes which associates with the spread of the disease. In the current meta‑analysis performed, the prevalence of suicidal ideation and suicidal attempt was examined during the COVID‑19 pandemic period and compared to the previous period without COVID‑19. The effect of COVID‑19 on suicidal ideation and suicidal attempt has never been studied.

    Keywords: COVID‑19, suicidal attempt, suicidal ideation, suicidal thought}
  • فخرالدین تقی نژاد، نسرین بازگیر، امیر ادیبی، علی اشرف مظفری، ایوب رشیدی، یزدان رحیم بیگی، صیاد بسطامی نژاد *
    زمینه

     افسردگی یکی از اختلالات شایع در بیماران مبتلا به آرتریت روماتویید (RA) است که می‌تواند نتایج بالینی را در این بیماری تحت تاثیر قرار دهد. این مطالعه با هدف تعیین شیوع افسردگی و ارتباط آن با فعالیت بیماری در مبتلایان به RA صورت گرفت.

    روش کار

     در یک مطالعه مقطعی، 144 بیمار مبتلا به RA مراجعه‌کننده به کلینیک روماتولوژی بیمارستان شهید مصطفی خمینی (ره) ایلام از لحاظ معیار فعالیت بیماری و نیز وضعیت افسردگی بررسی شدند. داده‌های مربوط به فعالیت بیماری با استفاده از معاینه فیزیکی و تست آزمایشگاهی و بر اساس معیار نمره فعالیت بیماری (DASS28) و وضعیت افسردگی با پرسشنامه خوداظهاری بک جمع‌آوری و با مدل‌های رگرسیون خطی در نرم‌افزار STATA 14 آنالیز گردید.

    یافته‌ها

     شیوع کلی افسردگی در بیماران مورد مطالعه 61 درصد بود. بر اساس آنالیز مدل چند متغیره بیماران با فعالیت شدید بیماری در مقایسه با فعالیت خفیف بیماری، خطر بیشتری برای افسردگی داشتند. در بیماران با سطح شدید فعالیت بیماری نسبت به سطح فعالیتی خفیف و متوسط، نمره افسردگی 43/12 به‌طور معناداری بیشتر بود (P<0/001). مدل‌های پیش‌بین نشان دادند که در بیماران با فعالیت شدید بیماری، احتمال افسردگی با افزایش سن و مدت‌ زمان ابتلا افزایش پیدا می‌کند.

    نتیجه‌گیری

     با توجه به رابطه افسردگی و افزایش فعالیت شدید بیماری RA، نیاز به غربالگری بیماران RA از نظر اختلال افسردگی و توجه مراقبت و درمان جسمی – روانی جامع جهت دستیابی به پیامدهای بالینی بهتر، ضروری به نظر می‌رسد.

    پیامدهای‌عملی

    فعالیت شدید بیماری در RA ممکن است تحت تاثیر یک پدیده روان‌شناختی مانند افسردگی باشد. بنابراین وضعیت افسردگی باید به‌عنوان یکی از بیماری‌های موثر بر تشدید علایم RA مورد غربالگری و ارزیابی قرار گیرد. استفاده از رویکرد جامع‌نگر و چند رشته‌ای با کمک گرفتن از متخصصان روان‌پزشکی و روانشناسی در مدیریت بیماری RA پیشنهاد می‌گردد.

    کلید واژگان: آرتریت روماتوئید, افسردگی, فعالیت بیماری, شیوع}
    Fakhredin Taghinezhad, Nasrin Bazgir, Amir Adibi, Aliashraf Mozafari, Ayoub Rashidi, Yazdan Rahimbigi, Saiyad Bastaminejad *
    Background

     Depression is a common disorder in rheumatoid arthritis (RA) patients and can affect clinical outcomes. This study was conducted to determine the prevalence of depression and its relationship with disease activity in RA patients.

    Methods

    In this cross-sectional study, 144 patients with RA were recruited from the Rheumatology Outpatients Clinic, Mostafa Khomeini Hospital Ilam, and were examined for disease activity and depression symptoms. Disease activity was assessed by DAS28 using laboratory tests and physical examination. The Beck self-report questionnaire was used for measuring depression disorder. Data were analyzed using the linear regression models in STATA 14 software.

    Results

    The prevalence of depression in the sample was 61%. Multivariate analyses showed that patients with severe disease activity faced a significantly greater risk of depression compared to those with mild disease activity. Average levels increased by about 12.43 points in depression for patients with severe disease activity compared to those with mild disease activity. This association was statistically significant after adjusting for the model's other predictors (P<0.001). Furthermore, predicted models showed that the probability of depression increased with age and disease duration in patients with severe activity.

