جستجوی مقالات مرتبط با کلیدواژه « پروتئین واکنشی c » در نشریات گروه « تربیت بدنی »

The aim of this study was to evaluate the effect of HMB-FA supplementation on inflammatory parameters during a two-race microcycle in Soccer players.

A total of 24 Soccer players (mean age: 23±30 years) were randomly divided into two groups supplement (n = 12) and placebo (n = 12). Subjects in the supplement group and the placebo group participated in a weekly microcycle with two races per week. Subjects in the supplement-training group consumed three grams of HMB-FA daily during a weekly soccer cycle. Serum levels of inflammatory markers of interleukin-1 beta, interleukin-6 and reactive protein-C in seven stages (before supplementation, before the first race, after the first race, 24 hours after the first race, before the second race, after from the second race, 24 hours after the second race) were evaluated. For data analysis, repeated measures test and paired t-test and SPSS software version 25 were used. Significance level was considered α = 0.05.

The results of the present study showed that training and two Soccer matches increased all inflammatory indices (for all, P≤0.05).

Consumption of HMB-FA supplement reduces inflammatory factors during a two-match Soccer microcycle, which shows the ability of this supplement to control the inflammatory status of Soccer players in inflammatory conditions caused by two matches per week.

Atherosclerosis is a chronic disease whose first stages can begin in childhood. Obesity is one of the major risk factors for atherosclerosis, which is becoming an epidemic. The increase in prevalence of obesity has focused more attention on the relationship between obesity and atherosclerosis, and although the relationship between obesity and atherosclerosis has been widely reported, its potential mechanisms still need to be further elucidated. Salusins are a new class of bioactive peptides that play an important role as endogenous regulators of atherosclerosis process. Obesity is associated with a chronic inflammatory response characterized by abnormal adipokine production and activation of some pro-inflammatory signaling pathways. Past studies have shown that inflammatory process has a cause and effect relationship with obesity and cardiovascular diseases, including atherosclerosis. Also, arterial endothelial disorder is an early disorder in process of atherosclerosis, and presence of this disorder in obese children has been widely reported. The most important potential factor that will lead to obesity, inflammatory conditions and endothelial dysfunction is immobility. On the other hand, physical activity has wide health benefits and is considered as an important factor in primary and secondary prevention of cardiovascular diseases. Therefore, the current research seeks to investigate the role of physical activity in improving endogenous regulators of atherosclerosis in obese and sedentary children.

 Type 2 diabetes is associated with increased systemic inflammation that may be increased cardiovascular diseases for which exercise training is a potential therapy. The effects of high intensity interval training (HIIT) on inflammatory markers in Type 2 diabetes patients, however, require further elucidation. We therefore performed a systematic review and meta-analysis to investigate the effect of HIIT on inflammatory markers in Type 2 diabetes patients.

 PubMed, Scopus, and Web of Science were searched up to May 2022 for HIIT vs. Control or only HIIT studies on inflammatory makers i.e. CRP, IL-6 and TNF-α in Type 2 diabetes patients. The search was performed using the HIIT, inflammation and type 2 diabetes keywords. Standardized mean difference (SMD) effect sizes and 95% confidence intervals were calculated using CMA2 software.

Among the 257 extracted studies, 11 studies including 257 participants (143 women and 114 men) with an age range of 44 to 71 years were included in the meta-analysis. HIIT was beneficial for promoting a reduction in TNF-a [-0.62 (95% CI: -1.85 to -0.13), p = 0.01] and CRP [-0.65 (95% CI: -1.21 to -0.08), p = 0.02]. However, there were no significant evidence for an effect of HIIT on IL-6 [-0.31 (95% CI: -0.70 to -0.06), p = 0.10] in Type 2 diabetes patients.

 These results suggest that HIIT could induce improvements inflammatory cytokines as well as CRP in Type 2 diabetes patients.

Diabetes leads to defects in BDNF function and disturbances in CRP and IL-6 serum levels. The purpose of the study was to determine the effect of eight weeks of simultaneous endurance-resistance exercise on BDNF, CRP, and IL-6 serum levels in type1 diabetic male Wistar rats.

In this experimental study, 30 adults male Wistar rats (250-300 grams and aged six weeks) were randomly divided into three groups including two diabetic groups, diabetic exercise (n=10), diabetic control (n=10) and a non-diabetic group, healthy control (n=10). At the end of the eight-week-old, an amount of 55 mg/kg of body weight of streptozocin (STZ) was injected intraperitoneally, to make diabetic. The diabetic exercise group performed the eight weeks of combined exercises; 5 times per week (endurance exercise with 75% Vo2max on the treadmill and strength training including 15 times climbing the ladder). To measure the serum levels of BDNF, CRP, and IL-6, blood samples were taken. One-way ANOVA and post-hoc Bonferroni test were used to compare between-group and intra-group changes of BDNF, CRP, and IL-6. The significance level was P<0.05.

After eight weeks of endurance-resistance training, BDNF level significantly increased in the diabetic exercise group compared to the diabetic group (P=0.009). Whereas, it significantly decreased in the diabetic control group compared to the healthy control (P=0.0001). CRP levels significantly decreased in the diabetic exercise group compared to the diabetic group (P=0.008). However, it significantly increased the diabetic control group compared to the healthy control (P=0.0001). There was no significant change in IL-6 level (P=0.057).

It is recommended that diabetic people perform eight weeks of simultaneous endurance-resistance exercises to increase BDNF levels and reduce inflammation.

