جستجوی مقالات مرتبط با کلیدواژه « achillea wilhelmsii » در نشریات گروه « پزشکی »

Monitoring of traffic emissions is a good way to build a safe ecosystem for living organisms. Therefore, the present study was conducted to assess the feasibility of using Achillea wilhelmsii and Cardaria draba located along the suburban roads of Hamadan for Zn, Pb and Ni removal by their aerial and underground organs in 2020.

In this descriptive study, after selecting 3 sampling stations, a total of 126 plant samples and 63 soil samples were collected. In the laboratory, the samples were prepared, and were then digested with acid. Subsequentely, the concentration of each heavy metal was measured by inductively coupled plasma-optical emission spectroscopy (ICP-OES). Moreover, bioconcentration factor (BCF), bioaccumulation factor (BAF), transfer factor (TF) and metal accumulation index (MAI) were also calculated. Statistical analyses of the results were performed using SPSS statistical software.

The mean values of BCF and BAF in both A. wilhelmsii and C. draba for all tested elements were greater than 1. On the other hand, A. wilhelmsii showed TF greater than 1 for zinc while C. draba showed TF greater than 1 for zinc and lead. The highest mean values of MAI in unwashed and washed shoots and roots of A. wilhelmsii were 98.48, 64.87 and 72.38, respectively.

Based on the calculated average values of BCF, BAF and TF of each elements, it can be argued that A. wilhelmsii and C. draba species have the potential of phytoextraction and Phytostabilization of the measured heavy metals and can be used for biomonitoring and bioremediation from soil and air in the heavy metals polluted areas.

Achillea wilhelmsii has antioxidant properties and it has been recommended in traditional medicine for depression. The objective of this study was to investigate the chemical compounds of essential oils of aerial part of A. wilhelmsii with and its antidepressant effects in male mice using forced swim and tail suspension tests.

In this study, 60 mice were examined in 6 groups (n = 10), including normal saline as control group, reserpine (5 mg/kg, i.p.) as negative control group, reserpine (5 mg/kg, i.p.) and amitriptyline 18 hours thereafter (2 mg/kg) as positive control group, reserpine (5 mg/kg, i.p.) and essential oil (50, 75 or 100 mg/kg, i.p.) 18 hours thereafter as the intervention group. Forced swim and tail suspension tests were used to measure depression in mice. Antioxidant capacity and chemical composition of the essential oil, as well as antioxidant and malondialdehyde (MDA) content in serum and brain of mice were determined.

Reserpine injection significantly increased the time of immobility in the forced swim and tail suspension tests. Essential oil (50, 75 and 100 mg/kg) and amitriptyline reduced the immobility time. Reserpine and amitriptyline significantly increased serum and brain malondialdehyde (MDA) level, and decreased antioxidant capacity of serum and brain. Essential oil increased antioxidant capacity of serum and brain and reduced malondialdehyde level. Antioxidant power of essential oil was determined 2.32 mg/ml. The major compounds of essential oil were chrysanthenone (14.31%), camphor (13.95%), 1-8 cineole (10.01%), and trans-pinocarveol (9.50%).

Due to the antioxidant power of A. wilhelmsii essential oil in reducing serum and brain malondialdehyde, it seems that the this plant decreased depression symptoms in mice by reducing oxidative stress that it is probably due to terpene bioactive compounds in the essential oil.

The essential oil of Achillea wilhelmsii hasý anti-inflammatory and antioxidant properties. Cisplatin is one of the most important anticancer drugs that are widely used to treat various types of cancers. This study aimed at examining the effects of the essential oil of A. wilhelmsii flowers on cisplatin-induced hepatotoxicity in rats.
In this study, 36 male Wistar rats weighing 200-250 g were divided into 6 groups: 1) control, 2) cisplatin (0.4 mg/kg), 3) cisplatin and essential oil (30 mg/kg), 4) cisplatin and essential oil (60 mg/kg), 5) essential oil (30 mg/kg) and 6) essential oil (60 mg/kg).The injection was performed in the groups every day for 8 weeks. Then, serum levels of liver enzymes were measured and the liver tissue was removed for histopathological studies.
The results showed no significant changes in the albumin level (P>0.05). However, the activities of hepatic factors ALT, AST, ALP and bilirubin were decreased significantly in the groups received essential oil 30 and 60 mg/kg cisplatin and in groups only received the essential oil 30 and 60 mg/kg compared to the cisplatin group (P The essential oil of A. wilhelmsii decreases serum levels of liver factors and bilirubin against cisplatin.

Transaction or laceration and compression of peripheral nerves in accidents and different circumstances resulting Wallerian degeneration which go back to perikaryon through retrograde reaction. This study was done to determine the effect of alchohlic extract of Achillea wilhelmsii on density of motor neurons of spinal cord after sciatic nerve compression in male Wistar rats.
In this experimental study, 30 male wistar rats were randomly allocated into 5 groups: group A: control, group B: compression, group C: compression and treatment with 50 mg/kg/bw of ethanolic extract, group D: compression and treatment with 75 mg/kg/bw of ethanolic extract and group E: compression and treatment with 100 mg/kg/bw of ethanolic extract of Achillea wilhelmsii. After anesthetizing rats, skin and sub cutaneous muscles of right thigh were cut to sciatic nerve appears. Then, compression of sciatic nerve was done by a surgical forceps for 60 seconds, followed by suturing muscle and skin. Extract injection was done intraperitoneally for three weeks after compression. Group A and B were received normal saline. 28 days after compression, samples were prepared from lumbar spinal cord under perfusion method and histological sections were provided serially. After staining, density of motor neurons was calculated by dissector method.
Neuronal density in the compression group (707±38.56) significantly reduced in compare to control group (1740±49.81), (P Ethanolic extract of Achillea wilhelmsii increased neuronal density of rat's spinal cord after compression of sciatic nerve.

