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عضویت

جستجوی مقالات مرتبط با کلیدواژه « sodium » در نشریات گروه « پزشکی »

  • Fatemeh Shirani, Seyedeh Mahsa Khodaei, Mojtba Akbari, Razieh Eshaghi, Mansour Siavash, Zahra Esfandiari*
    Background

     Regarding the importance of the prevention of non-communicable diseases (NCDs) and higher consumption of salt among the Iranian population than the level recommended by the World Health Organization, the aim of this study was to evaluate the accuracy of the salt mentioned in the traffic light labelling of nuts and seeds.

    Study Design:

     A cross-sectional study.

    Methods

     A total of 53 packaged nuts and seeds, including 7, 8, 9, 9, 10, and 10 samples of pumpkin, pistachios, almond, sunflower, peanut, and watermelon nuts and seeds, respectively, with traffic light labelling, were randomly purchased from several local markets in Isfahan, Iran. The amount of sodium was measured by the inductively coupled plasma-optical emission spectroscopy technique and then multiplied by 2.5 to achieve the amount of salt.

    Results

     Varying levels of traffic light labeling value accuracy were observed in most of the samples. In the almond, pistachio, peanut, and watermelon groups, the average amount of laboratory value had a statistically significant difference with the label value (P<0.05).

    Conclusion

     The results demonstrated that the salt content of 82% of the studied samples had discrepancies with the values stated on the traffic light labelling. The presentation of an accurate amount of salt content is essential for promoting healthy eating habits and enabling individuals to make informed choices about their diet. It is recommended that regulatory authorities should review labelling guidelines and enforce stricter compliance to ensure accurate representation of salt content on packaged foods.

    Keywords: Sodium, Salt, Nuts, Seeds, Traffic Light, Food Labelling, Iran}
  • Beraat Dener, Mustafa Fevzi Karagöz*, Hilal Betül Altintaş Başar, İbrahim Hakkı Çağıran, Saniye Bilici, Eda Köksal

    Hospital menus are profoundly important to meet the nourishment needs of patients. So, this study is conducted to determine the nutrient adequacy of adult patients’ normal diet menus.

    Methods

    An evaluation of 30-day fixed menus consisting of 4 dishes was conducted in four different public hospitals in Ankara, the capital of Türkiye. Mean adequacy ratio (MAR) and nutrient adequacy ratio (NAR) were used to examine the sufficiency of nutrients and meals.

    Results

    For all the hospitals, MAR value was found higher than %85. However, nutrient adequacy ratio of dietary fiber, calcium and magnesium were lower than the other nutrients.  It was determined that total fat, saturated fat, salt and cholesterol (except hospital D) contents were high according to the recommended values. Nevertheless, these fixed menus supplied 75% daily fiber on average. Hospital A and D menus met calcium requirements by 73% and 67%, respectively. While hospital D menus met magnesium (76%) and potassium (67%) requirements moderately, other hospitals approached 100% sufficiency for potassium. It is remarkable that in all the hospitals the amount of fruits seemed very low, up to 34%.

    Conclusion

    As the hospital meal is an essential part of in-patients’ institutional care and nutritional support, the nutrient contents of menus should be monitored for nutritional requirements and, if necessary, there should be initiatives and arrangements in standard recipes to reduce salt and fat contents.

    Keywords: Menu Planning, Nutritional Requirements, Fats, Sodium}
  • جان محمد ملک زاده، عزیزالله پورمحمودی*، فاطمه محمدی نیا
    زمینه و هدف

    رژیم غذایی ناسالم به عنوان یکی از عوامل خطر اصلی بیماری های غیرواگیر و باعث اکثر بیماری های مزمن و مرگ و میر ناشی از آنهاست که مستقل از سن، جنس و شرایط فرهنگی اجتماعی بر سلامت افراد تاثیرگذار است. شاخص تغذیه سالم یکی از روش های تدوین شده برای ارزیابی وضعیت رژیم غذایی و پیش بینی شانس بروز بیماری های مزمن است، باتوجه به این که تاکنون درباره کیفیت غذایی ساکنان شهر یاسوج تاکنون مطالعه ای انجام نشده بود، در این مطالعه وضعیت شاخص تغذیه سالم، دریافت چربی، کلسترول و سدیم در ساکنان بالای 19 سال شهر  یاسوج بررسی شد.

    روش بررسی

    این یک مطالعه  توصیفی می باشد که در سال 1398 بر 300 نفر از ساکنان شهر یاسوج با مراجعه به منازل نمونه گیری شده به صورت تصادفی انجام شد. ابزار جمع آوری غذای دریافتی استفاده از پرسشنامه بسامد خوراک 168 سیوالی بود، که به وسیله محققین پیشین تدوین و مورد استفاده قرار گرفته بود. شاخص تغذیه سالم با استفاده از امتیازبندی این شاخص در ابزارشاخص تغذیه سالم 1995 محاسبه و گزارش گردید. داده های جمع آوری شده با استفاده از آزمون کای دو تجزیه و تحلیل شدند.

    یافته ها

    بررسی وضعبت شاخص تغذیه سالم محاسبه شده بر اساس الگوی دریافت غذایی نشان داد که در 7/82 درصد (248 نفر) موارد شاخص کلی تغذیه افراد مطلوب و در 3/17 درصد (52نفر) نیازمند تغییر و اصلاح بوده است، در حالی که هیچ کدام از افراد مورد بررسی شاخص تغذیه ضعیف نداشته اند. در مجموع با حدود اطمینان 95 درصد 13 تا 22 درصد افراد مورد بررسی شاخص تغذیه نیازمند اصلاح داشته اند، هم چنین 9/78 درصد کلسترول دریافتی روزانه بالای 300 میلی گرم و 7/15 درصد سدیم دریافتی بالای 2300 میلی گرم و 3/29 درصد چربی بالای 30 درصد دریافت کرده بودند. بین وضعیت شاخص های اقتصادی اجتماعی مانند؛ سواد، شغل و مالکیت منزل با شاخص تغذیه سالم ارتباط معنی داری به دست نیامد.

    نتیجه گیری

    بر اساس اطلاعات به دست آمده، وضعیت دریافت کلسترول و سدیم در ساکنان شهر یاسوج بالا و دریافت کالری و وضعیت شاخص تغذیه در بخشی از افراد مورد بررسی نامطلوب بوده است که ضرورت توجه به وضعیت تغذیه، دریافت کالری و دریافت کلسترول و سدیم، که عامل خطر بیماری های قلب و عروق می باشند، وجود دارد.