    Conclusion

    Considering the relationship between depression and severe RA disease activity, the need to screen RA patients in terms of depression disorder and pay attention to comprehensive mental and physical care and cure for better clinical outcomes seems necessary.

    Practical Implications

     Severe disease activity in RA may have been influenced by a psychological phenomenon such as depression; therefore, it was suggested that depression, as one of the diseases worsening the RA symptoms, should be screened and evaluated. It was also recommended that a comprehensive and multidisciplinary approach should be adopted by seeking assistance from psychiatric and psychological specialists in RA disease management.

    Keywords: Rheumatoid arthritis, Depression, Prevalence, Disease activity}
  • مهسا ریزه بندی، فرهاد محمدی *، علی اشرف مظفری، ایرج احمدی
    زمینه

     سال 2019 یک بیماری جدید به نام کووید-19 در شهر ووهان چین شناسایی شد. هرکسی ممکن است در هر سنی به این بیماری مبتلا و به شدت بیمار یا فوت شود. هدف از این مقاله تعیین عوامل موثر بر بستری شدن مجدد بیماران کرونایی بود.

    روش‌کار

     در این مطالعه نمونه ای به حجم 2411 نفر از بیماران کرونایی مراجعه کننده به بیمارستان شهید مصطفی خمینی شهر ایلام در نظر گرفته شد. متغیرهای جنس، سن، فوتی، شاخص توده بدنی، سردرد، استفراغ کردن، داشتن حالت سرما، سرفه کردن، درد عضله، داشتن بیماری زمینه ای، درجه تب، هموگلوبین، پلاکت خون، گلوکز و آنزیم های ALT، AST و LDH برای این مطالعه در نظر گرفته شد. برای پردازش مدل از رگرسیون لجستیک چندگانه در نرم افزار SPSS استفاده شد.

    یافته‌ها

     در این مطالعه بیشتر بیماران (5/54 درصد) مرد بودند. میانگین سنی در بیماران بستری مجدد، 63 سال بود. 23 درصد از بیماران که بستری مجدد شدند، فوت کردند. نتایج آزمون رگرسیون لجستیک نشان داد متغیرهای سن (OR=1.02, P=0.029)، جنس (OR=0.637, P=0.047)، داشتن بیماری زمینه ای (OR=2.36, P=<0.001)، هموگلوبین (OR=0.91, P=0.04)، تعداد پلاکت خون (OR=0.99, P<0.001)، استفراغ کردن یا به نوعی داشتن حالت تهوع (OR=0.48, P=0.03) و درد عضله (OR=0.61, P=0.04) از عوامل موثر شناسایی شدند.

    نتیجه‌گیری

     با توجه به بحث بستری مجدد بیماران کووید-19 در بیمارستان، داشتن بیماری همراه و سن بالا شانس بستری شدن مجدد را بالا می برد. در نهایت این پژوهش از لحاظ علمی تایید کرد که افزایش سن در کنار داشتن بیماری زمینه ای در بستری مجدد بیماران مبتلا به کووید-19 موثر است.

    پیامدهای عملی

     این مقاله در راستای پذیرش کامل درمان بیماران کووید-19 و در نتیجه عدم نیاز به بستری مجدد و جلوگیری از هزینه های اضافی درمان و اتلاف منابع است.

    کلید واژگان: بستری شدن, کووید-19, رگرسیون لجستیک چندگانه}
    Mahsa Rizehbandi, Farhad Mohammadi *, Ali Ashraf Mozafari, Iraj Ahmadi
    Background

     In 2019, a new disease called Covid-19 was identified in Wuhan, China. Anyone can get this disease at any age and become seriously ill, or even die from it. This study aimed to determine the factors affecting the re-admission of coronary patients.

    Methods

     In this study, 2411 Covid-19 patients referring to Shahid Mostafa Khomeini Hospital in Ilam, Iran were included. Variables such as gender, age, death, body mass index, headache, vomiting, having cold, cough, muscle pain, underlying disease, fever, hemoglobin, blood platelets, glucose as well as ALT, AST, and LDH enzymes were examined. SPSS software was used to fit the model of multiple logistic regressions in soft.

