amir ghorbani

Knowledge exchange between university and industry is considered a vital phenomenon to promote innovation in industries. despite the apparent benefits for the industry and the university, its success cannot be guaranteed, and many university-industry collaborations face various challenges. In other words, it can be stated that the formation of this relationship over time is not fundamentally based and its direction is not purposeful. Despite the studies conducted in the field of industry-university relationships, more needs to be addressed explicitly to the challenges of the university side in the relationship between industry and university. Therefore, the purpose of this research is to present the framework of the university's challenges in the relationship between the university and the industry. This research is applied type, its strategy is a qualitative study, and in terms of its objective, it is descriptive. The data required to achieve the research goal has been obtained using primary and secondary data from December 2021 to April 2022. By using secondary data, the dimensions of the challenges of the university side in the relationship between the industry and the university in 5 categories, including 1) policy-making and governance; 2) administrative and executive; 3) intermediary institutions; 4) intellectual and financial ownership; 5) cultural identification and as a conceptual framework for identifying challenges in this research. Then, 25 experts from universities, research institutes, and political institutions who are familiar with industry-university relationship issues were interviewed to identify examples of challenges. Finally, through the analysis of the content of the conducted interviews, 22 challenges corresponding to each of the dimensions were identified.

The Ministry of Science, Research and Technology and its subordinate actors, as one of the crucial sub-systems in the national innovation system, play a vital role in the structure, functions, and performance of the national innovation system. In this regard, the current research was conducted with the aim of identifying and prioritizing the functions and sub-functions of the Ministry of Science, Research, and Technology in the national innovation system. In terms of methodology, this research is mixed research that has benefited from thematic analysis in the qualitative part and importance-performance analysis in the quantitative part. In the qualitative part, the review of international documents, laws and regulations, and upstream documents and the analysis of data related to focus groups with different stakeholders led to the preparation of a list of 60 sub-functions under the 7 main functions of the Ministry of Science, Research, and Technology. Then, to achieve the priority sub-functions of the Ministry of Science, Research, and Technology, the importance-performance questionnaire was sent to universities, research institutes, and science and technology parks, and 33 completed questionnaires were collected. Based on the importance-performance analysis, 40 sub-functions were selected as priority sub-functions (low performance and high importance) of the Ministry of Science, Research and Technology. Identifying the priority sub-functions of the Ministry of Science, Research and Technology can be a basis for a more accurate functional and performance analysis and formulation of policies and programs in order to strengthen the role of this Ministry in the national innovation system.

