maryam razavi

In December 2019, the COVID-19 pandemic began in Wuhan, China with the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Based on evidence, pregnant women are more vulnerable to respiratory infections due to physiological changes in their bodies.

The purpose of this study was to investigate the outcomes for mothers and newborns in the Sistan and Baluchestan province who tested positive for SARS-CoV-2 during pregnancy.

The current retrospective study assessed 100 SARS-CoV-2-positive pregnant women and 50 healthy controls from hospitals affiliated with Zahedan University of Medical Sciences during 2019 - 2020. The data included demographic, clinical, and neonatal details, which were analyzed using both descriptive and inferential statistics with SPSS software version 25.

Our findings revealed that preterm birth occurred in 37% of pregnancies with COVID-19, and other complications such as acute respiratory distress syndrome (21%) and stillbirth (10%) were also prevalent. The majority of mothers (24%) were asymptomatic, with shortness of breath identified as the primary symptom (17%). Cesarean section rates were 30%, and miscarriage occurred in 2% of cases. Notably, complications such as placental abruption, meconium aspiration, and cardiorespiratory arrest were infrequent. Compared to mothers in good health, the outcomes for the newborns showed a significant difference in preterm birth (37% vs. 14%, P = 0.004) and premature rupture of the membranes (13% vs. 2%, P = 0.035).

This study emphasizes the increased risk of preterm birth and associated complications, along with varied maternal and neonatal outcomes in pregnancies positive for SARS-CoV-2. The findings contribute to the understanding of COVID-19's impact on pregnancy outcomes, urging further comprehensive investigations for enhanced insights and the development of improved maternal-fetal care strategies.

Increased body temperature (fever) is a common clinical indicator of disease and can lead to altered metabolism and subsequently threaten life. studies have shown antimicrobial, analgesic/antipyretic effect for some Eucalyptus and Mentha species. Therefore, in the present study we assessed the effect of the combination of mint (Mentha), eucalyptus, evening primrose, and basil on lowering body temperature.

This experimental study was performed on 30 rats in five groups. A hydroalcoholic extract was prepared from each plants using ethanol as solvent and concentrated with a rotary apparatus. Then the extracts were combined in equal proportions. To induce fever, the brewer's yeast fever induction method was used by intraperitoneal injection of a 20% aqueous suspension. The febrile rats were then divided into groups receiving different doses of the mixed extract (200, 500, 750 mg/kg); normal saline and paracetamol were used in control groups. Rectal temperature was measured with a digital thermometer before injection and 6, 8, 12, and 16 hours after extract injection. The analysis of variance with repeated measurements was used to evaluate the effect of hydroalcoholic plant extracts on fever changes.

The mean fever in the intervention groups with all effective doses decreased over the hours, and the mean fever with a dose of 750 mg decreased more than in the other groups (P-value < 0.05). We had the lowest fever at a dose of 750 mg and a time of 16 hours (P-value < 0.05).

The results show that the combined extract can reduce body temperature in rats, and by increasing the effective dose, the recovery rate and temperature reduction are faster and more effective.

For many years, hysterosalpingography was considered as the gold standard for the diagnosis of uterine cavity abnormalities, and today, hysteroscopy has been proposed as a complementary method. The present study was conducted with aim to investigate the accuracy of findings of undiagnosed filling defects in hysterosalpingography by hysteroscopy in infertile women.

This cross-sectional (descriptive-analytical) study was conducted in 2020-2021 on 107 infertile women referred to Ali Ibn Abi Talib (AS) Hospital of Zahedan. Hysterosalpingography was performed for women and they had undiagnosed filling defects. After performing hysteroscopy, a questionnaire was recorded for each patient including: patient's age, age of infertility, type of infertility and hysteroscopy findings. Data were analyzed by SPSS software (version 24) and chi-square, Fisher, and Binomial tests. P<0.05 was considered statistically significant.