    کلید واژگان: شاخص تغذیه سالم, بزرگسال, کلسترول, سدیم, چربی, کالری}
    JM .Malekzadeh, A.Pourmahmoudi*, F. Mohammadi Nia
    Background & aim

    Unhealthy diet - as one of the main risk factors of non-communicable diseases and responsible for most chronic diseases and their mortality, which affects people's health regardless of age, gender and social cultural conditions. The healthy eating index is one of the developed methods to evaluate the diet status and predict the chance of chronic diseases, considering the fact that no study had been done on the food quality of the residents of Yasuj, Iran. In the present study the status of the healthy eating index, fat intake, Cholesterol and sodium were investigated in residents over 19 years of age in Yasuj, Iran, in 2020.

    Methods

    The present descriptive study was conducted in 2020 on 300 residents of Yasuj randomly sampled at their houses. The food intake collection tool was the food frequency questionnaire with 168 questions, which was developed and used by previous researchers. The healthy eating index was calculated and reported using the scoring of this index in the 1995 healthy eating index tool. The collected data were analyzed using chi-square test.

    Results

    Examining the status of the healthy nutrition index calculated based on the pattern of food intake indicated that in 82.7% (248 people) cases, the overall nutrition index of people was favorable and in 17.3% (52 people) it needed to be changed and modified, while that none of the examined people had a poor nutrition index. In total, with a 95% confidence level, 13-22% of the people examined have nutritional index that needs correction, also 78.9% of daily cholesterol intake is above 300 mg, 15.7% of sodium intake is above 2300 mg, and 29.3% of fat is above 30%. had received between the status of socio-economic indicators such as; Literacy, occupation and home ownership did not have a significant relationship with the healthy eating index.

    Conclusion

    Based on the obtained information, the status of cholesterol and sodium intake in the residents of Yasuj, as well as the intake of calories and the status of the nutrition index in some of the surveyed people, was unfavorable, which is the need to pay attention to the nutritional status, calorie intake and cholesterol intake. and sodium, which cause the risk of cardiovascular diseases.

    Keywords: Healthy nutrition index, Adult, Cholesterol, Sodium, Fat, Calories}
  • Alireza Rajolani, Arezoo Alaee, Mohsen Nafar, Mohammad-Javad Kharazi-Fard, Kimia Ghods *
    Background

     End-Stage Renal Disease (ESRD) is a severe nephrological condition that can lead to permanent kidney damage. Therefore, early disease diagnosis is key to preventing casualties. The gold standard method of diagnosis tends to evaluate changes in sodium, potassium, calcium, phosphorus, urea, creatinine, and parathormone hormones in blood after dialysis. However, serum evaluation is not always possible or easy for patients. Therefore, saliva evaluation has been proposed in recent years as an alternative.

    Objectives

     The current article aims to evaluate metabolite in the saliva of ESRD patients.

    Methods

     In this descriptive-analytical study, 29 ESRD patients undergoing hemodialysis treatment were selected. Their saliva and serum samples were taken. The number of biochemical factors, including sodium, potassium, calcium, phosphorus, urea, creatinine, and parathormone hormone, was measured with an autoanalyzer device and related kits. Finally, the correlation of parameters in serum and saliva was examined using the Pearson test.

    Results

     The results showed a significant positive relationship between the levels of sodium, urea, and creatinine in serum and saliva samples (P < 0.05). On the other hand, there was no significant relationship between the serum and saliva levels of potassium, calcium, phosphorus, and PTH (P > 0.05).

    Conclusions

     Due to the significant correlation between some prominent biochemical factors in saliva and serum after hemodialysis in ESRD patients, saliva could be considered a non-invasive diagnostic fluid for monitoring kidney disease in the future.

    Keywords: End Stage Renal Disease, Hemodialysis, Sodium, Calcium, Potassium, Phosphorus, Urea, Creatinine, Parathyroid Hormone, Saliva}
  • Salman Nikfarjam, Elham Ramezanzade, Yasaman Borghei, Bahare Gholami Chaboki, Baharak Alizadeh, Samaneh Karami, Arsalan Salari, Seyedeh Fatemeh Mirrazeghi *
    Background

    Acute myocardial infarction (AMI) is one of the leading causes of death worldwide. Contradictory findings are available regarding the effects of changes in electrolytes in patients with an AMI.

    Objectives

    We aimed to investigate the effect of electrolyte changes on the 3-month outcome.

    Methods

    A total of 168 patients with AMI managed at Dr. Heshmat Hospital in Rasht, Iran, were investigated in this prospective cohort study by a census method. AMI was confirmed by biochemical, electrocardiographic, or angiographic evidence. Electrolyte serum levels, demographic characteristics, myocardial infarction type, ejection fraction (EF), and underlying diseases were collected in a checklist in the early hours after each patient entered the hospital. Information about patients’ outcomes and echocardiographic data were collected after three months. All data were analyzed using SPSS software version 22.

    Results

    Out of 162 patients with AMI, most (44%) were aged between 50 to 59 years, and 76.8% were men. In all models, the odds of non-recovery remained constant with increasing electrolytes. On uni-variable and multi-variable models, sodium showed a significant positive association with initial EF (unstandardized coefficient = 0.8 in both uni-variable and multi-variable models, approximately), and phosphorus displayed a significant negative association with initial EF (unstandardized coefficient = -4.5 in both uni-variable and multi-variable models, approximately). There was no significant association of electrolytes with follow-up EF in all models.

    Conclusions

    In this study, the phosphorus and sodium serum levels were significantly related to the initial EF. However, none of the studied electrolytes impacted the 3-month outcome in AMI patients.

