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عضویت

جستجوی مقالات مرتبط با کلیدواژه « colic » در نشریات گروه « پزشکی »

  • Reihaneh Montazeri, Shirin Hasanpour*, Mojgan Mirghafourvand, Mohammad Asghari Jafarabadi, Manizheh Mostafa Gharehbaghi, Soheila Bani
    Introduction

     Infant colic, causing excessive crying, poses anxiety for parents and a challenge for pediatricians and nurses. The Infant Colic Scale (ICS) serves to assess the severity and causal factors of colic. Despite its significance, the psychometric properties of ICS have not been evaluated in the Iranian population. This study seeks to address this gap by assessing the psychometric properties of ICS in Iran.

    Methods

     A sample of 220 mothers with 2–16-week-old term infants diagnosed with infantile colic was selected through convenience sampling. Following forward and back-translation, the face validity, content validity, and construct validity of ICS were systematically evaluated. Reliability was examined through both internal consistency (Cronbach’s alpha) and test-retest stability methods.

    Results

     Content validity index (CVI) and content validity ratio (CVR) values for ICS were 0.94 and 0.81, respectively. The good fit indices confirmed the validity of the five-factor structure. Cronbach’s alpha coefficient and intraclass correlation coefficient (ICC) were 0.71 and 0.94, respectively.

    Conclusion

     The Persian version of ICS is a valid and reliable tool, suitable for assessing infantile colic in the Iranian population. Future studies and clinical practice can utilize this tool to identify major causes of this disorder in the Iranian context.

    Keywords: Infant, Colic, Psychometric, Iran}
  • نازنین حنفی بجد*، سید علی معزی بادی

    درد غیرمعمول قفسه سینه اغلب در زنان مسن مبتلا به دیابت، فشار خون بالا و بیماری های قلبی مشاهده می شود. تاکنون برخی از تظاهرات غیرمعمول انفارکتوس میوکارد گزارش شده است که شامل گوش درد، درد پهلو، خستگی، گردن درد، تهوع و استفراغ، تنگی نفس و درد شانه است. ما در این مقاله یک مورد از علایم نادر بیماری قلبی عروقی را با علایم ارجاعی از جمله درد کولیک شکمی گزارش می نماییم. بیمار مردی 55 ساله با سابقه دیابت و تحت درمان با انسولین بود که به مدت دو روز دچار دردکولیک، تندرنس دوره ای اپی گاستر و تهوع و استفراغ مکرر شده بود. در ابتدا مشکوک به پانکراتیت بود؛ اما با توجه به این که سطح آنزیم آمیلاز و لیپاز نرمال بود و شواهدی مبنی بر وجود مایع آزاد شکمی و لگنی با توجه به نتایج سونوگرافی مشاهده نشد؛ فرضیه پانکراتیت رد شد. بیمار علی رغم نرمال بودن نوار قلب اولیه تا شب قبل از ویزیت توسط متخصص قلب، درد شدیدتری را تجربه کرد و بنابراین تا پایان همان شب به بخش داخلی قلب ارجاع شد که پس از آنژیوگرافی مشخص گردید که شاخه OM1 (Obtuse Marginal) عروق کرونری تنگی شدید (90-99%) دارند. یکی از تظاهرات غیرمعمول انفارکتوس میوکارد، تندرنس شکمی و درد کولیک است. در بیمارانی که عوامل خطر قلبی مانند دیابت و بیماری مزمن کلیه دارند؛ بایستی تظاهرات غیرشایع علی رغم وجود نوار قلب طبیعی بررسی گردد.

    کلید واژگان: انفارکتوس میوکارد, درد قفسه سینه, کولیک}
    Nazanin Hanafi Bojd*, Seyed Ali Moezi Bady

    Unusual chest pain is often observed in older women with diabetes, high blood pressure, and heart disease. Some unusual manifestations of myocardial infarction have so far been reported, including earache, flank pain, fatigue, neck pain, nausea and vomiting, shortness of breath, and shoulder pain. In this article, we report a case of rare symptoms of cardiovascular disease with referral symptoms, including abdominal colic pain. The patient was a 55-year-old man with a history of diabetes under treatment with insulin who had abdominal colic pain, periodic epigastric tenderness, and frequent nausea and vomiting for 2 days. At first, he was suspected of pancreatitis, but considering that his amylase and lipase enzymes were normal and no evidence of the existence of free abdominal and pelvic fluid was observed according to ultrasound results, the hypothesis of pancreatitis was rejected. Despite the normality of the initial ECG until the night before the visit by the cardiologist, the patient experienced more severe pain and, as a result, was referred to the cardiac internal ward until the end of the same night, after angiography, it was found that the obtuse marginal (OM1) branch of coronary arteries had severe narrowing (90-99%). Abdominal tenderness and colic pain are among the unusual manifestations of myocardial infarction. In patients with cardiac risk factors, such as diabetes and chronic kidney disease, despite the existence of a normal ECG, uncommon manifestations should be checked.

    Keywords: Myocardial Infarction, Chest Pain, Colic}
  • Zahra Sahebkaram, Reza Bahrami, Sara Azima, Marzieh Akbarzadeh *
    Background

    Too much crying is a self‑limiting problem and disappears within a few weeks. However, it can lead to maternal depression and parental stress. This study aimed to evaluate the effect of lavender oil inhalation on the duration of night crying within a week of intervention among infants with infantile colic.

    Methods

    In this double‑blind randomized clinical trial, the inclusion criteria for infants were being healthy, not taking any medications for colic, having an episode of crying two hours a day, and having a healthy mother. The intervention group received lavender oil inhalation and the control group received sweet almond oil inhalation for seven days. The data pertaining to the duration of crying were collected four times a day (morning, afternoon, evening, and night) via telephone contact. Mothers’ mood scores were also assessed at the beginning of the study and on the seventh day of the intervention.

    Results

    At first, the two groups were not different in terms of the duration of crying. After the intervention, however, a significant difference was observed in this regard on all seven days of the study (P < 0.001). Based on the results of the repeated measures analysis, the difference between the two groups was statistically significant (P < 0.001).

    Conclusions

    The results showed that inhalation of lavender oil at low concentrations could reduce colic symptoms and improve maternal mood.

    Keywords: Aromatherapy, colic, crying, infant, lavender oil, night}
  • Sara Sadeghzadeh Fard Sorkhabi, Mohammad Kazemian, AhmadReza Shamshiri
    Purpose

    This study aimedto investigate the role of non-pharmacological method of breastfeeding and maternal nutrition in the treatment of infantile colic in order to reduce the role of pharmacological method.