64 patients (59.81%) had primary infertility and 43 (40.18%) had secondary infertility. The most pathological finding in hysteroscopy was polyp that was observed in 34 patients (31.77%) which were most frequent in the age range of 35-40 years. Also, 80 patients (74.76%) had abnormal hysteroscopy findings and 27 (23.25%) had normal findings. According to the Binomial test, there was a statistically significant difference between the percentage of normal findings between hysteroscopy results and filling defects without hysterosalpingography (P<0.001).

Hysterosalpingography is a simple method for diagnosing abnormalities of the female reproductive system, but it is less sensitive than hysteroscopy. Therefore, hysteroscopy can help for more accurate and better diagnosis in examining the condition of patients with infertility.

The importance of dietary pattern and vitamins in the incidence of cancers has been demonstrated in many studies. As there are cultural differences and various dietary patterns in different countries, the results of other studies are not necessarily applicable to our society. This study aimed to evaluate the role of some vitamins and dietary patterns in developing head and neck cancer. Dietary pattern and serum levels of vitamins in 39 patients with head and neck squamous cell carcinoma (HNSCC) were compared to 37 healthy individuals. A native questionnaire was used to obtain the dietary pattern. The existence of a significant relationship between serum levels of vitamins and dietary pattern with the risk of HNSCC was assessed. The independent t test, chi-square and exact Fisher’s test were employed for statistical analysis. The mean serum levels of these vitamins in the case group were significantly lower as compared to the control subjects (P < 0.005). Two dominant eating patterns were identified, and after adjusting for confounding factors such as age, education, physical activity, body mass index (BMI), and place of residence, it was found that people with unhealthy dietary patterns were 6.55 times more likely to develop cancer than people with a healthy diet. Lower serum levels of vitamins C and E are associated with an increased risk of HNSCC. Unhealthy dietary patterns also increase the risk of developing this cancer.

Most clinicians prefer to apply more readily accessible clinical techniques for the diagnosis of bacterial vaginosis, which at the same time are time-conserving and highly accurate. The current cross-sectional study sought to evaluate the bacterial vaginosis diagnostic tests on 87 pregnant women referred to our center due to vaginal discharge using Amsel criteria and the Nugent scoring system. Our results showed that the Amsel criteria had a significantly higher sensitivity/specificity than the Nugent scoring system regarding the number of clue cells in the vaginal wet mount test. The specificity of a combination of the wet mount of clue cells in the vagina with other Amsel criteria along with the Nugent scoring system was much higher than both the Amsel criteria and Nugent scoring system. We observed that due to the high efficacy and the great time-conserving and economically-friendly nature of the Amsel criteria, the method is usually opted for by clinicians.

The world's population is growing exponentially, and people are facing significant problems such as hunger and extreme malnutrition. According to some people, the production of genetically modified foods can be a good solution to provide healthy and adequate food and thus solve global hunger. The production of genetically modified foods has also met with much opposition. A group of opponents, by presenting theological reasons, consider the production of genetically modified foods to be immoral and disgusting on their own, regardless of the consequences. This paper seeks to examine and critique the most important theological reasons for opposing the production of genetically modified foods, such as playing the role of God, crossing species boundaries, violating the intrinsic value of plants and animals, and changing creation. The results show that these reasons are not sufficiently convincing and cannot prove the immorality of the production of genetically modified foods, although this is not necessarily the case.

Proper reduction of labor pain has always been one of the most important goals of medicine and the patient's request for labor pain relief is a sufficient necessity for the use of pain relief methods. The aim of this study was to evaluate the maternal and fetal outcomes of mothers who underwent spinal analgesia in comparison with the control group in mothers who referred to the maternity ward of Ali Ibn Abitaleb Hospital in Zahedan in 2020.

The present study was a case-control study that was performed on 200 pregnant women in 1398. Pregnant women whose criteria for admission and selection of ananesthesiologist were divided into painless (spinal) delivery groups. The control group was selected by simple random sampling from among those who met the inclusion criteria but did not want to have a painless delivery. The two groups were compared usingANOVA, Kruskal-Wallis, Linear regression, Chi-Square and Fisher's exact tests. A significance level of 0.05 was considered.

