جستجوی مقالات مرتبط با کلیدواژه "burn injury" در نشریات گروه "پزشکی"

A burn tissue injury is one of the most severe forms of trauma which results in severe life-threatening disturbances. Burn injury has many morbid complications, so it needs a multi-disciplinary care team according to the burn center to reduce its mortality and morbidity.

This article aims to review drawbacks and complications associated with the burning injury including Acute Kidney Injury (AKI), Acute lung injury, Heart Failure, Electrolyte imbalance, intra-abdominal hypertension in children and adult burn patients, and recent challenging treatments.

Improved understanding of the pathophysiology of burn-induced complications can contribute to organizing a well-treatment plan, which leads to improved outcomes.

Herein, the evidence available on the management of all burn induced-complications is summarized.

Abstract

Recently, a fat injection procedure called lipofilling has been widely used for many skin pathologies. So far, limited studies have examined the use of fat injections to treat burn scars. Given the importance of burn wounds and their psychological, social and economic burden, in this study, we compared the effect of Lipofilling on the healing of burn scars.

In this study, people who underwent burn scar lipofilling in the plastic surgery clinic between April 2020 and April 2021 were included in the study. The primary information of the patients was collected. Then, visits were made on days 30, 90, and 180, and the size, color, and symptoms of the scar were recorded in each visit.

The results showed that 65% of the patients were satisfied with the treatment. In 75% of the subjects, a high effect of lipofilling was observed and in 20%, a moderate effect was observed in the healing of burn wound color. The mean overall resizing of the burn scar was 8.65 mm. The average size of a burn scar after one month was 2.98 mm. The average size change after the third month compared to the first month was 3.65 mm and in the sixth month compared to the third month it was 2.1 mm.

The results showed that the lipofilling method of fat injection had a high effect in reducing the size and improving the color of burn scars. It is suggested to conduct studies with a higher sample size and multicenter.

Despite advances in burn care and management, infections are still a major contributor to morbidity and mortality rates in patients with burn injuries. Regarding this, the present study was conducted to investigate the prevalence and importance of candidemia in pediatric burn patients.

Blood samples were collected from the patients and cultured in an automated blood culture system. Candida species were identified using specific culture media. The relationship between candidemia and possible risk factors was evaluated and compared to a control group.

A total of 71 patients with the mean age of 4.52±3.63 years were included in the study. Blood cultures showed candidemia in 19 (27%) patients. Based on the results, C. albicans was the most common fungus among patients with and without candidemia. The results of statistical analysis also showed that candidemia was significantly correlated with total body surface area (TBSA), mechanical ventilation, duration of total parenteral nutrition, length of intensive care unit (ICU) stay, presence of neutropenia, and R-Baux score (all P≤0.001). In this regard, TBSA, length of ICU stay, R-Baux score, and Candida score were identified as the determinant factors for mortality due to candidemia.

Candidemia increases the mortality and morbidity rates associated with burn injuries. Prompt diagnostic and prevention measures can reduce the unfortunate outcomes via controlling the possible risk factors.

burn injury remains as a major medical problem throughout the world. This injury is accompanied with inflammatory and wound healing responses. Since Royal jelly (RJ) has anti-inflammatory and wound healing activity therefore, the aim of this study was to evaluate the repairing effects of RJ on skin burn- damage.

In an experimental study, 40 male wistar rats (8 weeks old) were engaged. The animals were divided into five equal groups. Group 1 was considered healthy control. Group 2 (positive control) was treated topically with Silver Sulfadiazine Cream, group3 received Eucerin as negative control, and group 4, 5 treated with RJ (10 and 30%).
Sampling was performed after observing the second-degree burns on the first, seventh and fourteenth days.  Then after 28 days, rats were sacrificed and their skin tissues were used for morphological and morphometric assessments.

The results of this study showed that the amount and arrangement of collagen type 1 protein was higher in the RJ treatment groups versus control group.
Reconstruction and thickening of the epithelium in RJ treated groups confirmed therapeutic effects of RJ. In addition, RJ increased angiogenesis compared to the control group. The woundchr(chr('39')39chr('39'))s surface area was reduced in the RJ treatment groups compared to the control group. In addition, Fibroblast cell proliferation was increased in the groups receiving RJ versus control.

It could be concluded that, RJ induce wound healing effects and might be considered as potential treatment option to improve the burn wound healing.

The skin of newborns is very thin and sensitive to burns. In this age group, the mortality rate is very high. Burns account for approximately 2 million injuries annually in the United States alone out of which 500,000 cases need medical treatment and 100,000 cases require hospitalization. This study aimed to determine the incidence and magnitude of the injury, mortality rate, and causative agent in newborns and neonates within the first 6 months of life admitted to a burn unit.

The documents of all burned infants admitted to Imam Reza hospital of Mashhad, Iran, were retrospectively analyzed within 2001-2011.

A total of 447 burns were admitted to this ward for 10 years. Twenty-five (6%) cases were in the first 6 months of life. Three (12%) cases were newborns (within the first 28 days of life). In addition, 15 (60%) cases were female. The mean age on admission was 5.3±1.2 months (a minimum of 3 days and maximum of 6 months). The mean total body surface area of burns was 23±15 percentile. The duration of hospital stay was 14±18 days, and the mortality rate was 12%. The source of burns was hot water (e.g., tea) and fire with 80% and 16%, respectively. Moreover, one (4%) case was a newborn that burnt in lower extremities due to the malfunction of the incubator.

The results of this study were the same as the findings of the studies conducted around the world. Hot water and fire were the most frequent sources of burns. Furthermore, females were injured more frequently than males.