    Methods

    This study was a double-blinded clinical trial study on 62 infants less than 4 months of age referred to Emergency ward of Mofid Hospital in 2014. The infants were randomly divided into two groups that one group received routine colic treatment without any intervention (as the control group) and the other group received hypoallergenic lactation and also were trained on how to breastfeed appropriately. On the second and tenth days, all mothers were contacted and the duration of crying and restlessness of the infant was assessed.

    Results

    The severity of colic significantly lower in intervention group as compared to control group on the second and tenth days of intervention. In this regard, the mean change in severity of colic at the end of assessment was 2.4 ± 2.2 in intervention group and 0.7 ± 1.5 in control group (p < 0.001). The mean change in colic intensity in subgroups with complete, partial and low adherence was 4.1 ± 2.4, 2.5 ± 1.6, and 0.2 ± 1.6 respectively indicating a significant difference (p <0.001).

    Conclusion

    Comprehensive mothers' training on how to breastfeed and determine the best breastfeeding position along with the change in nutritional habit can significantly reduce colic severity.

    Keywords: Colic, Breastfeeding, Nutrition}
  • فائزه خنجریان، اکرم سادات حسینی*
    مقدمه و هدف

    کولیک بیماری شایع دوره شیرخوارگی است که بر سلامت روحی- روانی والدین اثر دارد. این مطالعه با هدف بررسی ارتباط بین کیفیت زندگی والدین با کولیک شیر خواران و دیدگاه اسلام در اینمورد انجام شد.

    روش

    مطالعه مقطعی- مقایسه ای در سال 99-1398در بیمارستان مرکز طبی کودکان بر روی والدین شیر خوارانی که دچار کولیک شیر خواری بودند به عنوان گروه مورد و گروه مقایسه والدین شیر خوارانی که فاقد کولیک شیر خواری بودندانجام شد. داده ها با استفاده از چک لیست دموگرافیک والدین و پرسش نامهی SF-36 جمعآوری شد. اطلاعات با آزمونهای توصیفی و تحلیلی تجزیه و تحلیل شد.

    نتایج

    کیفیت زندگی در دو حیطه بهزیستی هیجانی (015/0P=) و درد (017/0P=) در مدل رگرسیونی معنی دار شد. با افزایش یک واحد بهزیستی هیجانی شانس ابتلای شیر خوار به کولیک 3 درصد کاهش و باافزایش یک واحد درد شانس ابتلای شیر خوار به کولیک 1درصد افزایش مییابد. همچنین با افزایش یک سال سن مادر شانس ابتلای شیر خوار 7 درصد کاهش مییابد. شانس ابتلا به کولیک مادرانی که مصرف چای دارند 30 برابر بیشتر است. کیفیت زندگی در حیطه انرژی- خستگی در مدل رگرسیونی معنادار شد و در مادران دارای شیر خواران کولیکی 3 درصد کمتر بود.

    نتیجه گیری

    با توجه به نتایج و آموزه های غنی اسلام در اینمورد ارایه دهندگان خدمات سلامتی می توانند با پیشنهادهای عملکردی و مبتنی بر زیر ساختهای فرهنگی و دینی در جهت کاهش استرس مادران باردار اقدام نمایند و در نتیجه امکان طی دوره بارداری را برای آن ها با آرامشی بیشتر فراهم نمایند.

    کلید واژگان: کولیک, کیفیت زندگی, والدین, سبک زندگی اسلامی}
    Faezeh Khanjarian, Akram Sadat Sadat Hoseini *
    Introduction & aim

    Colic is a common disease of infancy that affects the mental health of parents. The aim of this study was to investigate the relationship between parents' quality of life and infant colic and Islam's view on this issue.

    Method

    A cross-sectional comparative study was performed on the parents of infants with infantile colic in the hospital of the Pediatric Medical Center in 2009-2010. As a control group, comparisons were made with the parents of infants who did not have infantile colic. Data were collected using a parent demographic checklist and the SF-36 questionnaire. Data were analyzed by descriptive and analytical tests.

    Results

    Quality of life in two areas of emotional rehabilitation (P = 0.015) and pain (P = 0.017) was significant in the regression model. Increasing one unit of emotional rehabilitation decreases the infant's chances of developing colic by 3%, and increasing one unit of pain increases the infant's chances of developing colic by 1%. Quality of life in the area of energy-fatigue was significant. In Islamic view the healthy life style is affected on children’s health and the best way for health promotion of child is Islamic life style.

    Conclusion

    According to the results and valuable order in Islamic view, health care providers can reduce the stress of pregnant mothers with functional suggestions based on cultural and religious infrastructures, and as a result, provide them with more relaxation during pregnancy.

    Keywords: Colic, quality of life, Parent, Islamic life style}
  • Mahbobeh Firooz, Fereshteh Eidy, Zohreh Abbasi, Seyed Javad Hosseini*

    Context:

     Infantile Colic (IC) is an essential problem in infancy that is influenced by factors related to infants and parents. The parental factors associated with colic have not been comprehensively assessed. 

    Objectives

    The present systematic review was conducted to investigate the parental factors affecting the incidence of IC.
    Data Sources: Databases, including PubMed, Web of Science, Scopus, Science Direct, Google scholar, as well as Scientific Information Database (SID), and Magiran (Iranian websites) were searched to identify all eligible papers concerning parental factors affecting infantile CI. The registration number of this study was CRD42020163518 in the PROSPERO database.

    Study Selection:

     A total of 423 relevant articles published up to the end of December 2019 were assessed. The selected articles were screened based on duplicated, eligibility criteria, and quality appraisal. The main inclusion criteria were observational studies and articles in Persian and English languages.

    Data Extraction: 

    The Mesh keywords and Boolean operators included (“risk factors” OR “causality”) AND (“parents” OR “fathers” OR “mothers”) AND (“infant”) AND (“colic”). Consequently, 18 papers were thoroughly studied and the related data were extracted. Two researchers independently performed the data extraction and quality assessment based on the STROBE checklist from the observational studies. The information of selected studies was recorded in a table, i.e. consisted of authors’ names, purpose, design, population, and main results.

    Results

    Final articles consisted of 10 prospective, 6 cross-sectional, and 2 case-control studies. Eventually, the effective factors were placed in 6 categories, as follows: psychological factors, physical factors, taking medications, perinatal factors, family’s socioeconomic status, and maternal diet. The most important characteristics predisposing to IC were parental depression, anxiety, smoking, maternal history of migraine, young age, primiparity, low family support, high socioeconomic status, high-risk pregnancies, and delivery, taking antibiotics, as well as the consumption of celery, onions, and bananas.