The length of the first and second stages of labor in the non-intervention group was significantly shorter than the painless groups. In the analgesic method used, the Apgar score of the infant had no negative effects on the type of delivery and did not lead to complications in the mother in the postpartum stage.

Findings from this study showed that spinal analgesia had no negative effects on maternal and neonatal outcomes.

One of the latest advances in biotechnology is genetically modified (GM) foods. The production of GM foods is a controversial issue worldwide. The most important and controversial issue in the production of GM foods is ethics. Some people believe that their production is morally right, while others consider the production of these foods to be unjustified and immoral. According to the principle of beneficence, proving the ethics of producing GM foods is only possible by carefully evaluating its advantages and disadvantages and the superiority of the benefits. Opponents believe that the production of this type of food has irreparable disadvantages, some of which are known and some are still unknown. Damage to human health and the environment and the creation of economic, social and political problems are among the most important reasons for opposition. On the other hand, proponents of the production of GM foods enumerate significant advantages. Solving the problem of global hunger, improving the quality of food, and improving the economic situation of farmers are among the most important reasons for the proponents of the morality of the production of GM foods. In the present study, the reasons of the proponents of GM food production are examined and criticized through descriptive and analytical methods. Studies show that although the production of GM foods is associated with significant benefits, there are drawbacks to the opponents’ reasons, and the production of GM foods requires more research and experiments.

This study was designed to investigate the effect of tranexamic acid and its side effects in preventing postpartum hemorrhage in patients referred to Ali ibn Abitaleb Hospital in Zahedanduring 2020-2021.

Patients were divided into two groups of 85 patients. Vital signs as well as drug side effects related to tranexamicity are monitored and recorded every 15 minutes in the first hour and every 30 minutes in the second hour. Also, blood samples are taken from patients to measure hemoglobin and hematocrit within 6 hours after delivery. The number and weight difference of droschitis used during 2 hours after delivery are also measured. In addition, PPH (Postpartum hemorrhage) cases in both groups were checked by repeated examination of the uterine fundus during the first 2 hours and after 6 weeks.

There was no statistically significant difference between the two groups in terms of the number of deliveries and further decrease in hemoglobin levels in the control group compared to the intervention group. Nausea, vomiting, and dizziness were observed in the intervention group and thrombosis was not observed in any group. According to the independent samples t-test, there was a statistically significant difference between the mean blood volume lost between the two groups. The mean hematocrit drop was statistically significant between the two groups. No blood transfusion was observed in any of the patients.

Tranxamicacid injections can effectively reduce postpartum hemorrhage and reduce maternal hemoglobin and hematocrit following this complication.

 A high prevalence of vitamin D deficiency exists in Iranian people. Vitamin D plays a significant role in the pathogenesis of infertility.

 This study aimed to compare the serum levels of vitamin D in women with unexplained and male factor infertility admitted to the Infertility Center of the Ali ibn-e Abitaleb Hospital, Zahedan, Iran, in 2018.

 This case-control study was performed on 155 women in two groups: a case group consisting of 105 women with unexplained infertility and a control group consisting of 50 women with male factor infertility admitted to the Ali ibn-e Abitaleb Hospital. Blood samples were taken from all the subjects and sent to the laboratory to determine the vitamin D level. Descriptive statistics, including frequency, percentage, mean, and standard deviation were used to describe the data. Also, the mean serum vitamin D level was determined using an independent t-test and the Mann-Whitney U test, and the rate of P < 0.05 was considered significant.

 The results showed that vitamin D levels were significantly lower in the case group than in the control group (P < 0.001). The mean vitamin D level was 23.68 ± 6.88 in the case group and 10.90 ± 11.11 in the control group.

 The vitamin D level was lower in women with unexplained infertility than in women with male factor infertility. Therefore, measures need to be taken to prescribe vitamin D supplementation to infertile women.
 