    Results

     Majority of the patients (54.5%) were males. The average age of readmitted patients was 63 years, and 23% of these patients died. The results of logistic regression test showed the variables of age (OR=1.02, P=0.029), sex (OR=0.637, P=0.047), underlying disease (OR=2.36, P=<0.001), hemoglobin (OR=0.91, P=0.04), blood platelet count (OR=0.99, P<0.001), vomiting or nausea (OR=0.48, P=0.03), and muscle pain (OR=0.61, P=0.04). Effective factors were also identified.

    Conclusion

     It was concluded that having a comorbid disease and old age increased the chances of re-admission. Moreover, it was scientifically confirmed that an increase in age along with having an underlying disease significantly contributed to re-admission of patients with Covid-19.

    Practical Implications

     The maximum effectiveness of the treatment of Covid-19 patients was confirmed by this study and, therefore, it was recommended that re-hospitalization should be avoided in order to avoid additional treatment costs and waste of resources.

    Keywords: Hospitalization, Covid-19, Multiple logistic regressions}
  • محمدرضا کفاشیان، مریم باقری، علی اشرف مظفری، مریم کریمیان، سجاد سالاری*
    مقدمه

     نتایج متناقضی درباره پیش‌آگهی کووید-19 در بیماران با کم‌کاری تیرویید وجود دارد. مطالعه حاضر با هدف بررسی شدت علایم و مولفه‌های خونی در بیماران مبتلا به کم‌کاری تیرویید و کووید-19 انجام شد.

    مواد و روش ها

     100 بیمار کووید-19 (50 بیمار با سابقه تیرویید [هیپوتیرویید] و 50 بیمار بدون اختلال تیرویید [یوتیرویید])، در مطالعه حاضر بررسی گردیدند. مشخصات دموگرافیک و بالینی بیماران از رجیستری کووید-19 در بیمارستان شهید مصطفی خمینی جمع‌آوری شد. همه بیماران بین اسفند 1398 تا آذر 1399 بستری و تحت درمان قرار گرفته بودند. تعداد روزهای بستری در بیمارستان، میزان پذیرش در بخش مراقبت‌های ویژه و فاکتورهای خونی ارزیابی گردیدند.

    یافته‌ ها: 

    مدت‌زمان بستری در بیماران مبتلا به کووید-19 هیپوتیرویید به‌طور معنی‌داری، طولانی‌تر از گروه یوتیرویید بود (P=0.009)، این در حالی است که مولفه‌های خونی شامل تعداد گلبول‌های قرمز (RBC)، سطح هموگلوبین و میزان هماتوکریت در گروه هیپوتیرویید کمتر از گروه یوتیرویید (به‌ترتیب P=0.001، P=0.003 و P=0.003) و تعداد گلبول‌های سفید (WBCs) و شاخص‌های التهابی شامل سرعت رسوب گلبول قرمز (ESR) و سطح پروتیین واکنشی C (CRP) در هر دو گروه یکسان بود.

    بحث و نتیجه‌گیری:

    بیماری زمینه‌ای کم‌کاری تیرویید تاثیر معنی‌داری بر شدت التهاب ناشی از کروناویروس نداشت؛ اما سبب طولانی شدن مدت‌زمان بستری در این بیماران می‌شد. کم‌خونی که مشکل رایجی در بیماران کم‌کاری تیرویید است، ممکن است علت طولانی شدن مدت‌زمان بستری در این بیماران باشد.

    کلید واژگان: زمان بستری, عامل های التهابی, کم کاری تیروئید, کووید-19, فاکتورهای خونی}
    Mohamadreza Kaffashian, Maryam Bagheri, Ali Ashraf Mozafari, Maryam Karimian, Sajjad Salari *
    Introduction

     There is inconsistent data regarding COVID-19 prognosis in patients with background hypothyroid disorder. The present study aimed to evaluate the severity of symptoms and blood parameters in COVID-19 patients with hypothyroidism.

    Material & Methods

     This study investigated 100 COVID-19 patients (50 individuals with a history of hypothyroidism and 50 patients without thyroid disorder [euthyroid]). Demographic and clinical characteristics were collected from the COVID-19 registry database in Shahid Mustafa Khomeini Hospital. All patients were admitted and treated between March and December 2020. Hospitalization duration, the ICU admissions rate, and blood laboratory tests were evaluated in this study.

    Findings

     Hospitalization period was significantly longer in the hypothyroid group, compared to the euthyroid group (P=0.009). The number of red blood cells (RBCs), hemoglobin level, and hematocrit percentage were lower in the hypothyroid group (P=0.001, P=0.003, and P=0.003, respectively). Nevertheless, the number of white blood cells (WBCs) and inflammatory indicators, including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were the same in both groups.

