جستجوی مقالات مرتبط با کلیدواژه "premature ejaculation" در نشریات گروه "پزشکی"

 Men suffering from premature ejaculation often report emotional and relational problems, and some of them do not pursue sex due to embarrassment. This condition leads to mental disorders, e.g., anxiety and depression, and the couple's relationship may suffer.

 The present study aimed to investigate the effectiveness of transcranial direct-current stimulation (tDCS) and behavior therapy using the start-stop method in improving premature ejaculation.

 This was a quasi-experimental study with two experimental groups and a control group. The statistical population comprised all men with premature ejaculation residing in Tehran (2021) who visited sexual health centers in this city. A sample of 45 men aged 25-65 was selected using convenience sampling and divided into three groups of 15. The research instrument included the International Index of Erectile Function (IIEF). The data were analyzed in SPSS-23 using the analysis of covariance.

 The mean ± SD of the pretest of premature ejaculation in the tDCS, start-stop method, and control groups was 13.60 ± 5.45, 12.86 ± 3.24, and 15.68 ± 4.87, respectively; while in the posttest was 23.53 ± 9.65, 18.66 ± 5.25 and 17.53 ± 4.83, respectively. Based on the results, tDCS alleviated premature ejaculation (P < 0.001). The start-stop method also decreased the symptoms of premature ejaculation, but this reduction was not significant. There was a significant difference between the two treatment methods, and tDCS proved more effective.

 tDCS demonstrated acceptable effectiveness in the treatment of premature ejaculation. Given its effectiveness in increasing marital satisfaction, it should be considered in the treatment of premature ejaculation.

Premature ejaculation (PE) is acommonsexual dysfunction in men, affecting various aspects of life, including mental and emotional health and interpersonal relationships with spouses.

The present study aimed to investigate the effects of transcranial direct current stimulation (tDCS) on the treatment of PE in men with sexual dysfunction.

This was a quasi-experimental study with a pretest-posttest control design and a two-month follow-up. The statistical population included all men with PE living in Tehran, Iran, in 2021. A total of 30 people within the 25 - 66 age group were selected and placed in the experimental and control groups. The experimental group underwent tDCS for one month (8 sessions), and the control group received no intervention. The research instrument included the international index of erectile function (IIEF). The data were analyzed using descriptive and inferential statistics (ANCOVA) with SPSS.

The experimental and control groups had a significant difference in the components of PE, including orgasmic function and overall satisfaction (P < 0.001). The results suggested that tDCS improved orgasmic function and overall satisfaction in men with sexual dysfunction. Furthermore, this method remained effective for two months.

The tDCS method was influential in improving PE. Considering the effectiveness of tDCS in treating PE and increasing sexual satisfaction, it is recommended to use this method to treat this disorder.

Premature ejaculation (PE) is a common sexual dysfunction in men, affecting various aspects of life, including mental and emotional health and interpersonal relationships with spouses.

The present study aimed to investigate the effects of transcranial direct current stimulation (tDCS) on the treatment of PE in men with sexual dysfunction.

This was a quasi-experimental study with a pretest-posttest control design and a two-month follow-up. The statistical population included all men with PE living in Tehran, Iran, in 2021. A total of 30 people within the 25 - 66 age group were selected and placed in the experimental and control groups. The experimental group underwent tDCS for one month (8 sessions), and the control group received no intervention. The research instrument included the international index of erectile function (IIEF). The data were analyzed using descriptive and inferential statistics (ANCOVA) with SPSS.

The experimental and control groups had a significant difference in the components of PE, including orgasmic function and overall satisfaction (P < 0.001). The results suggested that tDCS improved orgasmic function and overall satisfaction in men with sexual dysfunction. Furthermore, this method remained effective for two months.

The tDCS method was influential in improving PE. Considering the effectiveness of tDCS in treating PE and increasing sexual satisfaction, it is recommended to use this method to treat this disorder.

Alcohol is a potent substance that causes both acute and chronic changes in almost all neurochemical systems, with the result that heavy drinking can produce serious psychological symptoms including depression, anxiety, and psychoses. It alsoaffects sexual health adversely and causes sexual dysfunction.