In this interventional study, 120 primigravid women with low bishop scores who visited the maternity room of Ali ibn Abitaleb Hospital in Zahedan (2014) were selected. Patients were randomly assigned to receive syntocinon, misoprostol, or transcervical catheter plus syntocinon. Variables including success rate and side effects were compared among the groups. The success rates in the syntocinon, syntocinon Group plus the trans-cervical catheter, and misoprostol groups were 72.5%, 77.5%, and 65%, respectively, showing no significant difference between the three groups (P = 0.711). The rates of drug adverse effects in the syncinosin, syncinosin plus trans-cervical catheter, and misoprostol groups were 7.5%,7.5%, and 2.5%, respectively. According to the obtained results, the three methods of syntocinon, misoprostol and transcervical catheter with syntocinon, which are low-risk and effective methods for cervical ripening, could be used to terminate pregnancy in primigravida women with low Bishop score before the initiation of labor induction.

The risk of preterm labor is significantly higher in women with a history of preterm delivery. The current study aimed at investigating the effect of 17 -hydroxyprogesterone caproate (17-OHPC) on preterm labor prevention in pregnant women with a history of preterm labor. In the current randomized control trial, 100 pregnantwomenwith a history of preterm labor were divided in two groups. The 17-OHPC 250 mg was prescribed to the case group from the week 20 of gestation weekly. Sampling was done randomly. The gestational age at birth was measured up and compared with that of previous labor. Data were analyzed using t-test. In the current study, the mean gestational age of previous and present labor were respectively 28.5  5.9 and 33.6  5.2 weeks in the case group (P = 0.001). In the control group, the mean gestational age of previous and present labor were 33.32.7 and 35.3  2.3 weeks, respectively (P = 0.001). The difference between the previous and present gestational age in the case and control groups were 5.14.0 and 3.31.4 weeks, respectively (P = 0.228). The birth weight in the case and control groups were 2.40.1 and 2.70.7 kg, respectively (P = 0.256). The 1-minute Apgar score in the case and control groups were 7.32.3 and 7.81.7, respectively (P = 0.494). Also, the 5-minute Apgar score in the case and control groups were 8.62.2 and 9.11.4, respectively (P = 0.393). In the current study, the number of infants requiring admission to the neonatal intensive care unit in the case and control groups were 16 (32%) and 14 (28%) respectively, although the difference was not statistically significant (P = 0.711). The results of the study indicated that although gestational age at birth was higher in the case group than in the control group, the difference was not statistically significant.

Uterine leiomyoma is the most prevalent benign uterine tumor in women which develop in nearly 20-40% of women of reproductive age. Pregnancy in women with uterine leiomyoma is considered as a high-risk pregnancy that lead to many complications. This study was performed with aim to investigate the relationship of uterine leiomyoma with premature rupture of membranes in pregnant women. This descriptive-analytical study was conducted on 500 pregnant women referred to Ali-ibn Abi Talib Hospital in Zahedan from April 2015 to March2017. The qualified pregnant women were divided into two groups of leiomyoma and non-leiomyoma, based on the presence of uterine lymphoma diagnosed in early pregnancy ultrasound. Two groups were examined for number, size and location of leiomyoma. Data were analyzed using SPSS software (version 21), descriptive and Chi-square tests. P<0.05 was considered statistically significant. Among 500 pregnant women who were included in the study, 18.6% (N=93) had uterine lymphoma and 81.4% (N=407) were without uterine leiomyoma. The prevalence of premature rupture of the membrane in the uterine leiomyoma group was 25.85% (N=24) and 9.33% (N=38) in without uterine leiomyoma group. There was significant relationship between premature rupture of membranes with the number and location of uterine lymphoma in pregnant women (p <0.001). There was significant relationship between premature rupture of membranes with uterine leiomyoma (number, size and location). Premature rupture of membranes was more prevalent in intramural mayoma and in mayoma with diameter more than 5 cm.