    Conclusions

    Various parental factors affect the incidence of colic. Identifying these risk factors and accurate planning can be beneficial in the prevention and treatment of IC.

    Keywords: Risk factors, Infant, Causality, Colic, Parent}
  • Sara Sadeghzadeh Fard Sorkhabi*, Mohammad Kazemian, Ahmad Reza Shamshiri
    Aims

    We decided to investigate the role ofnon-pharmacological method of breastfeeding and maternal nutrition in the treatment of infantile colic in order to reduce the role of pharmacological method.Materials and

    Methods

    This study was a double-blinded clinical trial study on 62 infants less than 4 months of age referred to Emergency ward of Mofid Hospital in 2014. The infants were randomly divided into two groups that one group received routine colic treatment without any intervention (as the control group) and the other group received hypoallergenic lactation and also were trained on how to breastfeed appropriately. On the second and tenth days, all mothers were contacted and the duration of crying and restlessness of the infant was assessed.

    Results

    The severity of colic significantly lower in intervention group as compared to control group on the second and tenth days of intervention. In this regard, the mean change in severity of colic at the end of assessment was 2.4 ± 2.2 in intervention group and 0.7 ± 1.5 in control group (p < 0.001). The mean change in colic intensity in subgroups with complete, partial and low adherence was 4.1 ± 2.4, 2.5 ± 1.6, and 0.2 ± 1.6 respectively indicating a significant difference (p < 0.001).

    Conclusion

    Comprehensive mothers' training on how to breastfeed and determine the best breastfeeding position along with the change in nutritional habit can significantly reduce colic severity.

    Keywords: Colic, Breastfeeding, Nutrition}
  • علی شیدایی، علیرضا ابدی *، فاطمه ناهیدی، فرزانه امینی، فرید زایری، نفیسه گازرانی
    زمینه و هدف

    در مطالعات آماری، به منظور بررسی ارتباط بین متغیرها از مدل های آماری استفاده می شود. با توجه به تنوع مدل های آماری پیدا کردن مناسب ترین مدل کار پیچیده ای است. این مطالعه با هدف مقایسه مدل های مختلف در بررسی درمان کولیک شیرخواران و تاثیر بد مشخص سازی انجام شد.

    روش بررسی

    این کارآزمایی بالینی تصادفی شده در درمانگاه اطفال بیمارستان امیرکبیر اراک، بر روی 100 شیرخوار مبتلا به کولیک به صورت تصادفی و در دو گروه مداخله و کنترل انجام شد. جمع آوری و تحلیل داده ها در سال 1395 انجام شد. پس از آموزش ماساژ به مادران گروه مداخله، از آن ها خواسته شد روزی سه بار در طول هفته ماساژ را بر روی شیرخواران انجام دهند و در گروه کنترل با تکان دادن شیرخوار، علایم کولیک را برطرف کنند. در هر گروه، والدین روزانه تعداد و شدت گریه کودکان را در چک لیست مربوطه ثبت نمودند. در نهایت، با به کارگیری مدل های مختلف و نرم افزارهای R، SAS و معیارهای نیکویی برازش بهترین مدل معرفی شد.

    یافته ها:

     در گروه ماساژ میانگین شدت گریه شیرخواران مبتلا به کولیک از 01/5 در روز نخست به 47/2 واحد در روز هفتم کاهش پیدا کرد. از روز چهارم به بعد شیرخواران گروه ماساژ میانگین مدت زمان خواب بالاتری را دارا بودند. همچنین شدت گریه در شیرخواران گروه ماساژ به طور معناداری بیشتر از گروه تکان به دست آمد. در خصوص برازش مدل های حاشیه ای، ساختار همبستگی خودبازگشتی مرتبه اول بهترین برازش و برای برخی از متغیرها مدل اثرات تصادفی با توزیع گاما برای مولفه تصادفی برازش بهتری داشته است.

    نتیجه گیری:

     ماساژ می تواند باعث کاهش کولیک شیرخواران گردد. ازنظر آماری نیز در صورت بدمشخص سازی مدل غیرخطی، واریانس برآوردها بیش از مقدار برآورد شده تحت تاثیر بدمشخص سازی ساختار همبستگی قرار می گیرند.

    کلید واژگان: کولیک, ماساژ, مدل های آمیخته, مدل های غیرخطی}
    Ali Sheidaei, Alireza Abadi*, Fatemeh Nahidi, Farzaneh Amini, Farid Zayeri, Nafiseh Gazrani
    Background

    Statistical models are used to investigate the relationship between variables in statistical studies. Considering the variety of statistical models, finding the most suitable model is a complex work. This study aimed to compare different models in the treatment of infantschr('39') colic and the misspecification of specificity.

    Methods

    This randomized clinical trial was conducted on 100 infants with colic in the pediatric clinic of Amir Kabir Hospital in Arak, the intervention and control groups were randomly divided into two groups. The collection and analysis of the data was performed in 2016. After teaching massage to mothers of the intervention group, they were asked to perform massage on infants three times a day during the week. In the control group, mothers can relieve the symptoms of colic by shaking the infant. Parents recorded the number and severity of crying daily in the checklist. Finally, by using different models, R software, SAS, and goodness of fit, the best model was introduced.

    Results

    In the massage group, the mean crying intensity of infants with colic decreased from 5.01 units on the first day to 2.47 units on the seventh day. On the other hand, the difference in mean sleep time changed from 1.81 hours in favor of the shaking group on the first day to 1.26 hours in favor of the massage group on the seventh day. Also, the severity of crying in the infants of the massage group was significantly higher than the impulse group. Regarding the grace of marginal models, the first-order self-return correlation structure was the best grace and for some variables, the model had random effects with a gamma distribution for the random component.

    Conclusion

    Massage can reduce infantschr('39') colic. Statistically, in the case of a nonlinear model, the variance of estimates is more than estimated to be influenced by the misspecification of the correlation structure.