    Keywords: Acute Myocardial Infarction, Electrolytes, Sodium, Potassium, Magnesium, Phosphorus}
  • Abdulrahman Hamza, Abubakar Mohammad Gumi, Aminu Umar Imam, Yusuf Sarkingobir, Umar Tambari, Mustapha Sahabi, Aliyu Sulaiman

    The objective of this study is to determine the effect of mango leaves in preserving the varied concentrations of metals (sodium, potassium, calcium, magnesium, and phosphorus) present in two tomato varieties in Sokoto, Nigeria. After the application of different mango leaves extracts in the postharvest preservation of Daneka tomato fruits in a randomized control design, and atomic absorption spectrophotometry of macro elements; the most elevated concentrations noticed significant difference at (p<0.05) were revealed in potassium (1.20±0.002 to 3.00±0.001 ppm), and calcium (1.27±0.003 to 2.15±0.002 ppm). The lower levels of metals noticed upon storage under mango leaves are revealed by phosphorus (1.10±0.002 to1.37±0.002 ppm), and sodium (0.90±0.001 to 1.30±0.001 ppm); and the least was revealed by magnesium (0.61±0.001 to 0.86±0.001 ppm). The different concentrations of elements upon addition of mango leaves in the postharvest preservation of UTC tomatoes in Sokoto, Nigeria show, the elevated concentrations revealed by phosphorus (2.5±0.001 to 3.8±0.004 ppm), potassium (2.00±0.001 to 2.99±0.001 ppm), and magnesium (1.01±0.001 to 2.59±0.001 ppm). The lower concentrations were observed in calcium (1.34±0.001 to 1.70±0.001 ppm), and sodium (0.55±0.005 to 1.80±0.002 ppm). The mango leaves possessed potential to preserve the Na, K, Ca, Mg, and P levels in tomatoes; thus could serve as cheap, accessible, and sustainable preservative in the state when improved.

    Keywords: Tomato, Macroelements, Minerals, Mango leaves, Sodium, Potassium, Calcium, Phosphorus, Diseases}
  • Khadijeh Yazdi, Sara Saadatmand, Einollah Mollai, Maliheh Abbasi, Majid Dastorani, Saeid Amirkhanlou
    Introduction

    Despite great advances in hemodialysis, complications during dialysis remain in force. Accurate assessment of dry weight is a determining factor in the prevention of hemodialysis complications. This study is designed to evaluate the effect of adjustment of ultrafiltration rate, on hemodialysis complications, based on dry weight calculation, by measuring the pre-dialysis serum sodium.

    Methods

      In this single-blind clinical trial 50 patients were included. The patients were randomly divided into case and control groups. First, in the intervention group, the blood sodium level was measured before dialysis. Then, the dry weight of the patients was determined, ultrafiltration was adjusted according to the dry weight, and the patients’ dialysis program was performed. In the control group, dry weight was determined routinely. Blood pressure, muscle cramps, nausea, and vomiting were recorded in both groups for 3 months.

    Results

    The results showed a significant difference between the two groups in the rate of postoperative nausea and vomiting (P < .05) and muscle cramps during dialysis (P < .05). There were no significant differences between the two groups in blood pressure drop during dialysis and fatigue after hemodialysis in the first, second, and third months (P > .05).

    Conclusion

      Accurate assessment of dry weight by the pre-dialysis blood sodium formula, reduces muscle cramps, nausea, and, vomiting.

    Keywords: kidney disease, hemodialysis, dry weight, sodium}
  • Nargeskhatoon Shoaibinobarian, Leila Danehchin, Maedeh Mozafarinia, Azita Hekmatdoost, Sareh Eghtesad, Sahar Masoudi, Zahra Mohammadi, Ali Mard, Yousef Paridar, Farhad Abolnezhadian, Reza Malihi, Zahra Rahimi, Bahman Cheraghian, Mohammad Mahdi Mir‑Nasseri, Ali Akbar Shayesteh *, Hossein Poustchi
    Background

    The dietary approaches to stop hypertension (DASH) encourages high fruit, vegetable, and lean protein consumption and low salt, red meat, and fat intake to prevent or treat hypertension. However, besides hypertension, adherence to this diet has been shown to decrease other cardiovascular risk factors.

    Methods

    This study assessed the relationship between the DASH diet and cardiovascular risk factors in a cross‑sectional study of 2,831 adults chosen by multistage cluster sampling from 27 counties of Khuzestan province, Iran. DASH scores were calculated using data obtained from a qualitative food frequency questionnaire. Regression models were used to evaluate the association of DASH scores and common cardiovascular risk factors.

    Results

    Significant trends were observed across quintiles of DASH scores for systolic blood pressure, fasting blood sugar, triglyceride, total cholesterol, and its components (p < 0·05). After adjusting for potential confounders such as sex, age, ethnicity, residence, wealth score, physical activity, energy intake, and family history of heart disease, the multiple regression analysis for each cardiovascular risk factor revealed that being in the highest quintile of total DASH score (OR = 0.72, 95% CI 0.52–0.99) was negatively associated with hyperglycemia.

    Conclusions

    This study showed a positive relationship between DASH diet adherence and lower serum levels of glucose, triglycerides, and cholesterol. Prospective studies are needed to confirm these findings.

    Keywords: Cardiovascular diseases, diet therapy, hyperglycemia, hypertension, sodium}
  • لیلی مازار، مصطفی نصیرزاده*، محمدرضا میرکی
    زمینه و هدف

    فشار خون بالا به طور قابل توجهی خطر ابتلا به بیماری های قلبی، مغزی، کلیوی و سایر بیماری ها را افزایش می دهد. مطالعه حاضر با هدف بررسی تاثیر برنامه آموزشی مبتنی بر نظریه رفتار برنامه ریزی شده در خصوص دریافت نمک در افراد در معرض خطر پرفشاری خون شهر انار، رفسنجان انجام شد.

    مواد و روش ها

    مطالعه نیمه تجربی حاضر در میان 141 نفر (70 نفر گروه مداخله، 71 نفر گروه کنترل) با روش نمونه گیری تصادفی ساده انجام شد. داده ها بوسیله پرسشنامه مبتنی بر نظریه رفتار برنامه ریزی شده قبل و دو ماه بعد از مداخله جمع آوری شد و میزان نمک دریافتی روزانه از طریق آزمایش ادرار 24 ساعته ارزیابی شد. برنامه مداخله ای در شش جلسه آموزشی بصورت مجازی برگزار گردید. داده ها به کمک نرم افزار SPSS نسخه 18 و آزمون های آماری کای دو، تی مستقل و تی زوجی در سطح معنی داری 0/05 تحلیل گردیدند.

    یافته ها

    بعد از اجرای برنامه آموزشی، آزمون آماری تی مستقل، بین میانگین نمره ساختارهای نظریه دو گروه و نمک دریافتی (7/63 گرم در گروه مداخله در مقایسه با 12/01 در گروه کنترل) اختلاف معنی داری نشان داد (0/05>P). بیشترین تغییر ایجاد شده در ساختار باورهای رفتاری (21/42+) و کمترین تغییر در ساختار قدرت درک شده (1/87+) بود.

