Comparison of efficacy of amniotic membrane graft with usual dressings for burning wounds in Motahhari Hospital: 2005-2006

Human Amniotic membrane has been used as a biological dressing in the treatment of burns and the results were compared with ordinary dressing (use of antibacterial cream، silver sulfadiazine). The aim of this study was to compare the results of treatment between usual dressings and amniotic membrane graft. In this study 67 patients were randomly selected and divided in two groups: control (conventional dressing) and experimental (amniotic membrane graft). All of confounding factors were alike in two groups. The mean age of patients was 28. 15 years. Female and male were 22. 4% and 77. 6% of patients respectively. There was a significant lower duration of treatment، higher secondary albumin level، lower dressing times، and lower morphine administration in the experimental group (p< 0. 0001). These observations indicate that the amniotic membrane can prevent water loss، acts as a barrier against contamination and infection. So that، it aids the healing process and reduces morbidity and mortality. We conclude that use of human amniotic membrane as a biological dressing can be superior compared to conventional dressing.