    Discussion &  Conclusion

     Although background hypothyroidism had no significant effect on inflammation severity caused by COVID-19; however; it extended hospital stay in these patients. Anemia, a common problem in hypothyroidism, may explain longer hospitalization in hypothyroid COVID-19 patients.

    Keywords: Blood factors, COVID-19, Hospitalization, Hypothyroidism, Inflammatory factors}
  • Nasrin Bazgir, Fakhredin Taghinezhad *, Hassan Nourmohammadi, Golnaz Azami, Iraj Ahmadi, Aliashraf Mozafari **
    Background

    Patients with cancer are potentially vulnerable to COVID-19 infection due to the immune-compromised state of cancer or its treatment complications.

    Objectives

    This study compared the COVID-19 mortality rate in cancer patients with and without a history of chemotherapy.

    Methods

    This registry-based cohort study launched from March 2020 to March 2021 contains 2350 records in which 64 COVID-19 patients with cancer were included, of which 27 patients underwent the chemotherapy plan within eight weeks before confirmed COVID-19. In addition, age and sex were matched in patients without a history of cancer as a control group. Two groups of cancer patients with and without a history of chemotherapy compared to the control group using cox proportional hazard regression models in Stata.10 software.

    Results

    Patients with cancer had a higher hazard for in-hospital mortality from COVID-19 infection (adjusted HR; 2.27, 95% CI: 1.25 - 4.13, P = 0.007) after adjusting for age, sex, body mass index (BMI), and co-morbidities. Our result showed no significant association between chemotherapy and control groups (adjusted HR; 1.65, 95% CI: 0.60 - 4.56, P = 0.33).

    Conclusions

    Patients with cancer faced a risk of mortality from COVID-19 two times higher than those without cancer. However, chemotherapy did not increase the mortality following COVID-19 infection.

    Keywords: Drug Therapy, COVID-19, SARS-CoV-2 Infection, Neoplasm, Chemotherapy}
  • Reza Asadzadeh, Aliashraf Mozafari, Elham Shafiei, Mohammadreza Kaffashian, Iraj Ahmadi, Mohammadzaman Darvish, Saiyad Bastaminejad*
    Background

    Anemia often worsens the severity of respiratory illnesses, and few studies have so far elucidated the impact of anemia on COVID-19 infection. This study aimed to evaluate the effect of anemia at admission on the overall survival of COVID-19 patients using AFT models.

    Methods

    This registry-based, single-center retrospective cohort study was conducted in a university hospital in Ilam, the southwest of Iran, between March 2020 and September 2021. AFT models were applied to set the data of 2,441 COVID-19 patients. Performance of AFT models was assessed using AIC and Cox-Snell residual. On-admission anemia was defined as Hb concentration <120 g/l in men, <110 g/l in women, and <100 g/l in pregnant women.

    Results

    The median in-hospital survival times for anemic and non-anemic patients were 27 and 31 days, respectively. Based on the AIC and Cox-Snell residual graph, the Weibull model had the lowest AIC and it was the best fitted model to the data set among AFT models. In the adjusted model, the results of the Weibull model suggested that the anemia (adjusted TR: 1.04; 95% CI: 1.00-1.08; p = 0.03) was the accelerated factor for progression to death in COVID-19 patients. Each unit of increase in hemoglobin in COVID-19 patients enhanced the survival rate by 4%.

    Conclusion

    Anemia is an independent risk factor associated with the risk of mortality from COVID-19 infection. Therefore, healthcare professionals should be more sensitive to the Hb level of COVID-19 patients upon admission.

    Keywords: Anemia, COVID-19, Risk factors, Mortality, Survival}
  • Mohammadreza Kaffashian, Marzieh Hadavi, Fakhredin Taghinezhad, Iraj Ahmadi, Samaneh Tahmasebi Ghorabi, Amin Khalafzadeh, Aliashraf Mozafari*
    Background and Objective

     Individuals with opioid use disorder are a marginalized population in any society. They commonly have a weaker immune system, greater stress vulnerability, poorer health, more high-risk behaviors, and less access to healthcare services compared to the general population, which can expose them to a risk of severe COVID-19 complications. This study aimed to evaluate the effects of opioid use disorder on mortality in patients with SARS-CoV-2.

