جستجوی مقالات مرتبط با کلیدواژه "رینگر لاکتات" در نشریات گروه "پزشکی"

Clear changes in neonatal acid-base in the early minutes can have adverse effects on the hemodynamic status of the neonate; different serums have different effects on the acid-base status. Therefore, this study was performed with aim to compare the effects of 0.9% sodium chloride serum with Ringer lactate serum on maternal and neonatal acid-base status in elective cesarean section.

This triple-blind randomized clinical trial study was performed with participation of 48 pregnant women in 2018-2019. The first group received 0.9 sodium chloride serum and the second group received ringer lactate serum. Arterial blood samples before cesarean section (mother) and after cesarean section (mother and baby) and neonatal Apgar score in the first and fifth minutes were recorded and compared between the two groups. Data were analyzed by SPSS software (version 21) and independent t-test, paired t-test, Chi-square test, Mann-Whitney test, analysis of variance and repeated measures. P<0.05 was considered statistically significant.

All factors studied in ABG were significant between the two groups of mothers, indicating a higher acidity in the 0.9% sodium chloride group than the ringer-lactate group (p<0.05). On the other hand, there was no significant difference between the studied factors in neonates (ABG and Apgar scores) between the two groups (p>0.05).

0.9% sodium chloride compared to lactated ringer causes acidosis in mothers undergoing elective cesarean section with spinal anesthesia, but none of them has a significant effect on the acid-base status of the infant. Ringer's lactate serum seems to be a good alternative to 0.9% sodium chloride serum, especially in mothers who are at higher risk for acidosis.

OSCE is a combination of simulation tasks to assess medical students'' skills in diagnosis and treatment of diseases. it is vital to measure the quality of an OSCE. One of the important steps in assessing the quality of a test is to determine it''s reliability. This study aimed to determine the reliability coefficient of the second clinical skills test in Mashhad by using generalizability theory.
Subjects & The OSCE was conducted in two days and consists of 15 parallel stations. 75 students and 30 examiners participated in this test. Check lists collected and recorded in Excel. Variances and mean squares (MS) calculated by using SPSS. Variance for stations¡ students and examiners and generalizability and reliability coefficients calculated by using EDUG. Mann-Whitney U and Chi square tests were used for assessing relation between students’ gender and score¡ raters’ gender and score and relation between students gender and raters gender.
There was no significant relationship between gender of students and their scores¡ gender of examiners and students’ scores¡ and between gender of students and gender of examiners. Reliability coefficient was calculated 0/98 and interaction between students¡ examiners and station component had the largest effect on creating measurement error.
this exam had a good reliability coefficient and according to results we can say¡ using Generalizability Theory for estimating the reliability coefficient¡ measurement error¡ and to identify impact of any facets on measurement error is a logical way. However¡ more research needs to be done.

It is important to keep a sufficient amount of circulating blood and tissue perfusion during surgery. Different compounds including crystalloid and colloidal solutions are proposed for this purpose. There is a lot of evidence that there is a clinically difference in the use of various crystalloids. In this study, the effect of two methods of fluid therapy with Ringer’s Lactate and Ringer’s solution on acid-base balance and postoperative complications in patients candidate for elective operation was studied.
Subjects & This clinical trial study was performed on 86 patients undergoing major anesthetic surgery in ASA class I and II and had no heart and kidney problems. The fluid therapy was performed with a ringer's lactate solution in one group (n = 43) and in the other group with ringer solution (n = 43). Before starting surgery, blood samples were taken for hemoglobin, hematocrit, albumin and electrolytes, and arterial blood samples for analysis of arterial blood gas. At the end of the anesthesia, the patient was transferred to the recovery and was evaluated for recovery in the wake delay and other complications such as nausea and vomiting.
In this study, hemoglobin and hematocrit were significantly reduced in ringer's lactate groups after fluid therapy, and the amount of albumin after fluid therapy was reduced in the ringer's lactate group.There was no significant difference in sodium levels in both groups before and after fluid therapy. However, the amount of potassium and calcium significantly increased after the liquid therapy in the ringer's lactate group and the amount of chlorine in the ringer group significantly increased. Bicarbonate and PH were increased after fluid therapy in ringer's lactate group and decreased significantly in ringer group. Also, the amount of bleeding during operation and duration of postoperative hospitalization was higher in ringer group, but this difference was not statistically significant. Nausea and vomiting were reported more in the ringer group than in the ringer's lactate group, but this difference was not statistically significant. Also, the delay in waking in the ringer group was significantly higher than ringer's lactate group.
According to the findings of this study, it seems that in elective surgery, the replacement of crystalloids ringer and ringer's lactate, there is a significant difference in PH and postoperative complications following the use of these serums. The blood acidity following fluid therapy with ringer was higher in comparison to fluid therapy with ringer's lactate, and the delay in awakening in this group was reported high.

