جستجوی مقالات مرتبط با کلیدواژه "عامل نکروز تومور آلفا" در نشریات گروه "تربیت بدنی"

Today, finding the best recovery method for athletes is very important. The purpose of this study wasto measure the effects of repeated sprint activities (RSA) and 12 minutes immersion (CWI) in cold water (14 ₒ C) immediately after performance of RSA on fatigue serum inflammatory biomarkers as Interleukin-6 (IL-6) and Tumor necrosis factor alpha (TNF-α) in active men.

The research adopted a quasi-experimentalmethod and the statistical population was20-26 year-old active men.  in this was 20 active males after performance of RSA randomlywere divided into two groups as control passive recovery (PAS) and experimental (CWI) groups. Blood samples were taken from both groups, immediately before and 24 hours after immersion in cold water. For statistical analysistheWilcoxon and Repeated measures and ANOVA tests were used (p

Some cytokines are introduced as the predictors of cardiovascular disease risk factors. The aim of this study was to investigate the effect of 8 weeks of continuous and interval training on serum TNF-ɑ, IL-6 and hs-CRP levels in female basketball players. Thirty eight healthy female basketball players voluntarily participated in this study, and further they randomly divided into three groups including continuous, interval and control groups. Blood samples were collected in both pre and post-test after 12 hours of fasting. Continuous and interval training were performed 3 times per week for eight weeks. Eight weeks of continuous and interval training significantly reduced serum IL-6, TNF-ɑ and hs-CRP levels (p<0.05); while these variables had no significant effect in the control group (p>0.05). Moreover, significant difference were found for IL-6 levels between continuous and control group (p=0.005). The same result also were found for TNF-ɑ levels between interval and control groups (p=0.001) as well as also between continuous training and control group (p=0.03). The mean changes of hs-CRP showed a significant difference between interval and control group (p=0.0001) and also between interval and continuous training group (p=0.01). In this way, Interval training versus aerobic training led to further decrease in levels of IL-6 (20% vs. 13.19%), TNF-ɑ (42.12% vs 29.31%) and hs CRP (52.17% vs 21.17%), respectively. Both of continuous and interval training during eight weeks could significantly decreased inflammatory cytokines levels, moreover, interval training made the most changes in these cytokines. Therefore, continuous and interval training are recommended to prevent and control cardiovascular disease risk factors.

Aerobic endurance training is the most efficient type of physical training. It indicate beneficial effects on obese subjects because of decreasing chronic inflammation. Apelin plays a key role in energy metabolism adjustment. Therefore it is important to study the levels of blood apelin in obese people. The aim of this study was to investigate the effects of 12 weeks of progressive aerobic training on the level of apelin, TNF-α, IL-6 and CRP in obese inactive women. In this semi-experimental study, 30 obese inactive women (mean age 37.19±1.75 yr, body mass index 35.01±2.42 kg/m2) with no regular physical training were selected. They were randomly divided into two groups (N=15) including training and control groups. The individuals in the training group performed a progressive aerobic training protocol including running 3 days a week during period of 12 weeks up to the 60 to 80 percent of maximum heart rate. The average of exercise duration in every session was approximately 60 minutes. Fasting blood samples were taken before and after protocol. The concentrations of biochemical markers in plasma and serum were measured by commercial ELISA kits. To extraction of results the two-way ANOVA 2×2 test was applied and the significance level was considered as p≤0.05. Two-way ANOVA was demonstrated the significant decreases in levels of apelin (p<0.001), TNF-α (p<0.001), IL-6 (p<0.001) and CRP (p<0.001) after progressive aerobic training. Progressive aerobic training is related to reduction of fat tissue and cytokines production and consequently decreases in apelin levels. The apelin reduction can be considered as a well-known mechanism to decrease inflammation in obese inactive women.

