Effect of Twelve Weeks Combined Exercise (Aerobic- Resistance) on Plasma Levels of Myostatin in Obese Adolescents

The aim of this study was assessing effect of twelve weeks combined exercise (aerobic-resistance) on plasma levels of Myostatin in obese youth. This study is a semi experimental one. Thirty obese adolescents willing to cooperate were divided in two groups: experimental group (height 165.28 cm, weight 85.53 kg, age 13.73 years old) and control group (height 164.54 cm, weight 83.02 kg, age 13.93 years). Then, the experimental group covered the combined exercise program (aerobic training consisted of running on a treadmill for 20 minutes and (resistance training with the intensity of 70% in one repetition maximum (1RM) with 10 repetitions per movement for 2 rounds) for12 weeks. While the control group received no intervention and just were observed. Blood samples were collected in two stages, 48 hours before and after exercise to measure the Myostatin plasma levels. Paired t-test was used for intergroup comparisons and independent t-test was used for comparison between two groups. Findings showed that Weight Values)P=0.000(, body fat percentage)P=0.000(, BMI)P=0.000 (and myostatin)P=0.000(after 12 weeks performing of combined exercise significantly decreased and VO2max)P=0.012 (significantly increased (p<0.05). We can conclude that after 12 weeks combined exercise, weight, body fat percentage, body mass index and plasma levels of Myostatin will reduce in obese youth. Thus, doing a combined training program may be effective in decreasing Myostatin, muscle atrophy prevention and loss of muscle mass of obese youth.