This study aimed to find the prevalence and pattern of sexual dysfunction in male patients with alcohol dependence. This cross-sectional study included 100 patients attending psychiatry out patient department (OPD) at a tertiary care center in west India. Informed written consent was taken for collecting socio-demographic and clinical data in a uniform and standard manner. Sexual dysfunction was assessed using a sexual dysfunction checklist, constructed by Arackal and Benegal at the national institute of mental health and neuroscience, Bangalore containing 12 items from the diagnostic criteria for research and ICD-10 classification of mental and behavioral disorders. The Leeds dependence questionnaire was used to assess the severity of alcohol dependence. 

Sexual dysfunction was present in 62% of the patients. Among the patients, 36% had difficulty achieving an erection, 34% had difficulty maintaining an erection, 37% reported premature ejaculation, 7% had delayed ejaculation, 14% reported anorgasmia, 1% had ejaculation with a flaccid penis, 2% had pain during intercourse, 6% were dissatisfied with the frequency ofintercourse, 4% were dissatisfied with their sexual partner, and 7% were dissatisfied with their performance. 

Sexual dysfunction is significantly and positively associated with duration, amount of alcohol consumed per day, and severity of alcohol dependence.

The purpose of this study was to compare the effectiveness of Dapoxetine, and Paroxetine as well as Dapoxetine/Tadalafil and Paroxetine/Tadalafil combinational therapies, for the treatment of patients with prema-ture ejaculation.

In this clinical trial study, 120 patients with premature ejaculation were randomly divided into 4 groups: The first group was treated with Paroxetine (Pa), while the second group received Dapoxetine(Da). The third group received Paroxetine combined with Tadalafil(PT) whereas the fourth group's treatment involved the use of Dapoxetine and Tadalafil(DT) for one month. In the next 2 and 4 weeks, the cases were evaluated in terms of ejaculation duration, frequency of intercourse per week, and drug side effects.

The mean age of the Da, Pa, PT, DT groups was 32 ± 6.9, 32.4 ± 7.2, 31.6 ± 1.9, and 32.9 ± 7.7 years, respectively. There was a significant difference between the Da and DT groups (p = .029) in the ejaculation latency in the 4-week follow-up. In the two weeks follow-up, a significant difference was observed between DA and DT (p = 0.043), Pa and PT (p = 0.006), and Pa and DT groups (p = 0.004) in terms of ejaculation latency. Four weeks after the intervention, a significant difference was detected in the intercourse frequency of Da and PT groups (p =0.033), Pa and PT groups (p = 0.043), Pa and DT groups (p = 0.02), and Da and DT groups (p = 0.016).

Combination therapy (Tadalafil plus Paroxetine or Dapoxetine) was more effective in IELT (Intra ejaculation latency time) than mono-therapy especially in younger patients despite its slightly more side effects.

Premature ejaculation is one of the most common sexual disorders worldwide without a satisfying treatment. In this study, we investigated the efficacy of a topical formulation of clove oil in premature ejaculation patients. Eligible patients were randomly divided into two groups to use either Syzygium aromaticum (SA) 1% gel or placebo gel 10 minutes before the intercourse for a period of 8 weeks. Outcome measurement were Premature Ejaculation Diagnostic Tool (PEDT) and International Index of Erectile Function (IIEF) questionnaires in addition to Intravaginal Ejaculation Latency Time (IELT). A total number of 22 (11 patients in each group) participants completed the study. At the end of the intervention, the IELT scores changed from 29.84 ± 18.59 to 97.09 ± 91.86 and 42.51 ± 13.98 to 52.45 ± 32.7 seconds in SA gel and placebo groups, respectively (p-value = 0.003). Also, the changes of PEDT scores in the SA gel group (from 14 ± 3.55 to 9.2 ± 4.56) comparing to that of placebo gel group (from 14.63 ± 3.61 to 13.5 ± 3.78) was significantly different (p-value =0.001). Moreover, results of IIEF questionnaire revealed significant improvement of “Intercourse Satisfaction” in SA gel group (p-value = 0.016). No adverse event was observed. It seems that SA gel could be beneficial in the treatment of premature ejaculation; however, it should be further evaluated in larger studies.

Premature ejaculation (PE) is the most common male sexual dysfunction. Although its etiology isnot fully understood, several organic and psychological disorders have been identified as risk factors. The mainaim of this study is to find any association between religious orientation (RO) and PE.