This paper aims to provide a policy mix to support the socio-economic effectiveness and applicability of humanities.While gaining scientific authority within humanities disciplines and championing their role in advancing civilization have certainly pervaded policy discourse in recent years, the observation highlights a shortcoming - namely, the lack of a cohesive policy mix to reliably foster the socio-economic effectiveness and applicability of humanities. Literature shows that the socio-economic effectiveness and applicability of humanities have a rich historical trajectory. Its origins lie in addressing ethical and legal concerns, which then evolved to encompass the establishment of educational and research institutions focused on scientific concepts. Subsequently, humanities began yielding tangible economic and social benefits for industries and society. However, when comparing the socio-economic effectiveness and applicability of humanities to fundamental and engineering sciences, a tailored policy framework is indispensable to acknowledge the unique position of humanities within government structures. To shed light on this matter, we conducted an examination of nine esteemed international humanities institutions, including the National Endowment for the Humanities (NEH), National Institute for the Humanities and Social Sciences (NIHSS), Social Sciences and Humanities Research Council (SSHRC), European Social Fund (ESF), Economic and Social Research Council (ESRC), Arts and Humanities Research Council (AHRC), Office of Social Innovation and Civic Participation (OSICP), Indian Council of Social Science Research (ICSSR), and Arab Council for the Social Science (ACSS). From this comprehensive analysis, we derived an initial framework aimed at enhancing the socio-economic effectiveness and applicability of humanities.We employed a qualitative methodology to contextualize the initial framework within the Iranian context. From January to May 2023, we conducted interviews with 25 experts utilizing the snowball technique, ensuring a diverse range of perspectives. By engaging experts affiliated with various organizations and institutions, e.g., the Ministry of Science, Research, and Technology, the Supreme Council of the Cultural Revolution, Vice-Presidency for Science, Technology, and Knowledge-Based Economy, the Ministry of Culture, the Ministry of Labour and Social Affairs, and Academy of Sciences of Iran, we sought to minimize bias and capture a comprehensive understanding of the subject matter. To analyze the gathered data, we employed the abductive content analysis approach—an esteemed qualitative research method renowned for its ability to unveil patterns, themes, and inherent meanings within textual data. This meticulous, analytical process allowed us to derive valuable insights specific to the Iranian context.Based on our findings, we suggested a set of 18 supports under 5 policy mix to foster the socio-economic effectiveness and applicability of humanities. The proposed policy mix, proposed by the authors, encompasses the following.- Supporting applied and developmental research: By allocating resources towards applied research initiatives, we aim to enhance the practical relevance of humanities. This approach ensures that research outcomes contribute directly to societal and economic needs.- Supporting product and service development: We foster their application in real-world contexts by facilitating the development of innovative products and services rooted in humanities. This enables translating theoretical knowledge into tangible solutions for industries and society.- Supporting empowerment and specialized skill enhancement for skilled workers: Recognizing the pivotal role of skilled professionals in driving socio-economic progress, we advocate for initiatives that empower and enhance the expertise of individuals working within humanities-related fields. This support ensures the cultivation of specialized skills needed to address contemporary challenges.- Supporting innovative cultural and social services and centers: By investing in the establishment and sustenance of cultural and social service centers, we create spaces that promote creativity, innovation, and community engagement. This support enables exploring novel ways in which humanities can positively impact society.- Supporting infrastructure development and networking: Recognizing the significance of robust infrastructure and networking opportunities, we emphasize the need for investments in this realm. By fostering a supportive ecosystem, we enable effective collaboration, knowledge sharing, and resource utilization within the humanities community.The policy mix and support measures proposed in this study hold both practical and theoretical implications. They provide a roadmap for directing mechanisms that effectively promote the socio-economic effectiveness and applicability of humanities, ensuring their continued relevance and impact in contemporary society.

Avibacterium paragallinarum causes infectious coryza that is an important disease of chickens associated with an acute upper respiratory infection, growth retardation, marked drop in egg production, reduced hatchability, and increased number of culls. Infectious coryza has been reported from all around the world including Iran where chickens are raised.

This study was conducted to isolate Avibacterium paragallinarum from the suspected cases of infectious coryza in the backyard and commercial layer chickens in three provinces of Tehran, Alborz, and Qazvin in Iran, to characterize the isolates by molecular methods and to determine their antimicrobial susceptibility profile.

Swab samples from eye secretions and mouth cavity were provided from five commercial laying farms (25 samples) and backyard chickens (20 samples) suspected of infectious coryza in Tehran, Alborz, and Qazvin provinces of Iran. Standard bacteriological and biochemical procedures were performed for the isolation and identification of Av. paragallinarum. The antimicrobial susceptibility of the recovered isolates was determined by the agar disk diffusion method. HPG-2 PCR was used to confirm Av. paragallinarum using the specific primers of N1 and R1, resulting in a 500 bp amplicon. PCR-amplified hmtp210 gene with the amplicon size of 1.6 kb was subjected to sequencing with the standard Sanger sequencing method and phylogenetically analyzed.

Three Av. paragallinarum isolates were obtained from all the cultured samples. Antimicrobial sensi-tivity test revealed that all three isolates were resistant to amoxicillin, oxytetracycline, streptomycin, ampicillin, and colistin while they were susceptible to cephalexin, ceftriaxone, florfenicol, gentamicin, linco-spectin, neomycin, and doxycycline. In phylogenetic analysis, two different genotypes of Av. paragallinarum were found.