    Materials and Methods

     This registry-based retrospective cohort study was conducted on 2362 consecutive inpatients with a confirmed diagnosis of SARS-CoV-2 between March 5, 2020 and March 21, 2021, presenting to a university hospital in Ilam in the southwest of Iran. Forty-five patients with opioid use disorder were identified in this study and matched to 100 patients without opium addiction. All patients with a history of opium addiction were included in the study group, and age- and sex-matched patients without opioid use disorder were randomly recruited as the controls. After adjusting for the effects of age and comorbidities, data were analyzed in STATA version 10, using logistic regression models.

    Results

     The mortality of patients with opioid use disorder increased following COVID-19 (adjusted OR: 6.59; 95% CI: 1.84–23.59; P=0.004). Hypertension (adjusted OR: 8.17; 95% CI: 2.21–30.15; P=0.002) and advancing age (OR: 1.06; 95% CI: 1.01–1.11; P=0.01) were significantly associated with increased COVID-19 mortality.

    Conclusion

     Based on the present findings, opioid use disorder is a possible risk factor for mortality following COVID-19. The findings of the present study can be applied in the implementation of preventive measures and policies and prioritization of COVID-19 vaccination. However, further relevant research is recommended.

    Keywords: COVID-19, Opioid use disorder, Opioids, Mortality}
  • Marzieh Hadavi, Fakhredin Taghinezhad, Elham Shafiei, Sharif Hama Babakr, Saiyad Bastaminejad, Mohammadreza Kaffashian, Iraj Ahmadi, Aliashraf Mozafari
    Background

    Electrolyte imbalances are common in COVID-19 infection and are associated with poor outcomes in hospitalized patients.

    Objectives

    This study examined whether serum phosphate imbalances at admission are associated with mortality in hospitalized COVID-19 patients.

    Methods

    In this registry-based single-center retrospective cohort study, 1349 inpatients with COVID-19 were included from March 2020 to March 2021 in an academic hospital in Ilam (southwest Iran). The Cox proportional hazard (PH) regression model was applied to the data set of COVID-19.

    Results

    The in-hospital median survival time for patients with low, normal, and high serum phosphate levels was 14, 25, and 8 days, respectively. In a multivariate model, adjusted for the other variables, patients with hypophosphatemia (adjusted hazard ratio [HR], 2.53; 95% CI, 1.15 - 5.58; P = 0.02) and hyperphosphatemia (adjusted HR, 1.77; 95% CI, 1.00 - 3.14; P = 0.05) had an increased mortality hazard compared with those who had normal levels of serum phosphate.

    Conclusions

    Our results demonstrate a strong effect of hypophosphatemia and hyperphosphatemia with increased in-hospital mortality in COVID-19 patients. Intensive medical care and more attention must be paid to COVID-19 patients with serum phosphate imbalances at admission.

    Keywords: In-Hospital Mortality, COVID-19, SARS-CoV-2, Hypophosphatemia, Hyperphosphatemia}
  • Bahareh Gheiasi, Marzieh Hadavi, Reza Asadzadeh, Fakhredin Taghinezhad, Reza Mahmodzadeh, Ali Ashraf Mozafari
    Background

    Decrease in Bone Mineral Density (BMD) is one of the complications of kidney transplantation in which many factors are involved. The results of studies are different and contradictory.

    Objective

    to investigate the prevalence and related factors influencing BMD in renal transplant recipients.

    Methods

    all kidney recipients (69 patients) referring to the Shahid Mostafa Khomeini Hospital, Ilam, Southwest of Iran, were included between 2016 and 2018. BMD of the lumbar spine and femoral neck was performed using dual-energy X-ray absorptiometry (DEXA). According to Z- score and T- score, patients were divided into two groups: fewer than 50 and over 50 age years. All demographic, background variables and laboratory parameters were evaluated. Descriptive statistics and Binary and multinomial logistic regression were used to analyze.

    Results

    The overall prevalence of osteoporosis in the femur and lumbar spine was 38% and 32%, respectively. In patients under 50 years, Osteoporosis in the femur showed a significant relationship with vitamin D level and gender. In patients over 50 years, increased age and length of prednisolone consumption were associated with an increased risk of osteoporosis and osteopenia in the femoral neck (P <0.05). Moreover, the length of use of prednisolone was associated with osteoporosis in the lumbar spine (RRR=1.02; p <0.05).

    Conclusion

    various factors such as prednisolone consumption affect BMD reduction in renal transplant recipients. Regular monitoring of BMD, reducing prednisolone dose as much as possible, training on effective supplements, and other preventive and supportive measures can be helpful and necessary.

