Study the Seasonality of Primary TB Infection in Children Under 4 Years

Tuberculosis is a contagious disease and one of the most deadly infectious diseases in the world. About a third of the world's people are infected with the tuberculosis. During 5 years of tuberculosis infection, 10% of cases involved disease. Tuberculosis can affect virtually every organ, most importantly the lungs. Tuberculosis treatment needs a long-period use of antibiotics with numerous side effects. The purpose of this study is survey of Seasonality primary TB infection in children under 4 years In Mashhad health centers from 2004-2008. It is a descriptive analysis cross-sectional study among 33 children fewer than 4 years with primary tuberculosis attending to health centers of Khorasan Razavi from 2003 to 2008. Tuberculosis diagnoses newly were confirmed with sputum smear, culture and biopsy. In 33 cases primary tuberculosis between ages 0-4 years, the average age were 2/8 ± 1/3 years. 48.5% were female. The most common incidence of tuberculosis was in winter (%36/4) and fall (30/3). There is not a significant relationship between of Seasonality and age, sex, nationality, tuberculosis vaccination, tuberculosis contact history. The distribution of tuberculosis in the fall and winter season with the theory that the presence of TB infection with an increased in overcrowding, poor ventilation and the increased prevalence of cough caused by other respiratory infections in cold weather related, is justified.