Selective Voltammetric Determination of Carbidopa in the Presence of Uric Acid Using a Modified Carbon Nanotube Paste Electrode

This paper reports the selective determination of carbidopa (CD) in the presence of uric acid (UA) using 2,7-bis(ferrocenyl ethyl)fluoren-9-one modified carbon nanotube paste electrode (2,7-BFCNPE) in 0.1 M phosphate buffer solution (PBS) pH 7.0. In PBS of pH 7.0, the oxidation current increased linearly with two concentration intervals of CD, one is 0.2 to 22.0 μM and, the other is 22.0 to 750.0 μM. The detection limit (3σ) obtained by DPV was 68.0 nM. The practical application of the modified electrode was demonstrated by determining CD in urine samples.