جستجوی مقالات مرتبط با کلیدواژه "عوارض نورولوژیک" در نشریات گروه "پزشکی"

Phenylketonuria is a type of congenital and genetic metabolic disease of autosomal recessive type, which due to the deficiency or lack of phenylalanine hydroxylase enzyme, the amino acid phenylalanine is not converted to tyrosine and causes an increase of phenylalanine in the blood, especially in the brain, and as a result, causes irreversible complications including irreversible mental retardation. The aim of this study was to investigate the IQ of children with phenylketonuria identified in the national PKU screening program for children over 5 years of age.

This cross-sectional study was conducted in the pediatric center of Shahid Motahari hospital in Urmia during 2011-2014. The participants in this study were selected from children with phenylketonuria who referred to the pediatric clinic of Shahid Motahari Hospital in Urmia and were included in the study. Twenty-five children were included in the study using the full number method, and the required information was extracted from the patients' files and analyzed.

The mean age of the studied children was 6.32±4.33 years and the average age of diagnosis was 30.28±52.24 days. The mean level of phenylalanine mg/dl was 5.40±4.33 and the mean IQ was 93.56±12.99. The results showed that 18 children (72%) have medium to high IQ. Adherence to the diet was observed in the majority of 21 patients (84%). The results of the analysis showed that IQ has a statistically significant relationship with dietary compliance and phenylalanine level (P<0.05).

The PKU screening program in West Azerbaijan province has been effective and we have seen a reduction in the complications of this disease. However, despite the follow-up and implementation of the program, we still see some special complications such as mental retardation, which requires the coherence and continuity of the program in order to minimize the complications caused by this disease.

This paper reviews various types of inducing hypothermia and related nursing care after cardiopulmonary arrest. The patient experiencing post-resuscitation syndrome after cardiopulmonary arrest, requires admission in critical care unit to receive intensive care and constant monitoring. Electronic databases was searched out to find related articles published within the last 5 year about hypothermia therapy and cardiopulmonary arrest. Some textbooks was also read to prepare this paper. Cooling techniques can be divided to noninvasive and invasive methods. Ice packs application to the groin, torso, axillae, and neck is an example of noninvasive cooling technique. Invasive cooling techniques include cold infusion, Intravascular cooling, and venovenous technique. Conclusion. Hypothermia therapy can be recommended as an effective method to reduce complications following cardiopulmonary arrest.

Neurologic complications following cardiac surgery result in increased morbidity and mortality. Although the incidence of overt squeal has traditionally been higher in patients undergoing isolated intracardiac procedures, recent studies show that the incidence of stroke for coronary artery bypass grafting (CABG), in the range of 1 to 4%. Postoperative cognitive deficits also are a source of morbidity and occur frequently even in low-risk patients undergoing cardiac surgery. Certain predictors have been validated in multiple studies but have not been validated in multiple populations. In a retrospective descriptive cross-sectional study we evaluate d documents of patients who had neurologic complication after open heart surgery. Demographic data, the history of previous hypertension, diabetes mellitus, stroke, perioperative conditions such as pump time, serum cratinine, blood sugar, and hematocrit were recorded. All the data were collected in patients with neurologic complications that were confirmed by consult. Approximately 514 patients had open heart operation during May 2005-2007. Twenty one patients (4.08%) had neurologic problems during intensive care unit staying. Cerebrovascular accident occurred in 9 (1.7%) and cognitive disorders in 12 (2.33%) of patients. Five (23.8%) patients had history of diabetes mellitus, and nine (42.8%) patients had history of hypertension. Neurologic complications can occur in low risk patients after cardiac anesthesia. Some predictors were postulated but the reliability of these criteria is not clear. Further research about techniques of preventing or mitigating cerebral injury or predictors particularly in high-risk patients is needed.