iman zakavi

Stragol herbal composition and aerobic exercise may have additional positive effect on inflammation process after myocardial infarction (MI). So, this study aimed to analyze the effect of aerobic exercise and stragol consumption on plasma levels of IL-6, TNF-α, and IL-10 following a MI in male Wistar rats.

Male wistar rats were subjected to coronary artery occlusion surgery and then MI was confirmed by electrocardiography. Totally, 32 male rats (aged 8-10 weeks) were randomly devided into four groups. The aerobic exercises has lasted for six weeks (three training sessions in every week). Stragol consumption group as well as combined group have received 9.58 mL/day of stragol drop. The data has been analyzed according to one-way ANCOVA test and Bonferroni test.

None of the interventions had a significant difference on IL-10 and TNF-α. But there was a significant impact between the adjusted mean IL-6 in all studied groups (p=0.003). The aerobic exercises and stragol had no significant impact on IL-6 separately whereas the combined intervention decreased IL-6 following a MI in rats (p=0.003).

It seems that aerobic exercises and administration of stragol drops is a combination that can improve the inflammatory state after MI.

The application of supplements, herbal extracts, and exercise training for treatment of diseases and reducing chronic inflammation has been increased progressively among people. Thus, the aim of this investigation was to study the combined aquatic extract of Ferulago angulata boiss with aerobic exercise on pro‑inflammatory indices in obese males.

In this semi‑experimental study, forty young obese men (mean and standard deviation of age 34.59 ± 2.24 years, body mass index (BMI) 33.14 ± 2.75 kg/m2 ) were selected by purposed sampling and were randomly divided into four equal groups (n = 10), training, training‑supplementation, supplementation, and control. Participants in the supplementary groups received 50 mg/ml F. angulata extracts daily for 12 weeks. Aerobic training program included 12 weeks of training, 3 sessions/week, and each session was 20 min at 60%–%–70% of maximal oxygen consumption. Blood samples were taken from the participants 48 h before and after the intervention in fasting state. Data were analyzed using dependent t‑test, one‑way analysis of variance, and post hoc Tukey test at a significant level of P < 0.05.

After 12 weeks of exercise and supplementation, levels of interleukin (IL)‑6 (P = 0.001), IL‑18 (P = 0.03), IL‑1 β (P = 0.001), tumor necrosis factor alpha (P = 0.001), weight (P = 0.001), BMI (P = 0.001), body fat percent (P = 0.001), and waist‑hip ratio (P = 0.001) decreased significantly and the mean changes of these indicators in training + supplementation group were significantly augmented as compared to the other three groups.

It appears that aerobic training plus F. angulata extract consumption have better effect on improvement of serum inflammatory factors in obese young men.

The purpose of the present study was to examine the effect of a progressive resistance-training program beside an energy deficit diet on body Composition, insulin resistance and plasma adiponectin levels in overweight adult men.
Twenty-five overweight men (age =32.1 ± 4.3 years, BMI =28.9 ± 1.3 kg.m-2) were randomly assigned into one of the two groups: resistance training+ diet (RD, n =15); and diet only (DO, n =12). Both groups undertook a 12-week weight loss program using a moderate isocaloric energy deficit.
After 12 weeks intervention, there was equivalent significant weight loss for both groups (p <0.01). Total and abdominal fat mass, fasting insulin concentration and HOMA-IR score were decreased in both groups (p <0.01). All previously mentioned variables except fasting insulin levels were more significantly reduced in RD compared to DO group. There was a significant decrease in lean body tissue only in DO (p <0.01) group. We did not find any significant changes in plasma adiponectin concentration of the experimental groups. Reduction in insulin resistance had a significant positive correlation with abdominal and total fat loss (p < 0.05) and a negative correlation with lean mass loss (p < 0.05).
Adding a progressive resistance-training program to an energy deficit diet, without any change on magnitude of weight loss could prevent the loss of lean body mass and improve the reduction of total and abdominal fat mass and insulin resistance. Moreover, the change in body composition and insulin resistance was accompanied with no significant change in plasma adiponectin.