In this study, Av. paragallinarum isolates recovered from layer flocks were genotypically closely related to the strains from serovar C while the isolate recovered from backyard chickens was closely related to serovar B strains. Our results showed that the antimicrobial susceptibility is highly variable among the Av. para-gallinarum isolates compared to previous studies. Future studies are required to develop better immunogenic strategies and eventually novel vaccine candidates to control the disease and reduce the risk of infection with multi-drug resistant Av. paragallinarum isolates.

The present study had a twofold objective, including the reconceptualization of medical tourists’ perceived risk in the COVID-19 pandemic and developing strategies to reduce medical tourists’ perceived risk during the pandemic. These two steps were referred to as a strategic-based approach. The first step defines medical tourists’ perceived risk as the subjective/cognitive (mind-driven) expectations and objective/actual (real-image driven) evaluation of the negative consequences/losses before/after making travel decisions to an unsafe COVID-19 destination. Following that, the associated dimensions were identified, such as psychological, financial, health, legal, performance, facility, and time risks. Finally, two main strategies (country-based and hospital-/clinic-based) were developed to create a safe COVID-19 destination. This study could make significant theoretical and practical contributions to strategic medical tourism management.

One of the main problems and concerns of today's world is the termination of fossil fuel resources as the most important current energy source in the world; for this reason, renewable energy has been considered as an alternative to fossil fuels.

The aim of this study is to formulate scenarios for the development of renewable energy in Iran with future study approach.

Based on the purpose, this research is an application that has collected information using qualitative-exploratory methods. We used interviews and expert panels for data gathering. In this study, the statistical population of managers and experts are knowledgeable and specialized in the field of energy, especially renewable energy, which according to the type of information required to conduct research, non-probabilistic sampling has been used.

A panel of experts was formed and the driving forces were identified. In order to determine the main drivers, two indicators of importance and uncertainty were used. According to the indicators of importance and uncertainty, the two driving forces of "emerging technologies" and "green and sustainable economy" were selected. Four scenarios were developed: "Environmental sustainability with green gold", "Temporary and unsustainable rise towards sustainability", "Productivity with black gold" and "Continuation of the current trend and the sinister cycle of the black disaster".

At the end of the scenarios compiled with the background, it was compared and analyzed to what extent the proposed scenarios of the present research are in line with the findings of those researchers.

To examine the GFAP and S100B ability in prevention unnecessary brain CT scan in mTBI and compare them with the single extremity fracture in orthopedic patients.

In this prospective cohort study, two orthopedics patients’ groups and mTBI patients were studied to assess the biomarkers’ ability in prevention unnecessary brain CT scan at the emergency setting. There were 40 orthopedics’ patients with single extremity fracture and 41 mTBI patients. Brain CT scans were done for all mTBI patients.

Brain CT scans showed no intracranial traumatic lesions. The median levels for S100B in the mTBI group was 14.8 (4.4-335.9) ng/L, and in orthopedic patients’ group was 13.3 (5-353.10) ng/L. Statistically significant differences were observed between both groups in S100B levels (p=0.006). The median Glial Fibrillary Acidic Protein (GFAP) levels in the mTBI patients’ group were 600 (400-16300) and in the orthopedic patients’ groups was 60 ng/L (300-14900). Statistically significant differences were observed between groups in GFAP (p=0.041).

Our results showed that S100B and GFAP serum levels were significantly higher in patients with mTBI than in patients with a single limb fracture.

