جستجوی مقالات مرتبط با کلیدواژه « myoma » در نشریات گروه « پزشکی »

Nowadays, the prevalence of uterine myoma in pregnant women has increased due to the increasing age of pregnancy in women.In this case report, a pregnant woman (window period) with a negative result of ßhCG test and ultrasound in terms of pregnancy underwent myomectomy surgery to remove a large uterine myoma. A 40-year-old patient referred to the physician because of heavy and prolonged menses caused by a large uterine myoma and primary infertility for 10 years. ßhCG test and ultrasound of the patient were negative in terms of pregnancy, and she underwent myomectomy surgery while the patient was in the early stages of pregnancy (window period). Therefore, the patient was under close care during pregnancy. With continuous follow-up, the newborn was born without any problems at 37 weeks. Although in this study, with proper management during surgery, and continuous and regular follow-ups, the newborn was born healthy, but confirmation of myomectomy during pregnancy requires the implementation of more studies.

 Aluminum (Al) is used in different industries to produce cosmetics, supplements, drugs, food packaging, toothpaste, kitchen utensils, and antiperspirants. Uterine fibroid (UF) is women's most prevalent benign tumor during the reproductive ages. Since Al can accumulate in the body's organs, it may play a role in the pathogenesis of UF. This study aimed to measure Al levels in serum and uterine samples (normal uterine tissue of control and UF patients, and leiomyoma of UF patients).

 In this descriptive study, we included ten women who underwent hysterectomy (five women due to UF and five women for a reason other than UF). Samples were obtained from serum, normal uterine tissue, and leiomyoma. Tissue and serum samples were digested with nitric acid (HNO3) and hydrogen peroxide (H2O2). Eventually, the Al levels in samples were analyzed by inductively coupled plasma atomic emission spectroscopy (ICP-AES).

 Al level was higher in the serum of the control group compared with UF patients (326.8 ± 360.8 µg/L vs. 211.2 ± 56.4 µg/L, P =0.310). Al level was higher in the control group compared with the normal tissue of UF patients (410.2 ± 244.7 µg/L vs. 300 ± 138.0 µg/L, P=0.465). Besides, leiomyoma had a higher Al level compared with the normal tissue of UF patients (1482.2 ± 2062.9 µg/L vs. 300 ± 138.0 µg/L, P=0.138).

The results showed that Al levels of tissue and serum samples in various groups differed, but these differences were not statistically significant.

 Although laparoscopic myomectomy is an effective procedure for the treatment of uterine myoma, there is no clear consensus regarding its rate of recurrence and associated risk factors.

 This study aimed to investigate the recurrence rate of myoma and its risk factors after laparoscopic myomectomy.

 In a historical cohort study, 172 patients who underwent laparoscopic myomectomy and had a minimum follow-up of 2 years were included. Myoma recurrence was checked semiannually by ultrasound imaging. The demographic, clinical, surgical, sonographic, and laboratory indices of the patients were compared between the recurrent and nonrecurrent groups, both in logistic regression models.

 The mean age of the patients was 35 ± 5.7 years (range: 18 - 47 years). Their mean follow-up time was 26.3 ± 4.2 months (range: 24 - 28). The lesion recurred in 25 (14.5%) out of 172 patients. In the univariate analysis, higher age (OR:1.111, P = 0.015), higher body mass index (OR: 1.124, P = 0.024), gonadotropin-releasing hormone (GnRH) therapy (OR = 3.83, P = 0.027), and more than 1 myoma (OR: 2.60, P = 0.032) were associated with myoma recurrence. In the multiple analysis, a higher body mass index (OR: 1.222, P = 0.003) was a significant risk factor for myoma recurrence.

 Laparoscopic myomectomy is an effective procedure for the treatment of uterine myoma and can be used as a uterus-preserving surgical alternative in patients of reproductive age. A more radical surgical procedure might be used for patients with multiple risk factors, as revealed in the present study.

We report a 33 years multipara pregnant woman who presented with vaginal bleeding due to intramural myoma and preeclampsia. After cesarean section, the myoma changed to the peduncle type and entered the internal space from the inner thickness of the uterus. This infrequent phenomenon made it easier to operate and remove the myoma within a few hours after the cesarean section. Finally, the mother and baby were discharged from the hospital safely after a few days.

Myoma is the most common benign monoclonal neoplasm of the uterus with increased frequency during reproductive years of women.

A twenty two year old female presented with abdomen lump, dysmenorrhoea, and heavy menstrual bleeding. Multiple myomas were diagnosed based on clinical and radiological findings. Abdominal myomectomy was performed and 75 myomas were enucleated followed by reconstruction of uterus. The second case was a 28 year old married woman presented with heavy menstrual bleeding and dysmenorrhoea. Ultrasound reported single posterior wall myoma of 86.35.8 cm in size. Laparoscopic myomectomy was performed. At follow-up visit, both cases were completely free of any symptoms.

Myomectomy is a feasible and safe option and a uterine preserving surgery even in the presence of multiple myomas. Setting appropriate criteria in selecting patients for abdominal myomectomy rather than MIS is essential to avoid conversion and associated morbidity.