We designeda cross-sectional study and 80 participants with PE as the main chief complaint were enrolled. After filling in-formed consent, all participants have filled two questionnaires including the Premature Ejaculation DiagnosticTool (PEDT) for PE and the Allport & Ross intrinsic-Extrinsic Religious Orientation Scale for RO assessment re-spectively. Spearman’s rho analysis was used for assessing the association between PEDT scores and ROS scoresby SPSS 22.0 version.

Out of 80 patients with mean age 35.56±8.46 years, 70 patients (87.5%) had PEDTpositive score. Of them, 45 (64%) had lifelong PE and 25 (36%) experienced an acquired PE. Correlation analy-sis was shown a reverse correlation between PEDT positive scores and Intrinsic RO (P = 0.05) with a correlationcoefficient -0.311, PEDT positive and negative scores was not correlated with extrinsic RO (P= 1).

Patients with a lower intrinsic religious orientation score have a higher probability for PE and PEDT positivescore.

Premature ejaculation (PE; early ejaculation or rapid ejaculation) is a common sexual problem affecting about 20-30% of men in the sexually active age group. PE can be of four types: Primary, secondary, natural variable, and subjective PE. Various non-pharmacological and pharmacological treatment options are available to treat PE including Dapoxetine, which is specifically developed for the treatment of PE. In this review, we discuss the pathophysiology and management aspects of PE.

To review in literature about the concept of premature ejaculation from physiology to treatment.

A literature search conducted with Pubmed and Cochrane.

An accurate clinical history is the best diagnostic method, and in the majority of the cases it is enough to differentiate between primary and acquired premature ejaculation. Nowadays the treatment is not curative but is effective in increasing the Intravaginal Ejaculatory Latency Time, improving the couple’s sexual satisfaction.

Although PE is the most frequent sexual dysfunction, it is still sub-diagnosed. Combining behavioural techniques with pharmacotherapy is the best way of treatment.

Premature ejaculation (PE) is one of the main sexual problems among the male population. There is a folk treatment for this ailment in a small town near Kashan, Iran. The treatment contains hydro-alcoholic extracts of Tribulus terrestris L., Rosa × damascena Herrm, Zingiber officinale Roscoe, and Crocus sativus L. in honey. The aim of this preliminary study was to evaluate the effect of the syrup on premature ejaculation. The study population was 17 outpatients visited by a traditional healer. Each patient was diagnosed clinically based on the Premature Ejaculation Diagnostic Tool (PEDT). Inclusion criteria included male participants between 20 to 60 years old, PE more than 6 months, PEDT score more than 11, IELT more than 1 minute, no severe organic disease. Exclusion criteria included taking any chemical drug during the intervention, and sexual contacts less than twice in 3 weeks. 17 male patients aged between 26-65 years old were eligible for the study according to the inclusion criteria. The patients enrolled in the study, filled out the written consent form and conditions of the research were explained. The medication (Bastibaj syrup) was administered for the patients 5 milliliters 3 times daily for 3 sequential weeks. The intravaginal ejaculatory latency time was recorded in all coitus. After the course of the intervention, the mean of IELTs before and after the intervention was compared via paired T-test. Results show that the mean IELT before the intervention (33.2 seconds) in comparison to after it (129.3 seconds) has been improved significantly (P<0.01). According to the results, the study revealed that the traditional remedy prescribed in this study, i.e. Bastibaj, can be effective in patients with premature ejaculation, and can prolong the IELT significantly

Premature ejaculation (PE) is a prevalent disorder in males leading to sequelae such as lack of self-confidence, anxiety, depression and unsatisfactory intercourse for these men and their partners. The aim of this study was to evaluate the relationship between ejaculation and physical activity. Group 1 comprised 112 participants who took regular physical activity and Group 2 comprised 126 participants with a sedentary lifestyle. The participants were 18-45 years old, same ethnic origin, insame location and had regular sexual activity for at least 6 months. A comparison was made by metabolic equivalents (MET), premature ejaculation diagnostic tool (PEDT) and intravaginal ejaculatory latency time (IELT). The mean age of Groups 1 and 2 was 25.34 years (range, 18-41 years) and 28.49 years (range, 19-45 years), respectively (P = .21). The mean PEDT score was 6.18 in Group 1, and 10.02 in Group 2. Significant differences were found between Groups 1 and 2 (P = .001). The mean MET score of Group 1 was 3448.23 METmin/week (3012-4496 MET- min/week) while the MET score of Group 2 was 201.87 MET- min/week (66-744 MET- min/week) (P = .001). The mean IELT of Groups 1 and 2 were 316.42 s (120-1530 s) and 189.32 s (20-450 s), respectively. The mean IELT was significantly higher in Group 1 (P = .001). The study results demonstrated that PE was less frequent in men that perform regular physical activity compared to those with a sedentary lifestyle. It can be assumed that regular physical activity may be effectual in gaining a sexual life of higher quality. Prospective studies with longitudinal data are needed to further understand the potential relationship between regular physical activity and premature ejaculation.