The purpose of this study was eavaluation of morphological and biochemical haracteristics of rice seedlings–Domsia cultivar to various concentrations (0, 0.024, 0.048, 0.076 and 0.1 mM) of extracted phenolic compounds of barnyard grass (Echino crus-galli (L.) Beauv). The experiment was performed based on a completely randomized design in three replications in hydroponic culture. Methanol was used to extraction of the phenolic compounds. In other experiment, different concentrations of hydroxyl benzene synthesis (0, 1.514, 3.054, 4.569 and 6.136 mM) also was applied on this cultivar. According to the results, effects of different concentrations of phenolic compounds of barnyard grass on charactristics of root length, width of largest leaf, relative water content of leaf, protein and total phenols of rice seedlings were significant at 5% probability level. So that, the extent of negative impact on these traits were increased with increasing concentrations of phenolic compouds of barntyard grass in comparison with control. The greatest reduction of these traits was related to 0.1 Mm of phenolic compounds concentration, although there was no significant difference between this treatment and some treatments. According to the results, significant reduction effect of synthetic phenolic compounds concentrations on studied traits in addition to leaf area in plant and content of chlorophyll a, b and total especially at higher concentrations was more than treatments of its natral concentrations in barnyard grass. Due to the observed negative impact of phenolic compounds of barntyardgrass on rice seedlings–Domsia cultivar and also exstance of considerable amount of aromatic groups of benzene derivatives such

Infectious bursal disease (IBD) is a highly contagious immunosuppressive disease of young chickens caused by infectious bursal disease virus (IBDV). IBDV consists of a two-segmented double-stranded RNA genome which can easily undergo genomic recombination or reassortment during mixed infections.

The objectives of this study were aimed to characterize a previously identified Iranian IBDV strain (JRMP29IR) in specific-pathogen-free (SPF) chickens, evaluate the presence of a mixed and/or reassortant virus popula-tion in this strain, and examine the frequency of genomic recombination and reassortment in publicly available IBDV genomes through bioinformatics study.

The SPF chickens were challenged with the JRMP29IR strain via oral and intraocular routes. Bursal tissues were extracted for histopathological evaluation and reverse transcription-polymerase chain reaction (RT-PCR) followed by Sanger sequencing. Putative recombinations and reassortments were evaluated using the Recombination Detection Program 5.

Through genomic sequencing of the viruses from the bursas of infected chickens, the JRMP29IR strain was found which contained viruses from the classic, variant and very virulent IBDV genotypes. Through bioinformatics, nu-merous putative recombination and reassortment events were identified that naturally occur throughout the IBDV genome.

Parental JRMP29IR appears to be derived from a flock undergoing a mixed IBDV infection. High frequency of recombination and reassortment among IBDVs suggests that these events are evolutionarily beneficial for the virus

Without a doubt, plant hetrotoxicity is one of the important factors in determining the distribution and abundance of some species in plant communities. Thus, the purpose of this experiment was to evaluate the effect of phenolic composition obtained from the methanol extract of Echinochola crus-galli on germination traits and cytogenetic behavior of rice.

This experiment was done to assess hetrotoxic potential of various concentrations (0, 0.024, 0.048, 0.076 and 0.1 mM) of the phenolic composition obtained from the methanol extract of whole-organ of E. crus-galli on germination traits of rice as well as mitosis division of meristematic cells of radicle in a completely randomized design. To extract thephenolic composition, warm extraction method using a methanol solvent was used. For studying mitosis division, first rice seeds were germinated. Then, each of the steps such as fixation, hydrolysis, staining, squashing and microscopic studies were done on the end of the radicle. Mitosis indices and percentage of mitosis inhibition were calculated and also percentage of each of chromosomal abnormalities at four stages of prophase, metaphase, anaphase and telophase as compared to total cells was calculated.

The lowest percentage and rate of germination and relative germination were found in two concentrations of the 0.076 and 0.1 mM of phenolic composition of E. crus-galli, so that no germination was observed in these treatments. In this study, mitosis division was normal in control samples, so that the rice plant included 12 chromosomes in the metaphase stage. Also the chromosomes were normal in the telophase stage and chromosomal abnormalities were not observed in meristem cells of radicle tip of the control. The lowest value of mitosis indices and the number of dividing cells were related to the concentration of 0.048 mM wuth 30.19 and 385 cells, respectively. In the present study, chromosomal abnormalities in the stages of metaphase, anaphase and telophase were increased with increasing concentration of phenolic composition, and were 28.85 and 16.95% in 0.048 mM concentration of phenolic composition, respectively. The most chromosomal abnormalities were of sticky and laggard type, which were related to the concentration of 0.048 mM of phenolic composition with 39.83 and 32.25%, respectively. The highest number of chromosomal bridges and clumping were obtained in 0.024 mM of phenolic composition with about 19.27 and 29.83%, respectively.