    Keywords: Bone mineral density, Renal transplantation, Osteoporosis, Osteopenia, Prednisolone}
  • Kourosh Sayehmiri, Ali-Ashraf Mozafari, Reza Valizadeh, Norollah Yadeghari, Marzieh Rostamkhani, Ali Khorshidi, Ali-Ashraf Aivazi, Maryam Deldar *
    Objective

    Suicide is one of the most important health problems in the world. Financial, academic, social, and environmental difficulties along with genetic, physical, and mental disorders affect suicide attempts. This study aimed to find risk factors for completed suicide in Ilam province according to the suicide registry in Ilam province.

    Method

    This was a prospective study and was performed based on suicide case registration data, pre-determined checklist data, and death registration data in Ilam province from March 2019 to September 2020. Logistic regression models and the Chi-square test were used to determine the relationship between completed suicide and its risk factors.

    Results

    Among 1,410 attempted suicides, 66 (4.7 %) were executed. Rate of completed suicides was higher in men (6.5%) compared to women (4.5%), (p = 0.005), age groups over 65 years (P < 0.001), retirees and farmers (P = 0.009), illiterate people (P < 0.001), villagers (P = 0.02), people motivated due to physical problems (P = 0.016), suicide by physical methods (P < 0.001) and self-immolation (P < 0.001). Logistic regression showed that incidence of completed suicide was significantly higher in the age group over 65 years, illiterate people, people using physical methods, villagers, and men. Multivariate logistic regression also showed that men and individuals using physical methods of suicide were significantly more successful in suicide.

    Conclusion

    Men, the elderly, illiterates, villagers, and people who used physical suicide methods were in high-risk groups. Despite lower prevalence of suicide, a higher rate of completed suicide was demonstrated. To decrease completed suicide rates, we must pay attention to these groups.

    Keywords: Completed Suicide, Prevalence, Risk Factors, Suicide Attempt}
  • نسرین بازگیر، رامین کرمی، زهرا خلیقی، علی اشرف مظفری، ایرج احمدی، الهام شفیعی، مریم ملکی*
    سابقه و هدف

    آرتریت روماتویید (RA) یک بیماری خود ایمنی التهابی مزمن است که مشخصه آن درگیری لایه سینوویال، التهاب و تخریب مفصل می باشد و عدم کنترل مناسب آن باعث تخریب غضروف، استخوان، لیگامان و تاندون ها می شود و در برخی موارد منجر به ناتوانی افراد مبتلا می شود. این مطالعه با هدف بررسی نقش احتمالی نسبت نوتروفیل به لنفوسیت (NLR) به عنوان یک مارکر التهابی در تعیین شدت RA (Disease Activity Score 28 [DAS28]) انجام شد.

    مواد و روش ها

    50 بیمار مبتلا به RA مراجعه کننده به کلینیک روماتولوژی بیمارستان شهید مصطفی خمینی شهر ایلام از نظر فعالیت بیماری مورد معاینه (فیزیکی و بررسی تست های آزمایشگاهی) قرار گرفتند. NLR و شدت فعالیت بیماری براساس فرمولDAS28، محاسبه شد.

    یافته ها

     34درصد از بیماران دارای 2/6< DAS28 در دسته remission و 66درصد با 2/6 > DAS28 در دسته بندی خفیف و متوسط قرار گرفتند. 86درصد از بیماران زن و 14درصد آنان مرد بودند. میانگین سن بیماران در گروه خفیف و متوسط51/30 و در گروه remission،36/82 سال بود. میانگین NLR در گروه remission، 1.80 و در گروه خفیف و متوسط 1/93 بود و ارتباط معنی داری بین NLR در دو گروه مورد مطالعه DAS28 وجود نداشت (0/99 =P). بین DAS28 و میزان رسوب گلبول قرمز (ESR) رابطه معنی داری وجود داشت (0/02=P) و رابطه ضعیفی بین DAS28 با سن، جنس و دارو وجود داشت (0/1≤P).

    استنتاج

    بر اساس نتایج، در بیماران RA با 3/2DAS28<  احتمالا ESR، نسبت به NLR، می تواند یک عامل پیش آگهی برای تعیین سطح فعالیت بیماری باشد.

