Fluctuations in Gene Expression of Hypoxia-Inducible Factors (hif-1, hif-2) During Ontogeny of Persian Sturgeon (Acipenser persicus Borodin, 1897)

Oxygen concentration the environment and cellular organisms is one of the effective factors during normal development of organisms. In the present study, the transcription levels of the hypoxia-inducible factors (hif-1, hif-2) were evaluated during development of an ancient fish species Acipenser persicus, in the normal oxygen density of environment. The transcription of hif-1, hif-2 detected in all developmental time-points defined, from embryo to juvenile stages. Target genes transcriptions were normalized using RPL6 as reference gene. Changes in normalized hif-1, hif-2 mRNA expression were statistically significant throughout developmental points (p