In this study, phenolic composition obtained from the methanol extract of E. crus-galli had asignificant inhibitory effect on germination traits and mitosis division in root tip cells of rice. Thus, the amount of E. crus-galli residues in the field should be considered in direct and indirect cultivation of rice. Highlights: 1-Difference in impact of the phenolic composition obtained from the methanol extract of Echinochola crus-galli on germination and reduced cytogenetic behavior of rice is related to their threshold concentration. 2- It is advised to cultivate varieties of rice resistant to the remnants of harmful compounds of E. crus-galli as direct cultivation or under nursery condition.

Policy-making with the aim of technology development is the basic function of governments and their intervention process in order to achieve results and realize economic and social prospects. Policy studies seek to describe and explain the policy of governments and how to influence and change it. The field of energy, including renewable energy, as well as the development of renewable technologies, as one of the most important areas of public issues, is always affected by direct and indirect government interventions. In this regard, the purpose of this article is to investigate the challenges affecting the policy-making process of renewable technology development in Iran. For this purpose, the method of structural-interpretive modeling has been used to express the interrelationships between these challenges. In addition, MICMAC analysis has been used to identify the influence and dependence of each of the challenges. After analyzing the data, the challenges affecting the policy-making process of renewable technology development were classified into five different levels and according to the interrelationships between them, it was presented as a structural-interpretive model. Also, after MICMAC analysis, the variables were divided into three groups of dependent, independent, and autonomous variables, and no variables were included in the group of linked variables. The findings show that "supporting successful innovators", "capital raising capacity", "uncertain start-up costs" and "proving the effectiveness of policies" are among the main challenges affecting the policy-making process of renewable technology development in Iran.

Today, organizational knowledge is recognized as a very valuable intangible resource for gaining a competitive advantage. Managing such intangible assets is essential for maintaining and gaining a competitive advantage for organizations, especially knowledge-based companies whose survival and success are tied to knowledge. Knowledge can improve and enhance the performance of organizations when shared across the organization. Despite the vital role of internal knowledge sharing, little research has been done on the factors affecting knowledge internal knowledge sharing in knowledge-based companies. For this purpose, in the present article, first, by reviewing the background, the factors affecting the internal organizational knowledge sharing in organizations were extracted, and then, using the DEMATEL method, the relationships of these factors and their prioritization have been studied. The present study is a descriptive and survey research and is a tool for collecting secondary data (library studies) and primary data (questionnaire). After designing the questionnaire and confirming its validity by experts, the questionnaire was distributed and filled by 30 experts and managers of knowledge-based companies located in S&T Parks of Shahid Beheshti University, University of Tehran, and Tarbiat Modares University. The research results show that formal and informal procedures, open-door policy, and knowledge sharing strategy are the most influential factors and in contrast to communication and network, people's knowledge and interactive memory system are the most influential factors.

Due to its geographical conditions, Iran is one of the countries with high potential in the field of solar energy production, which has not been exploited properly. The present study investigates the critical study of solar energy governance in Iran. The present study in terms of applied purpose, in terms of qualitative method, and its research community are experts with experience and expertise in the field of solar energy governance in Iran. The sample size includes 27 people who have been selected by the snowball technique. Data collection tools are semi-structured interviews and secondary data and the methods of data analysis are content analysis and coding. The temporal territory is from 2001 to 2019. Based on the findings, the research obtained from the analysis of governance requirements with a comprehensive approach, policy incoherence in policy documents, lack of horizontal coordination between policymakers and regulators, vertical lack of coordination between policymakers and executive bodies and the inability of Supreme Councils including the Supreme Energy Council to coordinate. Eventually, it's have led to loss incoherence and integration among actors that solar energy and its lack of proper use in Iran.

