Seroprevalance Determination of Cytomegalovirus Infection in Women in Their Reproductive Age Referred to Shahid Mofateh Clinic of Yasuj, Iran, in 2013

According to the maternal health, and the fact that cytomegalovirus infection is associated with abortion and the incidence of fetal malformations, the aim of this study was to determine the seroprevalance of cytomegalovirus infection of women in the reproductive age. The present cross-sectional study was conducted on women of childbearing referred to Yasuj Mofatteh clinic in 2013. Ninety-four eligible women (married women aged 17 to 45 years) were selected by random-stratified sampling. After completing the questionnaire which included demographic and clinical characteristics, blood samples were collected and IgG & IgM antibodies titers against CMV were measured by ELISA. The collected data was analyzed by SPSS and statistical tests and independent T-test & chi-square. 98.9% of the participants (93 eligible women) were positive for anti-CMV IgG antibody, whereas the IgM antibody in only one patient (1.1 %) was border line. Also no significantassociation was observed between the IgG and IgM antibodies and clinical manifestations with demographic variables. Moreover, the titer of IgG and IgM antibodies and clinical manifestationsassociated with demographic variables was not significant (p>0.05). The results indicated that exposure to cytomegalovirus in women at childbearing age was significant in Yasuj and need serious care in order to prevent complications and congenital malformation felt in this group.