sareh karimi

Civil engineering is one of the oldest and most extensive engineering professions. The aim of this study was to analyze the descriptive and content structure of scientific productions of Iranian researchers in the field of civil engineering in the Web of Science (WoS) during 2013-2022.

The statistical population of this quantitative, applied, descriptive and analytical study consisted all scientific productions of Iranian scientists in the field of civil engineering in WoS during the years 2013-2022. This study was carried out by the scientometric method, using VOSviewer software to draw scientific maps and Excel and SPSS software to analyze the data. The Kolmogorov-Smirnov test was used to determine whether the data were normal or not, and the research hypotheses were tested with the Spearman correlation coefficient.

Most documents were published in 2021. Totally, 99.9% of the documents are written in English. The leading Iranian authors in this field are Ali Kaveh with the highest number of scientific productions (188), Mehdi Shariati with the highest number of citations (4917 citations) and Omid Bozorg-Haddad with the highest total linkage strength (230). Optimization (total linkage strength=689) was the most important in the network and the degree of centrality. There was also a significant relationship between the number of documents and the number of citations of the participating universities/organizations in the production of scientific documents in the field of civil engineering in the WoS (p< 0.001).

There was a significant relationship between the number of documents and the number of citations of Iranian authors in the field of civil engineering in the WoS. Moreover, Islamic Azad University is located in the center of the density map of the co-authorship network of universities and institutions in the field of civil engineering, indicating the importance of this university in the co-authorship network of institutions.

Health literacy includes skills required to make informed personal and social health decisions. Due to the increasing importance of health literacy, it is vital to investigate the quantitative and thematic publication process in this field. This study aims to investigate the publication process and draw a scientific map of articles in health literacy.

The current research is a descriptive-analytical one. Scientometric techniques were used for anlayzing health literacy publications from 2012 to January 23, 2023 in the PubMed database. RStudio and VOSviewer software were used for data analysis.

In the 12 years under review, 8,242 documents in the field of health literacy have been published. 27,193 authors and 1,588 journals contributed to the publication of these documents. Seven hundred four authors contributed to single-author papers, and 26,489 contributed to multi-author papers. International participation in this area was 11.95%. Wolf MS, Osborne RH, and Paasche-Orlow MK are the most contributing health literacy researchers. America-China registered the most scientific cooperation pairs. The International Journal of Environmental Research and Public Health has published the most health literacy articles among the journals. The research trend in 2013-2014 was toward teaching and educational principles and methods.

Researchers in the field of health literacy pay special attention to the issue of scientific cooperation. In the reviewed articles, COVID-19 is one of the prominent topics that coincide with the issue of health literacy.

Methamphetamine (METH) is a psychostimulant that has harmful effects on all organs,  the nervous system, cardiovascular system, and reproductive system. Since many METH consumers are young people of reproductive age, it poses a risk to the next generation of METH consumers. METH can pass through the placenta and is also secreted into breast milk. Melatonin (MLT) is the primary hormone of the pineal gland that regulates the circadian cycle, and it is also an antioxidant that can mitigate the effects of toxic substances. This study aims to investigate the protective effect of melatonin against the detrimental effects that METH has on the reproductive system of male newborns, whose mothers consumed METH during pregnancy and lactation. In the current study, 30 female adult balb/c mice were divided into three groups: control group, vehicle group that received normal saline, and the experimental group that received 5 mg/kg METH intraperitoneally during gestation and lactation. After lactation, the male offspring of each group were randomly divided into two subgroups, one of which received 10 mg/kg melatonin intragastrically for 21 days (corresponding to the lactation period of the mice) (METH-MLT) and the other did not (METH -D.W). After treatment, the mice were sacrificed and testicular tissue and epididymis were obtained for the following tests. The diameter of seminiferous tubules, SOD activity, total Thiol groups concentration, catalase activity, sperm count, and PCNA and CCND gene expression were significantly increased in the METH-MLT group compared with the METH-DW. Apoptotic cells and MDA level ameliorated in the METH-MLT group compared with METH-D.W, and testicular weight had no notable change. The current study represents that consumption of METH during pregnancy and lactation can have adverse effects on the histological and biochemical factors of testis and sperm parameters of male newborns,  which can be mitigated by taking melatonin after the end of the breastfeeding period.

Nowadays, methamphetamine (METH) abuse as a psychotropic drug is increasing. There is insufficient information about its adverse effects on the ovarian reserve of the next generation. Herein, we tried to investigate the effect of METH abuse during pregnancy and lactation and, subsequently, the therapeutic effect of melatonin on ovarian reserve in offspring.

In the present study, BALB/C pregnant female mice were divided into 3 groups: Control, Saline, and METH (5mg/Kg). METH was injected during pregnancy and lactation, and the female offspring of each group was divided into 2 subgroups: A) treated with 10 mg/kg Melatonin daily until puberty (6 weeks old) and B) received distilled water. The animals were sacrificed at 6 weeks of age, and blood samples were collected for hormonal assessments; the right ovaries were removed and fixed for TUNEL and Hematoxylin & Eosin staining, and the left ovaries were removed and stored for gene expression and oxidative stress evaluation.