Enterobacteriacea are able to cause urinary tract infections, and Escherichia coli (E. coli) and Klebsiella pneumonia are the most frequently isolated pathogens from urinary samples. Untreated urinary tract infections can cause upper and lower urinary tract infections. These are among the most common infectious diseases in children. Septicemia and antibiotic resistance of urinary bacteria are the most important concerns in the developed and developing countries. One of the solutions for antibiotic resistance is herbal therapy, which as a branch of traditional medicine, has served an important role in disease treatment during the past century. The advantages of herbal therapy include minimum complications, cost-effectiveness, and high popularity. Herbalism has had a significant role in disease treatment. In this study, the antimicrobial effect of Pistacia atlantica was investigated in 2014. This cross-sectional study was performed on 150 patients with positive urinary cultures in Imam Ali Hospital of Zahedan, Iran. All the cases of positive culture during three months were investigated. Extraction of ethanolic extract of Pistacia atlantica was performed by a rotary device. Firstly, the antibacterial effect of Pistacia atlantica was assessed with the disk diffusion method at four concentrations, and then for bacteria that were sensitive to this extract, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. Antibacterial effect of Pistacia atlantica ethanolic extract on urinary tract infection was compared with some conventional antibiotics, and the data were analyzed using Chi-square test in SPSS. E. coli, Klebsiella pneumonia, and Staphylococcus aureus were isolated from urinary samples. Ethanolic extract of Pistacia atlantica created maximum non-growth halo at the concentration of 100 mg/mL, but at the 12.5 and 25 mg/mL concentrations the extract created minimum non-growth halo, indicating the bacteria were resistant in these concentrations. Overall, 27 of 150 bacteria showed sensitivity to Pistacia atlantica at the 50 and 100 mg/mL concentrations. The most sensitive bacteria to this extract were E. coli and Staphylococcus aureus, respectively. The results presented the antibacterial effect of ethanolic extract of Pistacia atlantica is higher at higher concentrations.

Matthiola incana is one of the most important cut flowers in Iran. This study was conducted to evaluate the effects of light intensities on the morphological and physiological characteristics of Matthiola incana, cv. Miracle White. The experiment was conducted based on completely randomized design with 5 treatments, 5 replications and 2 observations. The light intensities of this study were 150 (as control), 225, 300, 375 and 450 μmolm-2s-1. Parameters measured were included plant height, area and number of leaves, fresh and dry weight of leaves and stems, total chlorophyll, chlorophyll a and b, carotenoids, anthocyanins and total soluble sugars. The results showed that the area and number of leaves were increased significantly with increasing light intensity to 300 μmolm-2s-1 (30 and 19% respectively) and then were reduced with increasing more light intensity. Also fresh and dry weight of leaves and stems were increased significantly (up to 25%) by increasing the intensity of light to 300 μmolm-2s-1. In this research, the plant height was decreased with increasing light intensity and this reduction was significant in 450μmolm-2s-1. The amount of anthocyanin was significantly increased by addition of light intensity. The study also showed that the increasing of light intensity to plant tolerance level caused to increase photosynthetic pigments and total soluble sugars more than control. In general, the results of this research showed that light intensity can induce positive and favorable effects on growth and flowering of Matthiola.

Hyoscine-N-butylbromide is a potent anticholinergic agent with its prominent spasmolytic action on uterus and cervix smooth-muscle in the first stage of labor. This study aimed to evaluate the effect of Hyoscine-N-butylbromide on the acceleration of labor and rupture of the cervix in primigravida women.
This double-blind randomized clinical trial was conducted at Ali Ibn-e- Abi Talib hospital of Zahedan on primigravida women (n=105). With the initiation of active phase of labor either Hyoscine-N-butylbromide (40 mg, i.v.) or Saline (2 ml) was administered. Duration of the first, second and third stages of labor and the rate of cervix rupture were compared in two groups.
A significant difference was seen for the duration of the first stage of labor (181±59.1 versus 208.2±48.5 min) in two groups (P=0.012).There was no significant difference for the duration of the second and third stages of labor. Although rate of cervix rupture was lower in the Hyoscine group, no significant difference was observed between the two groups.
Hyoscine-N-butylbromide is effective in accelerating the first stage of labor and has no effect on the rate of cervix rupture and postpartum hemorrhage.

