فهرست مطالب saber saedmocheshi

Lifestyle modification is an important aspect of preventing various diseases, including various types of cancer. The aim of the present study was to investigate the effect of eight weeks of aerobic training and green tea extract on NF-κB, COX-2 and suppressor protein of p53 in prostate tissue of healthy rats.

Materials & Methods:

32 male Wistar rats were randomly divided into four groups: green tea extract, exercise training, green tea extract + exercise training, and control. The exercise training program included aerobic training on a low to moderate intensity on the treadmill (at a speed of 3-10 m/s, 3 sets of 15 min with 2 min of rest between sets, 5 days a week). Green tea extract was gavaged at a dose of 1.3 ml of solution at a concentration of 10 mg/100 ml (3 sessions per week). Scarify was performed 48 hours after the end of the intervention. The results were analyzed using parametric statistical methods of analysis of covariance and one way ANOVA.

Aerobic training significantly increased NF-κB level compared to the control group (P = 0.02). The combination of aerobic training and consumption of green tea extract did not significantly change the level of NF-κB. The COX-2 and p53 levels were not significantly different after aerobic training and green tea extract (P > 0.05).

Green tea supplementation seems to modulate NF-κB level following aerobic training, which can reflect the anti-inflammatory effects of green tea and its role in preventing prostate cancer.

lack of mobility has an important role in the development of obesity in the elderly population. The purpose of this study was to investigate the effect of regular aerobic exercise and omega-3 supplementation on serum levels of CRP and IL-6 in elderly women were obese.

In a double-blind study, 40 obese women (BMI ≥ 30) 61.65±7.42 years old were selected as easily-accessible way and randomly categorized into 4 groups of 10 subjects an exercise, supplementation, exercise – supplementation (combination), and placebo (control) groups. Subjects in the supplement and combination groups consumed 2080 mg omega-3 supplement daily for 8 weeks and control groups used sunflower oil as placebo produced in Zachariah Company. Exercise program included aerobic activity at 45 to 55 percent of maximum heart rate for 8 weeks, 40 minute and 3 sessions per week. Blood samples before and 24 hours after the training period in the fasting state were collected. Data analysis was done by paired-t test and two-way ANOVA test using SPSS software (version 16).

Statistical test results showed that the concentration of IL-6 and CRP were significantly decreased in the groups of exercise with supplements (p<0/05).

The result of this study, carried out 8 weeks of aerobic training with omega-3 supplementation improves the inflammatory status Caused by exercise training combined with omega 3.

During the military service, soldiers suffer from fatigue and reduced motivation. The purpose of this study was to compare the effect of chronic and acute sodium bicarbonate supplementation loading along with exhaustive work on the performance and fatigue indicators of soldiers.
In this study, 30 soldiers were divided into a semi-experimental design into two groups (control, intervention). The control group received dextrose (% 0.02) and the intervention group consumed two methods of chronic loading (0.5 g/kg) and acute (0.3 g/kg) sodium bicarbonate supplementation. In order to calculate the chemical variables (bicarbonate, lactate, PH), blood samples were taken before and after the exercise test and one hour later. The exercise test for Wingate test was used to assess the subjects.
Results reveal that the level of the acidity of the blood with chronic sodium bicarbonate supplementation has led to the alkalization of the blood and fatigue to be postponed. The results showed that the use of bicarbonate in the acute and chronic loading led to an improved excretion of the lactate.
Due to the buffering properties of sodium bicarbonate supplementation and delaying the time to fatigue and improve performances, chronic loading for short and severe activities in soldiers and even athletes can be recommended.

The use of antioxidants before high-intensity training, which leads to the release of free radicals and muscle injuries, can result in reduced damage during exercise. Accordingly, in this study, we aimed to evaluate the effect of selenium supplement intake on oxidative stress, following exhaustive aerobic exercise among young physically-active females.
In this quasi-experimental study, 20 healthy girls (age: 23.6±1.5 years, height: 1.61±0.0126 m, and weight: 60.2±7.13 kg) were randomly divided into exercise (n=10) and supplement exercise (n=10) groups. The participants were asked to consume selenium supplements (200 µg/day) for a period of 14 days. The Bruce protocol stress test was conducted 24 h after the final intake of supplements and primary blood collection (in a fasting state). Also, immediately after performing the Bruce test, the second blood samples were drawn from the subjects. Oxidative stress markers (i.e., creatine kinase, lactate dehydrogenase, and malondialdehyde levels) were measured at each stage of blood sampling and were compared between the groups using paired t-test. Data analysis was performed by SPSS (version 18). P-value less than 0.05 was considered statistically significant.
The results indicated that exhaustive aerobic exercise could cause a significant increase in creatine kinase, lactate dehydrogenase, and malondialdehyde levels. The comparison between the control and intervention groups suggested the significant effect of selenium supplementation on declining of lactate dehydrogenase level (P The results of the present study demonstrated that selenium supplements could reduce oxidative stress, induced by exhaustive physical exercise.