    Keywords: colic, massage, mixed models, nonlinear models}
  • رضا دریکوندی*
    زمینه و هدف

    در سال 431 ق خاندان ترک تبار سلجوقی موفق شدند بعد از 13 سال زورآزمایی با غزنویان، آن ها را بطور قطعی در پیکار دندانقان شکست دهند و بنیاد حکومتی را بگذارند که تا سال 590 ق استمرار یافت. در دوره 159 ساله حاکمیت سلجوقیان بر ایران، 15 تن از اعضای این خاندان به صورت رسمی به قدرت رسیدند. غالب حاکمان این دودمان، درنتیجه ابتلای به بیماری های گوناگون درگذشتند. برخی از آنان نیز در جریان منازعات داخلی به منظور کسب قدرت، یا در روند مقابله با دشمنان خارجی سلطنت، کشته شدند. به جز چند استثنا، مرگ هر دو گروه و به ویژه سلاطینی که به مرگ غیرطبیعی درگذشتند، در سنین پایین رخ داد. این مسئله موجب شد که اکثر حاکمان این دودمان، سلطنت ناپایداری داشته باشند. در پژوهش پیش رو تلاش شده، چگونگی مرگ سلاطین سلجوقی و نسبت میان نوع مرگ این حاکمان، با مدت زمامداری و حیات آنان، مورد بررسی قرار گیرد.

    مواد و روش‌ها

    در پژوهش حاضر با استفاده از روش آماری، مهم ترین منابع عصر سلجوقی در جهت دستیابی به اهداف تحقیق، مورد بررسی و تجزیه و تحلیل قرار گرفته است.

    یافته‌ها

    اغلب سلاطینی که به مرگ طبیعی فوت کردند، سابقه ابتلا به امراض متعددی را داشتند؛ اما در نتیجه ابتلا به یک بیماری خاص فوت کردند. مهم ترین این بیماری ها عبارت بودند از قولنج، بواسیر، سل، تب محرقه، آبله، رعاف و امراض مقاربتی. گروهی که به مرگ غیرطبیعی درگذشتند، نیز بعضا سابقه ابتلا به برخی از امراض را داشتند؛ با این حال پیش از آنکه در نتیجه بیماری فوت کنند، توسط مخالفان و رقبای خود کشته شدند. طول عمر و دوام سلطنت آن دسته از حاکمانی که به مرگ طبیعی درگذشتند، بیشتر از گروه دوم بود.

    ملاحظات اخلاقی

    در فرایند انجام این پژوهش، ضمن رعایت اصل امانت داری در استفاده از منابع، از ارایه تحلیل های غیرعلمی و مغرضانه خودداری شده است.

    نتیجه‌گیری

    از میان 15 سلطان سلجوقی، 10 تن به علت ابتلا به امراض گوناگون درگذشتند. بیماری قولنج با سه مورد، بیماری های سل و تب هر کدام با دو مورد و سایر امراض با یک مورد، باعث مرگ این گروه از سلاطین شدند. میانگین عمر این گروه 38 سال و میانگین سلطنت آنان 15.3 سال است. اگرچه از میان پنج سلطان دیگر سلجوقی، دو تن دارای بیماری قبلی بودند، اما هر پنج تن به مرگ غیرطبیعی و توسط مخالفانشان کشته شدند. سه تن آنان توسط مدعیان قدرت مسموم شدند و دو سلطان دیگر در نبرد با مخالفان خارجی سلطنت به زخم شمشیر به قتل رسیدند. میانگین عمر این گروه 36 سال و میانگین سلطنت آنان 9.03 سال بود.

    کلید واژگان: قولنج, سلجوقیان, تب, بواسیر, غلامبارگی, آبله}
    Reza Derikavandy*
    Background and Aim

    In 431 AH, after a 13-year struggle with the Ghaznavids, the Seljuk Turkic dynasty succeeded in defeating them decisively in the battle of Dandanqan and laying the foundation of a government that lasted until 590 AH. During the 159 years of Seljuk rule in Iran, 15 members of this dynasty officially came to power. Most of the rulers of this dynasty died as a result of various diseases. Some of them were killed during internal conflicts in order to gain power or in the process of confronting the foreign enemies of the monarchy. With a few exceptions, the deaths of both groups, and especially of the sultans who died an unnatural death, occurred at a young age. This caused most of the rulers of this dynasty to have an unstable monarchy. In the present study, an attempt has been made to study the manner of death of the Seljuk sultans and the relationship between the type of death of these rulers and their reign and life.

    Materials and Methods

    In the present study, using statistical methods, the most important sources of the Seljuk era have been studied and analyzed in order to achieve the objectives of the research.

    Findings

    Most kings who died a natural death had a history of various diseases; but they died as a result of a certain disease. The most important of these diseases were colic, hemorrhoids, tuberculosis, inflammatory fever, smallpox, diarrhea and sexually transmitted diseases. The group that died of abnormal deaths also sometimes had a history of certain diseases; however, before they died of the disease, they were killed by their opponents and rivals. The lifespan of those rulers who died a natural death was longer than the second group.

    Ethical Considerations

    In the process of conducting this research, while observing the principle of fidelity in the use of resources, non-scientific and biased analyzes have been refused.

    Conclusion

    Out of 15 Seljuk sultans, 10 died due to various diseases. Colic with three cases, tuberculosis and fever with two cases each and other diseases with one case, caused the death of this group of kings. The average age of this group is 38 years and their average reign is 15.3 years. Although two of the other five Seljuk sultans had a previous illness, all five were killed abnormally by their opponents. Three of them were poisoned by the claimants to power, and two others were killed by swords in battle with foreign opponents of the monarchy. The average age of this group was 36 years and their average reign was 9.03 years.

    Keywords: Colic, Seljuk, Fever, Hemorrhoids, Slavery, Smallpox}
  • زهرا اکبریان راد، زینب کفشگر، ثریا خفری، رقیه خداداد هتکه پشتی، زهره برزگر، محسن حق شناس مجاوری*
    زمینه و هدف

    کولیک شیرخوارگی با ایجاد دلپیچه و بیقراری در شیرخوار سبب اضطراب و نگرانی بسیاری از والدین می گردد. این مطالعه به منظور تعیین فراوانی کولیک شیرخوارگی و عوامل مستعد کننده آن در شهر بابل انجام شد.

    روش بررسی

    این مطالعه توصیفی - تحلیلی مقطعی روی 591 شیرخوار (321 دختر و 270 پسر) در مرکز آموزشی درمانی آیت الله روحانی وابسته به دانشگاه علوم پزشکی بابل طی سال های 97-1395 انجام شد. نوزادان با وزن 2500 تا4000 گرم و سن بیشتر یا مساوی 37 هفته بدون مشکلات زمینه ای وارد مطالعه شدند و در هفته های 2، 4، 8 و 12 توسط یک فوق تخصص نوزادان تحت معاینه قرار گرفتند. شیرخواران بر اساس شکایت والدین و معیار Wessel در سه گروه دلپیچه با گریه (کولیکی) گروه دلپیچه بدون گریه و گروه بدون علامت تفکیک شدند. سپس عوامل خطر کولیک در سه گروه مورد مقایسه قرار گرفت.

