The effect of magnesium sulfate on sore throat following surgery in patients undergoing general anesthesia
Author(s):
Abstract:
Introduction
Postoperative sore throat (POST), hoarseness of voice, and cough are common and undesirable complaints in patients receiving general anesthesia following endotracheal intubation. Magnesium (Mg) acts as antagonist at N-methyl-Daspartate (NMDA) receptor and thought to be involved in the management of pain. Furthermore, the presence of NMDA receptors on peripheral cells has been identified. The purpose of this study was to evaluate whether gargling of magnesium sulfate solution reduces postoperative sore throat (POST), hoarseness of voice, and cough. Materials And Methods
One-hundred seventy patients undergoing elective lumbar laminectomyand percutaneous nephrolithotomy (PCNL), were allocated randomly into two equal groups of control (gargling with placebo) and magnesium sulfate solution. Both groups gargled for 30 seconds 30 minutes prior to induction of anesthesia. The incidence of sore throat, hoarseness of voice, and cough at 0, 2, 4 and 24 hours postoperatively, was assessed. Results
The incidence of postoperative sore throat at 0, 2, 4, 24 hours postoperatively, was higher in control group (25-44.7% versus 4.7-20%; p<0.0001). Although the incidence of postoperative hoarseness and cough was higher among control group (6.5-16.5% versus 1.2-8.2% for hoarseness,and 2.4-9.4% versus 5.9-14.1% for cough); no significant statistically difference was found between two groups except for postoperative hoarseness at 24 hour (p=0.01).Conclusion
Gargling with 10cc of Mg sulfate solution 20%, 20 minutes before induction of anesthesia reduces the incidence of postoperative sore throat, significantly. Hoarseness is also decreased at 24 hour postoperatively, but is not effective to reduce the incidence of cough after surgery.Keywords:
Language:
Persian
Published:
Iranian Journal Of Anaesthesiology and Critical Care, Volume:35 Issue: 3, 2013
Page:
36
https://magiran.com/p1210258
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!