rasul taghvaee far

The risk of bone fractures, particularly hip fractures is increasing in the elderly. One of the known factors for predicting fractures is body mass index (BMI) and abdominal obesity. Thus, this study aimed to determine the association between obesity (general and abdominal) with femoral and hip fractures according to gender and age.

In this descriptive cross-sectional study, 100 patients with femoral or hip fractures admitted to the orthopedic ward of Khatam Al-Anbia Hospital in Zahedan were selected between March 2018 and May 2019.  Waist circumference (WC), wrist circumference, BMI, and body size were measured. A P-value of <0.05 was considered as statistical significant. All the analyses were performed by SPSS software version 21.

The highest rate of hip fracture was observed in people aged over 70 years (61.9%, P < 0.01). The highest rate of hip and femoral fractures were observed in individuals with BMI < 23 kg/m2 (P < 0.001) and taller people (>167 cm) (P < 0.0001). The risk of fractures decreased with increasing WC (P < 0.01). Approximately half of those with hip fractures (52.4%) and femoral fractures (51.9%) had small size.

On the basis of our findings, taller height, lower BMI and smaller body size have been suggested as potential contributions to the risk of femoral and hip fractures. It is suggested that abdominal fat may be protective against the risk of hip and femoral fractures at older ages, which requires further research.

Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders in women of infertility. Women with PCOS are at high risk for early cardiovascular disease. The aim of this study was to evaluate the oxidative stress, inflammatory factors and other cardiovascular risk factors in patients with PCOS.

In this case-control study, 50 women with PCOS and 50 healthy women referred to Zahedan Infertility Clinic who were matched for age and BMI were selected by convenient  sampling method. Anthropometric parameters, biochemical tests, C3 and C4 complements, TAC and MDA levels were measured in all subjects. Data were analyzed using independent t-test and analysis of variance at the significant level P

Results showed that mean waist circumference (P = 0.048), systolic blood pressure (P <0.01) and diastolic (P = 0.048), serum LDLC levels (P = 0.05) and MDA (P <0.0001) were significantly higher in women with PCOS and serum HDL-C levels (P = 0.03) and TAC (P = 0.05) were significantly lower than   control group. Mean serum levels of C3 and C4 were higher in the PCOS group than in the control group, but this difference was only significant for C3 (P = 0.03) .

The findings showed that levels of dyslipidemia, oxidative stress and inflammatory factors were higher in PCOS women with abdominal obesity. Thus, screening of these factors and weight management, especially in obese women with polycystic ovary syndrome, is recommended in treatment strategy.