جستجوی مقالات مرتبط با کلیدواژه "کافور" در نشریات گروه "پزشکی"

In recent years، many authors considered the effects of honey in treatment of different types of wounds. Pressure ulcers are one of the most important health problems with a challenging treatment. In current study، we evaluated the effects of an ointment containing honey، sesame and camphor in treating pressure ulcers in diabetic patients. In current randomized clinical trial، 60 patients assigned to two groups randomly. Daily irrigation using normal saline and dressing with sterile gauze was performed. In control group، placebo and in case group، the ointment containing honey، sesame and camphor (Kimia ointment) was used twice a day for 8 weeks locally. Before and after the treatment، PUSH tool 3. 0 was completed. Also، the rate of infection requiring surgical debridement was compared between groups. Mann-Withney U، Wilcoxon and chi-square tests were used. Two groups were the same in terms of sex and age. There were one and 5 patients required surgical debridement in case and control groups، respectively (p=0. 195). The PUSH score decreased significantly in two groups after the treatment (p<0. 001). Before the treatment، the PUSH scores were the same. At the last visit، the PUSH score in ointment and placebo group was 4. 9±1 and 6. 8±1. 2، respectively (p<0. 001). Treating pressure ulcers in diabetic patients applying ointment-containing honey، sesame and camphor can be helpful in accelerating the healing process. However، more extensive studies are needed.

Camphor stimulates the nervous system and the circulatory system، reduces lactation، and prevents conception and embryo embedding. We investigated the effects of camphor on the pituitary-gonadal hormonal axis and concentration of steroidal hormones. The parameters investigated were concentrations of LH، FSH، estrogen، progesterone، and testosterone. Forty adult female rats at a mean weight of 180 ± 20 grams were divided into five groups. Camphor solution was prepared in olive oil at 25، 50، and 100 mg/kg doses، and 0. 2 cc injections were done intraperitoneally every day for 2 weeks. The control group received no injection. The sham group received olive oil (as solvent of camphor) and treatment groups of 1، 2، and 3 received doses of 25، 50، and 100 mg/kg. The treatment groups were sacrificed one day after the last injection، and their hearts were dissected and blood samples were obtained. The concentrations of the hormones were measured by the ELISA test، and the results were evaluated via the t-test، ANOVA، and Duncan. The results showed a significant decrease in the concentrations of testosterone and progesterone (p value < 0. 05) and a significant increase in the concentrations of LH and FSH (p value <0. 05). Camphor augmented oogenesis via effecting a rise in the concentrations of LH and FSH in our rats.

Background and In Iranian traditional medicine it has been widely believed that camphor is a suppressor of sexual desire. Based on this idea and the few studies about this issue we examined the effect of camphor on the histological changes and spermatogenesis phenomena in the mouse reproductive system. In this experimental study 24 premature male balb/c mice were selected and divided into four (2 experimental and 2 control) groups. Experimental groups 1 and 2 were administered daily 30 mg/kg body weight dissolved camphor in olive oil (orally) for 10 and 20 days respectively. The control groups received the same volume of olive oil during the same periods. At the end of the exposure time each group was anesthetized and their testes were routinely removed for obtaining serial sections and histological staining. The obtained data were analyzed using t-test. The study data indicated that although the mean external diameter of the somniferous tubules did not show significant differences in experimental and control groups the mean internal diameter tubules (26/31±1/56) of the experimental groups (versus control groups 42/38±2/19) decreased by %25 and mature sexual cells (17/±3/71) in the experimental groups (versus control groups 28±3/92) decreased by %12. The results of the present study indicated that administration of camphor significantly decreased the internal diameter of Somniferous tubules and reduced maturity of sexual cells; hence affecting the reproductive system of the male mice with structural changes.