To investigate the effects of sodium bicarbonate (NaHCO3) on exhaustive activity and physiological parameters of fatigue in conscripts. Thirty conscripts did Wingate test in two groups: sodium bicarbonate group (treatment) and placebo (control) group. In both groups, sodium bicarbonate (0.3 g/kg of body mass) or placebo was ingested 60 minutes before the training in 250 mL solution. Blood sample was collected before and after doing Wingate test. All parameters were compared using two-way analysis of variance (ANOVA), followed by Tuke y’s post-hoc test. Significance level was set at. 05. After sodium bicarbonate supplementation, the La Anion in Wingate test was significantly higher in the treatment group than the control group (17.93 ± 3.8 mmol/L vs 15.67 ± 3.29 mmol/L P <. 01). Sodium bicarbonate supplementation had no significant effect on heart rate in both groups. Sodium bicarbonate improves conscripts’ performance by increasing glycolytic capacity but does not improve fatigue indicators.

Cardiovascular diseases, especially atherosclerosis are the main cause of death worldwide which its prevalence is increasing in Iran as well. The present study examined the effect of grape seed supplement and aerobic activity on cardiovascular risk in elderly women. In a double-blind study, 24 obese women (BMI≥30), 55 to 65 years old were randomly divided into two groups of exercise with supplement (12 individuals) and exercise (12 individuals). Aerobic training program was performed 1 hour per session, 3 sessions per week during 8 weeks (with 45 to 55 percent of maximum heart rate). A daily dose of 200 mg grape seed extract was used for 8 weeks in supplement group. Blood samples were collected before and 48 hours after the last session of the study (12h fasting). Dependent t-test and independent t-test were used to compare data before and after the study and for comparison between two groups respectively. Data showed a significant difference in amount of homocysteine, hs-CRP, cholesterol, triglyceride and LDL-C between pretest and posttest of supplement group, while there was no difference in any variable in the control group. According to the present study, 8 weeks aerobic exercise and consumption of grape seed extract can prevent atherosclerosis and improve public health. Also it may control and reduce atherosclerosis in obese individuals.

Hyperlipidemia is a major cause of cardiovascular diseases (CVD) and the most common problems in the community. The present study examined the effect of grape seed supplementation along with aerobic activity on lipid profile in elderly women. In this experimental study, 40 obese women (BMI≥30 kg/m2) over 60 years were selected and randomly divided into two groups (supplement + Exercise and control group). The exercise program included aerobic exercise with 50% of maximum heart rate for three times a week for 8 weeks plus Grape seed extract supplement 200 mg daily for 8 weeks. Blood sampling after fasting period for 12 hours in pretest and 48 hours after the last training session was taken. To compare data between groups t-test was used. The results showed significant differences in the levels of cholesterol, triglycerides and LDL-C and pre-test and post-test group supplemented along with sports activities. Long-term aerobic exercise combined with grape extract consumption may reduce the lipid profile parameters.

Exercise whole-body vibration by affecting the muscular system, increases the strength of the muscular system. This study was designed to investigate the effects of vibration on muscle performance in healthy, untrained, oldery men. in this randomized controlled trial semi experimental study seventy-two retired elderly men with a mean age of 67/2 ± 73 years were participated. The subjects were divided into three groups based on BOSCOO training plan and training was 6 weeks. Muscular function after training protocol with the test standard sit-to-stand and 5m fast walk was evaluated. Test sts after three sessions a week whole body vibration exercise as a significantly muscle was better than the other groups (p <0.05). The whole body vibration training three sessions a 5m fast walking performance significantly was better (p <0.05). The whole body vibration training can affect the nerve – muscle system especially in elderly population and have Reduce the possibility of falling.

Excessive physical exercise overproduces reactive oxygen species. Even if elite sportsmen increase their antioxidant status by regular physical training, this improvement is not sufficient to limit free radical production during the competition period which can be detrimental to the body. This study evaluates the effect of grape seed supplementation along with aerobic exercise on lipid profile in elderly women.

