جستجوی مقالات مرتبط با کلیدواژه "دیابتی نوع 1" در نشریات گروه "پزشکی"

Type 2 diabetes is a significant health problem. Patients with diabetes disease struggle to control their stress and manage their emotions. Accordingly, emotion regulation seems to be a primary principle for evaluating and managing emotions. In recent years, some researchers have introduced mindfulness-based approaches based on existing cognitive-behavioral interventions (the third wave of behavioral therapy). The present study aimed to determine the effects of mindfulness therapy on the difficulty in regulating emotions and cognitive fusion in patients with type 2 diabetes.

This research was a quasi-experimental study with a pretest-posttest design and a control group. The study’s statistical population consisted of all female patients with type 2 diabetes, referring to the diabetes center of Karaj City, Iran, in the Spring of 2018. To collect data, a sample of 30 women was selected using a convenience sampling method. The inclusion criteria were as follows: being 20 to 50 years old, having a three-month sugar level of more than 0.7, not suffering from any other disease, not changing the dose of insulin consumed during the three months of the experiment, not undergoing any other treatment, not taking psychiatric drugs and being interested in participating in the research. The exclusion criteria for the experimental group were as follows: excessive absenteeism in training sessions and lack of cooperation in the training program. The research tools were the Difficulties in Emotion Regulation Scale (Graz and Roemer, 2004) and the Cognitive Fusion Questionnaire (Gillanders et al., 2014). The experimental group subjects received 8 sessions of mindfulness therapy, and the control group received no treatment. The obtained data were analyzed by SPSS using univariate and multivariate analysis of covariance analysis. The significance level was set at 0.01.

The present study results demonstrated a significant difference between the experimental and control groups in difficulty in emotion regulation (p<0.001) and cognitive fusion (p<0.001). The mean±SD values of difficulty in emotion regulation of the experimental group before and after the intervention were 20.40±2.44 and 18.36±2.38, respectively; the same scores for the cognitive diffusion were 41.80±2.50 and 40.86±2.23 respectively. Additionally, the effect size values were 0.476 for the difficulty score in emotion regulation and 0.361 for cognitive fusion.

Based on the findings, mindfulness therapy effectively reduces the difficulty in emotion regulation and cognitive fusion of type 2 diabetic patients. Therefore, in addition to pharmacotherapies, it is recommended to consider psychological aspects to reduce the mental problems of patients with type 2 diabetes.

The prevalence of diabetes has made necessary changes in lifestyle to prevent its complications. In this study, the effect of moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) with staxanthin supplementation on inflammatory biomarkers in the cardiac tissue of diabetic rats was investigated.

In this study, 42 male rats (age six weeks), after induction of type 2 diabetes,were randomly divided into seven groups (six in each group): 1)diabetic control; 2) diabetic Sham; 3) diabetes+supplement; 4) diabetes+HIIT; 5) diabetes+HIIT+supplement; 6) diabetes+MICT; and 7) diabetes+MICT+supplement. The HIIT groups ran with an intensity of 80% VO2max, and MICT groups ran with an intensity of about 65% to 75% VO2max on the treadmill (five sessions per week for eight weeks). The supplement was taken daily at a dose of 3 mg per kg. The cardiac tissue was removed 24h after the last training session (night fasting). Inflammatory biomarkers (IL-1b, IL-6, TNF-α, and CRP) of the cardiac tissue were measured by Western blotting.

After eight weeks of training, inflammatory biomarkers showed a significant decrease compared to the control group (p<0.05), and no significant changes were observed in the supplement group.

Due to the effect of MICT and HIIT in reducing inflammatory biomarkers, it can be used as a therapeutic strategy. It seems that the MICT with supplements may have more effective in these patients, while supplements alone have no effect on inflammatory markers.

An increase in malondialdehyde and a decrease in the total antioxidant capacity associated with high blood glucose and insulin resistance in type 2 diabetes cause damage to the testicular tissue and structure. The aim of this study was to evaluate the effect of different aerobic training intensities on serum levels of malondialdehyde, total antioxidant capacity and testicular structure in male diabetic rats.
  In this study, 46 Wistar rats with an average weight of 205‏±‏45 grams were randomly assigned into four groups: healthy control, control of diabetic, diabetic with moderate-intensity interval training (MICT) and diabetic with high-intensity interval training (HIIT). The training groups trained the exercise program for 10 weeks by treadmill and their blood serum and testis tissue were collected after the last training session. Data were analyzed using one-way ANOVA and Tukey post-hoc test at a significance level of 0.05%.
  MICT and HIIT training caused a significantly decreased fasting blood glucose and MDA and significantly increased TAC in diabetic training groups compared to diabetic control group (p<0.05). Also, 10 weeks of MICT and HIIT training improved the testicular structure, especially the testis volume, seminiferous tubules volume, interstitial tissue volume and left testicle weight in diabetic training groups compared to the control group (p<0.05). There was also no significant difference between the changes for the two methods of MICT and HIIT exercises regarding dependent variables.
  It seems that two methods of MICT and HIIT training by reducing blood glucose, insulin resistance index and serum level of MDA and enhancement of TAC have positive effects on the improvement of testicular structure in diabetic rats. With these two methods of training, there were no different effects on mentioned variables.

Bachground: Type 2 diabetes is an important public health problem that involves many people. Exercise and physical activity play an important role in preventing and controlling it. Therefore, this study aimed to compare the effects of two different frequencies of aerobic exercise with the same volume and detraining period on the levels of irisin hormone, lipid profiles, and insulin resistance index in obese women with type 2 diabetes.
In this quasi-experimental study, 36 obese women with type 2 diabetes were randomly allocated into three groups (n = 12 per group). Group 1 and group 2 performed 8 weeks of intensity aerobic exercise (Group 1=3 times and Group 2=6 times a week, with the same volume) with 60-75 percent of maximum heart rate. Samples were taken before intervention, 48 hours after the first training session, and two weeks after the last training session.
After 8 weeks of intervention, the intergroup results showed that weight, body fat, and body mass index were significantly reduced only in group 1, whereas in both groups, the insulin resistance index reduced and irisin levels increased significantly (P Given the results of this study, the longer duration exercise protocol was of a more significant impact on the control of factors involved in type 2 diabetes than the exercise protocol with more frequent, short-term training sessions. Therefore, it can be concluded that the duration of an exercise program is an effective factor in the prevention and control of type 2 diabetes, which should be considered in the design and planning of exercise.