    یافته ها: 

    45.5 درصد از نوزادان دلپیچه همراه با گریه (کولیک) داشتند. زمان بیقراری به طور معنی داری در هنگام شب بیشتر از صبح و عصر بود (P<0.05). همچنین در متولد شدگان به روش زایمان سزارین فراوانی کولیک بیشتر بود (P<0.05). از لحاظ پاریتی به طور معنی داری در فرزند اول بیشتر از سایر فرزندان تظاهرات کولیک مشاهده شد (P<0.05). بین متغیرهای جنسیت، سطح تحصیلات مادر، سردرد مادر، سابقه مصرف دخانیات توسط والدین و مصرف لبنیات در مادر با کولیک شیرخوارگی ارتباط آماری معنی داری مشاهده نشد.

    نتیجه گیری: 

    علایم کولیک در نزدیک به نیمی از نوزادان وجود دارد و در فرزندان اول، شیرخواران به دنیا آمده به روش سزارین و هنگام شب بیشتر بروز می نماید.

    کلید واژگان: نوزاد, کولیک, گریه}
    Zahra Akbarian Rad, Zeynab Kafshgar, Soraya Khafri, Roghayeh Khodadad Hatkeposhti, Zohreh Barzegar, Mohsen Haghshenas Mojaveri*
    Background and Objective

    Infantile colic which can cause nervousness and anxiety in parents by fussing and restlessness in babies. This study was done to determine the prevalence and associated risk factors of infantile colic in Babol, the North of IRAN.

    Methods

    This descriptive-analytical study was done on 591 breastfeeding babies (321 females, 270 males) born with birth weight 2500-4000 grams and gestational age ≥37 weeks without any medical problem during 2016-18. They visited in age 2, 4, 8, 12 weeks by neonatologist. On the basis of parents complain and Wesselchr('39')s criteria babies were divided into three groups: Cramp with crying (colicky group), Cramp without crying and normal group. Then possible risk factors of infantile colic have been compared in three groups.

    Results

    45.5% of babies presented cramp with crying as colic group. Time of restlessness was significantly more than morning during night and afternoon (P<0.05). Colic was higher in infants born by cesarean section (P<0.05), and in the first-born child (P<0.05). However, there was not significant relation with gender, mothers’ education, parents smoking and taking dairy product.

    Conclusion

    According to this study’s findings, nearly half of infants had the symptoms of colic, which was higher in first children, infants born by cesarean section and during night.

    Keywords: Infant, Colic, Crying}
  • Chang Hee Kim, DongSeong Shin, Tae Beom Kim*, Han Jung*
    Purpose

    To determine the efficacy of early extracorporeal shockwave lithotripsy (e-ESWL) in colic patients with ureteral stones and the patient criteria for the most effective e-ESWL.

    Materials and Methods

    335 patients who received ESWL due to ureteral stone, were divide in two groups: e-ESWL and d-ESWL by the critical cut-off point. we performed the sensitivity and specificity cut-off analyses to identified the critical cut off point. To assess the difference in the factors affecting ESWL success, univariate and multivariate logistic analyses were implemented with using variables: ESWL success; age; gender; BMI; comor - bidity; serum creatinine; stone size; stone location; stone laterality; Hounsfield unit (HU); presence of hydrone - phrosis; and presence of tissue rim. The subgroup analysis for the screened variables was conducted.

    Result

    Optimal e-ESWL was defined to occur within a 24-hour critical cut-off time. Multivariate regression anal - ysis concluded with screened variables: age, stone size, stone location, and HU, that ESWL success was 1.85-fold higher in the e-ESWL patient group. The subgroup analyses the following conditions: ≤ 65 years old by 1.784- fold; ≤10 mm stone size by 1.866-fold; mid to distal stone location by 2.234-fold; and ≤ 815 HU by 2.130-fold. When all the conditions were met, the e-ESWL success was 3.22-fold higher.

    Conclusion

    In case of colic due to ureteral stones, the patient is recommended to receive a lithotripsy within the first 24 hours. E-ESWL is recommended especially in patients who are ≤ 65 years, or with a ureteral stone HU ≤ 815, sized ≤ 10 mm, or in a mid to distal location.

    Keywords: : Extracorporeal shock wave lithotripsy, ureteral stones, colic}
  • Hassan Salehipoor, Behzad Afzali, Rahim Akram, Fereshteh Ghorat*, Zahra Niktabe, Mohammad Sahebkar
     