This randomized clinical trial was aimed to evaluate the effect of oral use of tamarind seed powder as an herbal product in patients affected by premature ejaculation (PE).

In this study, 75 patients randomized in tamarind group (25 patients received daily 130 mg tamarind seed powder), paroxetine group (25 patients received daily 20 mg paroxetine), and placebo group (25 patients). Patients received the treatment regimen for 4 weeks. The primary outcome was intravaginal ejaculatory latency time (IELT). The secondary outcomes were PE diagnostic tool score, sexual function using International Index of Erectile Function (IIEF), and complications. Studied sexual functions include erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction.

The mean of IELT in tamarind, paroxetine, and placebo groups at baseline was 35.2 ± 26.5, 38 ± 27.6, and 44 ± 34.9 s and at the end of study was 49.5 ± 48.2, 147.4 ± 209.6, and 46.9 ± 37.6 s, respectively, which in paroxetine group signifi cantly increased compared to other groups. IIEF scores for orgasmic function and intercourse satisfaction for paroxetine after treatment signifi cantly increased than that of other groups. The differences between tamarind and placebo groups for studied variables were not statistically signifi cant. The mean of increases in IELT for tamarind, paroxetine, and placebo groups was 14.35 ± 34.3, 109.4 ± 213.4, and 2.9 ± 9.3 s, respectively, which in paroxetine group was signifi cantly higher than other groups and in tamarind group was signifi cantly higher than placebo.

Paroxetine was signifi cantly better than tamarind seed powder and placebo although side effect in paroxetine was more frequent. IELT signifi cantly more increased in tamarind group compared to placebo.

Several medical therapies have been proposed for the treatment of premature ejaculation (PE). Paroxetine and tramadol were both reported to be effective in treatment of PE. In this study, the therapeutic effects of tramadol, paroxetine and placebo were compared in treatment of primary PE.
In this randomized, double-blind, placebo-controlled clinical trial, 150 patients were divided into 3 groups. One group was treated with tramadol 50 mg on- demand, the other group took paroxetine 20 mg on-demand and the third group was treated with placebo. Before starting treatment and after 12 weeks, patients were asked to measure their average intravaginal ejaculation latency time (IELT) and fill the PEP (Premature Ejaculation Profile) questionnaire.
At the end of the 12th week, the mean IELT and average of PEP scores improved in all 3 groups. The increase in tramadol group was significantly higher than the paroxetine and placebo groups (p The results showed that despite an increase in mean IELT and PEP scores in all 3 groups, the rate of improvement in tramadol group was significantly more than the others. Thus, tramadol may be considered as an appropriate alternative therapeutic option for lifelong PE.

Sexual dysfunction, specifically erectile dysfunction (ED), premature ejaculation (PE), and delayed ejaculation (DE), are debilitating diseases, especially in young men. The past decade has seen an increase in the number of young men (under 40 years of age) presenting to their physician with sexual dysfunction. Traditionally, sexual dysfunction in young men was viewed as a strictly psychosomatic problem stemming from underlying psychogenic causes such as anxiety or insecurity. While this is true in some cases, the advent of new diagnostic tools and pharmacotherapy have revealed that the prevalence of organic causes for these diseases is much higher than previously thought. In reality, many patients present with primarily organic sexual dysfunction that then triggers concomitant psychogenic stressors such as anxiety and depression which exacerbate their problem. This review focuses on the common etiologies of sexual dysfunction experienced by young men in order to help educate clinicians so that they may better understand, identify, and serve this growing patient population.