فهرست مطالب m.r. jalali

Thyroid cancer is the most common endocrine malignancy. The most common well-differentiated form of thyroid cancer is papillary carcinoma (PTC). Few studies on determining the role of CD10 in PTC prognosis have been performed, furthermore they have been controversial. This study was designed to determine the correlation of CD10 expression with age, gender, tumor size, lymph node involvement and capsular invasion as prognostic factors of PTC.
This study was a cross-sectional descriptive-analytic study. Data concerning age, gender, tumor size and lymph node involvement were derived from the medical records of 85 patients diagnosed with PTC that underwent thyroidectomy in Mostafa Khomeini Hospital between 2011 and 2014. With the help of four micrometer sections made from paraffin embedded blocks, CD10 expression was assessed by immunohistochemistry. Another section was stained with Hematoxylin & Eosin and capsular invasion was evaluated by light microscope.
In this study 88.24% of patients were female and 11.76% were male. 41.2% of samples were CD10 positive. A significant correlation between CD10 and tumor size, lymph node involvement and capsular invasion was found. There was no significant correlation between CD10 expression and the age or gender of patients.
CD10 oncoprotein expression is correlated with increased tumor size, lymph node involvement and capsular invasion. Therefore CD10 can be used to assess PTC prognosis.

Psychological and behavioral domains involve important issues in coping with diabetes. Therefore, this study was conducted in order to investigate the relationship between resilience and hardiness in patients with diabetes 2 in Yazd. This study is a descriptive-correlation study which the sample consisted of 310 diabetic patients (160 women and 150 men). In order to glean the study data, Caner and Diveson psychological resilience and Ahvaz psychological hardiness questionnaires were applied. Data analysis was performed via SPSS18 software utilizing Pearson correlation and independent T-test. The study results indicated that a significant correlation was observed between resilience and hardiness in each group as well as within all patients with diabetes. Comparing the means of the two groups in regard with resilience and hardiness, it was demonstrated that the differences between men and women with respect to hardiness was significant (t=3/19, p=0/04), though the means of the two groups for resilience was not significant. Regarding the positive relationship between hardiness and resilience, it could be expected that employing proper treatment in order to increase resilience and hardiness in diabetes, will lead to a decrease in perception of psychological problems, as well as an increase in quality of life.