sa taghavi
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Aims
In the field of infertility treatments, intrauterine insemination (IUI), with or without ovulation stimulation, is considered the first line of intervention. This study aimed to assess the relationship between various factors and the rates of biochemical and clinical pregnancy following IUI treatment over a five-year period.
Instrument & MethodsThis cross-sectional study was conducted at Kashan, Iran, 2023. The medical records of patients diagnosed with infertility and treated with IUI at the infertility center in Kashan were reviewed. The primary outcomes were biochemical and clinical pregnancy rates, along with associated factors. Data were analyzed using the Chi-square test and independent t-tests, with statistical significance set at p≤0.05.
FindingsA total of 334 patients were included in the study. The mean age of those with positive biochemical (p<0.006) and clinical pregnancy outcomes (p<0.008) was significantly lower compared to those who did not achieve pregnancy. A significant correlation was found between endometrial thickness and both biochemical (p<0.002) and clinical pregnancy rates (p<0.007). However, no significant associations were observed between the other variables and pregnancy outcomes.
ConclusionIncreasing maternal age is associated with a decline in biochemical and clinical pregnancy rates. In contrast, an increase in endometrial thickness positively correlates with higher biochemical and clinical pregnancy rates.
Keywords: Ovarian Stimulation, Pregnancy Rate, Infertility, Clinical Pregnancy -
Short Term Outcome of Patients with Hematochezia and Normal Initial Colonoscopic Findings: Do They Really Need Further Screening?BackgroundIn a significant number of the patients with hematochezia, colonoscopy turns out to be normal and therefore is unable to determine the cause of bleeding. This study investigates outcomes and possible necessity for further work up in cases of hematochezia with normal colonoscopy..MethodsNinety-seven patients with normal colonoscopy were followed for at least one year from the time of colonoscopy by regular visits and phone calls. Mortality and recurrent bleeding were recorded as primary end points. Those with recurrent or continued hematochezia were invited for a new visit and further work up..ResultsAmong the ninety seven patients, nine cases (9.3%) were lost at follow ups, 10 experienced rebleeding (10.3 %), and the remaining 78 (80.4 %) were apparently healthy and had no further complaints. There were two mortalities during the follow up, one due to gastric cancer and the other due to cerebrovascular accident..ConclusionIt is unusual for the cases of hematochezia with a normal initial colonoscopy to have recurrent bleeding as a result of a significant missed lesion in the colon.
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Ba ckground The only curative therapy for end-stage liver disease is transplantation but due to a shortage of available donor livers the waiting list mortality is high. This study aimed to evaluate the outcome and characteristics of patients on the waiting list for liver transplantation in Shiraz, southern Iran during the period from April 2004 to March 2007. Methods Medical records of all chronic liver disease patients ≥14 years that were on the waiting list for liver transplantation at the Nemazee Hospital Organ Transplant Center during April 2004 to March 2007 were reviewed. Hospital records were used to retrieve demographic, clinical and laboratory data. Records of the referring gastroenterologists provided information about the etiology and complications of liver disease. The patients were followed at the end of the study period by clinic visits or telephone contact. R esults There were 646 patients on the waiting list for liver transplant during April 2004 to March 2007. Hepatitis B was the most common etiology of liver disease (31.2%). Of those on the waiting list, 144 patients 22.3%) underwent liver transplant and 166 (25.7%) died while waiting for a transplant. The mean waiting period for transplant was 6.6 months. Receiving a transplant was correlated with the etiology of liver disease and Rh blood group (p<0.05) but had no significant association with gender or ABO blood type. Among non-transplanted patients, survival was lower in those who had a history of encephalopathy, SBP or uncontrolled ascites and in patients with a Child-Turcotte-Puph (CTP) class C and/or a Model of End-stage Liver Disease (MELD) score≥15. C onclusion Hepatitis B virus is the most common cause of end-stage chronic liver disease amongst patients on the waiting list for liver transplant in Shiraz, southern Iran. Patients with a MELD score≥15 particularly those with a history of SBP, hepatic encephalopathy or uncontrolled ascites are recommended for waiting list enrollment.Keywords: Liver transplant, Waiting list
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