the most common cause of shock in surgical or trauma patients is blood loss due to bleeding. The usual treatment for this type of shock is the replacement of isotonic fluids. The aim of this project is to compare the effect of hypertonic saline (3.5%) and ringer lactate in the resuscitation of trauma patients with hypovolemic shock.
Subjects and In this double blind clinical trial study, using a simple random sampling, trauma patients referred to Ahwaz Golestan hospital emergency room, were divided into the case and control groups(85 cases VS.85 control). The group received a hypertonic saline solution 3.5% and intervention was done in the control group using the routine method of resuscitation, including administration of of ringer lactate.
In this study. 170 patients (157 males and 13 females) were studied. The required time and the volume of the fluid intake to reach Blood pressure of 90 mmHg in the hypertonic-treated case group was significantly lower than the ringer lactate-treated control group. In a comparison between other variables, except serum sodium, 24 hr after the start of treatment, no significant difference was seen between the two groups.
At the start of the treatment for patients with patients with hypovolemic shock following trauma, the use of hypertonic saline with a limited volume caused the reduced amount of fluid intake and the decreased the time of getting out of shock. Therefore, the use of hypertonic saline in patients with hypovolemic shock is recommended.

Spinal anesthesia is often recommended as a safe and preferred substitute for general anesthesia. The hemodynamic benefits of spinal anesthesia over general anesthesia include a minimum decrease in myocardial contractility and only modest decreases in blood pressure and cardiac output. However، spinal anesthesia is associated with some complications (such as unstable hemodynamic status) during surgery that may lead to mortality in patients under operation. Hydroxyethyl starch (Voluven) is a substance used to preserve a patient’s hemodynamic stability during surgery. This study compared the use of lactated Ringer’s solution and Voluven as preload in patients under spinal anesthesia. This clinical trial study was performed in Kashani Hospital (Isfahan، Iran) during 2012. We selected 80 patients who were scheduled for lower extremity orthopedic procedures under spinal anesthesia. The subjects were randomly allocated to two groups and preloaded with either lactated Ringer’s solution or Voluven for 20 minutes. Hemodynamic indexes including blood pressure، heart rate، and oxygen saturation were monitored before the surgery and at the first، third، fifth، tenth، fifteenth، and thirtieth minutes after the operation. The collected data was analyzed with SPSS. The mean systolic blood pressure in the lactated Ringer’s solution group was 129. 3 ± 16. 7 mmHg at baseline and 113. 2 ± 16. 2 mmHg at the end of the operation. The corresponding values in the Voluven group were 128. 1 ± 14. 3 and 113. 8 ± 16. 1 mmHg. No statistically significant differences were observed between the two groups in terms of systolic or diastolic blood pressure، heart rate، and oxygen saturation. Although using Voluven in spinal anesthesia is supposed to result in better hemodynamic stability، we failed to find a significant difference between Voluven and lactated Ringer’s solution. Therefore، either of them can be used for preloading based on their cost and availability.

Metabolic acidosis can be harmful and can complicate cardiopulmonary bypass (CPB) during coronary artery bypass graft surgery. We hypothesized that the pump prime can cause this disturbance. We compared effects of Ringer solution with Ringer Lactate, two types of priming fluid in producing metabolic acidosis in patients undergoing coronary artery bypass graft (CABG). .. In a prospective, double-blind, randomized clinical trial 50 patients undergoing CABG were evaluated at Seiedalshohada hospital of Urmia-Iran. Sampling of arterial blood was performed at three time intervals: Before CPB (t1), 5 minutes after initiation of CPB(t2), and at rewarming period (t3). Measurement of pH, HCO3, PaCO2, Lactate and Cl at each collection point were performed and the results were analyzed. The decrease in pH was seen in both groups and was significant between two groups in the second interval (Ringer: 7.38±0.05 vs. Ringer Lactate: 7.41±0.05, p=0.02). Also in this interval, Lactate had significant difference (Ringer: 2.44±0.9 mmol/L vs. Ringer Lactate: 3.2±0.4 mmol/L, p=0.02) and serum level of chloride was higher in Ringer group (Ringer: 116.6±3.08 mEq/L vs. Ringer Lactate: 113.4±3.9 mEq/L, p: 0.0002) Our findings showed that Ringer Lactate solution in comparison with Ringer had fewer effects on acid-base changes during cardiopulmonary bypass in patients under coronary artery bypass graft.

Spinal anesthesia induced hypotension is common and it could be serious and life threatening. Occasionally many types of solutions use for prevention. We compared ringer lacatated (RL) vs Hetastarch (HS) about cardiac output reductions. Methods and materials: This is a randomized clinical trial which has done on 60 lower extremity orthopedic patients who went under surgery whereas spinal anesthesia has done for them. We used from electrovelosimetery for our evaluations. Base line heart rate، systolic and diastolic blood pressure and cardiac output were similar in both groups. whereas they were apparently reduced in ringer lactated group. This study showed effectiveness of hetastarch 6% in preventing of hemodynamic parameters changes in patients undergoing spinal anesthesia in comparison with ringer lactated solutions.