جستجوی مقالات مرتبط با کلیدواژه "lung contusion" در نشریات گروه "پزشکی"

Due to its size, vascular structure, and fragile parenchyma, the liver is considered the most common cause of mortality due to abdominal solid organ injury. Here we present a case of a patient suffering from blunt liver trauma with a review of the literature.

A young 33 years old male patient was referred to our medical center by the EMS with a chief complaint of pain and dyspnea due to direct thoracoabdominal trauma. The patient presented with hypotension and was transferred to the intensive care unit for close monitoring. Radiologic investigations showed lung contusion with grade V liver injury. The patient underwent damage control surgery and the definitive surgery following that and showed no signs of complication during the hospital stay and follow-up visits.

Trauma is among the leading causes of death worldwide, with head and extremities being the most affected injury sites, followed by abdominal trauma. The most affected group is young males. During the last decades, non-operative management(NOM) of abdominal trauma has increasingly gained popularity among surgeons due to the prevention of laparotomy complications such as infections. Concomitant injuries, including solid and hollow organs alongside liver trauma, affect the morbidity and mortality status of the patient and are associated with high mortality rates if not addressed immediately and appropriately.

Pulmonary contusion (PC) is a clinical entity that often accompanies blunt traumas. We aimed to investigate the radiological and histopathological effects of surfactant treatment in an experimental rat model in which lung contusion was formed by blunt thoracic trauma. 50 female Sprague-Dawley rats were used. Five groups were formed randomly. In groups 2, 4, and 5 lung contusion was made by the drop-weight method after anesthesia. Intratracheal surfactant was administered in the 4th hr in groups 3 and 4 and in the 24th hr in groups 4 and 5. All rats were sacrificed and their lungs removed at 48 hr after contusion. Alveolar edema, congestion, hemorrhage, destruction, leukocyte infiltration, immune staining were examined histopathologically. When the first thoracic CT scans were evaluated, we observed two rats with rib fractures and four rats with pneumothorax. 4 and 48 hr thoracic CT evaluation contusion and atelectasis showed no statistically significant decrease (P>0.05). After sacrifice of group 2, in macroscopic evaluation, there was a heterogeneous contusion and hemorrhagic appearance in the lungs of rats and less hemorrhagic appearance was observed in Groups 4 and 5 than in Group 2. In comparison of Immunohistopathological findings, surfactant treatment showed a statistically significant decrease in leukocyte infiltration scores (P=0.046). Immunohistopathologically, surfactant group had more staining but only statistically significant when compared to groups 4 and sham. (P=0.036). Surfactant treatment may be of significant benefit in lung contusion secondary to blunt chest trauma, and further prospective evidence of its efficacy in such disorders is needed.