    Background
    The aim of this study was to evaluate the efficacy of the topical use of chamomile oil as a complementary method in the improvement of infantile colic symptoms.
    Methods
    This randomized controlled trial was carried out on 74 infants with colic at Sabzevar University of Medical Sciences in Sabzevar, Iran. The infants were randomly allocated into two groups. In the intervention group, chamomile oil was applied topically on the abdominal region three times a day for 14 days. The placebo group received paraffin oil in a similar manner. A data collection form was daily filled out for all infants by their parents. Number and duration of crying episodes and duration of sleep were assessed at the baseline and on the 7th and 14th days of the intervention.
    Results
    Results showed that there was a significant difference in the crying time of the two groups on days 7 and 14 as compared to that at the baseline (P=0.03 and P=0.002, respectively). There was a significant increase in sleep duration only on the 14th day of treatment as compared with that at the baseline (P=0.01). Although the number of crying episodes in both groups decreased, there was no significant difference between the two groups (P=0.08). Based on the regression test, although the values obtained on days 1 and 7 were not statistically significant, compared to those at the baseline, the number of crying episodes decreased on the 14th day (95% CI: -115.39 to -15.04; P=0.012).
    Conclusion
    Topical consumption of chamomile oil may be used as a complementary, safe, and cost-effective way to improve and reduce the symptoms of infantile colic.
    Keywords: Infant, Chamomile, Colic, Complementary Medicine}
  • حوا جلالی نیا، محمدعلی کیانی*، علی حق بین، معصومه سعیدی، علی خاکشور
    مقدمه
    علیرغم سالها تحقیق علمی، علت حقیقی کولیک نوزادی هم چنان نامشخص میباشد. در واقع علت کولیک نوزادی چند عاملی درنظر گرفته می شود و مشخص نشده که عوامل فیزیولوژیکی یا روانی اجتماعی مسئول ایجاد این شرایط میباشند. این مطالعه با هدف بررسی ارتباط بین متغیرهای دموگرافیک و نگرش مذهبی در مادران باردار با بروز کولیک شیرخواران انجام شده است.
    روش کار
    این مطالعه مقطعی تحلیلی بر روی 300 زن باردار مراجعه کننده به دپارتمانهای زنان و مامایی بیمارستانهای آموزشی دانشگاه علوم پزشکی مشهد انجام گردید و نوزادان این مادران بعد از تولد، از مهر 1394تا مهر 1396 از لحاظ بروز کولیک مورد بررسی قرار گرفتند. اطلاعات لازم در مورد بروز کولیک و اعتقادات مذهبی مادران توسط پرسشنامه پژوهشگر ساخت و نیز پرونده مادران باردار ونوزادان متولد شده جمع آوری گردید. داده ها با استفاده از آمار توصیفی و آزمون آماری ضریب همبستگی پیرسون در نرم افزار SPSS نسخه 20 تحلیل شد.
    یافته ها
    یافته ها نشان داد ارتباط آماری معنی داری بین نگرش مذهبی مادر باردار و سابقه کولیک در فرزندان قبلی وی با بروز کولیک در شیرخواران وجود داشت (P<0/05). بین تعداد بارداری، احساس در مورد جنین، رضایت از زندگی و مشکل در بارداری قبلی و بروز کولیک شیرخوارگی ارتباط معنی داری وجود نداشت (P>0/05).
    نتیجه گیری
    با توجه به تاثیر مثبت نگرش مذهبی مادران در کاهش بروز کولیک شیرخوارگی، توجه بیشتر به بعد معنوی وجود انسان و برنامه ریزی جهت ارتقاء آن در زنان باردار را مورد توجه قرار داد.
    کلید واژگان: کولیک, شیرخواران, زنان باردار, نگرش مذهبی}
    Havva Jalalinia, Mohammad Ali Kiani*, Ali Haghbin, Masumeh Saeidi, Ali Khakshour
    Introduction
    Despite years of scientific research, the true cause of neonatal colic is still unclear. In fact, the cause of the infantile colic is considered multi-factorial and it is not known whether the physiological or psychosocial factors are responsible for creating these conditions. The aim of this study was to investigate the relationship between demographic variables and religious attitudes in pregnant women with incidence of colic in infants.
    Methods
    This analytical cross-sectional study was performed on 300 pregnant women referred to women and midwifery departments of educational hospitals affiliated to Mashhad University of Medical Sciences. The newborn babies of these mothers from October 2015 to October 2017 were examined for incidence of colic. The information about the occurrence of colic and religious attitude of mothers was done by a researcher-made questionnaire as well as maternal case and birth case records. Data were analyzed using descriptive statistics and Pearson correlation coefficient test using SPSS software version 20.
    Results
    The findings showed that there was a significant relationship between the religious attitude of the pregnant mother and the history of colic in her offspring with colic incidence in infants (P 0.05).
    Conclusions
    Considering the positive impact of mothers' religious attitudes on reducing the incidence of neonatal colic, paying more attention to the spiritual dimension of human existence and planning to promote it in pregnant women, should be considered.
    Keywords: Colic, Economic Burden, Infants, Pregnant Women, Religious Attitudes}
  • Gholamreza Mohammadi, Masumeh Ghazanfarpour *, Leila Kargarfard, Masaudeh Babakhanian
    Context: Due to the dissatisfaction with the conventional therapeutic methods to control the infantile colic, the mothers are developing interest in herbal medicines.
    Objectives
    The present study is a systematic review with meta-analysis which was conducted to evaluate the effect of herbal medicines in the treatment of infantile colic.
    Data Sources: A systematic electronic search was performed on the databases of the MEDLINE, Scopus and the Cochrane Central Register Trials inception up to July 2018 to assess the effectiveness of herbal medicines in the treatment of infantile colic. No determined limitation was considered and the measured outcome was the duration of crying time.
    Study Selection: Six studies assessed the effect of herbal medicine on colic infantile Data Extraction: The data extraction and quality assessment of the trials were performed by two separate individuals based on standardized predefined checklist.
    Results
    Five studies investigated the effect of prepared herbal medicines containing phytoestrogens on the infantile colic, the colic improvement score, and the number of night waking times. The compounds containing phytoestrogens decreased the duration of crying time compared to placebo (SMD=-0.536; 95% CI=-0.848 to 0.224; P=0.001). Heterogeneity was moderate but not statistically significant (I2=56%; P=0.07). Moreover, one study measured the colic improvement score and the number of night wakings whose results showed a significant decrease in the parameters. To sum up, the phytoestrogens could significantly improve the infantile colic. Four trials studied the effect of compounds containing fennel, as their results indicated a significant improvement in the duration of crying time compared to control group (SMD=O.712; 95% CI=-1.005 to 0.420; P<0.001). Heterogeneity was 0% among the studies. The SMD of compounds containing fennel alone reduced the duration of crying time to less than -0.6 (95% CI= -0.940 to -0.456; P<0.001). Heterogeneity was moderate but not statistically significant (I2=0%; P=0.669).