In a double-blind study, 40 obese women (BMI≥30) upper 60 years old were randomly selected and divided into two groups of experimental (10 individuals) and control (10 individuals). The experimental group received 2 GE supplementation (100mg·d1) for 4 weeks. Exercise program included aerobic exercise activities at 45 to 60 percent of maximum heart rate for 4 weeks and three 60-minute sessions per week. Blood samples were collected after 12 hours fasting before the study and 48 hours after the last session of the study. One-way ANOVA followed by LSD test was used for the statistical analysis.

The results of the present study shows that there is a significant difference among amount of cholesterol, triglyceride and LDL-C before and after the study, but these amounts were not significant in the control group.

According to the present study results, 4 weeks aerobic exercise can prevent atherosclerosis and improve people’s health and it can control and reduce atherosclerosis in obese individuals.

The purpose of this study is to examine the effect of whole body vibration on improvement of performance of patients with Multiple sclerosis. In this study, 73 patients with MS a mean age of 73±2.63 years participated, out of which 20 patients took part with complete satisfaction. They had average disability ranging from 2.05 to 4.5. The subjects were divided into four groups based on Bosco plan: 1 control group and 3 experimental groups. The 1st group did their job in 6 sessions and within 6 weeks. The 2nd group did their job in 12 sessions and within 6 weeks and the last group in 18 sessions and within 6 weeks. The Vibration frequency was 15-25 Hz. Having finished the exercise, the neuromuscular function was assessed with the standard 5-chair and TUG test. In order to analyze the data,SPSS version 18 was used in level of significance of α=5. The results of repeated measures analysis of variance and one-way analysis of variance showed that the whole body vibration exercise significantly decreased the time of 5-chair test (P<0.03) and tug test (P<0.03). The 5-chair test with three sessions a week training exercise had significantly better neuromuscular function than the two other groups (P<0.04). Whole-body vibration exercises in people with MS disease results in improvement of neuromuscular function.

Whole body vibration training can improve muscular force by affecting neuromuscular system and mechanical mechanisms. The aim of this study was to investigate the effect of an 8 week whole body vibration training (WBVT) on neuromuscular performance in healthy elderly women. Based on an experimental and BOSCO training protocol، thirty elderly female women (50±5. 5 yrs old) were selected and divided randomly into two experimental and control groups. Before and after vibration training، timed Up & Go and 5-chair stand tests were performed to evaluate neuromuscular performance in elderly women. Data were processed with SPSS software version 18 and one way ANOVA test was used for data analysis. P<0. 05 was considered significant. Data analysis showed that there was a significant improvement in neuromuscular performance in WBVT group compared to control group (P ≤ 0. 05). Based on the results of this study WBVT can reduce the possibility of falling risk among old women by improving neuromuscular performance.

Backgrounds and Approach of supplementation usage and its effect on fatigue retarding had been attention of athletes and coaches. The aim of this study was to comparison the acute and chronic loading of sodium bicarbonate supplement on fatigue and performance indices after exhaustive aerobic activity in active men. 10 active men were selected and assign to experimental group. The participants had taken sodium bicarbonate supplement in two forms of acute and chronic loading. For determine the amount of lactate production and blood PH، blood samples were taken in four stages including’s before exercise and after either supplementation method usage and also immediately after exercise test. Modified BRUCE moderate-intensity test were done up to 75% of maximum heart rate as exercise test. The result showed that bicarbonate supplement in form of chronic loading inhibits blood lactate accumulation significantly. Compared with acute model، chronic loading of sodium bicarbonate increased the duration of activity and blood PH up to 26 percent (P<0/05). It seems that chronic loading of sodium bicarbonate by improving the buffering capacity increase the amount of blood PH and retarding the fatigue period and induces the much time of activity.

Supplementation usage approach and its effect on fatigue retarding had been focused on by athletes and coaches. The aim of this study was to compare the effect of two acute and chronic loading of sodium bicarbonate supplement on Lactate and Inflammatory indices after exhaustive aerobic activity in active men. 10 active men were selected and assigned to experimental group. The participants consumed the supplement in two forms of acute and chronic loading of sodium bicarbonate. To determine the amount of lactate and blood CRP، blood samples were taken in four stages of prior to exercise test and after two form of supplement usage and also immediately after both exercise test. Modified BRUCE moderate-intensity test were done up to 75% of maximum heart rate as exercise test. The results showed that the consumption of bicarbonate in the form of chronic loading inhibited blood lactate accumulation significantly. Also in comparison with acute model، chronic loading of sodium bicarbonate increased the duration of activity (P<0. 05). The consumption of bicarbonate in the form of two loading models had no significant effect on C-reactive protein (P>0. 05). It seems that chronic loading of sodium bicarbonate due to improvement of buffering capacity increases retarding of fatigue period and lengthens the time of activity.