فهرست مطالب maryam shakarami

Considering the high incidence and mortality rate of gastrointestinal cancers (GIs) worldwide and partial success of the current available GI cancer treatments, there is a necessity to discover more effective approaches in cancer therapy. The failure in conventional therapies seems to be related to the resistance of cancer cells to chemotherapy, inability to target tumor cells especially in metastatic cancers, deficient drug concentrations in tumor sites, and unfavorable effects on pivotal non-malignant bodily tissues following systemic administration. In this context, we need an appropriate carrier for the delivery of therapeutic agents specifically to the GI cancer site. Mesenchymal stem cells (MSCs), a prominent cell-based strategy for cancer treatment, overcome various cancer therapy limitations and could be used as vehicles to deliver many anticancer agents such as therapeutic genes (DNA or interference RNA), oncolytic viruses, and chemotherapeutic or nanoparticle drugs. Moreover, secreted molecules of unmodified MSCs lead to deregulation of several proteins and different signaling pathways eradicating cancer cells. In the present review, at first, we overview the characteristics and utility of MSCs in cancer therapy, secondly, we discuss the application of naïve MSCs and utilization of MSCs in the delivery of therapeutic agents in GI cancer therapy and, finally, more information about harnessing of genetically modified MSCs in GI cancer treatment will be presented.

The aim of this study was to investigate the effect of corrective feedback (written and verbal) of teachers in a formative evaluation of the learning love of first grade male students in the nith grade in Alashtar city, Iran.

This study was a quasi-experimental study in which the pretest-posttest control group was used. The sample consisted of 40 subjects selected by multistage cluster sampling method and were randomly assigned to experimental groups and control group. The data were collected from McFarllen Learning Love Questionnaire (2007). Data were analyzed using univariate analysis of covariance.

The results of one-variable covariance analysis showed that there was a significant difference between male and female students of experimental and control groups in terms of love for learning English (P <0.001, F = 24.58).

It can be concluded that written and verbal feedback of Butler and Wine-based model can be effective. If the teachers after the model of Butler and Wine’s formative assessment provide feedback to students, the level of Learning Love could be significantly increased.to students, they can study the level of Learning Love to significantly increase.

The aim of this study was to investigate the effect of feedback corrective teachers in a formative evaluation of the Resiliency Education and Meaning of education Khorramabad city was the first high school male students. this quasi-experimental study in which the pretest - posttest control group was used. The sample consisted of 40 subjects that among male high school students of Khorramabad selected by multistage cluster sampling method and were randomly assigned to experimental groups (written and verbal feedback Butler and Wine-based model) and control group were assigned. The intervention groups for 10 weeks after genetic evaluation model based on feedback received. During this period, the control group received no intervention. The data were collected from questionnaires meaning of education and resilience scale study in the pre-test and post-test for both test and control groups were used. Data were analyzed using multivariate analysis of covariance. Covariance analysis showed significant differences between the two groups. they come to significantly increase. Results showed that the level of academic resilience and Meaning of education experimental group was significantly increased compared to control group. they come to significantly increase. Thus If the teachers after the model of formative assessment Butler and Wine to provide feedback to students, they can study the level of resiliency and Meaning of education to significantly increase.

 Addiction nowadays has become one of the most serious problems of human society, which leads to the emergence of poverty and unemployment and, more importantly, the emergence of frequent occupational, social and legal problems.The main purpose of this study was to determine the effectiveness of behavior-dialog therapy in changing the level of negative and positive meta-cognitive beliefs among addicted in Khorramabad city. Work

 This quasi-experimental study was carried out using pretest-posttest design with control group. The research sample consisted of 40 subjects selected from among addicted men in Khorramabad city of Iran and randomly assigned to experimental (of cognitive group therapy) and control groups. At the intervention stage, the experimental group was trained in life-style therapy in 8 sessions. Metacognitive beliefs questionnaire was used for data collection in pre-test and post-test phases for both experimental and control groups. Data were analyzed using multivariate analysis of MANCOVA. 

 The results of covariance analysis showed a significant difference between the two groups (p <0.06). The findings indicated that the of cognitive group therapy of the health care system is effective in changing the level of positive and negative financial implications.

 Therefore, people who work in the field of combating drugs and treating people with addiction, use of cognitive group therapy, they can create metacognitive beliefs in patients.