Electrospray is an atomization method which produces monodisperse and fine droplets by applying a high potential difference between a nozzle and a counter electrode. Therefore liquid meniscus shows different behaviors when flow rate or applied voltage varies in the electrospray method. Here we report experimental study of these modes based on observation of the liquid meniscus shape emitted from the nozzle. The formation of different modes is reported and forces acting on the meniscus in each mode is discussed. In this work classification of electrospray modes is reviewed for wide range of flow rates, between 0-80 ml⁄h, and voltage, between 0-8.5 kV. Electrospraying of ethanol is studied as a promising clean fuel for wide range of voltages and flow rates. Formation of dripping, sibling, spindle, micro spindle, intermittent cone jet, oscillating Jet, precession, cone-jet, multi jet, simple jet and ramified jet modes is observed. It should be noted that all of this study such as identification of mode shapes have been done according to taking photo from electrospray phenomenon by method of shadowgraphy, and this method has been done by using a high speed camera and a high resolution camera. In present configuration, for all of flow rates, there is the dripping and sibling mode for all of voltages which are lower than 3kV, for voltages between 3-4kV the spindle mode will be seen and for the voltages which are more than 5.5kV the multi jet mode will be observed. There are the other mode shapes for voltages between 4-5.5kV.

The queue is one of the most complex social systems in which human lives are inevitably ýassociated with the activities of organizations. Due to the characteristics of healthcare ýorganizations and the critical role that planning plays in such organizations, research in this regard ýcan be of great help. This paper was an attempt to demonstrate the role and use of the branches ýof the operations research discipline in healthcare centers.
The current research was a cross-sectional study conducted onþ þý2614ýþ þpatients referred to the ýparaclinic ward of Hafez Hospital, Shiraz, Iran. In order to collect data, the patient code, time of arrival, work start time, serving start and end time were recorded with the help of staff and two assistants at the time of arrival of the patients. Then, modeling and optimization of patient flow were conducted using queues and simulation techniques. The data was analyzed using SPSS software and Input Analyzer ýSoftware and the system was simulated using Arena software.
The results showed that 30% of the patients no longer wished to be referred back to the center. ýThe findings also revealed that there was a significant difference between the standard waiting ýtime and the time spent in the hospital to recive a service. Among the 6 different scenarios, the ýmixed scenario reduced waiting time of the first service forþ þsonography patients to 75.04 minutes ýand for radiology patients to 65.573 minutes.
The results showed that the suggested model, in comparison to the current model of health ýcenters, can improve theþ þquality of services and reduce the duration of time patients must wait ýuntil receiving the first serviceþ.

Any damages to the nerve fiber blocking connection with the neurons cell body (vital cell substances synthesis part), can lead to degenerative changes in proximal and distal parts of the damaged neuron. Some plants due to the antioxidant substances are effective in the survival and division of the neurons. This study aimed to investigate the effect of alcoholic extract of Salvia chloroleuca leaves on destruction of spinal cord anterior horn alpha motoneurons after sciatic nerve injury in rats. In this experimental study 24 male Wistar rats aged 12weeks and weighting 200-250gr were provided. The animals were divided into 4 (each=6) control, damaged, damaged + treatment with 50mg/kg alcoholic extract and damaged+treatment with 75mg/kg alcohol extract groups. To calculate the alpha motoneurons in the anterior horn of the spinal cord in the right side the dissector method was used. Data were analyzed using Minitab 13 software by independent T and ANOVA tests. The mean density of alpha motoneurons in spinal anterior horn in control group was 1711.5±47.4, in damaged was 730.7±33.4, in damaged+treatment with 50mg/kg alcoholic extract was 1211.2±34.8 and in damaged+treatment with 75mg/kg alcoholic extract was 987.4±36.8. Mean difference between both treatment groups and damaged group was significant (p=0.001). Salvia chloroleuca leaf extract increases the density of alpha motor neurons in the anterior horn of the spinal cord in rats with sciatic nerve injury, and this increase in neuronal density is associated with the intake of the extract.