    نتیجه گیری

    با توجه به نتایج، برنامه آموزشی حاضر بر کاهش میزان نمک دریافتی اثر بخش بود. لذا ارایه برنامه های آموزشی بصورت حضوری و با مشارکت فعال دیگر افراد خانواده (دیگران مهم) با هدف توانمندسازی خانواده در کنترل و نظارت بر مصرف نمک دریافتی، پیشنهاد می گردد

    کلید واژگان: آموزش, نظریه, رفتار, فشار خون بالا, نمک, سدیم}
    Leili Mazar, Mostafa Nasirzadeh*, MohammadReza Miraki
    Background and Objectives

    Hypertension significantly increases the risk of heart, brain, kidney, and other diseases. This study aims to investigate the effect of educational intervention based on the theory of planned behavior (TPB) on the salt intake of people at risk of hypertension in Anar city, Rafsanjan.

    Materials and Methods

    The present semi-experimental study was conducted among 141 participants (intervention group=70, control group=71) with a random sampling method. Data were collected by a questionnaire based on TPB before and two months after the intervention, and the amount of daily salt intake was evaluated through a 24-hour urine test. The intervention program was held virtually in six training sessions. The data were analyzed by SPSS version 18 software using Chi-square, Independent t-test, and Paired t-test at significant level of 0.05.

    Results

    After the implementation of the educational program, the independent t-test showed a significant difference between the mean score of the theory constructs of the two groups and the amount of salt intake (7.63 grams per day in the intervention group vs. 12.01 in the control group) (P<0.05). The highest change was in behavioral beliefs (+21.42) and the lowest change in perceived power structure (+1.87).

    Conclusion

    According to the results, the current educational program was effective in reducing the amount of salt intake. Therefore, it is suggested to provide educational programs in person with the active participation of other family members (significant others) with the aim of empowering the family to control and monitor the salt intake.

    Keywords: Education, Theory, Behavior, Hypertension, Salt, Sodium}
  • Azam Doustmohammadian, Maryam Amini*, Marzieh Feyzpour, Sepideh Alibeky, Maryam Hajigholam Saryazdi
    Background and Objectives

    World health organization has identified unhealthy eating behaviors as one of the modifiable behavioral risk factors. Since sugar, salt, saturated and total fats, and trans-fatty acids are consumed much more than recommended, substantial decreases in these components as dietary risk factors are urgently needed. The study reviewed evidence on possible dietary risk decrease strategies to describe prevention programs.

    Materials and Methods

    In this study, SCOPUS, Web of Knowledge (ISI), EMBASE, PubMed, Google/Google Scholar, ProQuest, and Cochrane databases were searched from inception through 16 November 2022 to find policies that decreased consumption of dietary risk factors. Two researchers independently screened, appraised, and extracted the retrieved papers. Due to heterogeneity, only descriptive analyses were carried out.

    Results

    Four studies were included in the review. Three studies focused on decreasing sodium/salt and one on decreasing trans-fatty acids in industrial foods. Studies used various indicators and methods to indicate their achievements. The overall results based on the selected indicators demonstrated the projects' relative success in decreasing risk factors of foods.

    Conclusions

    Despite achievements in decreasing dietary risk factors in industrial foods, there is still a long way to go. Since various indicators show various aspects of the achievements, sufficient considerations in preparing sensitive and specific indicators are warranted.

    Keywords: Risk factors, Diet, Sodium, Sugar, Trans fatty acids}
  • Shiva Khanbabaie, Masoud Kiani*, Iraj Mohammadzadeh, Hadi Sorkhi, Mahmoud Hajiahmadi, Kiarash Saleki
    Background and Objective

    Despite the self-limiting nature of bronchiolitis, its severe forms require hospitalization. Electrolyte imbalance during bronchiolitis is common, however, the relationship between bronchiolitis severity and serum sodium (Na) levels has not been well studied. The purpose of this study was to investigate the relationship between serum Na level and bronchiolitis severity.

    Methods

    This cross-sectional study included hospitalized children with bronchiolitis at Amirkola Children’s Hospital, Babol, Iran, from May 2020 to May 2021. Diarrhea, underlying disease, glucocorticoid intake, and intravenous fluid therapy before admission were considered exclusion criteria. The Bierman-Pierson scale was used to evaluate the severity of the disease, and hyponatremia was divided into mild, moderate, and severe groups. Variables were analyzed using Statistical Packages for Social Sciences (SPSS) 26. A value of P<0.05 was considered significant.

    Findings

    Sixty-one children (55.7% male) with a mean age of 5.19 ± 4.36 months were enrolled in the study, with most (50.8%) belonging to the mild form of the disease. The mean serum Na levels based on the severity of bronchiolitis were 136.22 (SD: 2.99), 133.76 (SD: 3.88), and 130.50 (SD: 11.45) in the mild, moderate, and severe groups, respectively. There was a statistically significant relationship between serum sodium level and severity of bronchiolitis (P-value = 0.013).

    Conclusion

    The results showed that higher severity of bronchiolitis was associated with an increased risk of hyponatremia. Therefore, periodic monitoring and correction of hyponatremia in children with bronchiolitis, especially at younger ages, is necessary to improve the outcome of the disease.

    Keywords: Bronchiolitis, Child, Electrolyte imbalance, Prognosis, Sodium}
  • سهیل شمیری، وحید پوراسماعیل، سید محمدباقر نجارزاده
    مقدمه

    بیماری دیابت یکی از شایع ترین بیماری های متابولیک است که دارای عوارض ماکروواسکولار و میکروواسکولار شامل نفروپاتی، رتینوپاتی و نوروپاتی است. اختلالات الکترولیتی و ویتامین D نیز در بیماران دیابتی دیده شده است. هدف این مطالعه بررسی ارتباط سطح سرمی ویتامین D، سدیم و پتاسیم با نفروپاتی در بیماران مبتلا به دیابت نوع دو است.

    روش کار

    این مطالعه موردی-شاهدی بر روی 83 بیمار مبتلا به دیابت نوع 2 مراجعه کننده به بیمارستان 17 شهریور مشهد در سال 98 که به دو گروه دارای نفروپاتی و فاقد نفروپاتی تقسیم شدند، انجام گرفت. پروفایل چربی، کراتینین، FBS، HbA1c، GFR به همراه دیگر اطلاعات دموگرافیک بررسی شد. سطح سرمی ویتامین D با روش الایزا و سطح سرمی سدیم و پتاسیم با روش اسپکتروفتومتری جذب اتمی در تمام بیماران اندازه گیری شد. جهت آنالیز یافته ها از نرم افزار IBM-SPSS v.20 استفاده و سطح معنی داری آزمون ها کمتر از 05/0 در نظر گرفته شد.