This paper aims to analyze the historical evolution of solar photovoltaic technology development in Iran with an emphasis on the role of physical and hard Institutions in the period from 1991 to 2020. To this end, while examining the concept of Institution and its implications in the backgrounds and experiences of other countries. We have analyzed the role of physical (organizations) and hard Institutions (laws, policies, and regulations) and their effectiveness in the development of solar photovoltaic technology in Iran during the three main periods of development of this technology. The present study is of applied purpose and qualitative research method. Data gathering tools are semi-structured interviews and secondary data and the method of data analysis is through content analysis and axial coding. The statistical population for the expert interview is experienced in solar energy in Iran and 18 experts have been selected and interviewed by the snowball technique. Its temporal territory is between 1991 and 2020, and its spatial territory is Iran. According to the findings of this study, in the first period (1991 to 2006) the institutional focus was on familiarizing authorities with renewable energies and promoting this energy. While in the second period (2006 to 2015) the institutional focus has been shifted towards supporting the development of solar photovoltaic technology and in the third period (2015 to 2020) the institutional orientation has been directed towards creating a renewable and solar energy market in Iran.

identification and explanation of the technological change. On the other hand, the development of renewable energy technologies in each country according to its native conditions has different requirements and depends on a range of social and technical factors. The present study analyzes the development of photovoltaic technology from the perspective of expectations, networks, and learning, with the approach of strategic niche management and in the form of historical case studies and qualitative research methods. Data gathering tools are semi-structured interviews and secondary data and the method of data analysis is through content analysis and axial coding. The statistical population for the expert interview is experienced in solar energy in Iran and 20 experts have been selected and interviewed by the snowball technique. Its temporal territory is between 1991 and 2019, and its spatial territory is Iran. Examining the Interaction between niche processes, it was shown that although the network of actors was weaknesses in the early 1991s, with over time and the Enforcement of supportive laws and policies such as feed-in tariff and support for the development of renewable energy technologies, it has finally led to the growth of the network of educational and knowledgeable actors in the mid-2000s and the growth of the network of production and service actors in the 2010s. The impact of important events such as JCPOA and foreign investment on the development of expectations and the network of photovoltaic actors has also been described.

This study was aimed to evaluate the site-specific drug delivery of 5-FU with chitosan(CS) as a carrier and quercetin (Qu) against induced colon cancer in Wistar rats. Cross-linked CS-Qu nanoparticles (NPs) were prepared by ionotropic gelation method.Physicochemical characterization of NPs was performed by Fourier-transform infrared (FTIR)spectroscopy, dynamic light scattering (DLS), in vitro drug release, and drug loading efficiency(LE). 1, 2-Dimethylhydrazine (DMH) and dextran sulfate sodium (DSS) were applied to induceadenocarcinoma tumors on inbred male Wistar rats’ colon. The treatment group of rats wasadministered through enema with NPs dispersion. Hematoxylin and eosin staining were performedto the histopathological examination of tumors. Zeta potential and particle size for NPs were +53.5 ± 5 mV and 179 ± 28 nm, respectively.About 96% Qu LE was obtained with a maximum release of 5.63 ±1.59% and 4.62 ± 1.33%after 24 hours in PB solution with pH values of 6 and 7.4, respectively. The numbers of 8 to 21tumors were observed in all rats administered with DMH and DSS. Significantly decreasing ofmicrovascular density and mitosis count was detected in the treatment group in comparison withcancerous group (P = 0.032 for the former compared to P = 0.016 for the later), respectively.Furthermore, the treatment group showed a high apoptosis rate (P = 0.038). The developed Qu-loaded CS NPs were good candidates for site-specific andsustained drug release in enema treatment. Decreasing of microvascular density and mitosiscount, along with increasing the apoptosis percent in the treatment group proved that the NPscould have promising results in site-specific and sustained drug delivery against colorectal cancer.

