The antibiotic resistance pattern of gram-negative bacilli isolated from urine cultures of adult outpatients admitted to Vali Asr Hospital of Fasa Clinical Laboratory in 2012-13

Urinary tract infections are common infections in humans which according to current statistics have been observed in 30-50% 0f them. The indiscriminate use of antibiotics increases the resistance to treatment. The aim of the present study is detection of urinary tract infection causes (Enterobacteriaceae) and their antibiotic susceptibility patterns in outpatients in Fasa Vali- Asr hospital laboratory during 2012 & 2013. This descriptive study was performed on 1108 positive urine culture of adults & outpatients in laboratory of Vali-Asr hospitals in Fasa in 2012 and 2013. The urine samples were cultured in Blood agar and MaCconkey agar. The bacterial identification procedures with conventional biochemical tests were performed. Antibiotic susceptibility testing was carried by disk diffusion method according to CLSI. In 92.12% of samples, UTI was caused by Enterobacteriaceae. The bacterial isolates show highest resistance rate to Cotrimoxazole (57.4%), Cefalotin (55.6%), Cefixime (45%) and Nalidixic acid (43.6%) and highest susceptibility rate to Ciprofloxacin (74%), Gentamicin (65%), Nitrofurantoin (64.9%) and Ceftriaxone (58.2%). Our study showed that gram- negative bacilli, especially E.coli are dominant bacterial pathogens that cause urinary tract infections in Fasa. Most isolated species showed a high resistance to common antibiotics.