    نتایج

    میانگین سنی 62/10±27/59 سال که شامل 45 مرد و 38 زن بود. شاخص توده بدنی (009/0=P-value)، مصرف دخانیات (005/0=P-value)، مدت ابتلا به دیابت، فشار خون سیستولیک و دیاستولیک، پتاسیم، FBS، HbA1c، کراتینین، GFR بین دو گروه تفاوت معناداری داشت (برای هر یک 0001/0=P-value). همچنین بین سطح سرمی ویتامین D (004/0=P-value) با بروز و سطح سرمی پتاسیم با شدت نفروپاتی ارتباط معناداری وجود داشت  (001/0=P-value).

    بحث و نتیجه گیری

    کنترل سطح سرمی ویتامین D و پتاسیم میتواند بر روی بروز و شدت نفروپاتی دیابتی تاثیر بگذارد، لذا کنترل این متغیرها در این بیماران توصیه میشود.

    کلید واژگان: دیابت, نفروپاتی دیابتی, ویتامین D, سدیم, پتاسیم}
    Soheil Shomeiri, Vahid Pouresmaeil, Seyed MohammadBagher Najarzadeh
    Introduction

    Diabetes is one of the most common metabolic diseases that has macrovascular and microvascular complications including nephropathy, retinopathy and neuropathy. Electrolyte and vitamin D disorders have also been seen in diabetic patients. The aim of this study was to investigate the relationship between serum levels of vitamin D, sodium and potassium with nephropathy in patients with type 2 diabetes.

    Material and Methods

    This case-control study was performed on 83 patients with type 2 diabetes referred to Shahrivar Hospital in Mashhad in 2019 who were divided into two groups with nephropathy and no nephropathy. Fat, creatinine, FBS, HbA1c, GFR profiles were evaluated along with other demographic information. Serum level of vitamin D was measured by ELISA method and serum level of sodium and potassium was measured by atomic absorption spectrophotometry in all patients. IBM-SPSS v.20 software was used to analyze the findings and the significance level of the tests was less than 0.05.

    Results

    The mean age was 59.27±10.62 years which included 45 men and 38 women. Body mass index (P-value=0.009), Smoking (P-value=0.005), Duration of Diabetes, Systolic and Diastolic Blood Pressure, Potassium, FBS, HbA1c, Creatinine, GFR were significantly different between the two groups. (P-value=0.0001 for each). Also, there was a significant relationship between serum vitamin D level (P-value=0.004) with the incidence and serum potassium level with the severity of nephropathy (P-value=0.001).

    Conclusion

    Control of serum levels of vitamin D and potassium can affect the incidence and severity of diabetic nephropathy, so control of these variables is recommended in these patients.

    Keywords: Diabetes, Diabetic nephropathy, Vitamin D, Sodium, Potassium}
  • Mahsa Abbaszadeh, Fatemeh Gorgani, Safa Javadi Tabrizi, Nasim Khajavi Rad, Narjes Zarei Jalalabadi *, Sahar Karimpour Reyhan

    Since the identification of COVID-19, its various manifestations have been reported in numerous studies. However, few studies have specifically examined the electrolyte imbalances seen in this disease. Patients with a definitive diagnosis of COVID-19 admitted to our hospital entered this retrospective cross-sectional study. Upon admission of the patients, a blood sample was sent for the analysis of the electrolytes. The relationship between electrolyte imbalances and disease severity, ICU admission, and mortality was also stated. Of 1072 hospitalized patients studied, 657 were men, and 415 were women. The prevalence of hypocalcemia (47.7%), hypophosphatemia (21.1%), hypomagnesemia (15.8%), and hyponatremia (13%) was higher compared to other electrolyte imbalances in these patients. Lower levels of sodium, calcium, and magnesium were seen in severe cases, while higher serum levels of potassium and phosphorus were detected in severe cases and ICU hospitalized patients. Causes such as albumin decrease in inflammation, the role of PTH, and the effect of vitamin D can play a role in hypocalcemia in these patients. In addition, electrolyte loss from the digestive tract can contribute to electrolyte imbalances. Because of the high prevalence of electrolyte imbalance in these patients, electrolyte monitoring is recommended in COVID-19 patients to ensure better care.

    Keywords: Hypocalcemia, Magnesium, Phosphorus, Calcium, Potassium, Sodium, COVID-19}
  • اکبر برزگر، میترا دربندی، عباس همتی ازندریانی، یحیی پاسدار *
    زمینه و هدف

    برچسب گذاری صحیح مواد غذایی می تواند به بهبود رژیم غذایی و سلامت کمک کند. با توجه به اهمیت سدیم در رژیم غذایی، تعیین مقدار سدیم مواد غذایی و مقایسه آن با مقدار گزارش شده بر روی برچسب های تغذیه ای از اهداف مطالعه حاضر بود.

    روش کار

    در این مطالعه 96 ماده غذایی پرمصرف در 5 گروه شامل فرآورده های گوشتی و پروتیینی، لبنیات، تنقلات، سس سفید، رب گوجه فرنگی و ماکارونی مورد بررسی قرار گرفت. مقدار سدیم با دستگاه فلیم فتومتر   (Halstead, Essex, England) اندازه گیری شد. تجزیه و تحلیل داده ها با استفاد ه از آزمون ویلکاکسون و ضریب همبستگی پیرسون انجام گرفت.

    یافته ها

    میانگین مقدار سدیم موجود در فرآورده های گوشتی و پروتیینی (04/183±35/409 میلی گرم) به طور معناداری بیشتر از مقدار گزارش شده بر روی برچسب های تغذیه ای (95/273±90/317 میلی گرم) بود (005/0p=). در گروه سس ها و رب ها میانگین مقدار سدیم بطور معنی داری کمتر از مقدار گزارش شده بر روی برچسب های تغذیه ای بود (002/0p=). در لبنیات و ماکارونی مقدار سدیم گزارش شده بر روی برچسب ها با مقدار واقعی تفاوت معناداری نداشت. در 67 درصد مواد غذایی مورد بررسی، مقدار سدیم گزارش شده بر روی برچسب های تغذیه ای با سدیم بکاررفته در مواد اولیه تطابق نداشت و کمتر یا بیشتر از مقدار واقعی گزارش شده بود.

