The Evaluation of prevalence of 25 _hydroxy vitamin D in hemodialysis patient

The level of 1’25 dihydroxy vitamin D begins to decline early in the course of chronic kidney disease, owing to the decline in proximal tubular production of 1α hydroxylase. Vitamin D plays an essential role in muscle function, immune system, bone metabolism and cardiovascular.in addition to 1, 25 dihydroxy vitamin D, the level of 25 hydroxy vitamin D is decreased in uremic patients. This cross sectional study was performed in summer 1391 in hemodialysis centers of Loghman Hakim and Ashrafi Esfahani hospital. Inclusion criteria were adequate dialysis delivery with KT/V>1.2, age>15, serum albumin>3.5 and not missing dialysis more than two sessions in each month. The exclusion criteria were being on dialysis less than 3 months, Presence of Catabolic states (malignancy, and HIV).Calcium, Phosphor, Hemoglobin, parathyroid hormone (PTH),25 hydroxy D (25 OHD) and C-Reactive protein (CRP) were tested for all. 135 Patients, 62 were male (51%) and 66 were Females (69%) 85 patients (63%) had 25 OHD deficiency.43 patients had normal level and 7 Patients (5.2%) had toxic level. This study showed that 25 OHD Deficiency is common in our country and 25OHD supplements are useful for these patients. Therefore It was recommended to test the level of 25 OHD of the patients frequently. The removal of 25 OHD would result in functional improvement of patients. Acknowledgement:The authors especially acknowledge for the nurses of dialysis units for their collaboration. Confelict of interest: None declared.