جستجوی مقالات مرتبط با کلیدواژه « h1n1 » در نشریات گروه « پزشکی »

Influenza is one of the most important viral diseases with high mortality and morbidity that can have a great impact on public health and economy.

To investigate the clinical and epidemiological features of influenza virus A/H1N1, A/H3N2, and B infection in Fars province, southern Iran, in 2015-2019.

In this retrospective cross-sectional study, we assessed the archived data of Syndromic Surveillance System of Iran’s Health Ministry, allowed access by Communicable Diseases’ Unit of Health chancellor of Shiraz University of Medical Sciences, from December 22, 2015 to September 22, 2019. The participants included all patients whose data were recorded as influenza-like illness (ILI) and severe acute respiratory infections/illness (SARI). Influenza viral infection was confirmed by reverse-transcriptase polymerase chain reaction (RT-PCR).

Totally, 1269 patients suspected of influenza were sampled. The mean ± SD of age was 29.40 ± 26.91 years. Fever was the most common symptom (68.6%). The highest incidence was in winter (55.9%). Of 928/1269 laboratory’s results which were recorded in the registry, 204 (16.08%) samples were positive and 724 (57.05%) were negative. Among 204 positive results, 191 (15.05%) were influenza type A, and 8 (0.63%) influenza type B. Among patients with definite influenza type A, 34 (2.68%) had H1N1/p subtype, 58 (4.57%) H3N2, and one (0.08%) had other subtypes; however, subtypes were not identified in 7.72% of patients. Six (3.0%) patients with confirmed influenza expired.

The incidence of influenza, especially type A, in Fars province, southern Iran is considerable and requires more attention for prevention in health policy programs.

Influenza viruses are classified into three types of A, B, and C, with H1N1 being a member of the influenza A subtype. The majority of people infected with influenza, namely H1N1, exhibit self-limited, uncomplicated, and acute febrile respiratory symptoms, or are asymptomatic. However, severe disease and complications due to infection, including hospitalization and death may occur. One of the most prominent features of influenza infections are radiologic findings in chest X-rays, computed tomographic scan, and angiographies.

In a descriptive-analytical study, all patients who were diagnosed with H1N1 at the Sina Educational-Medical Center of Tabriz University of Medical Sciences (Tabriz, Iran) from September 2015 to September 2016 were analyzed based on age, clinical presentation, and radiological findings.

A total of 53 cases, 30 females (57%) and 23 males (43%), were included in the study. The mean age was 48.45 ± 1.7. The most common clinical presentation was myalgia (92.5%). Chest X-ray (CXR) was done in all patients, 35 cases (66%) were found with bilateral abnormality, 11 cases (20.8%) without abnormality, and seven cases (13.2%) with unilateral abnormality. Chest computerized tomography (CT) scan was also done on all patients, 33 cases (62.2%) were found with bilateral abnormality, 17 cases (32%) without abnormality, and three cases (5.6%) with unilateral abnormality. CT angiography was done in eight patients; none of the patients showed any signs of pulmonary embolism. It was observed that CXR and CT-scan were both precise in studying radiological findings in H1N1.

The majority of patients had revealed bilateral abnormality in radiographic findings, and unilateral involvement was less common; in addition, involvement in the superior lobes of the lungs were more common than the basal lobes. CXR and CT scans had no significant difference in diagnosing the disease.

The recent outbreak of COVID-19 is considered to be one of the biggest disasters faced in the history which has already killed 211568 and effected 3065739 people across the world (As on 28th April 2020). Thus, there is an alarming need to discuss novel treatment strategies for treatment of such viral outbreaks. Viral diseases affect millions of people around the world, with a major effect on human health and socio-economic development. The human immunodeficiency virus (HIV) affects more than 40 million people alone. This analysis examines the different nanocarriers (e.g. liposomes, solid lipid nanoparticles, polymeric nanoparticles, etc.) based on methods implemented in the literature and in the clinic to address the numerous challenges faced by the antiviral therapy. This review includes recent strategy devised using Nanomedicine to treat H1N1 Influenza virus.  In this review we also tried to discuss few viruses which help in cancer therapy including recent developments in treatment of COVID-19 using Nanotechnology.

Influenza A/H1N1 pandemic has recently threatened the health of world’s population more than ever. Non-pharmaceutical measures are important to prevent the spread of influenza A/ H1N1 and to prevent a pandemic. Effective influenza pandemic management requires understanding of the factors influencing preventive behavioral. This study reports on predictors of students’ preventive behaviors for pandemic influenza A/H1N1 using variables based on the protection motivation theory (PMT).

In a cross-sectional study, multiple-stage randomized sampling was used to select 300 female students in Isfahan who completed a questionnaire in December 2009. Data were collected using a self-report questionnaire based on PMT. The statistical analysis of the data included bivariate correlations, Mann-Whitney, Kruskal-Wallis, and linear regression.

The mean age of participants was 15.62 (SE = 1.1) years old. Majority of participants were aware regarding pandemic influenza A/H1N1 (87.3%, 262 out of 300). Results showed that, protection motivation was highly significant relationship with preventive behavior and predicted 34% of its variance. We found all of the variables with the exception of perceived susceptibility, perceived severity, and response cost were related with protection motivation and explained 22% of its variance.

Promotion of students’ self-efficacy, and intention to protect themselves from a health threat should be priorities of any programs aimed at promoting preventive behaviors among students. It is also concluded that the protection motivation theory may be used in developing countries, like Iran, as a framework for prevention interventions in an attempt to improve the preventive behaviors of students.