Kawasaki disease (KD) is an acute multisystem vascular syndrome of unknown etiology that is the leading cause of acquired heart disease in children of developed counties.. We aimed to evaluate the epidemiological characteristics and clinical manifestations of KD in children residing in the southwest of Iran..Patients and In this retrospective study, we reviewed the medical records of all children with KD who had been admitted to the main children’s hospital of Ahvaz, southwest Iran, from March 2000 to March 2010. Data regarding clinical and epidemiological characteristics, management, and the outcome of disease for each patient were obtained. The patients were divided into cardiac and non-cardiac groups based on echocardiographic results.. In total, 104 patients with KD (66 boys and 38 girls) were enrolled in this study. The male to female ratio was 1.7:1. The mean ± SD age of the patients was 33.6 ± 24.2 months. Most (87.2%) cases were from urban areas. The disease occurred more frequently during winter and spring. Furthermore, 61.5% of the children had the criteria of classic KD, and 38.5% were labeled as incomplete KD. The mean ± SD of the duration of hospital stay was 6.9 ± 2.4 days. The mean time between illness and admission to the hospital was 6.47 ± 2.6 days. The most common sign was fever, followed by conjunctivitis and oral changes. In total, 20% of the patients had cardiac abnormalities. There was no significant statistical difference between the cardiac and non-cardiac groups according to age, sex, clinical manifestations, laboratory findings, and cessation of fever. The duration of hospital stay and the time between onset of illness and diagnosis were longer in the cardiac group. All patients received intravenous immunoglobulin and aspirin. Only one patient continued to have cardiac abnormalities after 6 months of follow-up.. Kawasaki disease is not rare in southwest of Iran. The age, gender distribution and clinical findings are similar to that of other reports. Patients with cardiac abnormalities had delayed treatment and prolonged hospital stays..

Advance progression in percutaneous coronary intervention (PCI) technique, particularly with new advanced drug eluted stents (DES) has made it an effective treatment for many cardiac diseases.

Redo coronary artery bypass surgery (CABG) has higher risk of mortality rather than first operation. Although the positive impression of percoutaneous coronary intervention (PCI) in such symptomatic patents has not proven yet, but different studies have evaluated the outcome of the symptomatic post CABG patients after performing PCI. In this study we aim to find out if PCI could be helpful in such patients. Patients and

In this study, 111 symptomatic patients with pervious history of single coronary artery bypass graft (without concomitant vale surgery) underwent PCI by a single operator between March 2008 and March 2012. Then, they were followed during the following year after PCI and the incidence of death redo CABG, persistent cardiac symptom and rate of hospitalization were recorded

The successful rate of PCI in this study was estimated to be 94.5% (104 of 111). In hospital MACE was 9.6% (three deaths and one myocardial infarction). 67% (73) of patients were male and 33% (33) were female. 79.6% (86) of PCI procedures were done on native coronary arteries and 20.4% (22) on SVG grafts. During one year follow up, we had 7 death in patients with PCI on native vessels (group A) and 1 death in the patients whose PCI was performed on SVG grafts (group B), (P ≥ 0.999). In group A, 27.9% (24) patients were remained symptomatic; while in group B, 18.4% (4) patients were still symptomatic (P = 0.353). Hospitalization because of cardiac syndrome was recorded for 10.5% (9) patients in group A and 9.1% (2) patients of group B (P > 0.955). None of the patients of group B went under redo-CABG during the follow up but 2.3% (2) patients of group A did (P > 0.289). No case of stent restenosis or target vessel revascularization was recorded in either group. The overall rate of death was 7.6% (8 0f 104), persistent cardiac symptoms 27% (28 0f 104), hospitalization for cardiac symptoms 10.5% (11 f 14) and redo CABG 2% (2 of 104).

This study shows that PCI in symptomatic post CABG patients follows by high successful and low complication rate and positive impression on their cardiac symptoms and could reduce the need for redo CABG. It seems that there is no difference that PCI is performing on SVG or native vessel, the intervention itself improves the patients’ quality of life.

Primary percutaneous intervention (PCI) is the choice of reperfusion therapy and is significantly superior to thrombolysis in acute ST-elevation myocardial infarction (MI).