    کلید واژگان: آرتریت روماتوئید, DAS28, نسبت نوتروفیل به لنفوسیت}
    Nasrin Bazgir, Ramin Karami, Zahra Khalighi, Ali Ashraf Mozafari, Iraj Ahmadi, Elham Shafeie, Maryam Maleki*
    Background and purpose

    Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by synovitis, inflammation, and joint destruction that if not well controlled can destroy cartilage, bone, ligaments and tendons, and in some cases cause disability. The aim of this study was to evaluate the possible role of the ratio of neutrophil-lymphocyte (NLR) as an inflammatory marker in determining the severity of RA (Disease Activity Score 28 [DAS28]).

    Materials and methods

    Fifty patients with RA attending the rheumatology clinic in Ilam Shahid Mostafa Khomeini Hospital, Iran, were examined for disease activity using physical and laboratory tests. NLR and disease severity were determined based on DAS28.

    Results

    The disease activity, including remission and mild/moderate were seen in 34% (DAS28<2.6) and 66% (DAS28 2.6), respectively. The patients were 86% women and 14% men. Mean ages of patients with mild/moderate and remission RA were 51.30 and 36.82 years, respectively. The mean NLR was 1.80 in patients with remission RA and 1.93 in those with mild/moderate RA and no significant relationship was found in NLR between these two groups (P=0.99). There was a significant relationship between DAS28 and erythrocyte sedimentation rate (ESR) (P=0.02), and a weak relationship between DAS28 and age, gender, and medication (P≥0.1).

    Conclusion

    According to the results, perhaps ESR rather than NLR could be a prognostic factor for determining disease activity levels in RA patients with DAS28 <3.2.

    Keywords: rheumatoid arthritis, DAS28, neutrophil to lymphocyte ratio}
  • Reza Asadzadeh, Zahra Khalighi, Nahid Mamizadeh, Marzieh Hadavi, Abas Ghaysouri, Aliashraf Mozafari *

    Context: 

    Acetylcysteine is an effective treatment for acetaminophen poisoning. The preparation and dose calculation of acetylcysteine is associated with medical errors. The prevalence of this error is 34% globally.

    Case report:

     A 15-year-old girl took an overdose of acetaminophen in a suicide attempt. Acetylcysteine intravenous was ordered. Due to the medication error by the nurse, she received a 10-fold overdose of intravenous acetylcysteine in both initial loading dose and maintenance dose, at first day. On the second day, the patient showed abdominal pain, nausea, vomiting, and elevated liver enzymes. Her hemoglobin, hematocrit, and platelet quickly decreased. Subsequently, she developed oliguria, anuria, and rising serum creatinine levels. The patient was diagnosed with uremic hemolytic syndrome. She underwent hemodialysis and was treated with plasmapheresis, blood transfusions, and platelets.

    Discussion

     The effects of acetaminophen poisoning and acetylcysteine overdose may be much more severe and have a greater impact on patient survival than each poisoning alone. Timely and accurate treatment measures can help prevent long-term side effects.

    Keywords: Medication Error, Renal Failure, Acetylcysteine}
  • علی اشرف مظفری، امیر ادیبی، الهام شفیعی، علی صاحبی*

    بروز رفتار خودکشی در کودکان زیر 10 سال یک اعلان خطر و موضوعی نگران کننده است. این پدیده می تواند یک شاخص مهم برای ارزیابی وضعیت روانی افراد در جامعه باشد. این مطالعه یک پسر بچه 8ساله را گزارش می کند که سابقه سه بار اقدام به خودکشی به روش حلق آویز داشته است. مشاوره روان پزشکی نشان داد که این کودک افسردگی پنهان دارد. نتایج ارزیابی رفتار کودک توسط والدین از طریق چک لیست رفتاری کودک نشان داد که این کودک بالاترین نمرات را به ترتیب در حیطه های اختلال رفتاری پرخاشگرانه، مشکلات توجه، رفتار قانون شکنی و اختلال افسردگی اضطراب دارد. عدم توجه والدین در برآوردن نیازهای گوناگون کودکان و نبود محیط پرورشی و حمایتی ممکن است منجر به بروز اختلالات رفتاری عاطفی در کودک شده و زمینه را برای بروز رفتارهای خطرناکی مانند اقدام به خودکشی در کودک فراهم کند.

    کلید واژگان: اقدام به خودکشی, اختلال افسردگی اساسی, رفتار کودک, غفلت از کودک}
    Ali Ashraf Mozafari, Amir Adibi, Elham Shafiei, Ali Sahebi*
    Objectives

     Suicidal behavior in children under 10 years of age is a warning and a matter of concern. It can be an important indicator for evaluating the mental health of individuals in the community. 