    Conclusions
    Fennel and compounds containing phytoestrogens had a significant positive effect on the duration of crying time. Mentha piperita was shown to possess higher efficacy than simethicone in reducing daily colic duration. Further trials should be conducted with larger sample size and longer treatment duration.
    Keywords: Herbal medicines, Colic, Phytoestrogens}
  • Maryam Masaeli, Ahmadreza Khazaee, Masoud Shahabian
    Introduction
    Renal colic is an acute syndrome for which relieving the pain is known to be the best treatment. The aim of this randomized clinical trial was comparing the efficacy of intravenous ketorolac with intravenous morphine sulfate in relieving the acute pain of renal colic in patients referred to the emergency department of a tertiary care teaching hospital.
    Methods
    98 cases were selected via convenience sampling method from patients with a presumptive diagnosis of renal colic admitted in the emergency department of Besat Nahaja hospital of Tehran, Iran from March to May 2014 and randomly divided into two groups of equal size, ketorolac, and morphine sulfate. The patients’ vital signs and pain intensity were observed at baseline of the study and after 10, 30, 60, 120 and 180 minutes of drug administration. Patients were also followed for side effects. The areaunder- the-curve (AUC) was used for pain assessment. Data were analyzed in SPSS 19 using T- test, Chi-square test, and Mann-Whitney test at significance level
    Results
    Demographic and clinical characteristics of the two groups were similar before drug administration. Both drugs were equally effective in reducing pain over time (P-value = 0.17). Side effects of treatment with ketorolac, were significantly less than using morphine sulfate. The most common adverse effects caused by morphine sulfate, were dizziness and vomiting while nausea and vomiting were the most frequent side effects of using ketorolac.
    Conclusions
    Findings of this study indicated that ketorolac and morphine sulfate were equally effective in relieving the pain of renal colic, but given the severity of side effects, ketorolac is the preferred drug.
    Keywords: Ketorolac, Pain Clinics Renal, Colic}
  • فاطمه فاموری *، طاهره ریاحی، محمدعلی زمانی، الهام هاشمی، کرمعلی کثیری
    زمینه و هدف
    کولیک شیرخواری یکی از شایع ترین مشکلات شیرخواران در 3 ماه اول زندگی است و حدود 28%-3% شیرخواران را درگیر می کند. این بیماری باعث نگرانی زیادی برای والدین و مشکلات درمانی برای متخصصین کودکان نیز می شود. پاتوژنز این بیماری هنوز ناشناخته است. هدف این مطالعه بررسی اثر پروبیوتیک لاکتوباسیلوس روتری (Lactobacillus reuteri) بر روی بهبود علائم و نشانه های کولیک شیرخواری در یک مطالعه آینده نگر بود.
    روش بررسی
    این مطالعه از نوع کار آزمایی بالینی مورد شاهدی است. تعداد 70 شیرخوار با معیارهای کولیک شیرخواری وارد مطالعه شدند و به صورت تصادفی در دو گروه دریافت پروبیوتیک لاکتوباسیلوس روتری (108 باکتری زنده روزانه) یا دایمتیکون (20 میلی گرم سه بار در روز) برای 28 روز قرار گرفتند.
    یافته ها
    70 شیرخوار 34 بیمار در گروه پروبیوتیک و 36 نفر در گروه دایمتیکون مورد بررسی قرار گرفتند. میانگین سنی گروه های پروبیوتیک و دیمتیکون به ترتیب 41/35 و 43/5 روز بوده است. میزان متوسط زمان گریه در دو گروه پروبیوتیک و دایمتیکون از میزان اولیه 206 دقیقه روزانه به 47±78/2 و 36/5±173/8 دقیقه روزانه به ترتیب بعد از دو هفته رسید. درنهایت 88% و 9% شیرخواران در گروه پروبیوتیک و دایمتیکون بهبود یافتند. عارضه جانبی برای هیچ کدام از دو دارو مشاهده نشد.
    نتیجه گیری
    داروی پروبیوتیک علائم و نشانه های کولیک را به صورت قابل توجه در شیرخواران شیر مادر خوار کاهش داد که می تواند بیانگر نقش مهم این دارو نه تنها در بهبود معیارهای کولیک بلکه در کاهش شدت دفع گاز شیرخواران که نشانه شدت نفخ شکم است، باشد.
    کلید واژگان: میکروب های دستگاه گوارش, پروبیوتیک, دایمتیکون, شیرخوار, کولیک}
    Fatemeh Famoori *, Tahereh Riahi, Mohammad Ali Zamani, Elham Hashemi, Karam Ali Kasiri
    Background And Aims
    Infantile colic is one of the most common problems within the first 3 months of life, which affects as many as 3% to 28% of newborn children. It causes appreciable distress for parents and pediatricians even though its pathogenesis remains unclear. The goal was to test the hypothesis that oral administration of probiotic (Lactobacillus reuteri) in a prospective randomized study was improved symptoms of infantile colic.
    Methods
    This is a case control clinical trial study. Seventy breastfed colicky infants were assigned randomly to receive either the probiotic L. reuteri (108 live bacteria per day) or dimethicone (20 mg/day) three times/day for 28 days.
    Results
    Seventy infants contain 34 and 36 in the probiotic L. reuteri and dimethicone groups, respectively. Average ages of L. reuteri and dimethicone groups were 41/35 and 43/5 days, respectively. Daily median crying times in the probiotic L. reuteri and dimethicone groups were reduced from initial value about 206 minutes/day on the seventh day to 65 and 141 minutes/day on the 28th day, respectively. Finally, 88% and 9% patients were improved in the probiotic L. reuteri and dimethicone groups, respectively. Furthermore, no adverse effects were reported.
    Conclusion
    The probiotic L. reuteri has improved colicky symptoms in breastfed infants within 2 weeks of treatment, which suggests that probiotics may have an important role in improving not only criteria of infantile colic but also severity of gas passing of them.
    Keywords: Gastrointestinal microbiome, Probiotics, Dimethicone, Infant, Colic}
  • Fatemeh Dorreh, Seyed Mojtaba Hashemi, Sajedeh Salehi, Majid Taheri, Amir Almasi-Hashiani
    Background
    Infantile colic imposes a heavy financial burden on families and the healthcare system. This study was conducted to evaluate the effect of Pedilact on the treatment of infantile colic.
    Materials And Methods
    In this randomized clinical trial, 84 infant younger than 3 months with infantile colic were divided in two groups of 42 cases each- probiotic and standard treatment. This study was done in Arak city, Iran between 2013 and 2016. The population of the study consisted of breastfed infants and formula-fed infants younger than 3 months (less than 13 weeks) who referred to Amir Kabir Hospital and pediatric clinics presenting crying and restlessness symptoms consistent with the modified Wessel criteria. In the treatment group, in addition to the main treatment, five drops of Pedilact (Iran) was daily administered for 28 days. In both groups, the main treatment was instructed to the parents and they were advised to do the following techniques to pacify the infant: making relaxing sounds or vocals, applying peaceful and rhythmic rocking motion, walking, and using mild tremor-like movements.
    Results