    نتیجه گیری

    این مطالعه نشان داد مقدار سدیم گزارش شده بر روی برچسب های تغذیه ای مواد غذایی با مقادیر بکاررفته در مواد اولیه تفاوت قابل توجهی دارد. لذا کنترل دقیق سدیم در مراحل تولید فرآورده های غذایی و نظارت دقیق تر برچسب‫های تغذیه ای ضروری است.

    کلید واژگان: سدیم, فرآورده های گوشتی, لبنیات, تنقلات, برچسب تغذیه ای}
    A Barzegar, M Darbandi, A Hemati, Y Pasdar*
    Background & objectives

     Proper food labeling can help improve a diet and health. Due to the importance of sodium in the diet, determining the amount of sodium in food and comparing it with the amount reported on nutrition labels was the objective of the present study.

    Methods

     In this study, 96 high-consumption foods were examined in 5 groups, including meat and protein products, dairy products, snacks, white sauce, tomato paste, and macaroni. Sodium content was measured by a flame photometer (Halstead, Essex, England). Data were analyzed using the Wilcoxon test and Pearson correlation coefficient.

    Results

     Mean values of sodium found in meat and protein products (409.35±183.04 mg) were significantly higher than the amount reported on nutritional labels (317.90±273.95 mg) (p=0.005). For groups of white sauce and tomato paste, mean values of sodium were significantly lower than the nutritional labels (p=0.002). For dairy products and macaroni was no significant difference between the sodium content reported on the nutritional labels and the actual value. In 67% of examined food, the amounts of sodium did not match those reported by nutritional labels, being lower or higher than the value reported. 

    Conclusions

     This study demonstrated that the amount of sodium reported on nutritional labels significantly differed from the amounts used in raw materials. Therefore, it is essential to carefully control the amounts of sodium during food production processes and monitor nutritional labels.

    Keywords: Sodium, Meat Products, Dairy Products, Snack Food, Nutritional Labels}
  • هاله پرنیان نژاد
    زمینه و هدف

    با پیشرفت فناوری بیوانفورماتیک، اکنون می توان با سرعت بیشتری بر روی روش های نوین درمان سرطان مانند استفاده از توکسین های باکتریایی تحقیق کرد. در این مطالعه بیوانفورماتیکی، امکان اتصال زیرواحدهای توکسین شیگا (StxA و StxB) به پروتیین های اینترفرون گاما (IFNG)، پروستاگلاندین سنتتاز 2 (PTGS2) و سدیم/گلوکز کوترانسپورتر (SGLT1) بررسی شد تا بتوان گامی در جهت مهار سرطان برداشت.

    روش بررسی

    توالی های ژنی از پایگاه NCBI استخراج شد. برای توالی یابی و مدل سازی ساختار سه بعدی پروتیین ها به ترتیب از پایگاه های اطلاعاتی SWISS-MODE و jmol استفاده شد. اثر StxA و StxB بر پروتیین های IFNG، PTGS2 و SGLT1 با پایگاه ZDOCK با روش پهلوگیری مولکولی مورد ارزیابی قرار گرفت.

    یافته ها

    ساختار سه بعدی پروتیین ها نشان داد که پروتیین StxA مونومر نمی باشد و StxB دارای ساختارهای صفحه ای است که موجب اتصال آن به سطح سلول می-شوند. مارپیچ های آلفا و صفحات بتا در IFNG وجود دارد و این پروتیین مونومری فاقد ساختار سوم متقارن است. PTGS2 دارای ساختار کمپلکس و بزرگ متشکل از چندین مارپیچ آلفا و صفحه بتا است. در SGLT1 که پروتیینی غشاء گذر است، تنها مارپیچ های آلفا وجود داشت. میان کنش قابل توجهی بین پروتیین شیگا توکسین با هر سه پروتیین IFNG، PTGS2 و SGLT1 وجود دارد.

    نتیجه گیری

    یافته های این تحقیق افق جدیدی جهت مطالعات آزمایشگاهی اثر شیگا توکسین جهت بررسی توانایی تحریک سیستم ایمنی، کاهش رشد تومور و درمان سرطان با توجه به امکان اتصال آن به پروتیین های موثر در این روندها ارایه می دهد.

    کلید واژگان: سرطان, شیگا توکسین, اینترفرون گاما, پروستاگلاندین سنتتاز 2, سدیم, گلوکز کوترانسپورتر}
    Haleh Parniannejad
    Background and Objectives

    With of bioinformatics technology advancement, new methods of cancer treatment, such as the use of bacterial toxins, can now be explored more rapidly. In the present bioinformatics study, the probable attachment of Shiga toxin subunits to Interferon gamma (IFNG), Prostaglandin G/H synthase 2 (PTGS2), and Sodium/ glucose cotransporter 1 (SGLT1) was investigated to take a step towards cancer suppression.

    Methods

    The gene sequences were extracted from NCBI database. SWISS-MODE and jmol databases were used to detect the sequence and model the three-dimensional structure of proteins, respectively. The effect of StxA and StxB on IFNG, PTGS2 and SGLT1 proteins was evaluated with ZDOCK data base.

    Results

    Three-dimensional structure of proteins showed that the StxA protein was not a monomer, and that StxB had flat structures that bound it to the cell surface. Alpha helices and beta sheets are present in IFNG, and this monomeric protein lacks a symmetric tertiary structure. PTGS2 has a large complex structure consisting of several alpha helices and a beta sheet. In SGLT1, which is a transmembrane protein, only alpha helices were seen. There is a significant interaction between Shiga toxin protein and all three proteins IFNG, PTGS2 and SGLT1 by the method of molecular docking.

    Conclusion

    Findings of this study provide a new dedication for laboratory studies of the effect of Shiga toxin to evaluate its ability to stimulate the immune system, reduce tumor growth and treat cancer according to its ability to attach to the proteins which are effective in these processes.

    Keywords: Cancer, Shiga toxin, Interferon gamma, Prostaglandin G, H synthase 2, Sodium, glucose cotransporter 1}
  • Alireza Eskandarifar *, Peyman Taherkhani
    Background and Aim

    Electrolyte disorders in hospitalized children have several causes. One of the most important and common causes is using inappropriate maintenance intravenous fluids. This study aimed to investigate the effect and type of maintenance of intravenous fluids on the incidence of electrolyte disturbance in hospitalized children.