Tourism literature is devoid of a concept by the name of the Smart Tourism Organization (STO). Given the lack of research into this concept, some questions arise around it. For instance, given the advances in tourism in the new millennium, what has changed in the structure of tourism service organizations? Considering the competitive nature of the tourism industry and the technologies advancement, can the traditional structure of tourism organizations satisfy tourists, managers, stakeholders, and employees? The present study was conducted with a comprehensive approach to organizations in the postmodern era (Hatch, 2018) and seeks a new type of organization for the subject of STO. This new type of organization recognizes the different dimensions of intelligence in the external environment of organizations and seeks to train them. The primary purpose of this study is to select the dimensions of intelligence in tourism organizations and the effect of these dimensions on the development of a smart tourism organization according to the situation of this industry. The Delphi method of the panel of experts was used to reach a consensus about the dimensions of smart tourism organization and to design the questionnaire. Fist, the literature on the subject was fully reviewed. The variables related to the topic were then extracted, and the Delphi method was used to confirm these variables and their relevant questions. A total of 24 management faculty members (Ph.D.) and senior tourism officers were selected as members of the Delphi panel. Twelve people with specialist organizations and 12 people with tourism expertise were also selected for the panel. After four Delphi rounds, the consensus was reached on the questionnaire and its variables. In the next stage, the questionnaire validity and reliability were measured, and their data are presented in the quantitative analysis section. The research population consisted of all the experts working at tourism organizations in South Khorasan Province, including Iran, tourism agencies, hotels, and experts of cultural heritage, handicrafts and tourism in this province. The census method was used to determine the statistical sample of the research. The questionnaires were distributed among 37 tourism organizations and 356 experts (See Table 1). In the last step, for the quantitative analysis of the data, Smart PLS and SPSS software were used.
  According to tables R2 values of 0.536 are substantial for the proposed model. Tanenhaus et al. (2004) suggest the Goodness of Fit (GoF) test for a PLS path model validation globally and specifically (Henseler and Sarstedt, 2013:569). The GoF is defined as follows:R2: 0.536 To determine the quality of the GoF of the overall PLS-SEM model, Witzels et al. (2009) suggest the following criteria: GoF small (0.10), GoF medium (0.25), and GoF large (0.36). Accordingly, the GoF of the model is confirmed with a value of 0.616. The model is confirmed and the hypotheses are tested in Table 6. The present study is thus the first step in expanding the field of smart tourism organization in tourism literature that has contributed to the design of a model and presented dimensions that can be further developed and transformed in the future by other researchers. STO can be considered an introduction to a new form of tourism business. This study is the first attempt at developing STO and identifying the diverse dimensions of this concept. The findings may help tourism organization managers and other researchers better identify and develop intelligence in tourism organizations and research, especially given the limited works of research dedicated to tourism organization and management.

Modern technologies used for the tourism organization have eliminated a number of occupations and specializations and have instead created some new occupations and specializations. While the structure of tourism service provider organizations in the southern Khorasan province has retained its traditional form and the need to identify smart performance factors in tourism and change the structure of organizations providing these services is felt. The present study aims to identify the intelligent factors in the tourism industry of South Khorasan. The research society includes all official experts of tourism organization of South Khorasan Province. To determine the statistical sample of the research, the census method was used. Out of 356 distributed questionnaires 350 number of them that were completed correctly, collected and analysed. The questionnaire is the researcher made that to the design of it the Delphi technique is used. Then reliability and validity of it were investigated by the Structural-divergent method. The final results indicate that providing electronic services for tourists, Trained and fluent foreign language staff, providing services and complementary products, provide smart travel experience, the open mind, and tourism innovation and finally use of modern tourism marketing methods has the greatest impact on the intelligent performance in tourism.

