جستجوی مقالات مرتبط با کلیدواژه "bacteriology" در نشریات گروه "پزشکی"

The structure of bacteria consists of various macromolecules such as proteins, polysaccharides, phospholipids and nucleic acids, which, in addition to their role in forming their structure, play an essential role in maintaining their viability and pathogenicity. This study aimed to investigate the application of proteomics in the analysis of proteomic profiles of bacteria and their derived postbiotics.

In this review study, relevant data were collected by searching for the keywords "probiotics, postbiotics, proteome, proteomics, biofilm, antibiotic resistance" in the Web of Science, PubMed, Medline, and Scopus databases. All articles related to experimental studies were included in the study and articles that did not contain the full text were excluded.

To study microbial macromolecules, in addition to genomic methods, there are also proteomic methods that provide information about the structural and functional proteins of bacteria. In the scope of bacterial proteomics studies, in addition to pathogenic bacteria, probiotic bacteria are also mentioned, which are part of the structure of this Microorganisms, as well as due to their metabolic activity, produce compounds known as postbiotics, which are responsible for their beneficial effects and have various properties, including antimicrobial, anti-inflammatory and immune system modulating effects.

Utilizing applied proteomics in the field of proteomic profile analysis of bacteria, particularly probiotics can be considered a new approach towards the comprehensive knowledge of postbiotic metabolites, which is the basis for the enrichment of the food matrices for the development of functional foods for health-promoting objectives.

Laboratory courses have a special importance in developing of medical students' Practical skills. The aim of this study was to comparison of logbook and traditional Laboratory worksheet in teaching and evaluating of Bacteriology courses in accoedance with the educational objectives.

The students were divided into control and experimental groups. The logbook for practical courses in bacteriology was designed according to the lesson plan and course plan. Then, the students of the intervention group were evaluated by completing the logbook. Students' satisfaction and learning at the end of the semester in the two groups were compared using independent t-test.

Bacteriology course scores were no statistically significant difference between the control and experimental groups (P = 0.137). Satisfactory level in all areas was high to very high.

According to the analysis of the results of the satisfaction questionnaire, The use of the laboratory log book, causes clarification of educational objectives, classified information, encouraging students to search for scientific materials related to subjects, increasing active learning, and more interaction between students and teacher.

One of the most important elements in SPICES model is student-centered education. Taking notes is one of the simplest ways to increase student interaction and participation in learning. The purpose of this project was to design, implement, and evaluate an active-interactive education model in teaching the bacteriology course.

This project was carried out in three stages including design, implementation and evaluation. At the design stage, the outline of the program was determined through meetings with faculty members from Microbiology and Infectious Diseases departments; the curriculum-based workbook was designed based on a mind map form; then, teaching was based on the workbook and student participation in the classes. Finally, project evaluation was done by completing the evaluation form by students and then statistical analysis was performed.

Statistical results comparing the students of Medicine and Laboratory Science showed the highest student satisfaction with using book and suggestion of using book for other courses, and least satisfaction with graphical suitability and structural design in both groups. Significant differences between the two groups were found to be statistically significant for the students of Medicine compared to the students of the Laboratory Science (p = 0.049).

The use of filling-out form textbooks has an important role in enhancing studentschr('39') interaction and participation in Medical Bacteriology education. It is suggested that a similar structure to this book be explored to teach other Microbiology courses.

Adenoid hypertrophy and its complications such as otitis media and sinusitis are common problems in childhood. Rapid and appropriate detection of interfering microorganisms in chronic nasopharyngitis is very important for better medical and surgical interventions. The aims of this study were to detect major core adenoidal microorganisms and to compare similarity of pernasal and oropharyngeal cultures with adenoidal culture, and also to compare bacteriological resistance in patients with and without complications. In this descriptive study, 50 patients with adenoid hypertrophy and chronic nasopharyngitis were recruited and divided into 2 groups: group I (n=25) with complications such as otitis media with effusion and group II (n=25) without complication. All patients underwent adenoidectomy. A pressure equalizing tube was inserted for patients in group I. The smear and culture specimens were collected for bacteriological study. After 26 months of prospective bacteriological study on 50 patients with adenoidal enlargement, major results were as follow: the most common adenoidal growing microorganisms in two groups of patients, in decreasing frequency were hemophilus influenza, type B beta hemolytic streptococcus and staphylococcus auresus. Pernasal smear and culture results were more similar than oropharyngeal results to core adenoidal cultures (p<0.01). 70.1% of adenoidal microorganisms in group I patients and 21.2% in group II patients were resistant to ordinary antibiotics (without anti-betalactamase activity) (P<0.0001). For better medical management of chronic nasopharyngitis (pre and/or post adenoidectomy), we recommend that in antibiotic selection, the hemophilus influenza type B should be considered as the major growing organism. Pernasal culturing is more appropriate for detection of interfering microorganisms. In complicated patients (cases of otitis media with effusion and/or sinusitis) it is advisable to use more potent antibiotics with anti-betalactamase activity. For infection control in non-complicated patients, use of ordinary antibiotics can reduce the resistance to potent antibiotics in general population.

Nosocomial infection is an increasing problem. The global problem of antimicrobial resistance is particularly pressing in developing countries, where the infectious disease burden is high and cost constraints prevent the widespread application of newer, more expensive agents. In a prospective study, 203 consecutive cases with hospital-acquired infection in a university hospital in Bushehr port were evaluated. The most common hospital-acquired infection was urinary (76 cases), conjunctivitis (16 cases), bacteremia (8 cases), meningitis (5 cases), wound (3 cases), empyema (2 cases) and peritonitis (1 case). The patients with hospital-acquired infection were from surgical and internal medicine I.C.Us (53.2% & 15.6%, respectively). The most frequent isolated organisms were Pseudomonas aeruginosa (25.6%), Acinetobacter baumannii (19.7%), E. coli (13.3%), Klebsiella pneumoniae (11.3%), Staphylococcus aureus (8.4%), Staphylococcus epidermidis (7.9%), Enterobacter species (7%), Streptococcus species (6.4%), and Proteus mirabilis (0.5%). The most resistant organisms to antimicrobial agents were Acinetobacter baumannii and Pseudomonas aeruginosa 97 & 93.3% of these bacteria were resistant to third generation cephalosporins. The isolated Staphylococcal species were resistant to amikacin (94%). In conclusion, gram negative bacteria were the most common etiologic agent of hospital-acquired infection and had a high level of resistance to amikacin and third generation cephalosporins. Therefore, new therapeutic strategies should be designed to combat these microorganisms.