t. ghazanfari

The aim of this study was to separate the chemical victims of mustard gas into exposed to and non-exposed groups to sulfur mustard using classical discriminant analysis and two-state logistic regression and selection of the best analysis.

The present study is a historical group that was conducted from 2005 to 2014. By observation method and systematic sampling, 284 people were included in the study including 216 people from Sardasht City as an exposed group and 68 people from Rabat City as a control group who were in all respects compared to the case group. Using classical discriminant analysis and logistic regression methods, 32 quantitative variables were examined and finally these two methods were compared using rock curve analysis. SPSS 21 software was used for analysis.

The 8 significant variables that had the highest ability to differentiate the groups (FEV1/FVC ratio, testosterone, cholesterol, phosphorus, conjugated bilirubin, red blood cell count, hemoglobin and hematocrit) were selected and entered into the main models. Using the rock curve, the cutting points of the variables were determined and the sensitivity and specificity values ​​for discriminant analysis were 78% and 77.5%, respectively, and its sub-curved surface was 81.2%. In differentiating the groups, testosterone index was the strongest variable and conjugated bilirubin factor was the weakest variable. In logistic regression model, FEV1/FVC, testosterone and phosphorus ratio variables were significant (p<0.05). The sensitivity and specificity of this model were 80% and 75%, respectively, the rock curvature level was 81.4% and the value of R^2 was 0.308.

In the separation of chemical victims, the classical discriminant analysis and logistic regression methods have similar results, but discriminant analysis is a more appropriate model due to the presentation of the diagnostic function.

Cutaneous leishmaniasis (CL) is a protozoan disease of the skin caused by a wide range of italic species. The disease is endemic in many countries. It has been recognized as a major public health problem in Iran. Many treatments have been suggested for it but none of them was fully effective.

The objective of this study was to compare the efficacy of a 5% garlic cream with placebo in CL.

A double blind, placebo controlled study was performed in Isfahan and Jahrom in 1997 and 1998. 197 patients were randomly selected. Exclusion criteria were: pregnancy, lactation, age less than 5 years and duration of disease more than 100 days. Each patient received garlic cream 5% or placebo for 3 weeks and was followed for another period of 40 days.

The study was completed as planned in 171 patients. 96 were treated with garlic 5% cream and 75 with placebo. Complete healing occurred in 18 (18.75%) of garlic group in comparison with 15 (20%) of placebo group. The difference was not significant (P=0.9865).

5% garlic cream was not effective in treatment of cutaneous leishmaniasis. Further studies with higher concentrations or different vehicle are needed.