    Methods

    This research is a prospective cohort study. Non-surgical hospitalized children were divided into two groups based on the type of intravenous fluid received (normal saline [0.9% NaCl] or half saline [0.45% NaCl]). After matching two groups in terms of age and gender, the incidence of electrolyte disturbances (sodium and potassium) was evaluated in the two groups on the second and third days of the study.

    Results

    A total of 163 patients were included in this study. About 55.5% of the children were boys, and 44.5% were girls. The Mean±SD age of the children was 48.42±36.35 months, and their mean weight was 19.49±10.88 kg. Also, 50.6% of patients were in the half saline group and 49.4% in the normal saline group. Initially, serum sodium and potassium levels were normal in both groups. On the second and third days of the study, the incidence of serum sodium and potassium disorders was higher in patients who received half saline fluid, but this higher incidence was not statistically significant (P>0.05).

    Conclusion

    There is no significant difference between normal saline and half saline in terms of electrolyte disturbance if the patient’s clinical condition is judged correctly and an appropriate volume of fluids is prescribed.

    Keywords: Solutions, Fluid therapy, Child, Electrolytes, Sodium, Potassium}
  • Sara Jorairahmadi, Fatemeh Javaherforooshzadeh*, Farahzad Jannatmakan, Farhad Soltani, Liah Shidel Zadeh
    Background

    Coronary artery bypass grafting (CABG) surgery is a treatment option for coronary artery diseases. Cardiac arrhythmias during CABG surgery can lead to serious complications. Potassium ion concentration is a factor involved in such arrhythmias.

    Objectives

    This study aimed to investigate the relationship between potassium concentration and cardiac arrhythmias in CABG surgery.

    Methods

    This descriptive cross-sectional study was performed on 60 patients with the American Society of Anesthesiologists class I, II, and III undergoing CABG surgery at Golestan Hospital, Ahvaz, Iran. All patients underwent general anesthesia, and ventilator control was achieved by mechanical ventilation. The on-pump method was used for CABG. Potassium levels were measured at several time points during surgery. All cardiac arrhythmias were recorded. Mean arterial pressure (MAP), serum level of potassium, blood sugar, blood urea nitrogen (BUN), creatinine, calcium, magnesium, hemoglobin (Hb), and sodium were also recorded.

    Results

    The mean age of the patients was 60.87±7.35 years, and 45% of the subjects were female. Moreover, there was no statistically significant difference between the patients. There was a significant relationship between the changes in MAP, potassium, blood sugar, BUN, creatinine, calcium, and magnesium with the incidence of cardiac arrhythmias (P < 0.05). However, no significant relationship was noted between Hb and sodium levels with the incidence of cardiac arrhythmias (P < 0.05).

    Conclusions

    The changes in potassium levels increase the risk of cardiac arrhythmias and their complications.

    Keywords: Coronary Artery Bypass Grafting, Hyperkalemia, Hypokalemia, Sodium, Cardiac Arrhythmias}
  • Maryam Khalesi, Hamidreza Kianifar, Davoud Entezari, Zahra Chaichi *
    Background
    Chronic liver disease (CLD) in children is a growing health problem with significant morbidity and mortality. There is a specific susceptibility to electrolyte imbalance in chronic liver disease patients that can deteriorate their condition to hepatic encephalopathy. The aim of this study is to evaluate the electrolyte disturbance in CLD patients with and without hepatic encephalopathy.
    Methods
    This cross-sectional study was conducted in Ghaem Hospital, Mashhad University of Medical Sciences, Iran, during a six-year period. All patients below 14 years of age with chronic liver disease admitted to the pediatric gastroenterology department were included. Demographic data, laboratory tests, clinical manifestations and presence of hepatic encephalopathy were recorded in a checklist for each patient. Data was entered in SPSS software version 20. Qualitative data were analyzed using chi-square, and quantitative data were analyzed using independent t-tests. A P-value <0.05 was considered significant.
    Results
    Our study on 85 CLD patients showed that the serum sodium level and serum calcium level were significantly lower in patients with hepatic encephalopathy with P-Values of 0.001 and 0.02, respectively. Also, serum urea and bilirubinemia levels were significantly higher in the patients with hepatic encephalopathy with P-Values of 0.03 and 0.001 respectively.
    Conclusion
    It seems that reducing serum sodium and calcium level can be predictive of hepatic encephalopathy in pediatric patients with chronic liver disease
    Keywords: chronic liver disease, sodium, Calcium, Pediatrics}
  • هانیه گوهری، رقیه رحمانی بیلندی*، عباسعلی عباس نژاد، اعظم السادات محمودیان
    مقدمه

    زایمان زودرس، نگرانی شایع سازمان جهانی بهداشت است. پژوهش های انجام گرفته نشان دادند در عضلات صاف رحم کانال های سدیم و پتاسیم قرار رفته که در بروز انقباضات رحمی نقش دارند، لذا مطالعه حاضر با هدف بررسی سطح سرمی سدیم و پتاسیم با زایمان زودرس انجام گرفت.
    روش کار: این مطالعه مورد شاهدی در سال های 99-1398 بر روی 86 زن باردار مراجعه کننده به بیمارستان علامه بهلول گناباد، در دو گروه زایمان زودرس و زایمان ترم انجام گرفت. دو گروه از نظر متغیرهای شاخص توده بدنی ابتدای بارداری، رتبه بارداری و زایمان، سطح تحصیلات، میزان درآمد و وضعیت اشتغال، همسان سازی گروهی شدند. نمونه خون از مادران بعد از کسب معیارهای ورود در زمان پذیرش در لیبر، جهت بررسی سطح سرمی سدیم و پتاسیم گرفته شد. اطلاعات دموگرافیک و مامایی با استفاده از پرسشنامه و پرونده بستری بیمار جمع آوری شد. تجزیه و تحلیل داده ها با استفاده از نرم افزار آماری SPSS (نسخه 26) و آزمون های من ویتنی، کای دو و فیشر انجام گرفت. میزان p کمتر از 05/0 معنی دار در نظر گرفته شد.
    یافته ها: میانگین سطح سرمی سدیم در گروه مورد (11/21±98/123 میلی اکی والان بر لیتر) پایین تر از گروه شاهد (39/11±43/131 میلی اکی والان بر لیتر) و میانگین سطح سرمی پتاسیم در گروه مورد (92/5±66/4 میلی اکی والان بر لیتر) بیشتر از گروه شاهد (34/0±82/3 میلی اکی والان بر لیتر) بود، اما این اختلاف ها از نظر آماری معنادار نبود (05/0>p).
    نتیجه گیری: بین سطح سرمی سدیم و پتاسیم با زایمان زودرس ارتباطی وجود ندارد. برای بررسی ارتباط سدیم و پتاسیم سرم مادر با زایمان زودرس، نیاز به انجام تحقیقات بیشتر و بررسی سطح داخل سلولی سدیم و پتاسیم است.