    In Pedilact and control groups, 54.75% and 28.57% of the cases were male, respectively. 23 infants (75.61%) in the Pedilact group and 33 infants (82.5%) in the control group were breastfed infants. The mean age of infants in Pedilact and control groups were 6.64 2.90 and 6.69 5.97, respectively.There was no significant difference between the Pedilact and control groups in terms of mean duration of crying time during a day (P= 0.075), and the number of crying attacks per day (P= 0.127), there was a significant decrease in both variables over time, but the mean for hours of sleep in the group receiving the standard treatment was significantly higher than that of the group receiving Pedilact (P= 0.001).
    Conclusion
    There was no significant difference between the control and Pedilact groups in terms of crying time during a day and the number of crying attacks. It should be mentioned that, in this study, sample size was relatively low; hence, a multicenter study is recommended.
    Keywords: Colic, Infant, Pedilact, Probiotics}
  • Fatemah Nahidi, Nafiseh Gazerani, Parsa Yousefi, Ali Reza Abadi
    Introduction
    Infantile colic is a painful condition in the first months of infancy. This study was carried out with the aim of testing the hypothesis that massage treatment has a clinically relevant effect on this condition.
    Materials And Methods
    This randomized clinical trial was conducted among 100 infants of
    Results
    Significant differences were not observed in infant and mother demographic information. Before intervention, the mean of total number, length, and severity of crying were 6.12 (1.76) time/day, 4.97 (1.37) hour/day, and 6.60 (1.54) in the massage group and 6.96 (2.9) time/day, 3 (1.31) hour/day, and 5.98 (2.22) in the rocking group, respectively. After 1 week of intervention, the mean difference of total number, length, and severity of crying were 4.08 (1.83) time/day, 2.81 (1.77) hour/day, and 2.9 (2.37) in the massage group and 0.56 (2.28) time/day, 0.27 (1.09) hour/day, and 0.02 (1.64) in the rocking group, respectively.
    Conclusions
    This trial of massage treatment for infantile colic showed statistically significant or clinically relevant effect in comparison with the rocking group.
    Keywords: Colic, infant, massage, rocking}
  • Ali Sheidaei, Alireza Abadi *, Farid Zayeri, Fatemeh Nahidi, Nafiseh Gazerani, Anita Mansouri
    Background
    Infantile colic, cry-fuss and sleep problems are transient in the initial months of life, but they contribute to maternal depression, parenting stress and family mental health problems. In this randomized clinical trial, we aimed to explore the efficacy of massage therapy compared to rocking in reducing infantile colic symptoms including duration and number of cries, sleep duration and severity of infant colic.
    Methods
    This was a single blind RCT study with a one-week follow-up. One hundred colicky infants aged younger than 12 weeks old were randomly assigned into massage and rocking groups. Infants in the massage group received a massage for 15-20 minutes once during a day and once at night before sleeping for a week. In the control group, mothers rocked their infants gently for 5-25 minutes when the symptoms of colic appeared. Parents recorded the details of the colic symptoms in a diary every day. A GEE approach was applied to explore the effect of the intervention.
    Results
    Efficiency of massage therapy was significantly higher than rocking. At the end of the study, the mean number of daily cries was 4.26±1.40 in the massage and 6.9±2.14 the rocking groups (p
    Conclusion
    Massaging significantly improved colic symptoms during a one-week intervention for all outcomes. In addition, significant differences were found between the intervention and control groups in favor of massaging. Therefore, massage therapy is more effective than rocking for treating infant colic symptoms.
    Keywords: Colic, Massage, Clinical Trial, Pediatrics}
  • علی شیدایی *، علیرضا ابدی، فاطمه ناهیدی، فرید زایری، نفیسه گازرانی
    سابقه و هدف
    کولیک شیرخواری و به تبع آن گریه، بی قراری و بی خوابی شیرخوار یک مشکل گذرا در ماه های نخست زندگی شیرخواران می باشد. این مشکل می تواند بر افسردگی مادران، استرس والدین و وضعیت سلامت روانی خانواده تاثیرگذار باشد. هدف این مطالعه، بررسی اثر ماساژ بر کاهش شدت گریه و افزایش مدت زمان خواب شیرخواران است.
    مواد و روش ها
    در این کارآزمایی بالینی، 100 شیرخوار به صورت تصادفی به دو گروه مداخله و کنترل تقسیم شدند. شیوه ی صحیح ماساژ به مادران گروه مداخله آموزش داده شد و از آنها خواسته شد در طول یک هفته، روزی سه بار ماساژ را برای شیرخوار انجام دهند. در گروه کنترل، مادران با استفاده از تکان دادن شیرخوار، علایم کولیک را برطرف می کردند. در هر گروه، والدین روزانه شدت گریه و مدت زمان خواب شیرخواران را در چک لیست مربوطه ثبت نمودند. در نهایت، از مدل حاشیه ای برای تحلیل داده ها استفاده شد.
    یافته ها
    در گروه ماساژ، برآورد میانگین شدت گریه در طول یک هفته، از 01/ 5 به 47/ 2 واحد کاهش یافت، درحالی که در گروه کنترل (تکان)، این میانگین از 27/ 4 به 78/ 3 تقلیل پیدا کرد. همچنین، تفاوت میانگین مدت زمان خواب شیرخواران از 81/ 1 ساعت به نفع گروه تکان، به 26/ 1 ساعت به نفع گروه ماساژ رسید. شدت گریه در شیرخواران مشارکت کننده در این کارآزمایی در ساعات شب و بعدازظهر، به طور معناداری بیشتر از ساعات صبح به دست آمد.
    نتیجه گیری
    ماساژ به عنوان یک درمان بی خطر در بهبود علایم کولیک شامل شدت گریه و مدت زمان خواب، موثر است.
    کلید واژگان: کولیک, ماساژ, کارآزمایی بالینی, شیرخواران}
    Ali Sheidaei *, Alireza Abadi, Fatemeh Nahidi, Farid Zayeri, Nafiseh Gazerani
    Background And Aim
    Infantile colic and sequence of cries, irritability and sleep problem are transient in the initial months of life. It could affect maternal depression, parent’s anxiety and family health situation. The aim of this study is to explore effect of massage on infantile cries severity and duration of sleep.
    Materials And Methods
    In this randomized clinical trial, one hundred infants assigned randomly into intervention and control groups. Correct method of massage for mothers in intervention group was taught and they were asked to massage infants three times a day for a week. In control group, mothers used rocking to relief colic symptoms. In both groups, Parents registered cries severity and sleep duration on diary. Finally, marginal model was used to analyze data.
    Results
    In the massage group, means of cries severity decrease from 5.01 to 2.47 in a week while in the control (rock) group this mean reduce from 4.27 to 3.78. In addition, mean difference of sleep duration between groups was 1.81 hours in favor of rock group at the first day of study. It became 1.26 hours in favor of massage group at the end of trial. Severity of cries among infants of this study in the afternoon and at night was significantly higher than in the morning.
    Conclusion
    Massage as a safe treatment can affect cries severity and sleep duration of infants.
    Keywords: Colic, Massage, Randomized clinical trial, Infant}
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