In the MTEH group, two indicators of ovarian reserve (including anti-Müllerian hormone (AMH) and primordial follicle, and Cyclin D1 (CCND-1) and Proliferating Cell Nuclear Antigen (PCNA) genes expression significantly decreased, and the oxidative stress and apoptosis significantly increased in comparison with other groups. After lactation in the MTEH group, melatonin treatment significantly improved the ovarian reserve and gene expression and declined apoptosis and oxidative stress.

METH abuse during pregnancy and lactation decreased ovarian reserve in offspring. The administration of melatonin as an anti-oxidant agent after lactation can counteract the adverse effects of METH on offspring ovaries.

Purpose of the study:

This study aims to determine the effect of query expansion on the scientific texts retrieval in Persian.

The present study was conducted using quasi-experimental method. The results are the obtained by analyzing 40 initial and expanded queries of postgraduate students in the Faculty of Management, University of Tehran. Query expansion was performed manually using primary research results.

Query expansion of Persian scientific texts leads to an increase in the number of related retrieved documents, as well as the comprehensiveness and accuracy of retrieving scientific data in Elmnet search engine, which as a result, improves the overall performance of information retrieval.

Nowadays, automatic query expansion is on the agenda of databases. Given that Persian databases are not fully developed, and the existence of specific problems of writing in Persian language, information literacy training and the method of defining and expressing information requirements and providing them to the information retrieval systems, can have significant impact for postgraduate students and researchers, to retrieve the required information and save them time and money.

Electromagnetic field (EMF) emitted by mobiles may affect the male reproductive system. Selenium, as an antioxidant, may protect against electromagnetic field-induced tissue damage. Theis study aimed to investigate the effects of selenium on rat testis exposed to electromagnetic fields.

Twenty-four male Wistar rats were divided into four groups, namely EM group (2100 MHZ), EM/SE group (2100 MHZ + selenium (0.2 mg/kg), SE group (selenium 0.2 mg/kg), CONT (control group). Serum LH, FSH, testosterone, leptin and aromatase levels, testis weight and volume index, sperm parameters (count and abnormal percent), seminiferous tubule diam eters, germinal epithelia thickness, immunoreactivity of leptin receptor and caspase-3 (for apoptotic cells in germinal epithelium) were investigated.

Our results showed that serum LH, FSH, GnRH, testosterone level, sperm count, germinal epithelium thickness, and seminiferous tubule diameter were significantly declined in the EM group compared with the CONT group (P<0.05). However, in the EM group, the serum leptin level, sperm abnormality, aromatase enzyme level, apoptotic cells, and leptin receptor were increased compared with the CONT group (P<0.05). Furthermore, an increase in sperm count, germinal epithelium thickness, seminiferous diameters, serum LH, FSH, and GnRH, and testosterone levels, and a significant decrease in sperm abnormality, leptin receptor and apoptotic cells in the EM/SE group compared with the EM group were also observed (P<0.05).

This study showed that electromagnetic radiation may have detrimental impacts on the male reproductive system, which can be prevented by use of selenium.

The ample of studies show that Adriamycin caused hepatotoxicity in rat. The present study investigated the effects of Nigella Sativa (N. Sativa) and combination with Curcuma longa (C. longa) extract on Adriamycin-induced hepatotoxicity in rat. Rats were divided into eight experimental groups: Control (CO), Adriamycin (ADR), Vitamin C (Vit C), Adriamycin with Vitamin C (ADR嘫), N. Sativa with and without Adriamycin (NS 4, NS -ADR), Combination extract of C. longa and N. Sativa with and without Adriamycin (NSࢿ耍, NSADR). Malondialdehyde (MDA) and thiol levels and also the activities of catalase (CAT) in liver tissue were evaluated. MDA level in the liver tissue in ADR was increased compared to CO group but in NS4 group, ADR嘫 and NS –ADR groups decreased compared to ADR group. Thiol levels in ADR and ADR嘫 groups were decreased compared to CO group. Thiol levels in treatment groups were increased compared to ADR group. The activities of CAT in liver tissue of ADR group were lower than CO group, and increased in treatment groups comparison with ADR group. The results showed that chronic administration of N. sativa hydroalcoholic extract in Adriamycin-induced hepatotoxicity rats could decrease the oxidative stress injuries in liver tissue.

Regarding the anti‑oxidative effects on the central nervous system, the possible protection against brain tissues oxidative damage as a possible mechanism for improving effects of low doses of estradiol on scopolamine‑induced learning and memory impairments was investigated in ovariectomized (OVX) rats.

