فهرست مطالب neda fayazi

With age increases, the risk of cancer increases, and the importance of examining important sources of adjustment, including a sense of coherence, physical function, and social support to control the living conditions of these people, is of particular importance. Therefore, the present study was conducted to determine the relationship between a sense of coherence and physical function, and social support.

The present study is a correlational study that was performed on 120 elderly people with cancer by available sampling in selected hospitals of Shahid Beheshti University of Medical Sciences in Tehran. Data collection tools were a short cognitive test scale, sense of coherence, activities of daily living, instrumental activities of daily living, and social support questionnaires.

The results showed that the sense of coherence had a significant positive relationship with physical function in the field of instrumental activities of daily living and activities of daily living and social support, but social support did not have a significant positive relationship with the two variables of physical function. Also, the mean of a general sense of coherence was 15/28±54/88, physical function was 99/60±13/3 and 56/70±9/4 and social support was 78/96±61/14.

The results showed the sense of coherence was positively related to the two variables of physical function and social support. Since a sense of coherence can help improve the physical function and social support of the elderly with cancer, the need for strategies and interventions based on promoting a sense of cohesion by nurses and other clinicians is emphasized.

Malaria and cancer are two major health issues affecting millions of lives annually. Maltol complexes and derivatives have been extensively investigated as chemotherapeutic and antimalarial activities. In this study, the design, synthesis, biological activities, and docking study of a novel series of pyridinones derivatives were reported.

The chemical structures of synthesized compounds were approved by FTIR, 1 HNMR, 13 CNMR, and mass spectroscopies. The antimalarial activity was evaluated through β-hematin inhibition assay and the cytotoxicity activities were evaluated against PC12 and fibroblast cell lines via MTT and cell uptake assays. To theoretically investigate the ability of compounds to inhibit hemozoin formation, the synthesized compounds were docked in a heme sheet to explore their bi nding mode and possible interactions.

β-Hematin inhibition assay showed acceptable activity for 7f, 7c, and 7d compounds and the molecular docking study showed 7h and 7f had effective interactions with the heme sheet. The cytotoxic study revealed compound 4b (IC50 = 18 μM) was significantly more active against PC12 cells than docetaxel (IC 50 = 280 μM). The observations of cell uptake images were also shown both cell penetration and monitoring potential of synthesized compounds.

The compounds showed a moderate ability to inhibition of heme polymerization and also good interaction with heme through molecular docking was observed. Additionally, some of them have a good cytotoxic effect on the study2 cell line. So further study on these compounds can lead to compounds that can be considered as anti-malarial and/or anticancer agents.

Coronary artery disease is one of the most common cardiovascular diseases leading to disability and significant complications in patients. This also imposes burdens on families and societies. This study aimed to investigate the effect of self-care education on the life quality of patients with the acute coronary syndrome.

This clinical trial was conducted on 70 patients with coronary artery disease who were randomly divided into intervention (n=35) and control (n=35) groups. At the beginning of the study, both groups were asked to complete a 36-item Short Form (SF-36) survey of quality of life. Subsequently, the intervention group received three 30-45-min self-care training sessions with a one-day interval within a week. Immediately after the intervention and two months later, the patients completed the quality of life questionnaire. Finally, the data were analyzed in SPSS software (version 20) using independent t-test, Chi-square, and repeated measures analysis of variance.

The mean scores of quality of life were 45.35 and 45.62 in the intervention and control groups before training, respectively. Immediately after the intervention and two months later, the corresponding values were 66.34 and 64.81 in the intervention group, which showed a significant difference between the groups in this regard (P=0.01).

According to the results, self-care education can increase the quality of life among patients with coronary artery disease. Moreover, it can be used as one of the non-pharmacological and effective methods for the treatment of coronary artery disease.

Anxiety and its control is a public health problem worldwide. This study was conducted to determine the effect of family members’ presence on the anxiety level of patients who were candidates for esophagogastroduodenoscopy (EGD).

This randomized controlled trial study was performed in Shahid Chamran hospital in city of Saveh in IR Iran. In this study, 96 patients who were candidates for EGD and met the inclusion criteria were assigned into control and intervention groups by simple random sampling method. The demographic questionnaire and Spiel Berger's State and Trait Anxiety Questionnaire (STAI) were used to measure anxiety.

  No significant difference was found between the 2 groups in the mean level of anxiety before intervention (p=0.13). After intervention, the level of anxiety decreased significantly in the intervention group (p=0.001). However, the mean level of anxiety was not significant in the control group after intervention (p=0.09).

The results of the present study showed that the presence of family members during endoscopy may reduce the patient’s anxiety level, and thus it is recommended as a non-pharmaceutical, beneficial, and safe intervention.

The most important responsibilities of an education system are to create self-directed learning opportunities and develop the required skills for taking the responsibility for change. The present study aimed at determining the impact of a learning contract on self-directed learning and satisfaction of nursing students.
A total of 59 nursing students participated in this experimental study. They were divided into six 10-member groups. To control the communications among the groups, the first 3 groups were trained using conventional learning methods and the second 3 groups using learning contract method. In the first session, a pretest was performed based on educational objectives. At the end of the training, the students in each group completed the questionnaires of self-directed learning and satisfaction. The results of descriptive and inferential statistical methods (dependent and independent t tests) were presented using SPSS.

There were no significant differences between the 2 groups in gender, grade point average of previous years, and interest toward nursing. However, the results revealed a significant difference between the 2 groups in the total score of self-directed learning (p= 0.019). Although the mean satisfaction score was higher in the intervention group, the difference was not statistically significant.

This study suggested that the use of learning contract method in clinical settings enhances self-directed learning among nursing students. Because this model focuses on individual differences, the researcher highly recommends the application of this new method to educators.

Improvement in HIV care have resulted in prolonged life expectancy for HIV-positive persons, hence, identify preventive behaviors of HIV transmission in HIV-positive persons has not only become a necessity, but a main concern in HIV prevention. The aim of this study was to evaluate of beliefs and factors influencing preventive behaviors of HIV transmission in HIV-positive patients.
A descriptive-analytical study was conducted in two cities (Sarbaz and Saravan) in Sistan&baloochestan Province. Participants included 92 HIV-positive patients. Data were obtained anonymous self-reported questionnaires. Descriptive statistics, multiple logistic regression analyses were employed to identify factors associated with preventive behaviors of HIV transmission.
The 78% and 22% of subjects were male and female, respectively. The result indicated that all Health Belief Model construct were signifcant prediting facotrs for preventive behaviors. Inaddition, percieved barriers, self efficacy, benefit, severity, susceptibility were the most important predictor respectivly. Also, variable of educational level, marital status, perceived depression and anxiety, and social support were significant factors to preventive behaviors (p The present study showed that the HBM can be used to explain the predictors of behaviors in HIV-positive patients. . Future prevention interventions should be focused on the improvement in self-efficacy, the reduction in the barriers and the increasing perceived benefits of to preventive behaviors among HIV-positive patients.