We did design this study to evaluate the successful rate, early complication and late follow-up of the patients with acute myocardial infarction who referred to Razavi Hospital. Patients and

In this study, 68 consecutive patients who were admitted by diagnosis of acute coronary myocardial infarction and ST-elevation change in ECG underwent primary PCI by a single high volume operator from March, 2008 to March, 2011. The successful rate, incidence of in Hospital’s main adverse cardiac effects (MACE) and main adverse non-cardiac effects (MANE) and also their impact on one- year cardiac mortality and morbidity were estimated.

The successful rate of primary PCI in this study was estimated to be 100%. MACE occurred in 4 patients (5.8%) (2 deaths and 2 myocardial infarctions) and MANE occurred in 8 patients (11.8%) (7 cases with major or minor bleeding and one with contrast nephropathy). In one- year follow-up of patients who included in the study, surveillance rate was 91.2 % (62 of 68), 13 patients had persistent cardiac symptoms (19.1%), 3 of them were admitted to the hospital with coronary syndromes (4.4%) and just one patients underwent target vessel revascularization (1.5%). 3 patients had to do CABG in the first year (4.4%). Studying the long term MACE and stent type (drug eluting stents vs. bare metal stents) revealed: death; 1 (3.6%) vs. 6 (11.5%), persistent cardiac symp; 3 (10.7) vs. 11 (21.2%), hospitalization; no patient vs. 4 (7.7%) and no TVR in drug eluting stents (DES) group vs. 1 (1.9%) in bare metal stents (BMS) group.

This study confirms that Primary PCI revascularization is the best treatment for the acute ST elevation MI with brilliant acute result and one- year high survival and acceptable cardiac and non-cardiac complications. Studying the effects of using DES and BMS on long term cardiac mortality, morbidity and need to target vessels revascularization (TVR) shows that performing the PCI in the golden time is very important and type of stent is not much important. By reducing the expenses of this procedure through using BMS, we can give this chance to more patients.

Neurons are injured under physical, chemical and pathological conditions. The effects of injuries in peripheral nervous system return as retrograde to the cell body of neurons in central nervous system and cause brain and spinal degeneration. This study was done to determine the neuro-protective effects of aqueous extract of Salvia chloroleuca leaves on degeneration of alpha motoneurons in spinal cord after sciatic nerve compression in rats. This experimental study was carried out on 24 male Wistar rats. Rats were divided into four groups each consisting six members: control, compression, compression with treatment of 50 mg/kg aqueous extract, and compression with treatment of 75 mg/kg aqueous extract. In control group, muscle slitted without injury in the area of sciatic nerve. In compression group and treatment groups, the right leg sciatic nerves got through compression for 60 second. The first extract injection was done intraperitoneally immediately after compression and the second interaperitoneal injection was done 7 days later. 28 days after compression, the Lumbar spinal cord was dissected, fixed and stained with toluidine blue. After tissue processing, 7 micron serial sections stained with toluidine blue, the neurotic density in each group was compared with the compression group. The results indicated that neuronal density had a significant reduce in compression group and control group (P<0.001). Also, in treatment groups C and D, it had a significant increase compared to the compression group (P<0.001). The aqueous extract of Salvia chloroleuca has neuroprotective effect on spinal cord alpha motoneurons after injury. This could be due to growth and regeneration factors present in the aqueous extract of Salvia chloroleuca leaves that induce regeneration process in injured neurons and prevent degeneration intensity.

In a logistic system, decisions on location of depot, vehicle routing and assignment of routes to vehicles should be considered simultaneously. The location-routing problems are defined to find the optimal number and locations of depots, and at the same time with the distribution routes for the vehicles. Because of the complexity and the time consuming computation, this problem belongs to a class of combinatorial optimization and NP-hard problems. Finding an optimal solution for this type of complex, huge problem in reasonable computational time by using traditional and exact approaches and optimization tools is very difficult. So a Meta heuristic algorithm based on ant colony system is proposed to solve this problem. According to the experiments, this proposed algorithm reports near-optimal and promising solutions in reasonable time. Also in this paper the assumption of assigning several routes to a vehicle during its available time is considered. Finally, the computational results obtained by this algorithm are compared with the results reported by Lingo software.