The aim of the present study was to evaluate the impacts of chavir aquatic extract (Ferulago angulata Boiss) along with aerobic exercises on serum levels of interleukin-10 (IL-10) and C-reactive protein (CRP) of obese males. In this study, 40 males with body mass index (BMI) >30 kg/m2 and average age of 33.63 ± 4.78 years were randomly categorized into 4 groups of 10 individuals as control, combination (using the aquatic extract of chavir along with aerobic exercises), consumption of chavir aquatic extract, and aerobic exercises. The aerobic exercises in both groups of combination and aerobic exercises consisted of running on treadmill for 20 minutes in 60%-70% maximum oxygen uptake (VO2max). The aquatic extract consumption and the combination groups had to take 50 mg/mL/d of chavir aquatic extract every time. The control group received no intervention. Based on intragroup comparisons, body weight and BMI significantly decreased in the combination group; the content of body fat and waist-hip ratio (WHR) also reduced significantly in the aerobic, combination, and aquatic extract groups. In intergroup and intragroup comparison, CRP faced with a significant decrease in all groups (aerobic exercises, Ferulago aqueous extraction, and combination groups) and a considerable increase was also observed in the combination group regarding IL-10 variable. Therefore, the effectiveness of the combination group regarding increasing IL-10 and decreasing CRP is more than other groups. As a result, using aqueous extract of F. angulata and doing aerobic exercise for 3 months reduced risk factors – cardiovascular, body composition, and increasing anti-inflammatory in obese men. Consequently, the effect of combination group to reduce the proinflammatory indexes and body factors of obese males was more compared to that of the other groups.

Obesity and Overweight decrease plasma levels of ghrelin and obestatin. Studies on the effects of exercise on ghrelin and obestatin, especially in human, are few and limited. The aim of this study was assessing effect of 12 weeks combined exercise (Aerobic-resistance) on plasma levels of ghrelin and obestatin in obese adolescents.
Thirty obese adolescents were willing to cooperate voluntarily; they were randomly divided in two groups: experimental group (BMI 31.046±3.55Kg/m2, BF% 34.74±2.71) and control group (BMI 30.404±3.198Kg/m2, BF% 35.06±2.465). Then, the experimental group received combined exercise program aerobic training consisted of running on a treadmill for 20 minutes at 60-70% of maximal oxygen consumption (VO2max) and (intensity resistance training 70% of one repetition maximum (1RM) for 2 sets of 10 repetitions per movement) for 12 weeks (three sessions per week). The control group received no intervention but were followed. Variables including weight, body fat percentage, BMI, VO2max were measured in both groups before and after exercises. Blood samples were collected in two stages, 48 hours before and after exercise to measure of plasma levels of ghrelin and obestatin. Paired t-test was used for intergroup comparisons and independent t-test was used for comparison between the two groups. All statistical calculations were performed through SPSS software version 19.
The findings showed that values of weight, body fat percentage, BMI performed after 12 weeks of combined exercise (aerobic - resistance) significantly decreased. VO2max, plasma levels of ghrelin and obestatin significantly increased (p We can conclude that 12 weeks of combined exercise (aerobic - resistance) reduced weight, body fat percentage, and BMI; while it increased plasma levels of ghrelin and obestatin.

Brain-derived neurotrophic factor (BDNF), which is structurally similar to nerve growth factor is produced in the hippocampus and is one of the factors that is reduced by age due to lack of activity. Reduced BDNF has effects on memory, learning and cognition, behavioral disorders, food intake and energy metabolism that can be compensated with exercise and the incidence of Alzheimer can be prevented. The aim of this study was to investigate the effect of Pilates exercise on serum BDNF level in elderly men. 20 elderly men were randomly divided into experimental and control groups with mean age (control: 65 ± 2.67, experimental: 64 ± 2.62) and mean weight (control: 73 ± 3.59, experimental: 71 ± 3.54). Fasting blood samples were collected 24 hours before and 24 hours after the end of protocol. Then, experimental group received Pilates exercise for 12 weeks, 5 sessions per week, and 60 minutes per sessions while the control group received no intervention but were followed. Paired t test was used for intragroup comparisons and independent t test was used for intergroup comparison. Findings showed that BDNF levels significantly increased in experimental group compared to control (P

The aim of this study was assessing effect of twelve weeks combined exercise (aerobic-resistance) on plasma levels of Myostatin in obese youth. This study is a semi experimental one. Thirty obese adolescents willing to cooperate were divided in two groups: experimental group (height 165.28 cm, weight 85.53 kg, age 13.73 years old) and control group (height 164.54 cm, weight 83.02 kg, age 13.93 years). Then, the experimental group covered the combined exercise program (aerobic training consisted of running on a treadmill for 20 minutes and (resistance training with the intensity of 70% in one repetition maximum (1RM) with 10 repetitions per movement for 2 rounds) for12 weeks. While the control group received no intervention and just were observed. Blood samples were collected in two stages, 48 hours before and after exercise to measure the Myostatin plasma levels. Paired t-test was used for intergroup comparisons and independent t-test was used for comparison between two groups. Findings showed that Weight Values)P=0.000(, body fat percentage)P=0.000(, BMI)P=0.000 (and myostatin)P=0.000(after 12 weeks performing of combined exercise significantly decreased and VO2max)P=0.012 (significantly increased (p<0.05). We can conclude that after 12 weeks combined exercise, weight, body fat percentage, body mass index and plasma levels of Myostatin will reduce in obese youth. Thus, doing a combined training program may be effective in decreasing Myostatin, muscle atrophy prevention and loss of muscle mass of obese youth.