    کلید واژگان: الکترولیت, پتاسیم, زایمان زودرس, سدیم}
    Haniye Gohari, Roghaieh Rahmani Bilandi *, Abasali Abasnezad, Azamsadat Mahmodian
    Introduction

    Preterm labor is a common concern of the World Health Organization. Studies have shown that Potassium and sodium channels in the smooth muscles of the uterus are involved in causing uterine contractions. Therefore, this study was performed with aim to evaluate the serum levels of sodium and potassium in preterm labor.

    Methods

    This case-control study was performed on 86 pregnant women referred to Gonabad Allameh Behlool Hospital in 2019-2020 in two groups of preterm and term delivery. The two groups were matched in terms of body mass index in early pregnancy, number of pregnancies and deliveries, level of education, income, and employment status. Blood sample was taken from the mothers after obtaining the inclusion criteria at the time of admission in labor to assess serum sodium and potassium levels. Demographic and midwifery information were collected using a questionnaire and patient's file. Data were analyzed by SPSS statistical software (version 26), and Mann-Whitney, Chi-square and Fisher tests. P< 0.05 was considered statistically significant.

    Results

    The mean serum sodium level in the case group (123.98±21.11 mEq/L) was lower than the control group (131.43±11.39 mEq/L) and the mean serum potassium level in the case group (4.66±5.92 mEq/L) was more than the control group (3.82±0.34 mEq/L) but these differences were not statistically significant (p> 0.05).

    Conclusion

    There is no relationship between serum sodium and potassium levels with preterm delivery. To investigate the relationship between maternal serum sodium and potassium and preterm delivery, further research is needed to evaluate the intracellular level of sodium and potassium.

    Keywords: electrolyte, Potassium, Preterm delivery, sodium}
  • رضا علیزاده نوایی، غزل محسنی، کیوان حیدری، اکبر هدایتی زاده عمران، محمود موسی زاده*
    سابقه و هدف

    در خصوص ارتباط بین الکترولیت های بدن با ابتلا به بیماری کووید19 یا شدت این بیماری شواهد متناقضی وجود دارد، که ترکیب این نتایج می تواند به رفع ابهامات کمک نماید. بر این اساس هدف مطالعه حاضر براورد ارتباط بین شاخص های الکترولیتی با ابتلا به کووید و شدت بیماری با استفاده از مرورسیستماتیک و متاآنالیز است.

    مواد و روش ها

    در این مطالعه، پایگاه های اطلاعاتی در سطح ملی و بین المللی با استفاده از واژه های کلیدی منتخب MeSH  مورد جستجو قرار گرفتند. ارزیابی کیفیت با چک لیست NOS انجام گرفت. میانگین تفاوت استاندارد شده شاخص های الکترولیت ها با پیامدهای ابتلا به کووید 19 و شدت ابتلا به کووید براورد شد.

    یافته ها

    پس از غربالگری مستندات، تعداد 12 مقاله واجد معیارهای ورود بودند. بر اساس نتایج متاآنالیز، میانگین تفاوت استاندارد شده سطح سرمی سدیم و پتاسیم، بین دو گروه فوت شده و فوت نشده مبتلایان به کووید به ترتیب برابر 0/22 (0/46، 0/03- :CI 95 درصد) و 0/14 (0/05، 0/22- :CI 95 درصد) براورد شده است. میانگین تفاوت استاندارد شده سطح سرمی سدیم، کلسیم و پتاسیم بین دو گروه مبتلایان به کووید 19 شدید و غیرشدید برابر 0/28- (0/17،0/27- :CI 95 درصد)، 1/07- (0/55-، 1/58- :CI 95 درصد) و 0/01- (0/27، 0/47- :CI 95 درصد) براورد شده است.

    استنتاج

    مطالعه متاآنالیز حاضر نشان داد که میانگین تفاوت استاندارد شده کلسیم در مبتلایان به فرم شدید بیماری کووید 19 به طور معنی داری کم تر از مبتلایان با فرم خفیف و متوسط می باشد.

    کلید واژگان: کووید 19, الکترولیت, سدیم, پتاسیم, کلسیم, کلراید, بیکربنات}
    Reza Alizadeh-Navaei, Ghazal Mohseni, Keivan Heydari, Akbar Hedayatizadeh-Omran, Mahmoo Moosazadeh*
    Background and purpose

    There are controversies on the association between electrolytes and Coronavirus disease 2019 (COVID-19) and its severity. Studies on these issues may help in resolving ambiguities. The purpose of this study was to assess the association between electrolyte indices and being infected with COVID-19 and developing severe symptoms using a meta-analysis.

    Materials and methods

    A thorough search was done in national and international electronic databases using Medical Subject Headings (MeSH) terms. Quality assessment was conducted by Newcastle-Ottawa scale (NOS) checklist. We estimated the standardized mean difference between electrolyte indices and the incident of COVID-19 infection and its severity.

    Results

    After screening the papers, 12 met the inclusion criteria. According to the meta-analysis results, the standardized mean differences for serum level of sodium and potassium between the dead and survived COVID-19 patients was estimated to be 0.22 (95% CI: -0.03, 0.46) and 0.14 (95% CI: -0.22, 0.50), respectively. The standardized mean differences for serum levels of sodium, calcium, and potassium between patients with severe and non-severe COVID-19 were estimated to be -0.28 (95% CI: -0.72, 0.17), -1.07(95% CI: -1.58, -0.55), and -0.10 (95% CI: -0.47, 0.27), respectively.

    Conclusion

    In this meta-analysis, the standardized mean difference for calcium was significantly lower in severe COVID-19 patients compared to that in patients with mild and moderate forms of the disease.

    Keywords: COVID-19, electrolyte, sodium, potassium, calcium, chloride, bicarbonate}
نکته
  • نتایج بر اساس تاریخ انتشار مرتب شده‌اند.
  • کلیدواژه مورد نظر شما تنها در فیلد کلیدواژگان مقالات جستجو شده‌است. به منظور حذف نتایج غیر مرتبط، جستجو تنها در مقالات مجلاتی انجام شده که با مجله ماخذ هم موضوع هستند.
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