Comparing the Rate of Chemical Pregnancy and Clinical Pregnancy after IUI Treatment According to Some Factors

In the field of infertility treatments, intrauterine insemination (IUI), with or without ovulation stimulation, is considered the first line of intervention. This study aimed to assess the relationship between various factors and the rates of biochemical and clinical pregnancy following IUI treatment over a five-year period.

This cross-sectional study was conducted at Kashan, Iran, 2023. The medical records of patients diagnosed with infertility and treated with IUI at the infertility center in Kashan were reviewed. The primary outcomes were biochemical and clinical pregnancy rates, along with associated factors. Data were analyzed using the Chi-square test and independent t-tests, with statistical significance set at p≤0.05.

A total of 334 patients were included in the study. The mean age of those with positive biochemical (p<0.006) and clinical pregnancy outcomes (p<0.008) was significantly lower compared to those who did not achieve pregnancy. A significant correlation was found between endometrial thickness and both biochemical (p<0.002) and clinical pregnancy rates (p<0.007). However, no significant associations were observed between the other variables and pregnancy outcomes.

Increasing maternal age is associated with a decline in biochemical and clinical pregnancy rates. In contrast, an increase in endometrial thickness positively correlates with higher biochemical and clinical pregnancy rates.