The OVX rats treated by (1) vehicle, (2) scopolamine, and (3–4) scopolamine plus estradiol (20 or 20 or 60 μg/kg). Estradiol was administered (20 or 60 μg/kg, intraperitoneally) daily for 6 weeks after ovariectomy. The rats were examined for learning and memory using passive avoidance test. Scopolamine (2 mg/kg) was injected 30 min after training in the test. The brains were then removed to determine malondialdehyde (MDA) and thiol contents.

Scopolamine shortened the time latency to enter the dark compartment in (P < 0.01). Compared to scopolamine, pretreatment by both doses of estradiol prolonged the latency to enter the dark compartment (P < 0.01). The brain tissues MDA concentration as an index of lipid peroxidation was decreased (P < 0.05). Pretreatment by estradiol lowered the concentration of MDA, while it increased thiol content compared to scopolamine (P < 0.05 and P < 0.01).

These results allow us to suggest a protection against brain tissues oxidative damage as a possible mechanism for improving effects of low doses of estradiol on scopolamine‑induced learning and memory impairments in OVX rats.

The aim of the study was to investigate the effects of Curcuma longa (C. longa) extract on Adriamycin-induced hepatotoxicity in rat.
Animals were divided in six groups: Control (CO), Adriamycin (ADR), Adriamycin with Vitamin C (ADR嘫), Vitamin C (Vit C), C. longa with Adriamycin (CL4) and without Adriamycin (CL-ADR). Hepatotoxicity was induced by Adriamycin 5mg/kg and rats were treated with C. longa 1000 mg/kg and Vitamin C 100 mg/kg , per day, orally for 4 weeks.
In the liver tissue of ADR group, Malonyldialdehyde (MDA) level was increased significantly compared to CO group, (p The results showed that chronic administration of C. longa hydroalcoholic extract in Adriamycin-induced hepatotoxic rats could decrease the oxidative stress injuries in the liver tissue.

Inflammation and oxidative stress is considered to have a crucial role in induction of nephropathy. Curcuma longa (C. longa) and Nigella sativa (N. sativa) have anti-inflammatory and antioxidant effects. This study was designed to investigate the effect of mixed hydro-alcoholic extract of N.sativa and C. longa on the oxidative stress induced by Adriamycin (ADR) in rat kidney. The animals were divided into 6 groups: control (CO), ADR, Adriamycin+ Vitamin C (ADR+VIT C), C. longa extract+ Adriamycin (C.LE+ADR), N. sativa extract+ Adriamycin (N.SE+ADR) and C. longa extract+ N. sativa extract + Adriamycin (N.S+C.L+ADR). ADR (5mg/kg) was injected intravenously, whereas VITC (100mg/kg) and extract of C. longa (1000mg/kg) and N. sativa (200mg/kg) were administrated orally. Finally, the renal tissue, urine and blood samples were collected and submitted to measure of redox markers, osmolarity and renal index. The renal content of total thiol and superoxide dismutase (SOD) activity significantly decreased and Malondialdehyde (MDA) concentration increased in Adriamycin group compared to control group. The renal content of total thiol and SOD activity significantly enhanced and MDA concentration reduced in treated-mixed extract of C. longa and N. sativa along with ADR group compared to ADR group. The mixed extract did not restore increased renal index percentage induced by ADR. There also was no significant difference in urine and serum osmolarity between the groups. hydro-alcoholic extracts of N.sativa and C.longa led to an improvement in ADR-induced oxidative stress and mixed administration of the extracts enhanced the aforementioned therapeutic effect.

Modulatory effects of tamoxifen (TAM) on the central nervous system have been reported. The effects of TAM on spatial and nonspatial learning and memory impairments induced by scopolamine and the brain tissues oxidative damage was investigated.

The ovariectomized (OVX) rats were divided and treated: (1) Control (saline), (2) scopolamine (Sco; 2 mg/kg, 30 min before behavioral tests), (3–5) Sco-TAM 1, Sco-TAM 3 and Sco-TAM 10. TAM (1, 3 or 10 mg/kg; i.p.) was daily administered for 6 weeks.

In Morris water maze (MWM), both the latency and traveled distance in the Sco-group were higher than control (P < 0.001) while, in the Sco-TAM 10 group it was lower than Sco-group (P < 0.05). In passive avoidance test, the latency to enter the dark compartment was higher than control (P = 0.05 – P < 0.01). Pretreatment by all three doses of TAM prolonged the latency to enter the dark compartment compared to Sco-group (P < 0.05 – P < 0.001). The brain tissues malondialdehyde (MDA) concentration was increased while, superoxide dismutase activity (SOD) decreased in the Sco-group compared to control (P < 0.05 – P < 0.01). Pretreatment by TAM lowered the concentration of MDA while, increased SOD compared to Sco-group (P < 0.05 – P < 0.001).

It is suggested that TAM prevents spatial and nonspatial learning and memory impairments induced by scopolamine in OVX rats. The possible mechanism(s) might at least in part be due to protection against the brain tissues oxidative damage.