فهرست مطالب rouhollah akbari

Being overweight and having vitamin D deficiency are associated with oxidative stress and low-grade chronic inflammation, resulting in various diseases. In the present study, changes in the levels of Eutoxin-1 and superoxide dismutase (SOD) were evaluated after 8 weeks of high-intensity interval resistance training (HIIRT) and vitamin D intake in overweight women with vitamin D deficiency.

In this clinical trial study, 52 overweight women with vitamin D deficiency were purposefully selected and then randomly assigned to exercise, vitamin D, exercise+vitamin D (combined), and control groups. HIIRT was performed 3 times a week in three sets with an intensity of 80% of a maximum repetition. Vitamin D was taken at a dose of 50,000 units weekly. Data were analyzed using paired t-test, one-way ANOVA, and Kruskal-Wallis tests with a significant level of less than 0.05.

After 8 weeks, SOD activity increased in the experimental groups, and the level of Eutoxin-1 decreased significantly. In addition, the rate of changes in SOD and Eutoxin-1 levels in the combined group was higher than those in the vitamin D group; however, no significant difference was observed between the exercise and combination groups (P<0.05).

It seems that HIIRT and vitamin D intake can increase SOD activity and up-regulate Eutoxin-1 in overweight women. Moreover, co-administration of HIIRT with vitamin D intake can have stronger effects in reducing the inflammatory-oxidative effects of overweight and vitamin D deficiency by increasing SOD and decreasing Eutoxin-1, compared to the intervention of vitamin D consumption.

Overweight and obesity are associated with low-grade chronic inflammation, and the study of interventions affecting inflammation-reducing signaling pathways is a potential therapeutic goal in vitamin D (VD) deficiency-induced diseases. The aim of this study was to evaluate the effect of high intensity interval resistance training (HIIRT) and VD supplementation on Sirtuin 1(SIRT1) and Interleukin-10 (IL10) levels in overweight women.

This semi-experimental study was performed on 52 overweight women with VD deficiency (26.04±1.95 years and BMI=27.42±1.10 kg/m2). Subjects were purposefully selected and then randomly divided into exercise, VD, exercise +VD (combined) and control groups. HIIRT consisted of three sets with an intensity of 80% of one maximum repetition, and 150 seconds of rest between sets for 8 weeks. VD was taken weekly at a dose of 50,000 units. Data were analyzed using paired t-test, one-way ANOVA and Kruskal-Wallis at P<0.05.

After 8 weeks of VD supplementation, HIIRT and combined intervention, SIRT1 and IL10 levels increased significantly (P<0.001). In addition, there was a significant difference between the rate of changes in IL10 and SIRT1 levels in the combined group with the exercise (P=0.004 and P<0.001, respectively) and VD (P<0.001) groups and also in the exercise group with the VD supplement group (P=0.004 and P=0.008, respectively).

It seems that HIIRT is more effective in increasing SIRT1 and IL10 and thus reducing inflammation and its complications in overweight conditions with low VD status, so that concurrent exercise interventions and VD consumption is associated with reinforcement these effects.

 The prevalence of overweight and sedentary lifestyle is one of the major health problems in the world that are associated with oxidative stress and vitamin D deficiency. In the present study, the effect of eight weeks of high intensity interval resistance training (HIIRT) on Sirtuin 1 and 25-hydroxyvitamin D levels in overweight women with vitamin D deficiency was investigated.

 This is a quasi-experimental study that was carried out on 26 overweight young inactive women with vitamin D deficiency. Subjects were selected accessibly and purposefully and then randomly assigned to the intervention and control groups (13 in each group). The main exercise consisted of three sets with 2.5 minutes rest between sets. Each set started with 6 repetitions at an intensity of 80% one repetition maximum and continued with another 20 seconds rest until exhaustion (2 or 3 subsequent repetitions). Data were analyzed by independent t-test and one-way analysis of covariance (ANCOVA) at the significant level of p<0.05.

 HIIRT intervention led to a significant increase in Sirtuin 1, 25-hydroxyvitamin D levels as well as superoxide dismutase activity in overweight women with vitamin D deficiency.

According to the results of the study, HIIRT as a non-pharmacological intervention can exert some of its supportive effects in overweight conditions with vitamin D deficiency, by improving the status of vitamin D and enhancing antioxidant defense from the Sirtuin 1/ superoxide dismutase pathway.

The word makr, often connected to Persian negative concepts such as deception, plot, betrayal, trick, hat, and deceit, in the Qur’an and Arabic literature has numerous meanings and more extensive functions, i.e. “any kind of thinking, caring and solution”, whether it be in good or evil deeds. In the Holy Qur’an, both applications have their own evidences; makr in good deeds is regarded as “praised makr” and in evil deeds is regarded as “disgraceful makr”, which the latter is said to be “makr l-sayyi'” in Qur’anic terms. The present research aims to survey some of the disgraceful practices of makr in the Qur’an, based on the descriptive-analytical method.

Job stress can impose significant costs to the workplaces and organizations due to some issues such as absenteeism, less productivity, and medical costs. Job overload and lack of decision latitude can lead to job stress. The current study aimed to investigate the job demands and control as predictor of job stress and its relationship, with some of the demographic characteristics of Iranian prison staff.

This study was performed on 171 male employees working in four prisons located in Ilam, Iran. The sampling method was census and all four prisons’ staff were selected to respond the Job Content Questionnaires. Finally, the data were analyzed using t‑test or independent samples test as well as SPSS 20.

The highest amount of job demand (mean = 21.28) and the lowest amount of job control on average (9.76) were reported by those staff working in Darehshahr prison. There was also a significant relationship between job post and job control among the prison staff (β = −0.375, P = 0.001).

The level of job stress reported by prison staff was high in this study mainly caused by high job demand and low job control, especially in Darehshahr prison staff.