Myomas are the most common non-malignant pelvic neoplasm in women’s reproductive life. The aim of present study was to compare the outcome of large myoma Laparoscopy in Iranian reproductive-age women.

This cross-sectional study was conducted on 86 women with symptomatic uterine myoma who underwent laparoscopic myomectomy between December 2013 and October 2018. Participants were divided into two groups based on the myoma weight (<80 (n=15) and ≥80 g (n=71)). Finally, age, body mass index, number of myomas removed, duration of surgery, postoperative hospitalization, amount of blood transfusion, and hemoglobin reduction were compared between the two groups. Data were analyzed by SPSS software version 22.

The mean age of participants were similar in both groups (P=0.48). There were no significant differences between the two groups regarding body mass index (P=0.56) and indications for laparoscopic myomectomy (P=0.46). The mean weight of myoma and duration of surgery were significantly different between the two groups (P<0.001 and P<0.007, respectively). Changes in hemoglobin and days of hospitalization after surgery were not significantly different between the two groups.

The length of hospital stay and blood loss in laparoscopic myomectomy did not differ significantly based on myoma weight. So, laparoscopic myomectomy could be considered a minimally invasive alternative for managing symptomatic large myoma.

Tricuspid valve myxomas are very uncommon tumors that could be found after the occurrence of pulmonary thromboembolism, symptomatic tricuspid obstruction, and right-sided heart failure.  Herein, we describe a 42-year-old woman evaluated for an abdominal mass. In preoperative consultation, a tricuspid valve mass was detected in echocardiography. She underwent the removal of a benign uterine myoma and a myxoma of the tricuspid valve. Tricuspid valve myxomas constitute a scarce diagnosis. They could be asymptomatic, occurring in unusual locations and in association with benign tumors in other organs. Our patient was asymptomatic, underscoring the significance of the early diagnosis of this type of tumor to prevent further catastrophic events.

Uterine fibroids (UF) in pregnancy is a condition, where symptomatic or asymptomatic fibroids in the uterine cavity may cause complications in pregnancies. Placental abruption and preterm labor, occurs in late pregnancy, postpartum hemorrhage, caesarean section and retained placenta in perinatal period. This study aimed to reckon whether the surgical Caesarean myomectomy is still a gold standard in myoma removal in pregnant women.

 This study was retrospectively conducted in pregnant women deliveries with uterine fibroids who underwent Myomectomy with lower segment caesarean section (LSCS). The caesarean myomectomy cases were compared with LSCS alone controls in 1:2 ratio. The primary outcome is to minimize blood loss and need for blood transfusion. The secondary outcome is the length of surgery duration and hospital stay.

The outcome of case and control compared was 43 caesarean myomectomy with LSCS as case group and 86 LSCS Alone as control group. The incidence of hemorrhage in case group was 10 out of 43 while control was 2 out of 86 (2.32%) with P-value of 0.0017. The secondary outcome was the length of surgery duration and hospital stay which were found statistically significant between the case and control groups, with P-value = 0.0001 and 0.0072, respectively.

 Caesarean Myomectomy can be the effective surgical option to enucleate uterine myoma, and preserve uterus and jettison from eventful or symptomatic uterine fibroids. To have the chances for prevention of immediate or interval - myomectomy / hysterectomy and control of post-partum menstrual over bleeding.

To investigate the impacts of myomas on the outcomes of pregnancy in Iranian pregnant women with uterine fibroids.

In this retrospective cohort study, the consequences of myomas on pregnancy were investigated in Iranian pregnant women referred to the perinatology clinic of Mahdieh Hospital (Tehran, Iran). One-hundred and sixty pregnant women diagnosed with uterine myoma were enrolled in the study as the case group. The control group consisted of 160 pregnant women without fibroma. The characteristics of the myomas and their relationships with pregnancy outcomes were surveyed.

Non-cephalic presentation, preterm labor, and Cesarean delivery were significantly higher in the case group in comparison with the control group. 106 patients (66.7%) had myomas larger than 5 cm in diameter. Intramural fibroids were seen in 132 (83%) patients. In addition, 133 (83.6%) patients had myomas in the body (corpus) of the uterus. Considering the number of myomas, 124 (78%) patients revealed one myoma in uterus. Uterine myomas during pregnancy rendered an important risk factor for cesarean delivery, breech presentation, and preterm delivery. However, there were no significant correlations between uterine myomas and IUGR, premature membranes rupture, either abortion or bleeding in the first trimester, low birth weight, and severe postpartum bleeding.

Our results showed that the presence of myoma could modulate pregnancy outcomes. Our results can be useful in improving the quality of prenatal care and education.

Inversion of the uterus is very uncommon. Patients may present withpelvic pain, vaginal discharge, or hemodynamic shock.

Case: 

We report a case of 35 years old women (virgin) who was admitted with profusevaginal bleeding and cramps of uterus. In the vaginal examination at litothomy positiona mass of 5×8 cm in size was protruded from the vagina. At first myomectomy wasperformed and after that laparotomy with total abdominal hysterectomy was done.

Early diagnosis, immediate treatment of shock, and replacement areessential in uterine inversion.