Peripheral nerve injuries affect both sensory and motor function, resulting in retrograde reaction to neuronal cell bodies in the ventral horn of spinal cord ventral and their destruction. Achillea wilhelmsii is one of the popular medicinal herbs which grow in dry and semitropical areas worldwide. There are several reports indicating the anti-inflammatory, antispasmodic, antibacterial, and antioxidant effects of Achillea. The purpose of this study was to investigate the protective effects of aqueous extract of Achillea wilhelmsii, on alpha neuronal density after sciatic nerve compression in rats. This experimental study was carried out on 30 male Wistar rats which were divided randomly into 5 groups; group A (control), group B (compression), group C (compression, and treatment with 25 mg/kg aqueous extract), group D (compression and treatment with 50 mg/kg aqueous extract), and group E (compression and treatment with 75 mg/kg aqueous extract). Rats were anesthetized, the thigh muscle of right legs removed, and the sciatic nerve was compressed using a surgical forceps for 60 seconds, and then, thigh muscle and skin were sutured. Intraperitoneal injection of the various doses was performed once every week for 3 weeks. The samples were dissected from lumbar spinal cord by perfusion method and histological slides were prepared serially 28 days after compression. Slides were stained by toluidine blue and erythrosine. Neuronal density of alpha motor neurons of the spinal cord anterior horn was calculated by dissector method. Statistical analysis was performed by Student's t-test and one way ANOVA using SPSS software. The results showed that neuronal density in the compression group decreased significantly compared to the control group (943 ± 59 vs. 1620 ± 51.1, P < 0.001). Neuronal density in group C (1032 ± 40.8), group D (1207 ± 131.3), and group E (1527 ± 46.4) increased significantly in comparison to compression group. The highest neuroprotection was observed in the group which received 75 mg/kg dose of aqueous extract. In conclusion, our results indicate that aqueous extract of Achillea wilhelmsii could protect the sciatic nerve against pathological alterations such as compression.

Nanotechnology is a principally attractive area of research related with production of nanoparticles of variable sizes، shapes، chemical compositions، dispersity and their possible application for human being benefits. Creation، manipulation and utilization of metallic nanoparticles، because of reduction of materials dimensions، affect the physical properties and results in displaying extraordinary thermal، optical and electronic properties of nonmaterial. The biological approaches to synthesis of nanoparticles are better than chemical and physical procedures because of low energy and time expenditure. This method requires no toxic solvents and no dangerous material for environment. Green synthesis of nanoparticles is an eco-friendly method and uses natural solvent.

In this study، the extract of Achillea wilhelmsii as the reducing agent، is used for the biosynthesis of silver nanoparticles. By adding silver nitrate in concentration of 20 mM to extract، the reaction did at room temperature and the color changed from pale yellow to dark showed the silver nanoparticles were generated.

The formation of silver nanoparticles was confirmed by the presence of an absorption peak at 450 nm using spectrophotometer. The size and shape of silver nanoparticles were monitored using scanning electron microscopy that shape of particles was spherical and average size of them was about 110 nm. Precise size and change range of nanoparticles measured by Particle Size Analysis (PSA) between 39-226 nm.

In this study، silver nanoparticles were produced with an eco-friendly biologic approach and without using any harmful chemical.

Achillea is a plant widely used in traditional medicine for gastrointestinal disorders. The aim of this study was to investigate the preventive effect of Achillea wilhelmsii hydro-alcoholic extract on indomethacine-induced gastric ulcer in rats. It was an interventional study and done on six groups of male Wistar rats (n=8 in each group). Three doses of Achillea wilhelmsii extract (200, 400 and 800 mg/kg) were given orally to three groups for three days. After the third day the indomethacine in methyl cellulose (1%) suspension were given orally to the rats and the animals were anesthetized after 6 hours and the pylorus ligatated for one hour. Then the gastric juice extracted and gastric acid titrated by NaOH. The preventive ratio, gastric mucus secretion, NP-SH compounds and lipid peroxidation were measured. Achillea wilhelmsii extract clearly prevented indomethacine- induced ulcer. The Achillea wilhelmsii extract reduced gastric acid secretion by 400 and 800 mg/kg doses compare to the indomethacine group. The extract increased gastric mucus which was significant by 800 mg/kg dose. NP-SH compounds increased significantly by 200 and 800 mg/kg doses in comparison the indomethacine group. Lipid peroxidation noticeably reduced by all three doses. The Achillea wilhelmsii extract showed obviously preventive effect on indomethacine-induced gastric ulcer. Although the potency of the extract on inhibition of gastric acid secretion and increase of gastric mucus secretion are important in this preventive effect but antioxidant effect of the extract is more prominent.

The essential oils of leaves and flowers Achillea wilhelmsii (compositae) collected from the suburb of Neka, north of Iran, in June 2001, were isolated by hydrodistillation and analyzed by means of GC and GC/MS. Fifteen and nineteen components were identified in the oils of the leaves and flowers of Achillea wilhelmsii, respectively. The major constituents of the essential oil of the leaves of A. wilhelmsii were camphor (24.1%), 1,8-cineole (22.3), borneol (11.1) and myrtenol (8.5%). The major constituents of the essential oil of the flowers of A. wilhelmsii were camphor (21.2%), myrtenol (14.4%), myrtenyl acetate (8.9%), yomogi alcohol (8.7%) and borneol (8.2%).