The different effects of exercise on obesity in obese adolescents have not sufficiently been studied.. This study aimed to investigate the effect of an eight-week rope skipping exercise on interleukin-10 (IL-10) and C-reactive protein (CRP) in obese and overweight adolescents..Patients and In this semi-experimental study, using purposive convenience sampling 30 overweight and obese teens were randomly divided into two groups: the experimental (height 165.28 cm; weight 85.53 kg and age 13.73 years old) and control (height 164.54 cm; weight 83.02 kg and age 13.93 years old) groups. Then the experimental group performed the eight-week rope skipping exercise program while the control group did not receive any intervention and was only following up. Before and after the exercise, the variables including weight, fat percentage, body mass index (BMI) and the maximum oxygen consumption (Vo2max) in both groups were measured. To assess the amount of serum IL-10, CRP, 48 hours before and after the exercise, fasting blood samples were taken during the two-stage mode. The correlated t-test and the independent t-test were used to compare the intragroup and intergroup relationships, respectively.. There was no significant change in the serum levels of IL-10 (P > 0.05); however, the intragroup comparison in the experimental group showed a significant increase in serum levels of IL.10 (P < 0.05). Moreover, the variables of the weight, BMI, fat percentage, V02max and CRP were significantly changed (P < 0.05).. A rope skipping protocol increases the anti-inflammatory index, reduces the risk of cardiovascular disease, and improves the body compounds and immune system of the obese and overweight teens..

Stumbling or falling is a major health problem among the elderly which accounts for their majority of physical injuries such as pelvic fractures, disability, loss of independency and even death. The goal of the study was comparison of the effect of aerobic and resistance exercise on static and dynamic balance in old men. A quasi-experimental study was conducted and thirty elderly males, who were referred to Jahandidegan institute of Borujen, were divided randomly in three empirical groups subdividing aerobic, resistance and control group. 24 hours before the start of and 24 hours after completion of eight weeks -aerobic and resistance exercise, all participants went under static and dynamic balance examination. The results were analysed by SPSS software edition 19. Mean and standard deviation of dynamic balance scores before the exercise for the resistance, aerobic and control groups were 1017.6±212.7, 930.5±238.2, 1119.6±287.3 and after eight weeks exercise were 851.7±155.5, 743.4±130.1, 1220.06±226.9 respectively. On the other hand, Mean and standard deviation of static balance scores before the exercise in resistance, aerobic and control groups were 2280.3±2286.2, 3534.9±4455.4, 1284.1±231.4 and after eight weeks exercise were 5563.4±8014.6, 6089±7888.4, 1297.1±214.4 respectively. ANOVA test revealed that the difference in changes of three groups were not statistically significant (P > 0.05). Despite marginal correlation between static and dynamic balance as the outcomes of aerobic and resistant exercise these activities are proposed because such the exercises reduce incidence of falling events and related-injuries; and also risk of independency among older adults.

interleukin-18, and C-Reactive protein (CRP) are two Cardio - Vascular risk factors that have been raised in recent years and independently show the risk of atherosclerosis. The purpose of this study is to evaluate the effect of eight weeks roping on IL-18 and C-reactive protein in overweight and obese adolescents. This is a semi experimental study in which Thirty overweight or obese adolescents willing to cooperate voluntarily were randomly divided in two groups: experimental group (15 people, height 165.28 cm, weight 83.02 kg, age 13.73 years old and BMI 31.046) and control group (15 people, height 164.54 cm, weight 83.02 kg, age 13.93 years and BMI 30.404). Then, the experimental group was influenced by increasing roping exercise program which consisted of 8 sessions per week. While the control group received no intervention but were just followed. Variables including weight, body fat percentage, body mass index (BMI), VO2max were measured in both groups before and after exercises. Blood samples were collected in two stages, 48 hours before and after exercise to measure leukocytes, lymphocytes, neutrophils and levels of IL-18, CRP levels. Paired t-test was used for intergroup comparisons and two way variance analysis was used for comparison between two groups. All statistical calculations were performed by SPSS software version 19. After eight weeks roping in within groups comparison the variables weight (P=0.001), BMI (P=0.001), percent body fat (P=0.001), IL-18 (P=0.001) and CRP (P=0.001) were significantly decreased but in between groups comparison with variance analysis the variables weight (P=0.501), BMI (P=0.257), percent body fat (P=0.068), had an insignificant decrease, IL-18 (p=0.001) and CRP (p=0.001) significantly decreased and V02max (P=0.009) significantly increased. Based on these results, roping exercise reduced IL-18 and decreased inflammation in overweight and obese adolescents, so it would be possible and useful to perform this exercise to prevent and reduce atherosclerosis in obese adolescents.