    Case Report

    This study reported an 8-year-old boy who had three failed suicide attempts by hanging. The psychiatric assessment revealed that he had major depressive disorder which had not been diagnosed.

    Conclusion

     Evaluation of his behavior by using the Child Behavior Checklist completed by his parents showed that he had the highest scores in aggressive behavior, attention problems, rule-breaking behavior, and anxious/depressed subscales. Lack of parental attention to meeting the needs and creating a supportive environment may have led to behavioral-emotional disorders and risky behaviors such as suicide in the boy.

    Keywords: Suicide attempt, Major depressive disorder, Child behavior, Child neglect}
  • Aliashraf Mozafari, Amir Adibi, Tayebe Jamshidbeigi, Elham Shafiei, Ali Sahebi*

    Postpartum depression (PPD) is a mood disorder that can affect women after childbirth and this disorder can strike fathers as well as mothers.  The study reports a 28-year-old man who attempted suicide three times following his wife delivery and newborn baby boy. Psychiatric assessment showed that the man revealed major depression following childbirth. So effective mental disorders screening and health care services must be provided for fathers as well as mothers and children.

    Keywords: Postpartum depression, Attempted suicide, Childbirth, Mental disorder, Hanging}
  • Katayoun JAHANGIRI, Kosar YOUSEFI, Aliashraf MOZAFARI, Ali SAHEBI*
    Background

    Disasters have many health consequences such as suicide ideation as one of the relatively common psychological consequences after natural disasters, especially earthquakes. This study aimed to determine the prevalence of post-earthquake suicidal ideation in affected people.

    Methods

    Related keywords of this systematic review and meta-analysis in English and their Persian equivalents were searched in the data resources including Google Scholar, SID, Magiran, Scopus, PubMed, and Web of Science from Jan 2014 to May 2019. The STROBE checklist was used to evaluate the quality of the articles. The I2 index was used to determine the heterogeneity and the random-effects model was used in meta-analysis. Statistical analysis was conducted in the STATA software version 14.

    Results

    Overall, 14347 subjects including 6662 males and 7715 females with the mean age of 23.88 ± 15.81yr old were assessed. The prevalence of post-earthquake suicidal ideation was 20.34% (95% CI: 13.60-27.08, P<0.001, I2=99.1). The prevalence of suicidal ideation showed a decreasing trend based on the year of the study and the duration of post-earthquake follow-up.

    Conclusion

    Although the prevalence of post-earthquake suicidal ideation showed a decreasing trend, the probability of incidence of these thoughts in the long-term is still noticeable. Therefore, implementing a surveillance system is recommended to monitor the mental health status of earthquakes survivors for the possibility of suicidal thoughts in the short and long term recovery phase.

    Keywords: Suicidal ideation, Suicidal thought, Natural disasters, Earthquakes, Meta-analysis, Systematic review}
  • Amir Adibi, Aliashraf Mozafari, Golnaz Azami, Tayebe Jamshidbeigi, Ali Sahebi*
  • Elham Shafiei, Arash Nademi, Ali Ashraf Mozafari, Elham Bastani, Taleb Kokhazadeh, Kosar Yousefi, Ali Sahebi *
    Background

    The incidence of limb fractures in children depends on environmental factors and socioeconomic backgrounds.

    Objectives

    This study aimed to evaluate the epidemiology of limb fractures in 1 to 15-year-old children in Ilam City, Iran.

    Methods

    This retrospective study enrolled all children aged 15 and below admitted to the Emam Khomeini Hospital of the Ilam University of Medical Sciences between July 2012 and March 2018. Data including age, sex, injury mechanism, and injured organs were recorded in SPSS software and analyzed using a chi-square test.

    Results

    Out of 4877 children, 74.3% were boys, and 25.7% were girls, with the men to women ratio of 2.87 and the mean age of 9.10 ± 4.3 years. Elbow and forearm with 39.35% and leg with 21.61% were the most common sites of fractures. Home, street, and sports fields were the commonplaces of injury with 50.7%, 28.3%, and 7.2%, respectively. The age range of 8 - 15 years, with 3693 cases (75.72%) was the most vulnerable age group. Fractures occurred mostly in spring and summer and less frequently in the other seasons.

    Conclusions

    Specific attention should be paid to the home environment and its safety for controlling injuries in preschool children. This includes increasing parents’ knowledge of preventive measures. Moreover, improving the physical condition of pavements and crosswalks in the streets is necessary for the prevention of injuries.

    Keywords: Pediatrics, Epidemiology, Fracture}
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