Despite significant changes and developments in the tourism industry in South Khorasan Province, there is almost no systematic and scientific investigation in this area. Given the region’s population, the number of tourism agencies and related activities has increased. However, these businesses are not stable, and managers of such agencies leave their businesses after a period. Employees, too, dislike their working conditions. This study followed an applied and descriptive approach. The study included all tourism agencies in South Khorasan and considered all their employees. The statistical population comprised 105 employees of tourism agencies. Data were gathered based on a standard questionnaire where scores above 4 showed problems with the functionality of organizations; scores closer to 7 illustrated essential problems; and the scores below 4 showed negligible problems. Weisbord Six-Box Model was used to analyze the data. The results showed that the tourism industry in South Khorasan was not in proper condition and that people working in this area were looking for some improvements in their conditions.

Extrahepatic biliary atresia (EHBA) is one of the main causes for neonatal cholestasis. It’s early diagnosis could help infants with early surgery and increase the survival. In this study we evaluated the diagnostic accuracy of procalcitonin and apolipoprotein E (Apo-E) levels in infants with and without EHBA. In this prospective study, 18 infants with EHBA and 15 infants with other causes of cholestasis were included. Blood samples were taken from each patient and different markers including procalcitonin and Apo-E levels were measured. ROC analysis was used to define sensitivity, specificity, positive and negative predictive value (PPV and NPV) for procalcitonin and Apo-E. Gamma-glutamyl transpeptidase (GGT) and alkaline phosphatase were significantly higher in EHBA than other causes of neonatal cholestasis. There was significantly positive correlation between Apo-E and SGOT (r=0.37, p=0.03), SGPT (r=0.38, p=0.02) and GGT (r=0.38, p=0.02), and inverse correlation between procalcitonin and GGT (r=-0.45, p=0.01). Area under curve (AUC) for procalcitonin was 0.69 (p=0.053) with cut-point of 0.735 ng/ml. The sensitivity, specificity, PPV and NPV was 67%, 61%, 69% and 59%, respectively. AUC for Apo-E was 0.68 (p=0.06) for cut-point of 61.25 ng/ml with sensitivity, specificity, PPV and NPV of 67%, 67%, 71% and 67%, respectively. Both PCT and Apo-E have relatively good accuracy in diagnosing EHBA cases; we could not rely on these markers for diagnosis of EHBA, however, combinations of these biomarkers with other markers and imaging tests could improve their accuracy and may help for rapid and accurate diagnosis of EHBA.

Popularization domain has also covered the scientific theories and among them, theories of popularized ethics have emerged. Focusing on human mind and its independence, popularized ethics simply takes human mind, rather than religion, as the ultimate reference of ethical criteria as well as the norms governing the human characteristics and behavior. Rejecting the religious ethics, Adel Zaher, Arab-decent contemporary scholar, sees the epistemological foundation of ethics in human independent mind. For him, ethics is logically independent of religion and it is possible to achieve the epistemological foundation without religious knowledge. He attempts to deny the claim that religious epistemology is prior to ethical epistemology and dependency of the latter to the former. Enumerating the theories viewing religion to be dependent on ethics and, consequently, ethics popularized, this paper intends to analyze and criticize Adel Zaher’s viewpoint of popularized ethics.

Virtually all religions include a code of moral conduct. In fact, the only feature of religion that comes close to being universal is a practical one: to offer human beings a way to cope with the human condition, particularly suffering and death. Coping might be aided by the promise that suffering will eventually be overcome, or it might involve seeing suffering as a natural consequence of wrongdoing in a past life, or it might involve changing the way humans perceive suffering.
In any case, suffering has to be faced, and it cannot be faced without first understanding it. Most religions give a diagnosis of the human condition and an explanation for the existence of suffering and death, as well as a remedy for the problem. Moral behavior as defined by the particular religion is part of the remedy, but each religion teaches that the ultimate goal of moral living is unattainable without the practice of that religion. So not only is morality an intrinsic feature of almost all religions, but most also teach that morality is incapable of standing alone