Obesity is one of the most important public health challenges of the present century, which increases the plasma levels of inflammatory cytokines and decreases anti-inflammatory and anti-atherogenic agents. High intensity interval training may be able to stop or reverse these destructive effects. Therefore, the aim of this study was to investigate the effect of 8 weeks of interval training on inflammatory factors in overweight adolescent boys. In a quasi-experimental research project, from overweight adolescent boys (13-18 years old, mean height 154.33 cm, mean body mass index 27.05 kg/m2), 30 subjects were voluntarily assigned to 3 groups (10 subjects each group): short-term interval training (nine 30-second bouts, 100 to 110% of maximum speed with 150 seconds of rest), long-term (four 150-second bouts, 90 to 95% of maximum speed with 240 seconds of rest) and control. 48 hours before the beginning and the end of the training protocol, weight, height, body mass index and fat percentage were measured by a body composition apparatus and blood samples were collected to determine the interleukin-6, interleukin-10 and C-reactive protein indices. The results showed that 8 weeks of high intensity interval training increased interleukin-10 and decreased C-reactive protein. But it had no significant effect on interleukin-6. It was also found that there were no differences between short-term and long-term HIIT in influencing the desired indicators. Based on these findings, it can be said that overweight or obese adolescents may be able to use HIIT to boost their anti-inflammatory system by increasing interleukin-6 and decreasing C-reactive protein. But more studies are needed to determine the effect of this training on interleukin-6.

The aim was to investigate the effect of eight weeks of Pilates training and Celery seeds supplementation on serum CRP and ESR level in middle-aged women with rheumatoid arthritis.

40 women with rheumatoid arthritis referred to Shariati Hospital in Tehran (age: 53.10±5.35 years, weight: 62.37±5.93 kg) were randomly divided into Control (n=10), Training and Placebo (n=10), Supplement (n =10) and Supplement + Training (n =10) groups. The training subjects experienced eight weeks of Pilates exercises, three sessions/week at 65% of MHR up to 60 min. the supplementation groups consumed 1.3 g Celery seeds powder three times daily for eight weeks.

in spite of serum CRP down regulation in Supplement + Training group (p < 0/05), no significant change were recorded for ESR in this group (p≥0/05).

synchronized Pilates training in accompany with Celery seeds supplementation could be beneficial in controlling inflammatory status of patients with rheumatoid arthritis. However, more investigations remain to be done because of the lack of similar evidence and also limitations in this study.

Increased anti-inflammatory cytokines and decreased inflammatory cytokines through exercise is one of the ways to reduce chronic inflammation. Current study aimed at investigating the effect of endurance training on inflammatory markers in male smokers. Two groups: experimental (mean age 25.30 ± 2.95 years, n=10) and control (mean age 26.11 ± 2.76 years, n=10) were selected randomly. Endurance training protocol including of 20 minutes of running with intensity of 55-65% of heart rate reserve was performed by the experimental group during six weeks. 48 hours after the last training session, measurements similar to those before training and blood samples were collected. The data were analyzed by dependent t test within a group and independent t test between the groups (α≤0.05). The results showed that six weeks of endurance training intervention significantly decreased CRP (P=0.012) and significantly increased IL-10 (P=0.01) in the experimental group. The results indicated the effect of exercise on inflammatory markers in male smokers. On the other hand, these findings show that smokers may reduce the side effects of smoking if they have endurance training. But this requires further research on the role of endurance training and its relationship to inflammation.

The purpose of this study was to investigate the changes in plasma C reactive protein (CRP) and Serum amyloid A (SAA) levels following 8 weeks of circuit resistance training in obese men. Twenty six obese men (age; 36.8±7.9 yr, weight; 92.8±10.8 kg, and BMI; 31.5±2.8 kg/m2) voluntarily participated in this study, and were divided into control (n=13) and resistance training (n=13) groups. Subjects in training group performed eight weeks circuit resistance training with 50-85% 1RM (3 days/week). Anthropometrics parameters, as well as plasma levels of CRP and SAA were measured at the baseline and at the end of study. Eight weeks of resistance training induced significant reduction in body weight, BMI and body fat percentage (P≤0.05). Significant reduction in plasma CRP concentration was found in compare with control group (P≤0.05). Plasma SAA levels increased in both control and training groups when compared with baseline levels (P≤0.05), But there was no significant difference in SAA levels changes between two groups. The results of this study showed that circuit resistance training decreases plasma CRP levels, associated with improved in body composition in obese men.

To date, most studies have focused on continuous aerobic training and there is not comprehensive information about the influence of discontinuous aerobic training on cardiovascular risk biomarkers. Taking this into consideration, the purpose of the present study is to investigate the influence of an 8-week discontinuous aerobic training program (3×10 min) on cardiovascular risk biomarkers in inactive obese women. 20 inactive obese women with BMI≥30Kg/m2 volunteered to take part in this study. They were randomly divided into two equal groups of 10 called the discontinuous aerobic group and control group. The training was programmed for 8 weeks, 3 sessions in each week and three 10-min exercises in each session with a 5-min break between each exercise and 60 to 65 percent of maximum heart rate. The blood sampling ELISA method was used to measure the variables required from the discontinuous and control groups before and after the training program at overnight fast. The data were analyzed using paired t-test and independent t-test in the significance level of (P<0.05). The results revealed that discontinuous training program significantly decrease the level of HCY, FIB, TNFα, IL-6, and CRP in obese women (P<0.05). Also the results of independent t-test indicated that there is a significant difference between discontinuous aerobic training and control groups regarding the considered variables (P<0.05).The current study suggested that the discontinuous aerobic training can lead to the plasma reduction on cardiovascular risk factors in obese women. This reduction can be influential in preventing, controlling, and decreasing cardiovascular biomarkers.