Effect of 8 weeks of Aerobic Training and using Chicory extractive supplementation on Serum levels of ALT and AST Enzymes in women with Fatty Liver

Non-alcoholic fatty liver disease (NAFLD) is a growing metabolic disease. Life-style modifications such as healthy diet and sport have been recommended for patients with fatty liver. Chicory has drawn attention for its hepatoprotective effects. This study was performed with aim to investigate the effect of eight weeks aerobic training along with chicory extractive supplementation on serum levels of Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) enzymes in women with fatty liver.
This semi-experimental pre and post-test study was performed on 30 NAFLD women in Bardeskan city in 2014. They were randomly divided into three groups of 10 cases: 1- training supplement, 2- training placebo, 3- supplement. Training groups performed training program comprised of aerobics exercises, 3 sessions per week for 8 weeks. During the experimental period, participants received either 200 mL daily chicory extractive (2.5g/100mL) for 8 weeks or placebo. Prior and 48h after the experimental period, blood samples were taken to be analyzed for serum levels of ALT and AST. Data was analyzed by SPSS software (version 20), and analysis of variance and coefficient t and LSD. P There was significant difference among three groups in decreased serum levels of ALT and AST (P=0.0001), and this decrease was higher in training supplement group than other groups (P≤0.05)
Simultaneous consumption of chicory supplementation along with aerobic training have more effect on AST and ALT reduction in women with fatty liver.