Considering the important role of inflammation in pulmonary disorders the purpose of this study was to investigate the effect of a period of swimming training on Tumor necrosis factor alpha (TNF-α)and Nuclear factor- kappa B (NF-κB) gene expression in lung tissue of wistar rats. Twenty wistar rats of five weeks ages with the weight range of 102±23 g randomly divided into control (n=10) and swimming training groups (n=10). The training protocol included three months of swimming (5 times per week) which begun from 25 minutes in the first week (with the water flow intensity of 4 liters per minute) and reached to 60 minutes (with the water flow intensity of 10 liters per minute) at the final week. Quantitative Real-Time PCR used for detecting and quantifying expression profiles of TNF-αand NF-κB genes in the lung tissue of rats. Kolmogorov-Smirnov test was used to test the normality of data distribution and Independent t test was used to determine the between group differences (α

The aim of the present study was to investigate the effects of 5 weeks of high-intensity interval training (HIIT) on TNF-α level in visceral and subcutaneous adipose tissue in male Wistar rats. Twenty male rats (age: 8 weeks, weight: 190 ± 10 g) were randomly divided into HIIT training and control groups. Training program consisted of high-intensity speed running. Training program was performed for 5 weeks, 5 sessions per week. In the first week, animals completed 6 high-intensity interval bouts in 2 minutes at 37 m/min with 1-min rest intervals. In the second, third, fourth and fifth weeks the number of bouts increased respectively to 7, 9, 10 and 12, and the speed increased respectively to 40, 43, 49, 52 m/min. Seventy-two hours after the last training session, animals was anesthetized with a cocktail of xialyzine and ketamine, and visceral and subcutaneous adipose was removed. ELISA method was used for TNF-α, glucose and insulin measurement. Independent-samples t test was used for data analysis and significance level was set at 0.05. The results indicated that five weeks of HIIT training caused significant decreases in visceral and subcutaneous levels of TNF-α and plasma insulin (P 0.001) as well as insulin resistance (P

The rise in plasma levels of FIB (fibrinogen), TNFα (tumor necrosis factor-alpha), IL- 6 (Interleukin-6), HCY (homocysteine), and CRP (C-reactive protein) are known to be indexes of risk factors for cardiovascular events. The aim of the present study was to investigate the effect of 8 weeks of an aerobic exercise program on indexes of risk factors for cardiovascular events in inactive obese women. 20 inactive obese women with BMI≥30 kg/m2 were volunteered to take part in this study and were randomly divided into two groups of aerobic and control. The exercise program consisted of 8 weeks, three sessions per week, each session 30 min. with 60-65% MHR. Before and after the exercise protocol, blood samples of both groups (in fasting state) were collected by ELISA method to measure the variables under study. The data were analyzed through paired t test and independent t test (P

To date, most studies have focused on continuous aerobic training and there is not comprehensive information about the influence of discontinuous aerobic training on cardiovascular risk biomarkers. Taking this into consideration, the purpose of the present study is to investigate the influence of an 8-week discontinuous aerobic training program (3×10 min) on cardiovascular risk biomarkers in inactive obese women. 20 inactive obese women with BMI≥30Kg/m2 volunteered to take part in this study. They were randomly divided into two equal groups of 10 called the discontinuous aerobic group and control group. The training was programmed for 8 weeks, 3 sessions in each week and three 10-min exercises in each session with a 5-min break between each exercise and 60 to 65 percent of maximum heart rate. The blood sampling ELISA method was used to measure the variables required from the discontinuous and control groups before and after the training program at overnight fast. The data were analyzed using paired t-test and independent t-test in the significance level of (P<0.05). The results revealed that discontinuous training program significantly decrease the level of HCY, FIB, TNFα, IL-6, and CRP in obese women (P<0.05). Also the results of independent t-test indicated that there is a significant difference between discontinuous aerobic training and control groups regarding the considered variables (P<0.05).The current study suggested that the discontinuous aerobic training can lead to the plasma reduction on cardiovascular risk factors in obese women. This reduction can be influential in preventing, controlling, and decreasing cardiovascular biomarkers.